Works matching DE "PROSTAGLANDIN antagonists"

Results: 64

Synthesis and Intracellular Redox Cycling of Natural Quinones and Their Analogues and Identification of Indoleamine-2,3-dioxygenase (IDO) as Potential Target for Anticancer Activity.

Published in:

Angewandte Chemie, 2015, v. 127, n. 30, p. 8864, doi. 10.1002/ange.201503323

By:

Blunt, Christopher E.;
Torcuk, Canan;
Liu, Yang;
Lewis, William;
Siegel, David;
Ross, David;
Moody, Christopher J.

Publication type:

Article

Targeting the PGD/CRTH2/DP1 Signaling Pathway in Asthma and Allergic Disease: Current Status and Future Perspectives.

Published in:

Drugs, 2017, v. 77, n. 12, p. 1281, doi. 10.1007/s40265-017-0777-2

By:

Kupczyk, Maciej;
Kuna, Piotr

Publication type:

Article

Cortical hyperostosis as a side-effect of prolonged use of prostaglandins.

Published in:

2016

By:

Rivero Jiménez, Natalia;
Bret-Zurita, Montserrat;
García-Guereta Silva, Luis;
Rivero Jiménez, Natalia;
García-Guereta Silva, Luis

Publication type:

journal article

Exploring the insulin secretory properties of the PGD2-GPR44/DP2 axis in vitro and in a randomized phase-1 trial of type 2 diabetes patients.

Published in:

PLoS ONE, 2018, v. 13, n. 12, p. 1, doi. 10.1371/journal.pone.0208998

By:

Skrtic, Stanko;
Tyrberg, Björn;
Broberg, Malin;
Ericsson, Hans;
Schnecke, Volker;
Kjaer, Magnus;
Hompesch, Marcus;
Andersson, Eva-Marie;
Ryberg, Erik;
Aivazidis, Alexander;
Wennberg Huldt, Charlotte;
Löfgren, Lars;
Morrow, Linda;
Parkinson, Joanna;
Rydén-Bergsten, Tina;
Watkins, Elaine;
Sörhede Winzell, Maria

Publication type:

Article

Prostaglandin E2 and programmed cell death 1 signaling coordinately impair CTL function and survival during chronic viral infection.

Published in:

Nature Medicine, 2015, v. 21, n. 4, p. 327, doi. 10.1038/nm.3831

By:

Chen, Jonathan H;
Perry, Curtis J;
Tsui, Yao-Chen;
Staron, Matthew M;
Parish, Ian A;
Dominguez, Claudia X;
Rosenberg, Daniel W;
Kaech, Susan M

Publication type:

Article

Repeated application of glucocorticoids exacerbate pruritus via inhibition of prostaglandin D2 production of mast cells in a murine model of allergic contact dermatitis.

Published in:

Journal of Toxicological Sciences, 2012, v. 37, n. 6, p. 1127, doi. 10.2131/jts.37.1127

By:

Katsunori Yamaura;
Ryosuke Doi;
Eriko Suwa;
Koichi Ueno

Publication type:

Article

Exposure to di(2-ethylhexyl) phthalate inhibits luteal function via dysregulation of CD31 and prostaglandin F2alpha in pregnant mice.

Published in:

Reproductive Biology & Endocrinology, 2015, v. 13, n. 1, p. 1, doi. 10.1186/s12958-015-0013-4

By:

Meijun Guo;
Lidan Lai;
Teng Zong;
Yan Lin;
Bei Yang;
Lu Zhang;
Mo Li;
Haibin Kuang

Publication type:

Article

Inhibition of secretory phospholipase A2 IIa attenuates prostaglandin E2-induced invasiveness in lung adenocarcinoma.

Published in:

Molecular & Cellular Biochemistry, 2019, v. 456, n. 1/2, p. 145, doi. 10.1007/s11010-019-03500-3

By:

Halpern, Alison L.;
Kohtz, Patrick D.;
Rove, Jessica Y.;
Ao, Lihua;
Meng, Xianzhong;
Fullerton, David A.;
Weyant, Michael J.

Publication type:

Article

15-deoxy-Δ12,14-Prostaglandin J2 inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism.

Published in:

Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0426-2

By:

Abis, Giancarlo;
Charles, Rebecca L.;
Kopec, Jolanta;
Yue, Wyatt W.;
Atkinson, R. Andrew;
Bui, Tam T. T.;
Lynham, Steven;
Popova, Simona;
Sun, Yin-Biao;
Fraternali, Franca;
Eaton, Philip;
Conte, Maria R.

Publication type:

Article

Anti-Inflammatory Effects by Pharmacological Inhibition or Knockdown of Fatty Acid Amide Hydrolase in BV2 Microglial Cells.

Published in:

Cells (2073-4409), 2019, v. 8, n. 5, p. 491, doi. 10.3390/cells8050491

By:

Tanaka, Mikiei;
Yagyu, Kazuya;
Sackett, Scott;
Zhang, Yumin

Publication type:

Article

Inhibition of EP4 Signaling Attenuates Aortic Aneurysm Formation.

Published in:

PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0036724

By:

Yokoyama, Utako;
Ishiwata, Ryo;
Jin, Mei-Hua;
Kato, Yuko;
Suzuki, Orie;
Jin, Huiling;
Ichikawa, Yasuhiro;
Kumagaya, Syun;
Katayama, Yuzo;
Fujita, Takayuki;
Okumura, Satoshi;
Sato, Motohiko;
Sugimoto, Yukihiko;
Aoki, Hiroki;
Suzuki, Shinichi;
Masuda, Munetaka;
Minamisawa, Susumu;
Ishikawa, Yoshihiro

Publication type:

Article

THE PROSTAGLANDIN TRANSPORTER: EICOSANOID REUPTAKE, CONTROL OF SIGNALING, AND DEVELOPMENT OF HIGH-AFFINITY INHIBITORS AS DRUG CANDIDATES.

Published in:

Transactions of the American Clinical & Climatological Association, 2015, v. 126, p. 248

By:

SCHUSTER, VICTOR L.;
YULING CHI;
RUN LU

Publication type:

Article

Prostaglandin E2 stimulates normal bronchial epithelial cell growth through induction of c-Jun and PDK1, a kinase implicated in oncogenesis.

Published in:

2015

By:

Yu Fan;
Ye Wang1;
Ke Wang;
Fan, Yu;
Wang, Ye;
Wang, Ke

Publication type:

journal article

Do aspirin and acetaminophen affect total menstrual loss?

Published in:

1984

By:

Pendergrass, Paula B.;
Ream, Larry J.;
Scott, Jane N.;
Agna, Mary A.;
Pendergrass, P B;
Ream, L J;
Scott, J N;
Agna, M A

Publication type:

journal article

Non-steroidal anti-inflammatory treatment in cancer cachexia: A systematic literature review.

Published in:

Acta Oncologica. Supplement, 2013, v. 52, n. 1, p. 6, doi. 10.3109/0284186X.2012.724536

By:

SOLHEIM, TORA S.;
FEARON, KENNETH C. H.;
BLUM, DAVID;
KAASA, STEIN

Publication type:

Article

Cancer, cachexia, prostanoids, and NSAIDs.

Published in:

2013

By:

CHRISTOFFERSEN, THORALF

Publication type:

Editorial

Ionomycin induces prostaglandin E2 formation in murine osteoblastic MC3T3-E1 cells via mechanisms independent of its ionophoric nature.

Published in:

Biochemistry & Cell Biology, 2016, v. 94, n. 3, p. 236, doi. 10.1139/bcb-2015-0148

By:

Leis, Hans Jörg;
Windischhofer, Werner

Publication type:

Article

Age-related increases in PGD(2) expression impair respiratory DC migration, resulting in diminished T cell responses upon respiratory virus infection in mice.

Published in:

2011

By:

Jincun Zhao;
Jingxian Zhao;
Legge, Kevin;
Perlman, Stanley;
Zhao, Jincun;
Zhao, Jingxian

Publication type:

journal article

Indomethacin Induction of Metamorphosis from the Asexual Stage to Sexual Stage in the Moon Jellyfish, Aurelia aurita.

Published in:

Bioscience, Biotechnology & Biochemistry, 2012, v. 76, n. 7, p. 1397, doi. 10.1271/bbb.120076

By:

KUNIYOSHI, Hisato;
OKUMURA, Izumi;
KURODA, Rie;
TSUJITA, Natsumi;
ARAKAWA, Kenji;
SHOJI, Jun;
SAITO, Tamio;
OSADA, Hiroyuki

Publication type:

Article

10T024A, a New Phenazine Derivative, as a Radical Scavenger and a Prostaglandin, Leukotriene Release Suppressor.

Published in:

Bioscience, Biotechnology & Biochemistry, 2011, v. 75, n. 10, p. 2056, doi. 10.1271/bbb.110384

By:

Komoda, Toshikazu;
Tamiya, Yuta;
Nishikawa, Masazumi

Publication type:

Article

Nonsteroidal Anti-Inflammatory Drugs Alter the Human Mesothelial Pleural Permeability via Ion Cellular Transportation by Inhibiting Prostaglandin Synthesis.

Published in:

Respiration, 2012, v. 84, n. 1, p. 62, doi. 10.1159/000336837

By:

Kouritas, Vasileios K.;
Zisis, Charalambos;
Bellenis, Ion;
Gourgoulianis, Konstantinos I.;
Molyvdas, Paschalis A.;
Hatzoglou, Chrisi

Publication type:

Article

Blood-aqueous barrier in prostaglandin EP2 receptor knockout mice.

Published in:

2002

By:

Bhattacherjee, Parimal;
Mukhopadhyay, Partha;
Tilley, Stephen L;
Koller, Beverly H;
Geoghgan, Thomas;
Paterson, Christopher A

Publication type:

journal article

A DISCUSSION ON CHEMOPREVENTION OF ORAL CANCER BY SELECTIVE CYCLOOXYGENASE-2 (COX-2) INHIBITORS.

Published in:

Digest Journal of Nanomaterials & Biostructures (DJNB), 2010, v. 5, n. 2, p. 285

By:

Singh, A. K.;
Pandey, A.;
Tewari, M.;
Prakash, Kumar;
Shukla, H. S.;
Pandey, H. P.

Publication type:

Article

CYP2C9 Involvement in ACT-453859 Metabolism.

Published in:

2015

By:

Géhin, Martine;
Dingemanse, Jasper;
Sidharta, Patricia N.

Publication type:

Letter to the Editor

First-in-Man Study of ACT-453859, a Potent CRTH2 Antagonist--Is the Metabolite Formation Influenced by a Polymorphic Enzyme?

Published in:

2015

By:

Srinivas, Nuggehally R.

Publication type:

Letter to the Editor

A novel CRTH2 antagonist: Single- and multiple-dose tolerability, pharmacokinetics, and pharmacodynamics of ACT-453859 in healthy subjects.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 7, p. 787, doi. 10.1002/jcph.478

By:

Géhin, Martine;
Strasser, Daniel S.;
Zisowsky, Jochen;
Farine, Hervé;
Groenen, Peter M.A.;
Dingemanse, Jasper;
Sidharta, Patricia N.

Publication type:

Article

Pharmacodynamics, Pharmacokinetics, and Safety of AM211: A Novel and Potent Antagonist of the Prostaglandin D2 Receptor Type 2.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 10, p. 1482, doi. 10.1177/0091270011421912

By:

Bain, G.;
King, C. D.;
Brittain, J.;
Hartung, J. P.;
DeArmond, I.;
Stearns, B.;
Truong, Y. P.;
Hutchinson, J. H.;
Evans, J. F.;
Holme, K.

Publication type:

Article

Pharmacokinetics of Laropiprant, a Selective Prostaglandin D2 Receptor 1 Antagonist, in Patients With Moderate Hepatic Impairment.

Published in:

Journal of Clinical Pharmacology, 2011, v. 51, n. 3, p. 406, doi. 10.1177/0091270010369240

By:

Wang, Ying-Hong;
Fang Liu;
Mabalot Luk, Julie Ann;
Nirula, Ajay;
Johnson-Levonas, Amy O.;
Lasseter, Kenneth C.;
Marbury, Thomas C.;
Lunde, N. Martin;
Wagner, John A.;
Lai, Eseng

Publication type:

Article

Single Therapeutic and Supratherapeutic Doses of Laropiprant, a Selective Prostaglandin D 2 Receptor 1 Antagonist, Do Not Prolong the QTcF Interval in Healthy Volunteers.

Published in:

Journal of Clinical Pharmacology, 2010, v. 50, n. 11, p. 1273, doi. 10.1177/0091270009360042

By:

Luo, Wen-Lin;
Crumley, Tami;
Ebel, David;
Atiee, George J.;
Royalty, Jane;
Johnson-Levonas, Amy O.;
Wagner, John;
Lai, Eseng

Publication type:

Article

Effects of Laropiprant, a Selective Prostaglandin D2 Receptor 1 Antagonist, on the Steady-State Pharmacokinetics of Digoxin in Healthy Adult Subjects.

Published in:

Journal of Clinical Pharmacology, 2010, v. 50, n. 7, p. 823, doi. 10.1177/0091270009356571

By:

Fang Liu;
Vessey, Laura;
Wenning, Larissa;
Connolly, Sandra;
Buckland, Melissa;
Johnson-Levonas, Amy O.;
Denker, Andrew;
Wagner, John A.;
Eseng Lai

Publication type:

Article

Potential for serotonergic agents to treat elevated intraocular pressure and glaucoma: focus on 5-HT2 receptor agonists.

Published in:

Expert Review of Ophthalmology, 2011, v. 6, n. 1, p. 105, doi. 10.1586/eop.10.69

By:

Sharif, Najam A.;
May, Jesse A.

Publication type:

Article

Unexamined Endocrine Disruption?

Published in:

Environmental Health Perspectives, 2016, v. 124, n. 4, p. A76, doi. 10.1289/ehp.124-A76

By:

Konkel, Lindsey

Publication type:

Article

Prostaglandin D2 metabolites activate asthmatic patient-derived type 2 innate lymphoid cells and eosinophils via the DP2 receptor.

Published in:

2021

By:

Carstensen, Saskia;
Gress, Christina;
Erpenbeck, Veit J.;
Kazani, Shamsah D.;
Hohlfeld, Jens M.;
Sandham, David A.;
Müller, Meike

Publication type:

journal article

Development of nonfibrotic left ventricular hypertrophy in an ANG II-induced chronic ovine hypertension model.

Published in:

Physiological Reports, 2016, v. 4, n. 17, p. n/a, doi. 10.14814/phy2.12897

By:

Klatt, Niklas;
Scherschel, Katharina;
Schad, Claudia;
Lau, Denise;
Reitmeier, Aline;
Kuklik, Pawel;
Muellerleile, Kai;
Yamamura, Jin;
Zeller, Tanja;
Steven, Daniel;
Baldus, Stephan;
Schäffer, Benjamin;
Jungen, Christiane;
Eickholt, Christian;
Wassilew, Katharina;
Schwedhelm, Edzard;
Willems, Stephan;
Meyer, Christian

Publication type:

Article

Mir526b and Mir655 Promote Tumour Associated Angiogenesis and Lymphangiogenesis in Breast Cancer.

Published in:

Cancers, 2019, v. 11, n. 7, p. 938, doi. 10.3390/cancers11070938

By:

Hunter, Stephanie;
Nault, Braydon;
Ugwuagbo, Kingsley Chukwunonso;
Maiti, Sujit;
Majumder, Mousumi

Publication type:

Article

Optimization of structures, biochemical properties of ketorolac and its degradation products based on computational studies.

Published in:

DARU: Journal of Pharmaceutical Sciences, 2019, v. 27, p. 71, doi. 10.1007/s40199-019-00243-w

By:

Uzzaman, Monir;
Uddin, Mohammad Nasir

Publication type:

Article

Piceatannol Inhibits Phorbol Ester-Induced NF-κ B Activation and COX-2 Expression in Cultured Human Mammary Epithelial Cells.

Published in:

Nutrition & Cancer, 2009, v. 61, n. 6, p. 855, doi. 10.1080/01635580903285080

By:

Liu, Dan;
Kim, Do-Hee;
Park, Jong-Min;
Na, Hye-Kyung;
Surh, Young-Joon

Publication type:

Article

Celecoxib Improves Host Defense through Prostaglandin Inhibition during Histoplasma capsulatum Infection.

Published in:

Mediators of Inflammation, 2013, v. 2013, p. 1, doi. 10.1155/2013/950981

By:

Tartari Pereira, Priscilla Aparecida;
Caetano Trindade, Bruno;
Secatto, Adriana;
Nicolete, Roberto;
Peres-Buzalaf, Camila;
Gusmão Ramos, Simone;
Sadikot, Ruxana;
da Silva Bitencourt, Claudia;
Faccioli, Lúcia Helena

Publication type:

Article

Indomethacin inhibits PGE2, regulates inflammatory response, participates in adipogenesis regulation, and improves success rate of fat transplantation in C57/B6 mice.

Published in:

Tropical Journal of Pharmaceutical Research, 2019, v. 18, n. 11, p. 2313, doi. 10.4314/tjpr.v18i11.12

By:

Hongyu Xue;
Hongyi Zhao;
Huiying Wang;
Song Zhang

Publication type:

Article

Inhibition of Lipopolysaccharide-Induced iNOS, COX- 2, and TNF-α Expression by Aqueous Extract of Orixa Japonica in RAW 264.7 Cells via Suppression of NF-κB Activity.

Published in:

Tropical Journal of Pharmaceutical Research, 2011, v. 10, n. 2, p. 161

By:

Chang-Hee Kang;
Yung H Choi;
Il-Whan Choi;
Jae-Dong Lee;
Gi-Young Kim

Publication type:

Article

Increase in meningeal blood flow by nitric oxide--interaction with calcitonin gene-related peptide receptor and prostaglandin synthesis inhibition.

Published in:

2002

By:

Strecker, T;
Dux, M;
Messlinger, K

Publication type:

journal article

Indomethacin increases the effect of isosorbide dinitrate on cerebral hemodynamic in migraine patients: pathogenetic and therapeutic implications.

Published in:

1998

By:

Castellano, AE;
Micieli, G;
Bellantonio, P;
Buzzi, MG;
Marcheselli, S;
Pompeo, F;
Rossi, F;
Nappi, G;
Castellano, A E;
Buzzi, M G

Publication type:

journal article

PPARγ as an E3 Ubiquitin-Ligase Impedes Phosphate-Stat6 Stability and Promotes Prostaglandins E2-Mediated Inhibition of IgE Production in Asthma.

Published in:

Frontiers in Immunology, 2020, v. 11, p. 1, doi. 10.3389/fimmu.2020.01224

By:

Wu, Jia;
Wang, Yan;
Zhou, Yu;
Wang, Yuqing;
Sun, Xiaowan;
Zhao, Ye;
Guan, Youfei;
Zhang, Yu;
Wang, Wei

Publication type:

Article

A Novel Multi-step Virtual Screening for the Identification of Human and Mouse mPGES-1 Inhibitors.

Published in:

Molecular Informatics, 2016, v. 35, n. 8/9, p. 358, doi. 10.1002/minf.201600024

By:

Corso, G.;
Alisi, M. A.;
Cazzolla, N.;
Coletta, I.;
Furlotti, G.;
Garofalo, B.;
Mangano, G.;
Mancini, F.;
Vitiello, M.;
Ombrato, Rosella

Publication type:

Article

Aspirin-exacerbated Respiratory Disease: A Syndrome of Mast Cell-mediated PgD2 Overproduction.

Published in:

2019

By:

Borish, Larry

Publication type:

journal article

Increased renal sodium absorption by inhibition of prostaglandin synthesis during fasting in healthy man. A possible role of the epithelialsodium channels.

Published in:

BMC Nephrology, 2010, v. 11, p. 28, doi. 10.1186/1471-2369-11-28

By:

Lauridsen, Thomas G.;
Vase, Henrik;
Starklint, Jørn;
Graffe, Carolina C.;
Bech, Jesper N.;
Nielsen, Søren;
Pedersen, Erling B.

Publication type:

Article

Intra-Pancreatic Insulin Nourishes Cancer Cells: Do Insulin-Receptor Antagonists such as PGG and EGCG Play a Role?

Published in:

American Journal of Chinese Medicine, 2020, v. 48, n. 4, p. 1005, doi. 10.1142/S0192415X20500482

By:

Hu, Lijuan;
Chen, Xijuan;
Qiu, Shuai;
Yang, Jing;
Liu, Hongyi;
Zhang, Jie;
Zhang, Dapeng;
Wang, Feng

Publication type:

Article

Indomethacin-induced inhibition of prostaglandin with hyperkalemia.

Published in:

1979

By:

Beroniade, V;
Cornielle, L;
Haraoui, B

Publication type:

Case Study

Indomethacin-induced prostaglandin inhibition with hyperkalemia. A reversible cause of hyporeninemic hypoaldosteronism.

Published in:

1979

By:

Tan, S Y;
Shapiro, R;
Franco, R;
Stockard, H;
Mulrow, P J

Publication type:

journal article

Comparison of the efficacy and adverse effects of nifedipine and indomethacin for the treatment of preterm labor

Published in:

2011

By:

Kashanian, Maryam;
Bahasadri, Shohreh;
Zolali, Bita

Publication type:

journal article