Works matching DE "LYSINE specific demethylase 1"

Results: 77

RSV‐Induced Regulation of DC via H3K4 Demethylase KDM5b.

Published in:

European Journal of Immunology, 2025, v. 55, n. 5, p. 1, doi. 10.1002/eji.202451309

By:

Mire, Mohamed M.;
Martinez, Llilian A.;
Cortes, Ashley M.;
Morris, Susan;
Rasky, Andrew;
Ptaschinski, Catherine;
Lukacs, Nicholas W.

Publication type:

Article

HFIP‐Promoted de Novo Synthesis of Biologically Relevant Nonnatural α‐Arylated Amino Esters and Dipeptide Mimetics.

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 72, p. 16528, doi. 10.1002/chem.201904395

By:

Li, Zhonghua;
Yu, Bin

Publication type:

Article

Lysine-Specific Demethylase 1-Selective Inactivators: Protein-Targeted Drug Delivery Mechanism.

Published in:

Angewandte Chemie, 2013, v. 125, n. 33, p. 8782, doi. 10.1002/ange.201303999

By:

Ogasawara, Daisuke;
Itoh, Yukihiro;
Tsumoto, Hiroki;
Kakizawa, Taeko;
Mino, Koshiki;
Fukuhara, Kiyoshi;
Nakagawa, Hidehiko;
Hasegawa, Makoto;
Sasaki, Ryuzo;
Mizukami, Tamio;
Miyata, Naoki;
Suzuki, Takayoshi

Publication type:

Article

Repression of LSD1/KDM1A activity improves the response of liver cancer cells to the lenvatinib.

Published in:

Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-024-00947-9

By:

Zong, Yi;
Tao, Zhigang;
Jiang, Siyi;
Wang, Minyuan;
Yu, Weihua

Publication type:

Article

LSD1 induces H3 K9 demethylation to promote adipogenesis in thyroid-associated ophthalmopathy.

Published in:

Epigenetics & Chromatin, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13072-025-00586-6

By:

Xu, Yuyan;
Hu, Jing;
Fan, Yuhang;
Sun, Licheng;
Shen, Ning;
Jin, Qihuang;
Zhang, Ling;
Zhang, Jin;
Zhang, Fang;
Chen, Hui

Publication type:

Article

CBB1003, a lysine-specific demethylase 1 inhibitor, suppresses colorectal cancer cells growth through down-regulation of leucine-rich repeat-containing G-protein-coupled receptor 5 expression.

Published in:

Journal of Cancer Research & Clinical Oncology, 2015, v. 141, n. 1, p. 11, doi. 10.1007/s00432-014-1782-4

By:

Hsu, Hung-Chih;
Liu, Yi-Shiuan;
Tseng, Kai-Chi;
Yang, Tsai-Sheng;
Yeh, Chien-Yuh;
You, Jeng-Fu;
Hung, Hsin-Yuan;
Chen, Shu-Jen;
Chen, Hua-Chien

Publication type:

Article

中低强度运动干预高脂饲养小鼠膝关节损伤软骨细胞 LncRNA HOTAIR 的表达.

Published in:

Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu, 2024, v. 28, n. 11, p. 1684, doi. 10.12307/2024.221

By:

张慧珍;
吴伟;
罗海涛

Publication type:

Article

KDM2 Family Members are Regulated by HIF-1 in Hypoxia.

Published in:

Cells (2073-4409), 2017, v. 6, n. 1, p. 8, doi. 10.3390/cells6010008

By:

Batie, Michael;
Druker, Jimena;
D'Ignazio, Laura;
Rocha, Sonia

Publication type:

Article

Lysine-Specific Demethylase 1A as a Promising Target in Acute Myeloid Leukemia.

Published in:

Frontiers in Oncology, 2018, p. 1, doi. 10.3389/fonc.2018.00255

By:

Magliulo, Daniela;
Bernardi, Rosa;
Messina, Samantha

Publication type:

Article

Crosstalk between lysine-specific demethylase 1 (LSD1) and histone deacetylases mediates antineoplastic efficacy of HDAC inhibitors in human breast cancer cells.

Published in:

Carcinogenesis, 2013, v. 34, n. 6, p. 1196, doi. 10.1093/carcin/bgt033

By:

Vasilatos, Shauna N.;
Katz, Tiffany A.;
Oesterreich, Steffi;
Wan, Yong;
Davidson, Nancy E.;
Huang, Yi

Publication type:

Article

Histone demethylase Lsd1 is required for the differentiation of neural cells in Nematostella vectensis.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28107-z

By:

Gahan, James M.;
Kouzel, Ian U.;
Jansen, Kamilla Ormevik;
Burkhardt, Pawel;
Rentzsch, Fabian

Publication type:

Article

CoREST1 Promotes Tumor Formation and Tumor Stroma Interactions in a Mouse Model of Breast Cancer.

Published in:

PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0121281

By:

Mazumdar, Sohini;
Arendt, Lisa M.;
Phillips, Sarah;
Sedic, Maja;
Kuperwasser, Charlotte;
Gill, Grace

Publication type:

Article

Lysine-Specific Demethylase 1 (LSD1/KDM1A) Contributes to Colorectal Tumorigenesis via Activation of the Wnt/Β-Catenin Pathway by Down-Regulating Dickkopf-1 (DKK1).

Published in:

PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0070077

By:

Huang, Zebin;
Li, Shangze;
Song, Wei;
Li, Xin;
Li, Qinshan;
Zhang, Zeyan;
Han, Yongqing;
Zhang, Xiaodong;
Miao, Shiying;
Du, Runlei;
Wang, Linfang

Publication type:

Article

Lysine-Specific Demethylase 1 in Breast Cancer Cells Contributes to the Production of Endogenous Formaldehyde in the Metastatic Bone Cancer Pain Model of Rats.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0058957

By:

Liu, Jia;
Liu, Feng-Yu;
Tong, Zhi-Qian;
Li, Zhi-Hua;
Chen, Wen;
Luo, Wen-Hong;
Li, Hui;
Luo, Hong-Jun;
Tang, Yan;
Tang, Jun-Min;
Cai, Jie;
Liao, Fei-Fei;
Wan, You

Publication type:

Article

Over-Expression of LSD1 Promotes Proliferation, Migration and Invasion in Non-Small Cell Lung Cancer.

Published in:

PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0035065

By:

Tangfeng Lv;
Dongmei Yuan;
Xiaohui Miao;
Yanling Lv;
Ping Zhan;
Xiaokun Shen;
Yong Song

Publication type:

Article

AACR Meeting Highlights New Findings on Drug Resistance, Targeted Therapies.

Published in:

Cancer (0008543X), 2013, v. 119, n. 18, p. 3259, doi. 10.1002/cncr.28337

By:

Printz, Carrie

Publication type:

Article

Identification of Novel Selective Lysine-Specific Demethylase 1 ( LSD1) Inhibitors Using a Pharmacophore-Based Virtual Screening Combined with Docking.

Published in:

2015

By:

Zhou, Chen;
Kang, Di;
Xu, Yungen;
Zhang, Luyong;
Zha, Xiaoming

Publication type:

Editorial

Physiological effects of KDM5C on neural crest migration and eye formation during vertebrate development.

Published in:

Epigenetics & Chromatin, 2018, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13072-018-0241-x

By:

Kim, Youni;
Jeong, Youngeun;
Kwon, Kujin;
Ismail, Tayaba;
Lee, Hyun-Kyung;
Kim, Chowon;
Park, Jeen-Woo;
Kwon, Oh-Shin;
Kang, Beom-Sik;
Lee, Dong-Seok;
Park, Tae Joo;
Kwon, Taejoon;
Lee, Hyun-Shik

Publication type:

Article

Mizl Controls Schwann Cell Proliferation via H3K36<sup>me2</sup> Demethylase Kdm8 to Prevent Peripheral Nerve Demyelination.

Published in:

Journal of Neuroscience, 2018, v. 38, n. 4, p. 858, doi. 10.1523/JNEUROSCI.0843-17.2017

By:

Fuhrmann, David;
Elsässer, Hans-Peter;
Nist, Andrea;
Mernberger, Marco;
Stiewe, Thorsten

Publication type:

Article

KDM1A genetic alterations, a rare cause of primary bilateral macronodular adrenal hyperplasia, strongly associated with food-dependent Cushing's syndrome: results of its systematic germline screening in 301 index cases and genotype/phenotype correlation.

Published in:

European Journal of Endocrinology, 2025, v. 192, n. 2, p. 119, doi. 10.1093/ejendo/lvaf016

By:

Bouys, Lucas;
Vaduva, Patricia;
Jouinot, Anne;
Violon, Florian;
Vaczlavik, Anna;
Barat, Maxime;
Charchar, Helaine;
Chasseloup, Fanny;
Kamilaris, Crystal;
Espiard, Stéphanie;
Haissaguerre, Magalie;
Raverot, Gérald;
Kroiss, Matthias;
Berthon, Annabel;
Perlemoine, Karine;
Tauveron, Igor;
Guignat, Laurence;
Libé, Rossella;
Groussin, Lionel;
Assié, Guillaume

Publication type:

Article

Regulation of tissue factor pathway inhibitor-2 (TFPI-2) expression by lysine-specific demethylase 1 and 2 (LSD1 and LSD2).

Published in:

Bioscience, Biotechnology & Biochemistry, 2014, v. 78, n. 6, p. 1010, doi. 10.1080/09168451.2014.910104

By:

Koshiki Mino;
Satoshi Nishimura;
Shogo Ninomiya;
Hiroshi Tujii;
Yasumasa Matsumori;
Mie Tsuchida;
Miho Hosoi;
Koichi Koseki;
Shuichi Wada;
Makoto Hasegawa;
Ryuzo Sasaki;
Yukie Murakami-Yamaguchi;
Hiroshi Narita;
Takayoshi Suzuki;
Naoki Miyata;
Tamio Mizukami

Publication type:

Article

Mutations in MurE, the essential UDP- N-acetylmuramoylalanyl- d-glutamate 2,6-diaminopimelate ligase of Corynebacterium glutamicum: effect on l-lysine formation and analysis of systemic consequences.

Published in:

Biotechnology Letters, 2017, v. 39, n. 2, p. 283, doi. 10.1007/s10529-016-2243-8

By:

Hochheim, Jennifer;
Kranz, Angela;
Krumbach, Karin;
Sokolowsky, Sascha;
Eggeling, Lothar;
Noack, Stephan;
Bocola, Marco;
Bott, Michael;
Marienhagen, Jan

Publication type:

Article

The Combined Effect of Retinoic Acid and LSD1 siRNA Inhibition on Cell Death in the Human Neuroblastoma Cell Line SH-SY5Y.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2013, v. 31, n. 6, p. 854, doi. 10.1159/000350103

By:

Xu, Guofeng;
Xiao, Yongtao;
Hu, Jimeng;
Xing, Lili;
Zhao, Ou;
Wu, Yeming

Publication type:

Article

Discovery of orally active chalcones as histone lysine specific demethylase 1 inhibitors for the treatment of leukaemia.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 207, doi. 10.1080/14756366.2020.1852556

By:

Li, Yang;
Sun, Ying;
Zhou, Yang;
Li, Xinyang;
Zhang, Huan;
Zhang, Guojun

Publication type:

Article

Combinatorial CRISPR screen reveals FYN and KDM4 as targets for synergistic drug combination for treating triple negative breast cancer.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.93921

By:

Tackhoon Kim;
Byung-Sun Park;
Soobeen Heo;
Jeon, Heeju;
Kim, Jaeyeal;
Donghwa Kim;
Sang Kook Lee;
So-Youn Jung;
Sun-Young Kong;
Timothy Lu

Publication type:

Article

LSD1 inhibition modulates transcription factor networks in myeloid malignancies.

Published in:

Frontiers in Oncology, 2023, v. 13, p. 1, doi. 10.3389/fonc.2023.1149754

By:

Hartung, Emily E.;
Singh, Kanwaldeep;
Berg, Tobias

Publication type:

Article

Lysine specific demethylase 1 is a molecular driver and therapeutic target in sarcoma.

Published in:

Frontiers in Oncology, 2023, v. 12, p. 1, doi. 10.3389/fonc.2022.1076581

By:

Dreher, Rachel D.;
Theisen, Emily R.

Publication type:

Article

LSD1n is an H4K20 demethylase regulating memory formation via transcriptional elongation control.

Published in:

Nature Neuroscience, 2015, v. 18, n. 9, p. 1256, doi. 10.1038/nn.4069

By:

Wang, Jianxun;
Telese, Francesca;
Tan, Yuliang;
Li, Wenbo;
Jin, Chunyu;
He, Xin;
Basnet, Harihar;
Ma, Qi;
Merkurjev, Daria;
Zhu, Xiaoyan;
Liu, Zhijie;
Zhang, Jie;
Ohgi, Kenny;
Taylor, Havilah;
White, Ryan R;
Tazearslan, Cagdas;
Suh, Yousin;
Macfarlan, Todd S;
Pfaff, Samuel L;
Rosenfeld, Michael G

Publication type:

Article

KDM1A/LSD1 regulates the differentiation and maintenance of spermatogonia in mice.

Published in:

PLoS ONE, 2017, v. 12, n. 5, p. 1, doi. 10.1371/journal.pone.0177473

By:

Myrick, Dexter A.;
Christopher, Michael A.;
Scott, Alyssa M.;
Simon, Ashley K.;
Donlin-Asp, Paul G.;
Kelly, William G.;
Katz, David J.

Publication type:

Article

Structure activity relationship and modeling studies of inhibitors of lysine specific demethylase 1.

Published in:

PLoS ONE, 2017, v. 12, n. 2, p. 1, doi. 10.1371/journal.pone.0170301

By:

Zhou, Chao;
Wu, Fangrui;
Lu, Lianghao;
Wei, Liping;
Pai, Eric;
Yao, Yuan;
Song, Yongcheng

Publication type:

Article

Positive Expression of LSD1 and Negative Expression of E-cadherin Correlate with Metastasis and Poor Prognosis of Colon Cancer.

Published in:

Digestive Diseases & Sciences, 2013, v. 58, n. 6, p. 1581, doi. 10.1007/s10620-012-2552-2

By:

Jie, Ding;
Zhongmin, Zhang;
Guoqing, Liao;
Sheng, Liu;
Yi, Zhang;
Jing, Wen;
Liang, Zeng

Publication type:

Article

Correction: Histone demethylase LSD1 restricts influenza A virus infection by erasing IFITM3-K88 monomethylation.

Published in:

2018

By:

Shan, Jiaoyu;
Zhao, Binbin;
Shan, Zhao;
Nie, Jia;
Deng, Rong;
Xiong, Rui;
Tsun, Andy;
Pan, Weiqi;
Zhao, Hanzhi;
Chen, Ling;
Jin, Ying;
Qian, Zhikang;
Lui, Kawing;
Liang, Rui;
Li, Dan;
Sun, Bing;
Lavillette, Dimitri;
Xu, Ke;
Li, Bin

Publication type:

Correction Notice

LSD1 Regulates Pluripotency of Embryonic Stem/Carcinoma Cells through Histone Deacetylase 1-Mediated Deacetylation of Histone H4 at Lysine 16.

Published in:

Molecular & Cellular Biology, 2014, v. 34, n. 2, p. 158, doi. 10.1128/MCB.00631-13

By:

Feng Yin;
Rongfeng Lan;
Xiaoming Zhang;
Linyu Zhu;
Fangfang Chen;
Zhengshuang Xu;
Yuqing Liu;
Tao Ye;
Hong Sun;
Fei Lu;
Hui Zhang

Publication type:

Article

Recognition of CpG Island Chromatin by KDM2A Requires Direct and Specific Interaction with Linker DNA.

Published in:

Molecular & Cellular Biology, 2012, v. 32, n. 2, p. 18, doi. 10.1128/MCB.06332-11

By:

Zhou, Jin C.;
Blackledge, Neil P.;
Farcas, Anca M.;
Klose, Robert J.

Publication type:

Article

ORY‐1001, a KDM1A inhibitor, inhibits proliferation, and promotes apoptosis of triple negative breast cancer cells by inactivating androgen receptor.

Published in:

Drug Development Research, 2022, v. 83, n. 1, p. 208, doi. 10.1002/ddr.21860

By:

Wang, Tian;
Zhang, Fulin;
Sun, Fulan

Publication type:

Article

Drug Design Concepts for LSD1‐Selective Inhibitors.

Published in:

Chemical Record, 2018, v. 18, n. 12, p. 1782, doi. 10.1002/tcr.201810031

By:

Ota, Yosuke;
Suzuki, Takayoshi

Publication type:

Article

Cancer: Targeting LSD1 in small cell lung cancer.

Published in:

Nature Reviews Drug Discovery, 2015, v. 14, n. 9, p. 602, doi. 10.1038/nrd4722

By:

Crunkhorn, Sarah

Publication type:

Article

Lysine specific demethylase 1 inhibits sodium arsenite activation of HSCs by regulating SESN2/AMPK/ULK1 signaling pathway activity.

Published in:

Environmental Toxicology, 2024, v. 39, n. 6, p. 3563, doi. 10.1002/tox.24184

By:

Zhang, Yingwan;
Tian, Tian;
Liang, Cai;
Wang, Junli;
Zhang, Jiayuan;
Tian, Shanshan;
Xie, Rujia;
Yang, Ting;
Han, Bing

Publication type:

Article

LSD1 Activates PI3K/AKT Signaling Through Regulating p85 Expression in Prostate Cancer Cells.

Published in:

Frontiers in Oncology, 2019, p. 1, doi. 10.3389/fonc.2019.00721

By:

Wang, Zifeng;
Gao, Shuai;
Han, Dong;
Han, Wanting;
Li, Muqing;
Cai, Changmeng

Publication type:

Article

Pharmacological inhibition of LSD1 for the treatment of MLL-rearranged leukemia.

Published in:

Journal of Hematology & Oncology, 2016, v. 9, p. 1, doi. 10.1186/s13045-016-0252-7

By:

Zizhen Feng;
Yuan Yao;
Chao Zhou;
Fengju Chen;
Fangrui Wu;
Liping Wei;
Wei Liu;
Shuo Dong;
Redell, Michele;
Qianxing Mo;
Yongcheng Song

Publication type:

Article

Nuclear import of human histone lysine-specific demethylase LSD1.

Published in:

Journal of Biochemistry, 2014, v. 156, n. 6, p. 305, doi. 10.1093/jb/mvu042

By:

Jin, Yanhua;
Kim, Tae Young;
Kim, Min Seong;
Kim, Min Aeh;
Park, Su Hyung;
Jang, Yeun Kyu

Publication type:

Article

ZF-CxxC domain-containing proteins, CpG islands and the chromatin connection.

Published in:

Biochemical Society Transactions, 2013, v. 41, n. 3, p. 727, doi. 10.1042/BST20130028

By:

Long, Hannah K.;
Blackledge, Neil P.;
Klose, Robert J.

Publication type:

Article

Machine-Learning-Enabled Virtual Screening for Inhibitors of Lysine-Specific Histone Demethylase 1.

Published in:

Molecules, 2021, v. 26, n. 24, p. 7492, doi. 10.3390/molecules26247492

By:

Zhou, Jiajun;
Wu, Shiying;
Lee, Boon Giin;
Chen, Tianwei;
He, Ziqi;
Lei, Yukun;
Tang, Bencan;
Hirst, Jonathan D.

Publication type:

Article

Investigating the Binding Mode of Reversible LSD1 Inhibitors Derived from Stilbene Derivatives by 3D-QSAR, Molecular Docking, and Molecular Dynamics Simulation.

Published in:

Molecules, 2019, v. 24, n. 24, p. 4479, doi. 10.3390/molecules24244479

By:

Xu, Yongtao;
He, Zihao;
Yang, Min;
Gao, Yunlong;
Jin, Linfeng;
Wang, Meiting;
Zheng, Yichao;
Lu, Xiaoyuan;
Zhang, Songjie;
Wang, Chang;
Zhao, Zongya;
Zhao, Junqiang;
Gao, Qinghe;
Duan, Yingchao;
González, Florenci V.

Publication type:

Article

Design, Synthesis and Biological Evaluation of Novel Osimertinib-Based HDAC and EGFR Dual Inhibitors.

Published in:

Molecules, 2019, v. 24, n. 13, p. 2407, doi. 10.3390/molecules24132407

By:

Dong, Hang;
Yin, Hao;
Zhao, Chunlong;
Cao, Jiangying;
Xu, Wenfang;
Zhang, Yingjie

Publication type:

Article

GFI1B and LSD1 repress myeloid traits during megakaryocyte differentiation.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06090-z

By:

Venhuizen, Jeron;
van Bergen, Maaike G. J. M.;
Bergevoet, Saskia M.;
Gilissen, Daan;
Spruijt, Cornelia G.;
Wingens, Laura;
van den Akker, Emile;
Vermeulen, Michiel;
Jansen, Joop H.;
Martens, Joost H. A.;
van der Reijden, Bert A.

Publication type:

Article

Sensory systems: Making a choice and sticking with it.

Published in:

Nature Reviews Neuroscience, 2013, v. 14, n. 9, p. 590, doi. 10.1038/nrn3572

By:

Whalley, Katherine

Publication type:

Article

Targeting Nuclear LSD1 to Reprogram Cancer Cells and Reinvigorate Exhausted T Cells via a Novel LSD1-EOMES Switch.

Published in:

Frontiers in Immunology, 2020, v. 11, p. 1, doi. 10.3389/fimmu.2020.01228

By:

Tu, Wen Juan;
McCuaig, Robert D.;
Tan, Abel H. Y.;
Hardy, Kristine;
Seddiki, Nabila;
Ali, Sayed;
Dahlstrom, Jane E.;
Bean, Elaine G.;
Dunn, Jenny;
Forwood, Jade;
Tsimbalyuk, Sofia;
Smith, Kate;
Yip, Desmond;
Malik, Laeeq;
Prasanna, Thiru;
Milburn, Peter;
Rao, Sudha

Publication type:

Article

KDM5A promotes proliferation and EMT in ovarian cancer and closely correlates with PTX resistance.

Published in:

Molecular Medicine Reports, 2017, v. 16, n. 3, p. 3573, doi. 10.3892/mmr.2017.6960

By:

TONGFU FENG;
YAN WANG;
YAN LANG;
YUANZHEN ZHANG

Publication type:

Article

Effects of cisplatin on the LSD1-mediated invasion and metastasis of prostate cancer cells.

Published in:

Molecular Medicine Reports, 2016, v. 14, n. 3, p. 2511, doi. 10.3892/mmr.2016.5571

By:

ZHI-YUAN CHEN;
HUI CHEN;
TAO QIU;
XIAO-DONG WENG;
JIA GUO;
LEI WANG;
XIU-HENG LIU

Publication type:

Article