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- Title
Associations between the Global Diet Quality Score and risk of type 2 diabetes: Tehran lipid and glucose study.
- Authors
Daei, Shahrzad; Hosseini-Esfahani, Firoozeh; Ildarabadi, Azam; Mirmiran, Parvin; Azizi, Fereidoun
- Abstract
Background: Previous studies reported that focusing on healthy lifestyle, especially high diet quality is necessary for preventing type 2 diabetes (T2D). This study investigated the association between the innovative index, the Global Diet Quality Score (GDQS), and the risk of Type 2 Diabetes incidence. Methods: In this secondary analysis, we included elective adult participants (n = 5948) from the third and fourth survey of the Tehran Lipid and Glucose Study. Participants checked out until the sixth phase with an average follow-up of 6.65 years. Expert nutritionists collected dietary data using a valid and reliable semi-quantitative food frequency questionnaire. The GDQS were calculated, including healthy and unhealthy food group scores. Biochemical and anthropometric characteristics were assessed during the first and follow-up surveys. Multivariable Cox proportional hazards regression models were used to estimate the progression of T2D in association with the GDQS. Results: This study was implemented on 2,688 men and 3,260 women, respectively with the mean (SD) age of 41.5(14.1) and 39.3(13.02) years. A total of 524 subjects were found to have had T2D incidence. The healthy component of GDQS was conversely associated with T2D incidence [HR: 1, 0.91 (0.84–0.98), 0.91 (0.84–0.98), 0.84 (0.77–0.92) P trend = <0.001] in an adjusted model. The unhealthy component of GDQS was conversely associated with T2D incidence in an adjusted model [HR: 1, 0.86 (0.80–0.92), 0.93 (0.86–1.01), 0.89 (0.81–0.98) P trend = 0.009]. Conclusion: The results of this study suggested that higher adherence to the healthy component of GDQS and lower intake of the unhealthy component decreased the risk of T2D incidence.
- Subjects
TYPE 2 diabetes; DISEASE risk factors; SECONDARY analysis; PROPORTIONAL hazards models; GLUCOSE
- Publication
PLoS ONE, 2025, Vol 20, Issue 1, p1
- ISSN
1932-6203
- Publication type
Academic Journal
- DOI
10.1371/journal.pone.0313886