Works matching AU Easton, Douglas


Results: 197
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    Risk models for familial ovarian and breast cancer.

    Published in:
    Genetic Epidemiology, 2000, v. 18, n. 2, p. 173, doi. 10.1002/(SICI)1098-2272(200002)18:2<173::AID-GEPI6>3.0.CO;2-R
    By:
    • Antoniou, Antonis C.;
    • Gayther, Simon A.;
    • Stratton, John F.;
    • Ponder, Bruce A.J.;
    • Easton, Douglas F.
    Publication type:
    Article
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    Chromatin interactome mapping at 139 independent breast cancer risk signals.

    Published in:
    Genome Biology, 2020, v. 21, n. 1, p. 1, doi. 10.1186/s13059-019-1877-y
    By:
    • Beesley, Jonathan;
    • Sivakumaran, Haran;
    • Moradi Marjaneh, Mahdi;
    • Lima, Luize G.;
    • Hillman, Kristine M.;
    • Kaufmann, Susanne;
    • Tuano, Natasha;
    • Hussein, Nehal;
    • Ham, Sunyoung;
    • Mukhopadhyay, Pamela;
    • Kazakoff, Stephen;
    • Lee, Jason S.;
    • Michailidou, Kyriaki;
    • Barnes, Daniel R.;
    • Antoniou, Antonis C.;
    • Fachal, Laura;
    • Dunning, Alison M.;
    • Easton, Douglas F.;
    • Waddell, Nicola;
    • Rosenbluh, Joseph
    Publication type:
    Article
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    Genetic susceptibility to breast cancer

    Published in:
    Molecular Oncology, 2010, v. 4, n. 3, p. 174, doi. 10.1016/j.molonc.2010.04.011
    By:
    • Mavaddat, Nasim;
    • Antoniou, Antonis C.;
    • Easton, Douglas F.;
    • Garcia-Closas, Montserrat
    Publication type:
    Article
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    Polyunsaturated fatty acids and prostate cancer risk: a Mendelian randomisation analysis from the PRACTICAL consortium.

    Published in:
    2016
    By:
    • Khankari, Nikhil K;
    • Murff, Harvey J;
    • Zeng, Chenjie;
    • Wen, Wanqing;
    • Eeles, Rosalind A;
    • Easton, Douglas F;
    • Kote-Jarai, Zsofia;
    • Al Olama, Ali Amin;
    • Benlloch, Sara;
    • Muir, Kenneth;
    • Giles, Graham G;
    • Wiklund, Fredrik;
    • Gronberg, Henrik;
    • Haiman, Christopher A;
    • Schleutker, Johanna;
    • Nordestgaard, Børge G;
    • Travis, Ruth C;
    • Donovan, Jenny L;
    • Pashayan, Nora;
    • Khaw, Kay-Tee
    Publication type:
    journal article
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    BRCA Challenge: BRCA Exchange as a global resource for variants in BRCA1 and BRCA2.

    Published in:
    PLoS Genetics, 2018, v. 14, n. 12, p. 1, doi. 10.1371/journal.pgen.1007752
    By:
    • Cline, Melissa S.;
    • Liao, Rachel G.;
    • Parsons, Michael T.;
    • Paten, Benedict;
    • Alquaddoomi, Faisal;
    • Antoniou, Antonis;
    • Baxter, Samantha;
    • Brody, Larry;
    • Cook-Deegan, Robert;
    • Coffin, Amy;
    • Couch, Fergus J.;
    • Craft, Brian;
    • Currie, Robert;
    • Dlott, Chloe C.;
    • Dolman, Lena;
    • den Dunnen, Johan T.;
    • Dyke, Stephanie O. M.;
    • Domchek, Susan M.;
    • Easton, Douglas;
    • Fischmann, Zachary
    Publication type:
    Article
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    Genome-wide association study identifies novel breast cancer susceptibility loci.

    Published in:
    Nature, 2007, v. 447, n. 7148, p. 1087, doi. 10.1038/nature05887
    By:
    • Easton, Douglas F.;
    • Pooley, Karen A.;
    • Dunning, Alison M.;
    • Pharoah, Paul D. P.;
    • Thompson, Deborah;
    • Ballinger, Dennis G.;
    • Struewing, Jeffery P.;
    • Morrison, Jonathan;
    • Field, Helen;
    • Luben, Robert;
    • Wareham, Nicholas;
    • Ahmed, Shahana;
    • Healey, Catherine S.;
    • Bowman, Richard;
    • Meyer, Kerstin B.;
    • Haiman, Christopher A.;
    • Kolonel, Laurence K.;
    • Henderson, Brian E.;
    • Le Marchand, Loic;
    • Brennan, Paul
    Publication type:
    Article
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    Barriers and Facilitators to Delivering Multifactorial Risk Assessment and Communication for Personalized Breast Cancer Screening: A Qualitative Study Exploring Implementation in Canada.

    Published in:
    Current Oncology, 2025, v. 32, n. 3, p. 155, doi. 10.3390/curroncol32030155
    By:
    • Walker, Meghan J.;
    • Neely, Anna;
    • Antoniou, Antonis C.;
    • Broeders, Mireille J. M.;
    • Brooks, Jennifer D.;
    • Carver, Tim;
    • Chiquette, Jocelyne;
    • Easton, Douglas F.;
    • Eisen, Andrea;
    • Eloy, Laurence;
    • Evans, D. Gareth R.;
    • Fienberg, Samantha;
    • Joly, Yann;
    • Kim, Raymond H.;
    • Knoppers, Bartha M.;
    • Lofters, Aisha K.;
    • Nabi, Hermann;
    • Pashayan, Nora;
    • Stockley, Tracy L.;
    • Dorval, Michel
    Publication type:
    Article
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    Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer.

    Published in:
    Nature Genetics, 2010, v. 42, n. 7, p. 604, doi. 10.1038/ng.607
    By:
    • Turnbull, Clare;
    • Rapley, Elizabeth A;
    • Seal, Sheila;
    • Pernet, David;
    • Renwick, Anthony;
    • Hughes, Deborah;
    • Ricketts, Michelle;
    • Linger, Rachel;
    • Nsengimana, Jeremie;
    • Deloukas, Panagiotis;
    • Collaboration, UK Testicular Cancer;
    • Huddart, Robert A;
    • Bishop, D Timothy;
    • Easton, Douglas F;
    • Stratton, Michael R;
    • Rahman, Nazneen
    Publication type:
    Article
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    A genome-wide association study of testicular germ cell tumor.

    Published in:
    Nature Genetics, 2009, v. 41, n. 7, p. 807, doi. 10.1038/ng.394
    By:
    • Rapley, Elizabeth A.;
    • Turnbull, Clare;
    • Al Olama, Ali Amin;
    • Dermitzakis, Emmanouil T.;
    • Linger, Rachel;
    • Huddart, Robert A.;
    • Renwick, Anthony;
    • Hughes, Deborah;
    • Hines, Sarah;
    • Seal, Sheila;
    • Morrison, Jonathan;
    • Nsengimana, Jeremie;
    • Deloukas, Panagiotis;
    • Rahman, Nazneen;
    • Bishop, D. Timothy;
    • Easton, Douglas F;
    • Stratton, Michael R.
    Publication type:
    Article
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    CORRESPONDENCE.

    Published in:
    2008
    By:
    • Eeles, Rosalinda;
    • Giles, Graham;
    • Neal, David;
    • Muir, Kenneth;
    • Easton, Douglas F.
    Publication type:
    Letter
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    PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene.

    Published in:
    Nature Genetics, 2007, v. 39, n. 2, p. 165, doi. 10.1038/ng1959
    By:
    • Rahman, Nazneen;
    • Seal, Sheila;
    • Thompson, Deborah;
    • Kelly, Patrick;
    • Renwick, Anthony;
    • Elliott, Anna;
    • Reid, Sarah;
    • Spanova, Katarina;
    • Barfoot, Rita;
    • Chagtai, Tasnim;
    • Jayatilake, Hiran;
    • McGuffog, Lesley;
    • Hanks, Sandra;
    • Evans, D. Gareth;
    • Eccles, Diana;
    • Easton, Douglas F.;
    • Stratton, Michael R.
    Publication type:
    Article
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    ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles.

    Published in:
    Nature Genetics, 2006, v. 38, n. 8, p. 873, doi. 10.1038/ng1837
    By:
    • Renwick, Anthony;
    • Thompson, Deborah;
    • Seal, Sheila;
    • Kelly, Patrick;
    • Chagtai, Tasnim;
    • Ahmed, Munaza;
    • North, Bernard;
    • Jayatilake, Hiran;
    • Barfoot, Rita;
    • Spanova, Katarina;
    • McGuffog, Lesley;
    • Evans, D. Gareth;
    • Eccles, Diana;
    • Easton, Douglas F.;
    • Stratton, Michael R.;
    • Rahman, Nazneen
    Publication type:
    Article
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    Low-penetrance susceptibility to breast cancer due to CHEK2<sup>*</sup>1100delC in noncarriers of BRCA1 or BRCA2 mutations.

    Published in:
    Nature Genetics, 2002, v. 31, n. 1, p. 55
    By:
    • Meijers-Heijboer, Hanne;
    • van den Ouweland, Ans;
    • Klijn, Jan;
    • Wasielewski, Marijke;
    • de Snoo, Anja;
    • Oldenburg, Rogier;
    • Hollestelle, Antoinette;
    • Houben, Mark;
    • Crepin, Ellen;
    • van Veghel-Plandsoen, Monique;
    • Elstrodt, Fons;
    • van Duijn, Cornelia;
    • Bartels, Carina;
    • Meijers, Carel;
    • Schutte, Mieke;
    • McGuffog, Lesley;
    • Thompson, Deborah;
    • Easton, Douglas F.;
    • Sodha, Nayanta
    Publication type:
    Article
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    Comprehensive Functional Annotation of 77 Prostate Cancer Risk Loci.

    Published in:
    PLoS Genetics, 2014, v. 10, n. 1, p. 1, doi. 10.1371/journal.pgen.1004102
    By:
    • Hazelett, Dennis J.;
    • Rhie, Suhn Kyong;
    • Gaddis, Malaina;
    • Yan, Chunli;
    • Lakeland, Daniel L.;
    • Coetzee, Simon G.;
    • Henderson, Brian E.;
    • Noushmehr, Houtan;
    • Cozen, Wendy;
    • Kote-Jarai, Zsofia;
    • Eeles, Rosalind A.;
    • Easton, Douglas F.;
    • Haiman, Christopher A.;
    • Lu, Wange;
    • Farnham, Peggy J.;
    • Coetzee, Gerhard A.
    Publication type:
    Article
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    Association between Adult Height and Risk of Colorectal, Lung, and Prostate Cancer: Results from Meta-analyses of Prospective Studies and Mendelian Randomization Analyses.

    Published in:
    2016
    By:
    • Khankari, Nikhil K.;
    • Shu, Xiao-Ou;
    • Wen, Wanqing;
    • Kraft, Peter;
    • Lindström, Sara;
    • Peters, Ulrike;
    • Schildkraut, Joellen;
    • Schumacher, Fredrick;
    • Bofetta, Paolo;
    • Risch, Angela;
    • Bickeböller, Heike;
    • Amos, Christopher I.;
    • Easton, Douglas;
    • Eeles, Rosalind A.;
    • Gruber, Stephen B.;
    • Haiman, Christopher A.;
    • Hunter, David J.;
    • Chanock, Stephen J.;
    • Pierce, Brandon L.;
    • Zheng, Wei
    Publication type:
    journal article
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    Should Age-Dependent Absolute Risk Thresholds Be Used for Risk Stratification in Risk-Stratified Breast Cancer Screening?

    Published in:
    Journal of Personalized Medicine, 2021, v. 11, n. 9, p. 916, doi. 10.3390/jpm11090916
    By:
    • Pashayan, Nora;
    • Antoniou, Antonis C.;
    • Lee, Andrew;
    • Wolfson, Michael;
    • Chiquette, Jocelyne;
    • Eloy, Laurence;
    • Eisen, Andrea;
    • Stockley, Tracy L.;
    • Nabi, Hermann;
    • Brooks, Jennifer D.;
    • Dorval, Michel;
    • Easton, Douglas F.;
    • Knoppers, Bartha Maria;
    • Chiarelli, Anna M.;
    • Simard, Jacques
    Publication type:
    Article
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    Personalized Risk Assessment for Prevention and Early Detection of Breast Cancer: Integration and Implementation (PERSPECTIVE I&I).

    Published in:
    Journal of Personalized Medicine, 2021, v. 11, n. 6, p. 511, doi. 10.3390/jpm11060511
    By:
    • Brooks, Jennifer D.;
    • Nabi, Hermann H.;
    • Andrulis, Irene L.;
    • Antoniou, Antonis C.;
    • Chiquette, Jocelyne;
    • Després, Philippe;
    • Devilee, Peter;
    • Dorval, Michel;
    • Droit, Arnaud;
    • Easton, Douglas F.;
    • Eisen, Andrea;
    • Eloy, Laurence;
    • Fienberg, Samantha;
    • Goldgar, David;
    • Hahnen, Eric;
    • Joly, Yann;
    • Knoppers, Bartha Maria;
    • Lofters, Aisha;
    • Masson, Jean-Yves;
    • Mittmann, Nicole
    Publication type:
    Article
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    Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue.

    Published in:
    Nature Genetics, 2015, v. 47, n. 4, p. 367, doi. 10.1038/ng.3221
    By:
    • Cooper, Colin S;
    • Clark, Jeremy;
    • Hurst, Rachel;
    • Mithen, Richard;
    • Bristow, Robert G;
    • Boutros, Paul C;
    • Fraser, Michael;
    • Greenman, Christopher;
    • Berney, Dan;
    • Voet, Thierry;
    • Easton, Douglas;
    • Warren, Anne Y;
    • Eeles, Rosalind;
    • Foster, Christopher S;
    • Brewer, Daniel S;
    • Neal, David E;
    • Wedge, David C;
    • Gundem, Gunes;
    • Alexandrov, Ludmil B;
    • Kremeyer, Barbara
    Publication type:
    Article
    40

    A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer.

    Published in:
    Nature Genetics, 2014, v. 46, n. 10, p. 1103, doi. 10.1038/ng.3094
    By:
    • Al Olama, Ali Amin;
    • Easton, Douglas F;
    • Kolonel, Laurence N;
    • Le Marchand, Loic;
    • Tammela, Teuvo L J;
    • Auvinen, Anssi;
    • Wahlfors, Tiina;
    • Schleutker, Johanna;
    • Visakorpi, Tapio;
    • Leinonen, Katri A;
    • Xu, Jianfeng;
    • Zheng, S Lilly;
    • Aly, Markus;
    • Donovan, Jenny;
    • Travis, Ruth C;
    • Key, Tim J;
    • Kote-Jarai, Zsofia;
    • Siddiq, Afshan;
    • Canzian, Federico;
    • Khaw, Kay-Tee
    Publication type:
    Article
    41

    Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14.

    Published in:
    Nature Genetics, 2013, v. 45, n. 6, p. 686, doi. 10.1038/ng.2635
    By:
    • Ruark, Elise;
    • Seal, Sheila;
    • McDonald, Heather;
    • Zhang, Feng;
    • Elliot, Anna;
    • Lau, KingWai;
    • Perdeaux, Elizabeth;
    • Rapley, Elizabeth;
    • Eeles, Rosalind;
    • Peto, Julian;
    • Kote-Jarai, Zsofia;
    • Muir, Kenneth;
    • Nsengimana, Jeremie;
    • Shipley, Janet;
    • Bishop, D Timothy;
    • Stratton, Michael R;
    • Easton, Douglas F;
    • Huddart, Robert A;
    • Rahman, Nazneen;
    • Turnbull, Clare
    Publication type:
    Article
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    Contralateral breast cancer risk in patients with breast cancer and a germline-BRCA1/2 pathogenic variant undergoing radiation.

    Published in:
    JNCI: Journal of the National Cancer Institute, 2023, v. 115, n. 11, p. 1318, doi. 10.1093/jnci/djad116
    By:
    • Barele, Mark van;
    • Akdeniz, Delal;
    • Heemskerk-Gerritsen, Bernadette A M;
    • Genepso;
    • Andrieu, Nadine;
    • Noguès, Catherine;
    • HEBON;
    • Asperen, Christi J van;
    • Wevers, Marijke;
    • Ausems, Margreet G E M;
    • Bock, Geertruida H de;
    • Dommering, Charlotte J;
    • Gómez-García, Encarnacion B;
    • Leeuwen, Flora E van;
    • Mooij, Thea M;
    • EMBRACE;
    • Easton, Douglas F;
    • Antoniou, Antonis C;
    • Evans, D Gareth;
    • Izatt, Louise
    Publication type:
    Article
    44

    Prediction of breast cancer risk for sisters of women attending screening.

    Published in:
    JNCI: Journal of the National Cancer Institute, 2023, v. 115, n. 11, p. 1310, doi. 10.1093/jnci/djad101
    By:
    • Mao, Xinhe;
    • He, Wei;
    • Eriksson, Mikael;
    • Lindström, Linda S;
    • Holowko, Natalie;
    • Bajalica-Lagercrantz, Svetlana;
    • Hammarström, Mattias;
    • Grassmann, Felix;
    • Humphreys, Keith;
    • Easton, Douglas;
    • Hall, Per;
    • Czene, Kamila
    Publication type:
    Article
    45

    Oral Contraceptive Use in BRCA1 and BRCA2 Mutation Carriers: Absolute Cancer Risks and Benefits.

    Published in:
    2022
    By:
    • Schrijver, Lieske H;
    • Mooij, Thea M;
    • Pijpe, Anouk;
    • Sonke, Gabe S;
    • Mourits, Marian J E;
    • Andrieu, Nadine;
    • Antoniou, Antonis C;
    • Easton, Douglas F;
    • Engel, Christoph;
    • Goldgar, David;
    • John, Esther M;
    • Kast, Karin;
    • Milne, Roger L;
    • Olsson, Håkan;
    • Phillips, Kelly-Anne;
    • Terry, Mary Beth;
    • Hopper, John L;
    • Leeuwen, Flora E van;
    • Rookus, Matti A;
    • van Leeuwen, Flora E
    Publication type:
    journal article
    46

    CHEK2, MGMT, SULT1E1 and SULT1A1 polymorphisms and endometrial cancer risk.

    Published in:
    2011
    By:
    • O'Mara, Tracy A;
    • Ferguson, Kaltin;
    • Fahey, Paul;
    • Marquart, Louise;
    • Yang, Hannah P;
    • Lissowska, Jolanta;
    • Chanock, Stephen;
    • Garcia-Closas, Montserrat;
    • Thompson, Deborah J;
    • Healey, Catherine S;
    • Dunning, Alison M;
    • Easton, Douglas F;
    • Webb, Penelope M;
    • Spurdle, Amanda B;
    • ANECS
    Publication type:
    journal article
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    Prospective evaluation of a breast-cancer risk model integrating classical risk factors and polygenic risk in 15 cohorts from six countries.

    Published in:
    2021
    By:
    • Hurson, Amber N;
    • Choudhury, Parichoy Pal;
    • Gao, Chi;
    • Hüsing, Anika;
    • Eriksson, Mikael;
    • Shi, Min;
    • Jones, Michael E;
    • Evans, D Gareth R;
    • Milne, Roger L;
    • Gaudet, Mia M;
    • Vachon, Celine M;
    • Chasman, Daniel I;
    • Easton, Douglas F;
    • Schmidt, Marjanka K;
    • Kraft, Peter;
    • Garcia-Closas, Montserrat;
    • Chatterjee, Nilanjan;
    • Group, for the B-CAST Risk Modelling;
    • Pal Choudhury, Parichoy;
    • B-CAST Risk Modelling Group
    Publication type:
    journal article
    49

    A Mendelian randomization analysis of circulating lipid traits and breast cancer risk.

    Published in:
    2020
    By:
    • Beeghly-Fadiel, Alicia;
    • Khankari, Nikhil K;
    • Delahanty, Ryan J;
    • Shu, Xiao-Ou;
    • Lu, Yingchang;
    • Schmidt, Marjanka K;
    • Bolla, Manjeet K;
    • Michailidou, Kyriaki;
    • Wang, Qin;
    • Dennis, Joe;
    • Yannoukakos, Drakoulis;
    • Dunning, Alison M;
    • Pharoah, Paul D P;
    • Chenevix-Trench, Georgia;
    • Milne, Roger L;
    • Hunter, David J;
    • Per, Hall;
    • Kraft, Peter;
    • Simard, Jacques;
    • Easton, Douglas F
    Publication type:
    journal article
    50

    Assessment of interactions between 205 breast cancer susceptibility loci and 13 established risk factors in relation to breast cancer risk, in the Breast Cancer Association Consortium.

    Published in:
    2020
    By:
    • Kapoor, Pooja Middha;
    • Lindström, Sara;
    • Behrens, Sabine;
    • Wang, Xiaoliang;
    • Michailidou, Kyriaki;
    • Bolla, Manjeet K;
    • Wang, Qin;
    • Dennis, Joe;
    • Dunning, Alison M;
    • Pharoah, Paul D P;
    • Schmidt, Marjanka K;
    • Kraft, Peter;
    • García-Closas, Montserrat;
    • Easton, Douglas F;
    • Milne, Roger L;
    • Chang-Claude, Jenny;
    • Consortium, on behalf of Breast Cancer Association;
    • Breast Cancer Association Consortium
    Publication type:
    journal article