Results
Title

The development history of Germfree animal model and its application in the study of microbiota-related diseases.

Authors

Rui Guo; Yifeng Gu; Lanjuan Li

Abstract

A germ-free animal is an experimental animal with no live microorganisms and parasites in its body. It is a powerful experimental tool for the study of the relationship between microbiota and host health. We reviewed the development history of germ-free animals and provide an overview of their application in medical research, such as intestinal microbiota, immunology and oncology. We provide references for research on microbe-related diseases.

Subjects

GERMFREE animals; ANIMAL models in research; GUT microbiome; MEDICAL research; LABORATORY animals

Publication

Thai Journal of Veterinary Medicine, 2023, Vol 53, Issue 1, p1

ISSN

0125-6491

Publication type

Academic Journal

DOI

10.14456/tjvm.2023.1