Results
Title

基于AHP-EWM结合Box-Behnken响应面法优化黄芩多指标成分的微波提取工艺.

Authors

蒋佳丽; 刘婷; 李宇浩; 韩伟; 薛东升

Abstract

Combined with analytic hierarchy process-entropy weight method, the effects of microwave power, liquid-solid ratio, extraction time, extractions times and particle size were investigated in single factor test using the yield of baicalin, wogonoside, baicalein, wogonin and paste yield as the indexes. Taking the comprehensive score as the response value, the microwave extraction process of Scutellaria baicalensis was optimized by the Box-Behnken response surface test at four factors and three levels. The micro-morphological changes of medicinal powder before and after extraction were observed by SEM. The results showed that the optimal extraction process conditions obtained by BBD response surface method were microwave power of 390 W, liquid-solid ratio of 56 mL/g, extraction time of 472 s, and particle size of 80 mesh (180 μm). At this time, the yield of baicalin, wogonoside, baicalein and wogonin were 16.82%, 3.46%, 0.30% and 0.31%, respectively, the paste yield was 73.73%, and the comprehensive score was 10.75. The extraction effect of this process is better than that of common reflux extraction, and the subjectivity and objectivity of the evaluation results are realized.

Subjects

PHARMACEUTICAL powders; CHINESE skullcap; ANALYTIC hierarchy process; MICROWAVES; OBJECTIVITY

Publication

Journal of East China University of Science & Technology, 2024, Vol 50, Issue 5, p678

ISSN

1006-3080

Publication type

Academic Journal

DOI

10.14135/j.cnki.1006-3080.20230927001