Works matching DE "PROTEIN-tyrosine kinases"

Results: 5000

Case Report: ALK -rearranged mesenchymal neoplasms with S100 and CD34 co-expression: additional cases with distinct characteristics.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1516491

By:

Ouyang, Qi;
Guo, Xiaohong;
Mao, Rongjun;
Cao, Zhixing

Publication type:

Article

Integrated Bioinformatics and Docking Study on Phenolic Compounds for Targeting Hypoxia-Associated Genes in Preeclampsia.

Published in:

Tropical Journal of Natural Product Research, 2025, v. 9, n. 5, p. 2177, doi. 10.26538/tjnpr/v9i5.43

By:

Suryandari, Dwi A.;
Muharam, Raden;
Tedjo, Aryo;
Fadilah, Fadilah

Publication type:

Article

Cracking the Kinase Code: Urinary Biomarkers as Early Alarms for AAA Rupture—A Pilot Study.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 11, p. 3845, doi. 10.3390/jcm14113845

By:

Östling, Emma Maria;
Baltrunas, Tomas;
Grootenboer, Nathalie;
Urbonavicius, Sigitas

Publication type:

Article

Seasonal Proteomic Variations and Biomarkers in Seasonal Allergic Rhinitis: Insights from Olink Inflammation Profiling.

Published in:

Journal of Inflammation Research, 2025, v. 18, p. 6191, doi. 10.2147/JIR.S519126

By:

Shen, Jiaqi;
Zheng, Xinliang;
Yan, Mohan;
Feng, Minqian;
Ding, Chan;
Xie, Shuanghua;
Xu, Huadong

Publication type:

Article

A Novel Molecular Regulatory Network in Bone Marrow Mesenchymal Stem Cells for Age‐Related Osteoporosis.

Published in:

Clinical Endocrinology, 2025, v. 102, n. 6, p. 635, doi. 10.1111/cen.15239

By:

Gao, Ming‐Dong;
Wang, Xiao‐Jun;
Li, Peng‐Biao;
Dong, Qian‐Qian;
Tian, Li‐Min

Publication type:

Article

Inhibiting Pyk2/Src expression by miR-23b-3p suppressed liver cancer stem cell function and hepatic carcinoma progression.

Published in:

Cancer Cell International, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12935-025-03841-8

By:

Sha, Meng;
Zhang, Jiang;
Liu, Jin-kai;
Qu, Xiao-ye;
Shen, Chuan;
Tong, Ying;
Cao, Jie

Publication type:

Article

Disruption of Ephb1 causes reduced hypothalamic CRH and TRH expression and obesity in mice.

Published in:

Obesity (19307381), 2025, v. 33, n. 6, p. 1101, doi. 10.1002/oby.24275

By:

Xie, Simin;
Zhao, Tao;
Hu, Chengchen;
Meng, Yongyong;
Cui, Jing;
Wu, Xiaohui

Publication type:

Article

EPHA5 regulates antifungal innate immunity by phosphorylating EPHB2 and Dectin-1.

Published in:

PLoS Pathogens, 2025, v. 21, n. 6, p. 1, doi. 10.1371/journal.ppat.1013179

By:

Gao, Ru;
Wang, Heping;
Cui, Zhihui;
Du, Yanyun;
He, Ruirui;
Feng, Lingyun;
Zeng, Bo;
Li, Yangyang;
Huang, Guoling;
Pan, Ting;
Wang, Yuan;
Yi, Ming;
Wang, Chenhui

Publication type:

Article

Shared hub genes in membranous nephropathy and kidney renal clear cell carcinoma: investigating molecular overlap and tumor progression.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02701-1

By:

Hui, Peng;
Shuwen, Zhang

Publication type:

Article

Responsiveness of different MET tumour alterations to type I and type II MET inhibitors.

Published in:

Clinical & Translational Medicine, 2025, v. 15, n. 5, p. 1, doi. 10.1002/ctm2.70338

By:

Murciano‐Goroff, Yonina R.;
Foglizzo, Valentina;
Chang, Jason;
Rekhtman, Natasha;
Sisk, Ann Elizabeth;
Gibson, Jamie;
Judka, Lia;
Clemens, Kristen;
Roa, Paola;
Ahmed, Shaza Sayed;
Bremer, Nicole V.;
Binaco, Courtney Lynn;
Muzungu, Sherifah Kemigisha;
Rodriguez, Estelamari;
Merrill, Madeline;
Sgroe, Erica;
Repetto, Matteo;
Stadler, Zsofia K.;
Berger, Michael F.;
Yu, Helena A.

Publication type:

Article

Tofacitinib treatment for plaque psoriasis and psoriatic arthritis: A meta-analysis of randomised controlled trials.

Published in:

Indian Journal of Dermatology, Venereology & Leprology, 2025, v. 91, n. 2, p. 1, doi. 10.25259/IJDVL_14_2024

By:

Wang, Tao;
Wu, Wei;
Zhang, Xiaoqing;
Gan, Bin;
Zhou, Yanfang;
Cheng, Xiaoyan

Publication type:

Article

The Abelson kinase and the Nedd4 family E3 ligases co-regulate Notch trafficking to limit signaling.

Published in:

Journal of Cell Biology, 2025, v. 224, n. 6, p. 1, doi. 10.1083/jcb.202407066

By:

Miranda-Alban, Julio;
Sanchez-Luege, Nicelio;
Valbuena, Fernando M.;
Rangel, Chyan;
Rebay, Ilaria

Publication type:

Article

Genome-wide DNA methylation analysis of hippocampal tissue in a murine model of attention deficit-hyperactivity disorder.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0323756

By:

Vidal, Rodrigo;
Lopez, Ignacio;
Ugarte, Gonzalo;
Contreras, Darwin;
Piña, Ricardo;
Godoy, Felipe;
Rozas, Carlos;
Rubio, David;
Mantellero, Carola;
Constandil, Luis;
Escobar, Jorge;
Morales, Bernardo

Publication type:

Article

Characterization of c-Src During Listeria monocytogenes Cell-to-Cell Spreading Open Access.

Published in:

Journal of Infectious Diseases, 2025, v. 231, n. 5, p. e912, doi. 10.1093/infdis/jiaf063

By:

McLeod, Petra A;
Dhanda, Aaron S;
Guttman, Julian A

Publication type:

Article

The immunosuppressive effect of glucocorticoids in human primary T cells is mainly mediated via a rapid inhibition of the IL-2/IL-2R signaling axis.

Published in:

Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02266-0

By:

Albarracin Melo, L. Tatiana;
Abdulkhakov, Nekruz;
Han, Irina;
El-Bizri, Ali;
Brunner-Weinzierl, Monika;
Schraven, Burkhart;
Simeoni, Luca

Publication type:

Article

Genetic analysis of ERBB4 gene in Chinese patients with amyotrophic lateral sclerosis: a single-center study and systematic review of published literature.

Published in:

Frontiers in Aging Neuroscience, 2025, p. 1, doi. 10.3389/fnagi.2025.1584541

By:

Shen, Dongchao;
Yang, Xunzhe;
He, Di;
Zhang, Kang;
Liu, Shuangwu;
Sun, Xiaohan;
Li, Jinyue;
Cai, Zhengyi;
Liu, Mingsheng;
Zhang, Xue;
Liu, Qing;
Cui, Liying

Publication type:

Article

Oncotype DX Recurrence Score and Germline BRCA Variants in Patients with HR-Positive/HER2-Negative Early Breast Cancer: A Retrospective Observational Study.

Published in:

Oncology & Therapy, 2025, v. 13, n. 2, p. 363, doi. 10.1007/s40487-025-00332-8

By:

Morganti, Stefania;
Khan, Rabia A.;
Berrocal-Almanza, Luis C.;
Miranda, Miguel;
Luo, Linlin;
Xu, Xiaoqing;
Partridge, Ann H.;
Lynce, Filipa

Publication type:

Article

The Laxative Effect of Lactobacillus paracasei Glory LP16 in Mice.

Published in:

Journal of Chinese Institute of Food Science & Technology / Zhongguo Shipin Xuebao, 2025, v. 25, n. 3, p. 209, doi. 10.16429/j.1009-7848.2025.03.021

By:

SHI Xiaodan;
ZHANG Rui;
LI Bailiang

Publication type:

Article

The regulation and mechanism of the cAMP-PKA pathway on PTSD-like behaviors exacerbated by alcohol exposure.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1592187

By:

Zhao, Shuang;
Zhao, Wei;
Wang, Ziqi;
Chen, Xiaofei;
Zong, Fangjiao;
Zhang, Hanting

Publication type:

Article

Real-world treatment patterns and outcomes among patients with HER2-positive unresectable or metastatic breast cancer in China.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1527990

By:

Huang, Jiajia;
Chen, Limin;
Song, Lihua;
Tong, Zhongsheng;
Sun, Tao;
Wang, Xiaojia;
Liu, Yi;
Wang, Shusen

Publication type:

Article

Decoding the impact of glucose-dependent insulinotropic polypeptide receptor (GIPR) agonist on cardiometabolic health: inflammatory mediators at the focus.

Published in:

Diabetology & Metabolic Syndrome, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13098-025-01744-2

By:

Cheng, Fang;
Niu, Xinyu;
Wang, Yaoling;
Yang, Fan;
Yang, Kang;
Li, Wei

Publication type:

Article

Neurotrophic and Neurotoxic Effects of Aβ42 and Its Oligomers on Neuronal Survival: Revealed by Their Opposite Influence on the Potency of Extracellular BDNF.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4501, doi. 10.3390/ijms26104501

By:

Li, He;
Zheng, Changxin;
Wen, Kai;
Zhang, Tianyu;
Zhang, Yingjiu

Publication type:

Article

Punicalagin ameliorates lipopolysaccharide-induced inflammatory response in dental pulp cells via inhibition of the NF-κB/Wnt5a-ROR2 pathway.

Published in:

Immunopharmacology & Immunotoxicology, 2025, v. 47, n. 3, p. 317, doi. 10.1080/08923973.2025.2470343

By:

Yang, Yumeng;
Deng, Ke;
Jiang, Shan;
Guo, Xiaolan;
Zhong, Yiming;
Wu, Buling;
Wei, Liu

Publication type:

Article

Use of Erlotinib or Gefitinib as Initial Therapy in Advanced NSCL.

Published in:

Oncology (08909091), 2010, v. 24, n. 5, p. 392

By:

Oxnard, Geofrey R.;
Miller, Vincent A.

Publication type:

Article

Management of Patients With Resistant or Refractory Chronic Myelogenous Leukemia.

Published in:

Oncology (08909091), 2008, v. 22, n. 4, p. 430

By:

Quintás-Cardama, Alfonso;
Cortes, Jorge

Publication type:

Article

Building on the Foundation of 5-FU to Treat Metastatic Colorectal Cancer.

Published in:

Oncology (08909091), 2008, v. 22, n. 4, p. 462

By:

Eng, Cathy

Publication type:

Article

When Imatinib Fails.

Published in:

Oncology (08909091), 2008, v. 22, n. 4, p. 448

By:

Stone, Richard

Publication type:

Article

Second-Generation TKIs in Chronic Myelogenous Leukemia.

Published in:

Oncology (08909091), 2008, v. 22, n. 4, p. 446

By:

Schiffer, Charles A.

Publication type:

Article

Refractory CML: Not All Forms of Resistance Are Equal.

Published in:

Oncology (08909091), 2008, v. 22, n. 4, p. 437

By:

DeVetten, Marcel

Publication type:

Article

Is Guillain Barré Syndrome Likely in This Patient?

Published in:

Oncology (08909091), 2008, v. 22, n. 1, p. 70

By:

Rini, Brian I.;
Shook, Steven

Publication type:

Article

Guillain-Barré Syndrome After Treatment With Sunitinib Malate?

Published in:

Oncology (08909091), 2008, v. 22, n. 1, p. 66

By:

Mulherin, Brian;
Loconte, Noelle K.;
Holen, Kyle D.

Publication type:

Article

Drug Essentials.

Published in:

Oncology (08909091), 2007, v. 21, p. 48

By:

Wilkes, Gail

Publication type:

Article

The Saba/Khuri/Shin Article Reviewed.

Published in:

Oncology (08909091), 2006, v. 20, n. 2, p. 172

By:

Gibson, Michael K.

Publication type:

Article

Targeting the Epidermal Growth Factor Receptor.

Published in:

Oncology (08909091), 2006, v. 20, n. 2, p. 153

By:

Saba, Nabil F.;
Khuri, Fadlo R.;
Shin, Dong M.

Publication type:

Article

Several different cytogenetic clones arising during treatment of Philadelphia positive chronic myeloid leukemia with tyrosine kinase inhibitors lead to the progression into Philadelphia negative acute myeloid leukemia.

Published in:

Vojnosanitetski Pregled: Military Medical & Pharmaceutical Journal of Serbia, 2021, v. 78, n. 1, p. 114, doi. 10.2298/VSP180723010D

By:

Denčić-Fekete, Marija;
Leković, Danijela;
Djordjević, Vesna;
Jovanović, Jelica;
Todorić-Živanović, Biljana;
Jaković, Ljubomir;
Bogdanović, Andrija

Publication type:

Article

Molecular basis for pseudokinase-dependent autoinhibition of JAK2 tyrosine kinase.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 7, p. 579, doi. 10.1038/nsmb.2849

By:

Shan, Yibing;
Gnanasambandan, Kavitha;
Ungureanu, Daniela;
Kim, Eric T;
Hammarén, Henrik;
Yamashita, Kazuo;
Silvennoinen, Olli;
Shaw, David E;
Hubbard, Stevan R

Publication type:

Article

Structural basis of recognition of interferon-α receptor by tyrosine kinase 2.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 5, p. 443, doi. 10.1038/nsmb.2807

By:

Wallweber, Heidi J A;
Tam, Christine;
Franke, Yvonne;
Starovasnik, Melissa A;
Lupardus, Patrick J

Publication type:

Article

Structurally encoded intraclass differences in EphA clusters drive distinct cell responses.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 8, p. 958, doi. 10.1038/nsmb.2617

By:

Seiradake, Elena;
Schaupp, Andreas;
del Toro Ruiz, Daniel;
Kaufmann, Rainer;
Mitakidis, Nikolaos;
Harlos, Karl;
Aricescu, A Radu;
Klein, Rüdiger;
Jones, E Yvonne

Publication type:

Article

Interaction with Shc prevents aberrant Erk activation in the absence of extracellular stimuli.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 5, p. 620, doi. 10.1038/nsmb.2557

By:

Suen, Kin Man;
Lin, Chi-Chuan;
George, Roger;
Melo, Fernando A;
Biggs, Eleanor R;
Ahmed, Zamal;
Drake, Melanie N;
Arur, Swathi;
Arold, Stefan T;
Ladbury, John E

Publication type:

Article

Crystal structures of the JAK2 pseudokinase domain and the pathogenic mutant V617F.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 8, p. 754, doi. 10.1038/nsmb.2348

By:

Bandaranayake, Rajintha M;
Ungureanu, Daniela;
Shan, Yibing;
Shaw, David E;
Silvennoinen, Olli;
Hubbard, Stevan R

Publication type:

Article

Structural basis for autoinhibition and phosphorylation-dependent activation of c-Cbl.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 2, p. 184, doi. 10.1038/nsmb.2231

By:

Dou, Hao;
Buetow, Lori;
Hock, Andreas;
Sibbet, Gary J;
Vousden, Karen H;
Huang, Danny T

Publication type:

Article

Mechanistic insights into the activation of oncogenic forms of EGF receptor.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 12, p. 1388, doi. 10.1038/nsmb.2168

By:

Wang, Zhihong;
Longo, Patti A;
Tarrant, Mary Katherine;
Kim, Kwangsoo;
Head, Sarah;
Leahy, Daniel J;
Cole, Philip A

Publication type:

Article

The pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signaling.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 9, p. 971, doi. 10.1038/nsmb.2099

By:

Ungureanu, Daniela;
Jinhua Wu;
Pekkala, Tuija;
Niranjan, Yashavanthi;
Young, Clifford;
Jensen, Ole N.;
Chong-Feng Xu;
Neubert, Thomas A.;
Skoda, Radek C.;
Hubbard, Stevan R.;
Silvennoinen, Olli

Publication type:

Article

Alternative splicing of SYK regulates mitosis and cell survival.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 6, p. 673, doi. 10.1038/nsmb.2040

By:

Prinos, Panagiotis;
Garneau, Daniel;
Lucier, Jean-François;
Gendron, Daniel;
Couture, Sonia;
Boivin, Marianne;
Brosseau, Jean-Philippe;
Lapointe, Elvy;
Thibault, Philippe;
Durand, Mathieu;
Tremblay, Karine;
Gervais-Bird, Julien;
Nwilati, Hanad;
Klinck, Roscoe;
Chabot, Benoit;
Perreault, Jean-Pierre;
Wellinger, Raymund J.;
Elela, Sherif Abou

Publication type:

Article

An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 4, p. 398, doi. 10.1038/nsmb.1782

By:

Seiradake, Elena;
Harlos, Karl;
Sutton, Geoff;
Aricescu, A. Radu;
Jones, E. Yvonne

Publication type:

Article

A potent and highly specific FN3 monobody inhibitor of the Abl SH2 domain.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 4, p. 519, doi. 10.1038/nsmb.1793

By:

Wojcik, John;
Hantschel, Oliver;
Grebien, Florian;
Kaupe, Ines;
Bennett, Keiryn L.;
Barkinge, John;
Jones, Richard B.;
Koide, Akiko;
Superti-Furga, Giulio;
Koide, Shohei

Publication type:

Article

Activation of tyrosine kinases by mutation of the gatekeeper threonine.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 10, p. 1109, doi. 10.1038/nsmb.1486

By:

Azam, Mohammad;
Seelinger, Markus A.;
Gray, Nathanael S.;
Kuriyan, John;
Daley, George Q.

Publication type:

Article

Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 3, p. 251, doi. 10.1038/nsmb.1388

By:

Jinhua Wu;
Tseng, Yolanda D.;
Chong-Feng Xu;
Neubert, Thomas A.;
White, Morris F.;
Hubbard, Stevan R.

Publication type:

Article

Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 6, p. 503, doi. 10.1038/nsmb1241

By:

Kobashigawa, Yoshihiro;
Sakai, Mieko;
Naito, Masato;
Yokochi, Masashi;
Kumeta, Hiroyuki;
Makino, Yoshinori;
Ogura, Kenji;
Tanaka, Shinya;
Inagaki, Fuyuhiko

Publication type:

Article

Crystal structures of the Tie2 receptor ectodomain and the angiopoietin-2–Tie2 complex.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 6, p. 524, doi. 10.1038/nsmb1101

By:

Barton, William A;
Tzvetkova-Robev, Dorothea;
Miranda, Edward P;
Kolev, Momchil V;
Rajashankar, Kanagalaghatta R;
Himanen, Juha P;
Nikolov, Dimitar B

Publication type:

Article