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TREM2<sup>+</sup> and interstitial-like macrophages orchestrate airway inflammation in SARS-CoV-2 infection in rhesus macaques.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37425-9
By:
- Upadhyay, Amit A.;
- Viox, Elise G.;
- Hoang, Timothy N.;
- Boddapati, Arun K.;
- Pino, Maria;
- Lee, Michelle Y.-H.;
- Corry, Jacqueline;
- Strongin, Zachary;
- Cowan, David A.;
- Beagle, Elizabeth N.;
- Horton, Tristan R.;
- Hamilton, Sydney;
- Aoued, Hadj;
- Harper, Justin L.;
- Edwards, Christopher T.;
- Nguyen, Kevin;
- Pellegrini, Kathryn L.;
- Tharp, Gregory K.;
- Piantadosi, Anne;
- Levit, Rebecca D.
Publication type:
Article
Intradermal but not intramuscular modified vaccinia Ankara immunizations protect against intravaginal tier2 simian-human immunodeficiency virus challenges in female macaques.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40430-7
By:
- Bollimpelli, Venkata S.;
- Reddy, Pradeep B. J;
- Gangadhara, Sailaja;
- Charles, Tysheena P.;
- Burton, Samantha L.;
- Tharp, Gregory K.;
- Styles, Tiffany M.;
- Labranche, Celia C.;
- Smith, Justin C.;
- Upadhyay, Amit A.;
- Sahoo, Anusmita;
- Legere, Traci;
- Shiferaw, Ayalnesh;
- Velu, Vijayakumar;
- Yu, Tianwei;
- Tomai, Mark;
- Vasilakos, John;
- Kasturi, Sudhir P.;
- Shaw, George M.;
- Montefiori, David
Publication type:
Article
Tissue-specific transcriptional profiling of plasmacytoid dendritic cells reveals a hyperactivated state in chronic SIV infection.
Published in:
PLoS Pathogens, 2021, v. 17, n. 6, p. 1, doi. 10.1371/journal.ppat.1009674
By:
- Lee, Michelle Y.-H.;
- Upadhyay, Amit A.;
- Walum, Hasse;
- Chan, Chi N.;
- Dawoud, Reem A.;
- Grech, Christine;
- Harper, Justin L.;
- Karunakaran, Kirti A.;
- Nelson, Sydney A.;
- Mahar, Ernestine A.;
- Goss, Kyndal L.;
- Carnathan, Diane G.;
- Cervasi, Barbara;
- Gill, Kiran;
- Tharp, Gregory K.;
- Wonderlich, Elizabeth R.;
- Velu, Vijayakumar;
- Barratt-Boyes, Simon M.;
- Paiardini, Mirko;
- Silvestri, Guido
Publication type:
Article
Type I IFN signaling blockade by a PASylated antagonist during chronic SIV infection suppresses specific inflammatory pathways but does not alter T cell activation or virus replication.
Published in:
PLoS Pathogens, 2018, v. 14, n. 8, p. 1, doi. 10.1371/journal.ppat.1007246
By:
- Nganou-Makamdop, Krystelle;
- Billingsley, James M.;
- Yaffe, Zachary;
- O’Connor, Gregory;
- Tharp, Gregory K.;
- Ransier, Amy;
- Laboune, Farida;
- Matus-Nicodemos, Rodrigo;
- Lerner, Andrea;
- Gharu, Lavina;
- Robertson, Jennifer M.;
- Ford, Mandy L.;
- Schlapschy, Martin;
- Kuhn, Nadine;
- Lensch, Alexandra;
- Lifson, Jeffrey;
- Nason, Martha;
- Skerra, Arne;
- Schreiber, Gideon;
- Bosinger, Steven E.
Publication type:
Article
The Vacc-SeqQC project: Benchmarking RNA-Seq for clinical vaccine studies.
Published in:
Frontiers in Immunology, 2023, v. 13, p. 1, doi. 10.3389/fimmu.2022.1093242
By:
- Goll, Johannes B.;
- Bosinger, Steven E.;
- Jensen, Travis L.;
- Walum, Hasse;
- Grimes, Tyler;
- Tharp, Gregory K.;
- Natrajan, Muktha S.;
- Blazevic, Azra;
- Head, Richard D.;
- Gelber, Casey E.;
- Steenbergen, Kristen J.;
- Patel, Nirav B.;
- Sanz, Patrick;
- Rouphael, Nadine G.;
- Anderson, Evan J.;
- Mulligan, Mark J.;
- Hoft, Daniel F.
Publication type:
Article
Systems Analysis Reveals Contraceptive-Induced Alteration of Cervicovaginal Gene Expression in a Randomized Trial.
Published in:
Frontiers in Reproductive Health, 2022, v. 4, p. 1, doi. 10.3389/frph.2022.781687
By:
- Balle, Christina;
- Gupta, Prachi M.;
- Tharp, Gregory K.;
- Nelson, Sydney A.;
- Konstantinus, Iyaloo N.;
- Lennard, Katie;
- Jaumdally, Shameem Z.;
- Happel, Anna-Ursula;
- Barnabas, Shaun L.;
- Gill, Katherine;
- Bekker, Linda-Gail;
- Passmore, Jo-Ann S.;
- Jaspan, Heather B.;
- Bosinger, Steven E.
Publication type:
Article
Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques.
Published in:
Science Immunology, 2023, v. 8, n. 85, p. 1, doi. 10.1126/sciimmunol.adg0033
By:
- Viox, Elise G.;
- Hoang, Timothy N.;
- Upadhyay, Amit A.;
- Nchioua, Rayhane;
- Hirschenberger, Maximilian;
- Strongin, Zachary;
- Tharp, Gregory K.;
- Pino, Maria;
- Nguyen, Kevin;
- Harper, Justin L.;
- Gagne, Matthew;
- Marciano, Shir;
- Boddapati, Arun K.;
- Pellegrini, Kathryn L.;
- Pradhan, Arpan;
- Tisoncik-Go, Jennifer;
- Whitmore, Leanne S.;
- Karunakaran, Kirti A.;
- Roy, Melissa;
- Kirejczyk, Shannon
Publication type:
Article
Transcriptome analysis of GVHD reveals aurora kinase A as a targetable pathway for disease prevention.
Published in:
Science Translational Medicine, 2015, v. 7, n. 315, p. 1, doi. 10.1126/scitranslmed.aad3231
By:
- Furlan, Scott N.;
- Watkins, Benjamin;
- Tkachev, Victor;
- Flynn, Ryan;
- Cooley, Sarah;
- Ramakrishnan, Swetha;
- Singh, Karnail;
- Giver, Cindy;
- Hamby, Kelly;
- Stempora, Linda;
- Garrett, Aneesah;
- Jingyang Chen;
- Betz, Kayla M.;
- Ziegler, Carly G. K.;
- Tharp, Gregory K.;
- Bosinger, Steven E.;
- Promislow, Daniel E. L.;
- Miller, Jeffrey S.;
- Waller, Edmund K.;
- Blazar, Bruce R.
Publication type:
Article
Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression.
Published in:
Nature, 2014, v. 511, n. 7511, p. 601, doi. 10.1038/nature13554
By:
- Sandler, Netanya G.;
- Bosinger, Steven E.;
- Estes, Jacob D.;
- Zhu, Richard T. R.;
- Tharp, Gregory K.;
- Boritz, Eli;
- Levin, Doron;
- Wijeyesinghe, Sathi;
- Makamdop, Krystelle Nganou;
- del Prete, Gregory Q.;
- Hill, Brenna J.;
- Timmer, J. Katherina;
- Reiss, Emma;
- Yarden, Ganit;
- Darko, Samuel;
- Contijoch, Eduardo;
- Todd, John Paul;
- Silvestri, Guido;
- Nason, Martha;
- Norgren Jr, Robert B.
Publication type:
Article
A new rhesus macaque assembly and annotation for next-generation sequencing analyses.
Published in:
Biology Direct, 2014, v. 9, n. 1, p. 20, doi. 10.1186/1745-6150-9-20
By:
- Zimin, Aleksey V.;
- Cornish, Adam S.;
- Maudhoo, Mnirnal D.;
- Gibbs, Robert M.;
- Xiongfei Zhang;
- Pandey, Sanjit;
- Meehan, Daniel T.;
- Wipfler, Kristin;
- Bosinger, Steven E.;
- Johnson, Zachary P.;
- Tharp, Gregory K.;
- Marçais, Guillaume;
- Roberts, Michael;
- Ferguson, Betsy;
- Fox, Howard S.;
- Treangen, Todd;
- Salzberg, Steven L.;
- Yorke, James A.;
- Norgren Jr, Robert B.
Publication type:
Article
Progestin‐based contraception regimens modulate expression of putative HIV risk factors in the vaginal epithelium of pig‐tailed Macaques.
Published in:
American Journal of Reproductive Immunology, 2018, v. 80, n. 4, p. 1, doi. 10.1111/aji.13029
By:
- Bosinger, Steven E.;
- Tharp, Gregory K.;
- Patel, Nirav B.;
- Zhao, Chunxia;
- Payne, Tamika L.;
- Dietz Ostergaard, Sharon;
- Butler, Katherine;
- Ellis, Shanon;
- Johnson, Ryan L.;
- Kersh, Ellen N.;
- McNicholl, Janet M.;
- Vishwanathan, Sundaram A.
Publication type:
Article
Differences in Vaginal Microbiota, Host Transcriptome, and Proteins in Women With Bacterial Vaginosis Are Associated With Metronidazole Treatment Response.
Published in:
2021
By:
- Serebrenik, Joyce;
- Wang, Tao;
- Hunte, Richard;
- Srinivasan, Sujatha;
- McWalters, Jessica;
- Tharp, Gregory K;
- Bosinger, Steven E;
- Fiedler, Tina L;
- Atrio, Jessica M;
- Murphy, Kerry;
- Barnett, Rebecca;
- Ray, Laurie R;
- Krows, Meighan L;
- Fredricks, David N;
- Irungu, Elizabeth;
- Ngure, Kenneth;
- Mugo, Nelly;
- Marrazzo, Jeanne;
- Keller, Marla J;
- Herold, Betsy C
Publication type:
journal article
Innate, non-cytolytic CD8<sup>+</sup> T cell-mediated suppression of HIV replication by MHC-independent inhibition of virus transcription.
Published in:
PLoS Pathogens, 2020, v. 16, n. 9, p. 1, doi. 10.1371/journal.ppat.1008821
By:
- Zanoni, Michelle;
- Palesch, David;
- Pinacchio, Claudia;
- Statzu, Maura;
- Tharp, Gregory K.;
- Paiardini, Mirko;
- Chahroudi, Ann;
- Bosinger, Steven E.;
- Yoon, Jack;
- Cox, Bryan;
- Silvestri, Guido;
- Kulpa, Deanna A.
Publication type:
Article
BALDR: a computational pipeline for paired heavy and light chain immunoglobulin reconstruction in single-cell RNA-seq data.
Published in:
Genome Medicine, 2018, v. 10, p. 1, doi. 10.1186/s13073-018-0528-3
By:
- Upadhyay, Amit A.;
- Kauffman, Robert C.;
- Wolabaugh, Amber N.;
- Cho, Alice;
- Patel, Nirav B.;
- Reiss, Samantha M.;
- Havenar-Daughton, Colin;
- Dawoud, Reem A.;
- Tharp, Gregory K.;
- Sanz, Iñaki;
- Pulendran, Bali;
- Crotty, Shane;
- Lee, F. Eun-Hyung;
- Wrammert, Jens;
- Bosinger, Steven E.
Publication type:
Article
The role of CD101-expressing CD4 T cells in HIV/SIV pathogenesis and persistence.
Published in:
PLoS Pathogens, 2022, v. 18, n. 7, p. 1, doi. 10.1371/journal.ppat.1010723
By:
- Strongin, Zachary;
- Hoang, Timothy N.;
- Tharp, Gregory K.;
- Rahmberg, Andrew R.;
- Harper, Justin L.;
- Nguyen, Kevin;
- Franchitti, Lavinia;
- Cervasi, Barbara;
- Lee, Max;
- Zhang, Zhan;
- Boritz, Eli A.;
- Silvestri, Guido;
- Marconi, Vincent C.;
- Bosinger, Steven E.;
- Brenchley, Jason M.;
- Kulpa, Deanna A.;
- Paiardini, Mirko
Publication type:
Article

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