Works matching DE "PYRUVATE dehydrogenase kinase"
Results: 379
Identifying selective PDHK inhibitors using coupled tensor matrix completion and experimental validation.
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- Discover Artificial Intelligence, 2024, v. 4, n. 1, p. 1, doi. 10.1007/s44163-024-00202-8
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- Article
Improved Ethanol Tolerance and Production in Pyruvate Dehydrogenase Mutant of Saccharomyces cerevisiae.
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- International Journal of High School Research, 2023, v. 5, n. 5, p. 138, doi. 10.36838/v5i5.25
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- Article
Identification of Bacterial Proteins in the Gut of Sunn pest, Eurygaster integriceps.
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- Journal of Cell & Molecular Research, 2020, v. 12, n. 2, p. 97, doi. 10.22067/jcmr.2021.64305.0
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- Article
Therapeutic potential of microglial SMEK1 in regulating H3K9 lactylation in cerebral ischemia-reperfusion.
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- Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07425-6
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- Article
IP<sub>3</sub>R at ER-Mitochondrial Contact Sites: Beyond the IP<sub>3</sub>R-GRP75-VDAC1 Ca<sup>2+</sup> Funnel.
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- Contact (25152564), 2023, v. 6, p. 1, doi. 10.1177/25152564231181020
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- Article
Metabolic checkpoint of ferroptosis resistance.
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- Molecular & Cellular Oncology, 2021, v. 8, n. 3, p. 1, doi. 10.1080/23723556.2021.1901558
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- Article
Inhibitory effect of surface prereacted glass-ionomer (S-PRG) eluate against adhesion and colonization by Streptococcus mutans.
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- Scientific Reports, 2018, p. 1, doi. 10.1038/s41598-018-23354-x
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- Article
Elevated Level of Cerebrospinal Fluid Pyruvate Dehydrogenase Kinase 4 Is a Predictive Biomarker of Clinical Outcome after Subarachnoid Hemorrhage.
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- Brain Sciences (2076-3425), 2022, v. 12, n. 11, p. 1507, doi. 10.3390/brainsci12111507
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- Article
Bioenergy Crisis in Coronavirus Diseases?
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- 2020
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- Editorial
Angiotensin II Alters Mitochondrial Membrane Potential and Lipid Metabolism in Rat Colonic Epithelial Cells.
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- Biomolecules (2218-273X), 2024, v. 14, n. 8, p. 974, doi. 10.3390/biom14080974
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- Article
Interaction between Butyrate and Tumor Necrosis Factor α in Primary Rat Colonocytes.
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- Biomolecules (2218-273X), 2023, v. 13, n. 2, p. 258, doi. 10.3390/biom13020258
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- Article
Arginine methylation of PPP1CA by CARM1 regulates glucose metabolism and affects osteogenic differentiation and osteoclastic differentiation.
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- Clinical & Translational Medicine, 2023, v. 13, n. 9, p. 1, doi. 10.1002/ctm2.1369
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- Article
Cyclosporinemodulates neutrophil functions via the SIRT6--HIF-1α--glycolysis axis to alleviate severe ulcerative colitis.
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- Clinical & Translational Medicine, 2021, v. 11, n. 2, p. 1, doi. 10.1002/ctm2.334
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- Publication type:
- Article
Thermodynamics in cancers: opposing interactions between PPAR gamma and the canonical WNT/beta‐catenin pathway.
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- Clinical & Translational Medicine, 2017, v. 6, n. 1, p. 1, doi. 10.1186/s40169-017-0144-7
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- Publication type:
- Article
Melatonin: a modulator in metabolic rewiring in T-cell malignancies.
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- Frontiers in Oncology, 2024, p. 1, doi. 10.3389/fonc.2023.1248339
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- Publication type:
- Article
Glycolysis, monocarboxylate transport, and purinergic signaling are key events in Eimeria bovis-induced NETosis.
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- Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.842482
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- Article
Effects of Type 2 Diabetes Mellitus on Gene Expressions of Mouse Meibomian Glands.
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- Current Eye Research, 2020, v. 45, n. 1, p. 72, doi. 10.1080/02713683.2019.1656750
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- Article
Inhibition of the ketolytic acetyl CoA supply to tumors could be their "Achilles heel".
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- International Journal of Cancer, 2020, v. 147, n. 6, p. 1755, doi. 10.1002/ijc.32979
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- Article
The mechanism of cancer cell death by PARP inhibitors goes beyond DNA damage alone.
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- International Journal of Cancer, 2019, v. 145, n. 9, p. 2594, doi. 10.1002/ijc.32392
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- Publication type:
- Article
Reply to: Potential contribution of PEP carboxykinase-dependent malate dismutation to the hypoxia response in C. elegans.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39511-4
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- Publication type:
- Article
Modulation of Muscle Fiber Compositions in Response to Hypoxia via Pyruvate Dehydrogenase Kinase-1.
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- Frontiers in Physiology, 2016, v. 7, p. 1, doi. 10.3389/fphys.2016.00604
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- Article
Altered Left Ventricular Rat Gene Expression Induced by the Myosin Activator Omecamtiv Mecarbil.
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- Genes, 2023, v. 14, n. 1, p. 122, doi. 10.3390/genes14010122
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- Article
Comparison between the Transcriptomes of 'KDML105' Rice and a Salt-Tolerant Chromosome Segment Substitution Line.
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- Genes, 2019, v. 10, n. 10, p. 742, doi. 10.3390/genes10100742
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- Article
A Comparative QSAR Analysis, Molecular Docking and PLIF Studies of Some N-arylphenyl-2,2-Dichloroacetamide Analogues as Anticancer Agents.
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- Iranian Journal of Pharmaceutical Research, 2017, v. 16, n. 3, p. 981
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- Article
Dual-targeting of aberrant glucose metabolism in glioblastoma.
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- Journal of Experimental & Clinical Cancer Research (17569966), 2015, v. 34, n. 1, p. 1, doi. 10.1186/S13046-015-0130-0
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- Article
A novel genetic model provides a unique perspective on the relationship between postexercise glycogen concentration and increases in the abundance of key metabolic proteins after acute exercise.
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- PLoS ONE, 2024, v. 19, n. 1, p. 1, doi. 10.1371/journal.pone.0295964
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- Publication type:
- Article
LncRNA MEG3 promotes endoplasmic reticulum stress and suppresses proliferation and invasion of colorectal carcinoma cells through the MEG3/miR-103a-3p/PDHB ceRNA pathway.
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- Neoplasma, 2021, v. 68, n. 2, p. 362, doi. 10.4149/neo_2020_200813N858
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- Article
Pyruvate dehydrogenase kinase 1 and carbonic anhydrase IX targeting in hypoxic tumors.
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- Neoplasma, 2019, v. 66, n. 1, p. 63, doi. 10.4149/neo_2018_180531N357
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- Article
Chronic kidney disease reduces muscle mitochondria and exercise endurance and its exacerbation by dietary protein through inactivation of pyruvate dehydrogenase.
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- Kidney International, 2014, v. 85, n. 6, p. 1330, doi. 10.1038/ki.2013.473
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- Publication type:
- Article
Metabolic regulation of intrasynovial flexor tendon repair: The effects of dichloroacetate administration on early tendon healing in a canine model.
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- Journal of Orthopaedic Research, 2023, v. 41, n. 2, p. 278, doi. 10.1002/jor.25354
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- Article
MuRF1 deficiency prevents age‐related fat weight gain, possibly through accumulation of PDK4 in skeletal muscle mitochondria in older mice.
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- Journal of Orthopaedic Research, 2022, v. 40, n. 5, p. 1026, doi. 10.1002/jor.25131
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- Article
Altered Glycolysis, Mitochondrial Biogenesis, Autophagy and Apoptosis in Peritoneal Endometriosis in Adolescents.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 8, p. 4238, doi. 10.3390/ijms25084238
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- Article
Natural Product-Based Glycolysis Inhibitors as a Therapeutic Strategy for Epidermal Growth Factor Receptor–Tyrosine Kinase Inhibitor-Resistant Non-Small Cell Lung Cancer.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 2, p. 807, doi. 10.3390/ijms25020807
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- Article
Association of Phosphorylated Pyruvate Dehydrogenase with Pyruvate Kinase M2 Promotes PKM2 Stability in Response to Insulin.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 18, p. 13697, doi. 10.3390/ijms241813697
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- Article
Intra-Articular Lactate Dehydrogenase A Inhibitor Oxamate Reduces Experimental Osteoarthritis and Nociception in Rats via Possible Alteration of Glycolysis-Related Protein Expression in Cartilage Tissue.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 13, p. 10770, doi. 10.3390/ijms241310770
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- Article
Human Umbilical Cord Mesenchymal Stem Cells Protect against Renal Ischemia-Reperfusion Injury by Secreting Extracellular Vesicles Loaded with miR-148b-3p That Target Pyruvate Dehydrogenase Kinase 4 to Inhibit Endoplasmic Reticulum Stress at the Reperfusion Stages
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- International Journal of Molecular Sciences, 2023, v. 24, n. 10, p. 8899, doi. 10.3390/ijms24108899
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- Article
Thermal Titration Molecular Dynamics (TTMD): Not Your Usual Post-Docking Refinement.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 4, p. 3596, doi. 10.3390/ijms24043596
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- Publication type:
- Article
Anti-Metastatic Effect of Pyruvate Dehydrogenase Kinase 4 Inhibition in Bladder Cancer via the ERK, SRC, and JNK Pathways.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 21, p. 13240, doi. 10.3390/ijms232113240
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- Publication type:
- Article
Curcumin Sensitises Cancerous Kidney Cells to TRAIL Induced Apoptosis via Let-7C Mediated Deregulation of Cell Cycle Proteins and Cellular Metabolism.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 17, p. 9569, doi. 10.3390/ijms23179569
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- Article
Pyruvate Dehydrogenase Kinase Inhibition by Dichloroacetate in Melanoma Cells Unveils Metabolic Vulnerabilities.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 7, p. 3745, doi. 10.3390/ijms23073745
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- Article
Cassiaside C Inhibits M1 Polarization of Macrophages by Downregulating Glycolysis.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 3, p. 1696, doi. 10.3390/ijms23031696
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- Publication type:
- Article
Cardioprotective Effects of Palmitoleic Acid (C16:1n7) in a Mouse Model of Catecholamine-Induced Cardiac Damage Are Mediated by PPAR Activation.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 23, p. 12695, doi. 10.3390/ijms222312695
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- Article
Impact of Sodium Dichloroacetate Alone and in Combination Therapies on Lung Tumor Growth and Metastasis.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 22, p. 12553, doi. 10.3390/ijms222212553
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- Article
Metformin and Dichloroacetate Suppress Proliferation of Liver Cancer Cells by Inhibiting mTOR Complex 1.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 18, p. 10027, doi. 10.3390/ijms221810027
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- Article
Suppression of Pyruvate Dehydrogenase Kinase by Dichloroacetate in Cancer and Skeletal Muscle Cells Is Isoform Specific and Partially Independent of HIF-1α.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 16, p. 8610, doi. 10.3390/ijms22168610
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- Article
Five Days Periodic Fasting Elevates Levels of Longevity Related Christensenella and Sirtuin Expression in Humans.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2331, doi. 10.3390/ijms22052331
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- Article
Anti-Warburg Effect of Melatonin: A Proposed Mechanism to Explain its Inhibition of Multiple Diseases.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 2, p. 764, doi. 10.3390/ijms22020764
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- Article
Dichloroacetate Radiosensitizes Hypoxic Breast Cancer Cells.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 24, p. 9367, doi. 10.3390/ijms21249367
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- Article
Ilimaquinone Induces the Apoptotic Cell Death of Cancer Cells by Reducing Pyruvate Dehydrogenase Kinase 1 Activity.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 17, p. 6021, doi. 10.3390/ijms21176021
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- Article
PPARδ and FOXO1 Mediate Palmitate-Induced Inhibition of Muscle Pyruvate Dehydrogenase Complex and CHO Oxidation, Events Reversed by Electrical Pulse Stimulation.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 16, p. 5942, doi. 10.3390/ijms21165942
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- Publication type:
- Article