Works matching DE "INSULIN synthesis"

Results: 234

Effects of silibinin on apoptosis and insulin secretion in rat RINm5F pancreatic β-cells.

Published in:

Biotechnic & Histochemistry, 2023, v. 98, n. 3, p. 201, doi. 10.1080/10520295.2022.2154840

By:

Mazraesefidi, Maryam;
Mahmoodi, Mehdi;
Hajizadeh, Mohammadreza

Publication type:

Article

Synthesis of functionally active human proinsulin in a cell-free translation system.

Published in:

Doklady Biochemistry & Biophysics, 2005, v. 401, n. 1-6, p. 154, doi. 10.1007/s10628-005-0058-y

By:

Kommer, A. A.;
Dashkova, I. G.;
Esipov, R. S.;
Miroshnikov, A. I.;
Spirin, A. S.

Publication type:

Article

Construction of Insulin 18-mer Nanoassemblies Driven by Coordination to Iron(II) and Zinc(II) Ions at Distinct Sites.

Published in:

Angewandte Chemie, 2016, v. 128, n. 7, p. 2424, doi. 10.1002/ange.201509088

By:

Munch, Henrik K.;
Nygaard, Jesper;
Christensen, Niels Johan;
Engelbrekt, Christian;
Østergaard, Mads;
Porsgaard, Trine;
Hoeg‐Jensen, Thomas;
Zhang, Jingdong;
Arleth, Lise;
Thulstrup, Peter W.;
Jensen, Knud J.

Publication type:

Article

A Synthetic Route to Human Insulin Using Isoacyl Peptides.

Published in:

Angewandte Chemie, 2014, v. 126, n. 15, p. 4064, doi. 10.1002/ange.201310735

By:

Liu, Fa;
Luo, Ethan Y.;
Flora, David B.;
Mezo, Adam R.

Publication type:

Article

(+)-Catechin mitigates impairment in insulin secretion and beta cell damage in methylglyoxal-induced pancreatic beta cells.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09338-3

By:

Anaga, Nair;
Lekshmy, Krishnan;
Purushothaman, Jayamurthy

Publication type:

Article

The zinc transporter ZNT3 co-localizes with insulin in INS-1E pancreatic beta cells and influences cell survival, insulin secretion capacity, and ZNT8 expression.

Published in:

BioMetals, 2016, v. 29, n. 2, p. 287, doi. 10.1007/s10534-016-9915-7

By:

Smidt, Kamille;
Larsen, Agnete;
Brønden, Andreas;
Sørensen, Karen;
Nielsen, Julie;
Praetorius, Jeppe;
Martensen, Pia;
Rungby, Jørgen

Publication type:

Article

Medium and copy number effects on the secretion of human proinsulin in Escherichia coli using the universal stress promoters uspA and uspB.

Published in:

Applied Microbiology & Biotechnology, 2003, v. 61, n. 5/6, p. 495, doi. 10.1007/s00253-003-1232-8

By:

Mergulhão, F. J. M.;
Monteiro, G. A.;
Larsson, G.;
Sandén, A. M.;
Farewell, A.;
Nystrom, T.;
Cabral, J. M. S.;
Taipa, M. A.

Publication type:

Article

Dityrosine administration induces dysfunction of insulin secretion accompanied by diminished thyroid hormones T3 function in pancreas of mice.

Published in:

Amino Acids, 2017, v. 49, n. 8, p. 1401, doi. 10.1007/s00726-017-2442-1

By:

Ding, Yin-Yi;
Li, Zhu-Qing;
Cheng, Xiang-Rong;
Ran, Yu-Mei;
Wu, Sha-Ji;
Shi, Yonghui;
Le, Guowei

Publication type:

Article

Impaired Glucose Metabolism in Young Offspring of Female Rats with Hypothyroidism.

Published in:

Journal of Diabetes Research, 2019, p. 1, doi. 10.1155/2019/4713906

By:

Liu, Zhoujun;
Chen, Yu;
Chen, Guofang;
Mao, Xiaodong;
Wei, Xiao;
Li, Xingjia;
Xu, Yijiao;
Jiang, Fan;
Wang, Kun;
Liu, Chao

Publication type:

Article

Measurement of Pulsatile Insulin Secretion: Rationale and Methodology.

Published in:

Metabolites (2218-1989), 2021, v. 11, n. 7, p. 409, doi. 10.3390/metabo11070409

By:

Laurenti, Marcello C.;
Matveyenko, Aleksey;
Vella, Adrian

Publication type:

Article

What Is the Metabolic Amplification of Insulin Secretion and Is it (Still) Relevant?

Published in:

Metabolites (2218-1989), 2021, v. 11, n. 6, p. 355, doi. 10.3390/metabo11060355

By:

Rustenbeck, Ingo;
Schulze, Torben;
Morsi, Mai;
Alshafei, Mohammed;
Panten, Uwe

Publication type:

Article

Efficacy and Tolerability of Pioglitazone in Patients with Type 2 Diabetes Mellitus: Comparison with Other Oral Antihyperglycaemic Agents.

Published in:: Drugs, 2010, v. 70, n. 15, p. 1945, doi. 10.2165/11538100-000000000-00000
Publication type:: Article

An Autonomous Cannabinoid System in Islets of Langerhans.

Published in:

Frontiers in Endocrinology, 2021, v. 12, p. 1, doi. 10.3389/fendo.2021.699661

By:

Aseer, Kanikkai Raja;
Egan, Josephine M.

Publication type:

Article

Upregulation of α-ENaC induces pancreatic β-cell dysfunction, ER stress, and SIRT2 degradation.

Published in:

Journal of Biomedical Research, 2024, v. 38, n. 3, p. 241, doi. 10.7555/JBR.37.20230128

By:

Xue Zhang;
Dan Zhang;
Lei Huo;
Xin Zhou;
Jia Zhang;
Min Li;
Dongming Su;
Peng Sun;
Fang Chen;
Xiubin Liang

Publication type:

Article

A different kind of synthesis: artificial synthesis of insulin in socialist China.

Published in:

History & Technology, 2019, v. 35, n. 4, p. 453, doi. 10.1080/07341512.2019.1694124

By:

Ling, Vivian;
Jiang, Lijing

Publication type:

Article

Interaction of HuDA and PABP at 5'UTR of mouse insulin2 regulates insulin biosynthesis.

Published in:

PLoS ONE, 2018, v. 13, n. 3, p. 1, doi. 10.1371/journal.pone.0194482

By:

Pandey, Poonam R.;
Sarwade, Rucha D.;
Khalique, Abdul;
Seshadri, Vasudevan

Publication type:

Article

Insulin Stimulation of Protein Synthesis and mTOR Signaling in Chick Myotube Cultures.

Published in:

Journal of Poultry Science, 2020, v. 57, n. 3, p. 205, doi. 10.2141/jpsa.0190082

By:

Kazuki Nakashima;
Aiko Ishida;
Saki Shimamoto;
Daichi Ijiri;
Akira Ohtsuka

Publication type:

Article

Gut insulin from Foxo1 loss.

Published in:

Nature Genetics, 2012, v. 44, n. 4, p. 363, doi. 10.1038/ng.2226

By:

Kim, Seung K

Publication type:

Article

Meal Test for Glucose-Dependent Insulinotropic Peptide (GIP) in Obese and Type 2 Diabetic Patients.

Published in:: Physiological Research, 2010, v. 59, n. 5, p. 749, doi. 10.33549/physiolres.931893
Publication type:: Article

Front Cover: Substitution of an Internal Disulfide Bridge with a Diselenide Enhances both Foldability and Stability of Human Insulin (Chem. Eur. J. 36/2019).

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 36, p. 8426, doi. 10.1002/chem.201901973

By:

Weil‐Ktorza, Orit;
Rege, Nischay;
Lansky, Shifra;
Shalev, Deborah E.;
Shoham, Gil;
Weiss, Michael A.;
Metanis, Norman

Publication type:

Article

Substitution of an Internal Disulfide Bridge with a Diselenide Enhances both Foldability and Stability of Human Insulin.

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 36, p. 8513, doi. 10.1002/chem.201900892

By:

Weil‐Ktorza, Orit;
Rege, Nischay;
Lansky, Shifra;
Shalev, Deborah E.;
Shoham, Gil;
Weiss, Michael A.;
Metanis, Norman

Publication type:

Article

Scope and Limitations of Fmoc Chemistry SPPS-Based Approaches to the Total Synthesis of Insulin Lispro via Ester Insulin.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 7, p. 1709, doi. 10.1002/chem.201605578

By:

Dhayalan, Balamurugan;
Mandal, Kalyaneswar;
Rege, Nischay;
Weiss, Michael A.;
Eitel, Simon H.;
Meier, Thomas;
Schoenleber, Ralph O.;
Kent, Stephen B. H.

Publication type:

Article

The role of the farnesoid X receptor in diabetes and its complications.

Published in:

Molecular & Cellular Biochemistry, 2025, v. 480, n. 5, p. 2725, doi. 10.1007/s11010-024-05162-2

By:

Zhang, Shengnan;
Zhang, Dandan;
Xu, Kui;
Huang, Xingqiong;
Chen, Qingjie;
Chen, Mi

Publication type:

Article

Role of Wnt signaling pathways in type 2 diabetes mellitus.

Published in:

Molecular & Cellular Biochemistry, 2021, v. 476, n. 5, p. 2219, doi. 10.1007/s11010-021-04086-5

By:

Chen, Jing;
Ning, Chong;
Mu, Jingjing;
Li, Dongnan;
Ma, Yan;
Meng, Xianjun

Publication type:

Article

Attenuating effect of silibinin on palmitic acid-induced apoptosis and mitochondrial dysfunction in pancreatic β-cells is mediated by estrogen receptor alpha.

Published in:

Molecular & Cellular Biochemistry, 2019, v. 460, n. 1/2, p. 81, doi. 10.1007/s11010-019-03572-1

By:

Sun, Yue;
Yang, Jing;
Liu, Weiwei;
Yao, Guodong;
Xu, Fanxing;
Hayashi, Toshihiko;
Onodera, Satoshi;
Ikejima, Takashi

Publication type:

Article

Molecular and functional characterization of glycogen synthase in the porcine satellite cells under insulin treatment.

Published in:

Molecular & Cellular Biochemistry, 2012, v. 360, n. 1/2, p. 169, doi. 10.1007/s11010-011-1054-4

By:

Wang, Linjie;
Xiong, Yuanzhu;
Zuo, Bo;
Lei, Minggang;
Ren, Zhuqing;
Xu, Dequan

Publication type:

Article

Sitagliptin-induced pancreatitis - a longer road than expected.

Published in:

Clinical Case Reports, 2014, v. 2, n. 4, p. 149, doi. 10.1002/ccr3.83

By:

Nelson, Matthew;
Bhandari, Niyati;
Wener, Jill

Publication type:

Article

Metformin restores prohormone processing enzymes and normalizes aberrations in secretion of proinsulin and insulin in palmitate‐exposed human islets.

Published in:

Diabetes, Obesity & Metabolism, 2023, v. 25, n. 12, p. 3757, doi. 10.1111/dom.15270

By:

Wen, Quan;
Chowdhury, Azazul Islam;
Aydin, Banu;
Shekha, Mudhir;
Stenlid, Rasmus;
Forslund, Anders;
Bergsten, Peter

Publication type:

Article

The kinase PKD3 provides negative feedback on cholesterol and triglyceride synthesis by suppressing insulin signaling.

Published in:

Science Signaling, 2019, v. 12, n. 593, p. 1, doi. 10.1126/scisignal.aav9150

By:

Mayer, Alexander E.;
Löffler, Mona C.;
Loza Valdés, Angel E.;
Schmitz, Werner;
El-Merahbi, Rabih;
Viera, Jonathan Trujillo;
Erk, Manuela;
Zhang, Thianzhou;
Braun, Ursula;
Heikenwalder, Mathias;
Leitges, Michael;
Schulze, Almut;
Sumara, Grzegorz

Publication type:

Article

miR-196b-Mediated Translation Regulation of Mouse <i>Insulin2</i> via the 5′UTR.

Published in:

PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0101084

By:

Panda, Amaresh C.;
Sahu, Itishri;
Kulkarni, Shardul D.;
Martindale, Jennifer L.;
Abdelmohsen, Kotb;
Vindu, Arya;
Joseph, Jomon;
Gorospe, Myriam;
Seshadri, Vasudevan

Publication type:

Article

<i>Perk</i> Gene Dosage Regulates Glucose Homeostasis by Modulating Pancreatic β-Cell Functions.

Published in:

PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0099684

By:

Wang, Rong;
Munoz, Elyse E.;
Zhu, Siying;
McGrath, Barbara C.;
Cavener, Douglas R.

Publication type:

Article

Folate Deficiency Triggers an Oxidative-Nitrosative Stress-Mediated Apoptotic Cell Death and Impedes Insulin Biosynthesis in RINm5F Pancreatic Islet β–Cells: Relevant to the Pathogenesis of Diabetes.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0077931

By:

Hsu, Hung-Chih;
Chiou, Jeng-Fong;
Wang, Yu-Huei;
Chen, Chia-Hui;
Mau, Shin-Yi;
Ho, Chun-Te;
Chang, Pey-Jium;
Liu, Tsan-Zon;
Chen, Ching-Hsein

Publication type:

Article

Adequately Adapted Insulin Secretion and Decreased Hepatic Insulin Extraction Cause Elevated Insulin Concentrations in Insulin Resistant Non-Diabetic Adrenal Incidentaloma Patients.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077326

By:

Anderwald, Christian-Heinz;
Tura, Andrea;
Gessl, Alois;
Luger, Anton;
Pacini, Giovanni;
Krebs, Michael

Publication type:

Article

Function-Based Discovery of Significant Transcriptional Temporal Patterns in Insulin Stimulated Muscle Cells.

Published in:

PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0032391

By:

Camillo, Barbara Di;
Irving, Brian A.;
Schimke, Jill;
Sanavia, Tiziana;
Toffolo, Gianna;
Cobelli, Claudio;
Sreekumaran Nair, K.

Publication type:

Article

Free Fatty Acid-Induced PP2A Hyperactivity Selectively Impairs Hepatic Insulin Action on Glucose Metabolism.

Published in:

PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0027424

By:

Galbo, Thomas;
Olsen, Grith Skytte;
Quistorff, Bjørn;
Nishimura, Erica

Publication type:

Article

AGEs Decrease Insulin Synthesis in Pancreatic β-Cell by Repressing Pdx-1 Protein Expression at the Post-Translational Level.

Published in:

PLoS ONE, 2011, v. 6, n. 4, p. 1, doi. 10.1371/journal.pone.0018782

By:

Tingting Shu;
Yunxia Zhu;
Hongdong Wang;
Yan Lin;
Zhuo Ma;
Xiao Han

Publication type:

Article

Insulin Resistance Is Not Conserved in Myotubes Established from Women with PCOS.

Published in:

PLoS ONE, 2010, v. 5, n. 12, p. 1, doi. 10.1371/journal.pone.0014469

By:

Eriksen, Mette;
Pørneki, Ann Dorte;
Skov, Vibe;
Burns, Jorge S.;
Beck-Nielsen, Henning;
Glintborg, Dorte;
Gaster, Michael

Publication type:

Article

Bitter Taste Receptors Influence Glucose Homeostasis.

Published in:

PLoS ONE, 2008, v. 3, n. 12, p. 1, doi. 10.1371/journal.pone.0003974

By:

Dotson, Cedrick D.;
Lan Zhang;
Hong Xu;
Yu-Kyong Shin;
Vigues, Stephan;
Ott, Sandra H.;
Elson, Amanda E. T.;
Hyun Jin Choi;
Shaw, Hillary;
Egan, Josephine M.;
Mitchell, Braxton D.;
Xiaodong Li;
Steinle, Nanette I.;
Munger, Steven D.

Publication type:

Article

Pancreatic Insulin Content Regulation by the Estrogen Receptor ERα.

Published in:

PLoS ONE, 2008, v. 3, n. 4, p. 1, doi. 10.1371/journal.pone.0002069

By:

Alonso-Magdalena, Paloma;
Ropero, Ana B.;
Carrera, M. Pilar;
Cederroth, Christopher R.;
Baquié, Mathurin;
Gauthier, Benoit R.;
Nef, Serge;
Stefani, Enrico;
Nadal, Angel

Publication type:

Article

Abnormal expression of miR-454-3p in type 2 diabetes mellitus induces dysfunction of pancreatic β cells by regulating Yy1.

Published in:

Diabetes & Vascular Disease Research, 2025, v. 22, n. 2, p. 1, doi. 10.1177/14791641251335923

By:

Liu, Mei-xiao;
Zhang, Hai-feng;
Liu, Ting;
Liu, Jian-hui;
Zhang, Lin-qi;
Zhu, Jian-zhong

Publication type:

Article

Evaluation of Antidiabetic and Antihyperlipidemic Effects of Methanolic Extract of Verbascum thapsus in Alloxan-Induced Diabetic Albino Mice.

Published in:

Pakistan Journal of Weed Science Research, 2023, v. 29, n. 2, p. 1, doi. 10.17582/journal.PJWSR/2023/29.1.1.8

By:

Khan, Waheed;
Khan, Muhammad Ajmal;
Khan, Bakhtawar;
Amin, Aftab;
Ali, Muhsin;
Farid, Awais;
Hazrat, Ali;
Yahya, Muhammad

Publication type:

Article

Evaluation of Antidiabetic and Antihyperlipidemic Effects of Methanolic Extract of Verbascum thapsus in Alloxan-Induced Diabetic Albino Mice.

Published in:

Pakistan Journal of Weed Science Research, 2023, v. 29, n. 1, p. 1, doi. 10.17582/journal.PJWSR/2023/29.1.1.8

By:

Khan, Waheed;
Khan, Muhammad Ajmal;
Khan, Bakhtawar;
Amin, Aftab;
Ali, Muhsin;
Farid, Awais;
Hazrat, Ali;
Yahya, Muhammad

Publication type:

Article

Troglitazone treatment increases protein kinase B phosphorylation in skeletal muscle of normoglycemic subjects at risk for the development of type 2 diabetes.

Published in:

2002

By:

Meyer, Marco M.;
Levin, Klaus;
Grimmsmann, Thomas;
Perwitz, Nina;
Eirich, Alexandra;
Beck-Nielsen, Henning;
Klein, Harald H.;
Klein, H.H.

Publication type:

journal article

Insulin production by human embryonic stem cells.

Published in:

2001

By:

Assady, Suheir;
Maor, Gila;
Amit, Michal;
Itskovitz-Eldor, Joseph;
Skorecki, Karl L.;
Tzukerman, Maty;
Assady, S;
Maor, G;
Amit, M;
Itskovitz-Eldor, J;
Skorecki, K L;
Tzukerman, M

Publication type:

journal article

Evidence that insulin is imprinted in the human yolk sac.

Published in:

2001

By:

Moore, Gudrun E.;
Abu-Amero, Sayeda N.;
Bell, Gill;
Wakeling, Emma L.;
Kingsnorth, Amanda;
Stanier, Philip;
Jauniaux, Eric;
Bennett, Simon T.;
Moore, G E;
Abu-Amero, S N;
Bell, G;
Wakeling, E L;
Kingsnorth, A;
Stanier, P;
Jauniaux, E;
Bennett, S T

Publication type:

journal article

Insulin enhances the bradykinin response in L8 rat skeletal myoblasts.

Published in:

2000

By:

Kudoh, Akira;
Dietze, Guenther J.;
Rabito, Sara F.;
Kudoh, A;
Dietze, G J;
Rabito, S F

Publication type:

journal article

High-fat meals reduce 24-h circulating leptin concentrations in women.

Published in:

Diabetes, 1999, v. 48, n. 2, p. 334, doi. 10.2337/diabetes.48.2.334

By:

Havel, Peter J.;
Townsend, Raymond;
Chaump, Leslie;
Teff, Karen

Publication type:

Article

THE CORRELATION BETWEEN AMYLIN AND INSULIN BY TREATMENT WITH 2-DEOXY-D-GLUCOSE AND/OR MANNOSE IN RAT INSULINOMA INS-1E CELLS.

Published in:

Journal of Physiology & Pharmacology, 2021, v. 72, n. 4, p. 1, doi. 10.26402/jpp.2021.4.03

By:

Kim, H. S.;
JOO, S. S.;
YOO, Y.-M.

Publication type:

Article

MicroRNA‐29‐mediated cross‐talk between metabolic organs in the pathogenesis of diabetes mellitus and its complications: A narrative review.

Published in:

Cell Biochemistry & Function, 2024, v. 42, n. 4, p. 1, doi. 10.1002/cbf.4053

By:

Yesuf, Hassen Ahmed;
Molla, Meseret Derbew;
Malik, Tabarak;
Seyoum Wendimagegn, Zeru;
Yimer, Yadelew

Publication type:

Article

The mechanisms of lncRNA Tug1 in islet dysfunction in a mouse model of intrauterine growth retardation.

Published in:

Cell Biochemistry & Function, 2020, v. 38, n. 8, p. 1129, doi. 10.1002/cbf.3575

By:

Li, Yihui;
Dai, Chengting;
Yuan, Yi;
You, Lianghui;
Yuan, Qingxin

Publication type:

Article