Works matching AU Tyrer, Jonathan P.

Results: 24

Using Family History Data to Improve the Power of Association Studies: Application to Cancer in UK Biobank.

Published in:

Genetic Epidemiology, 2025, v. 49, n. 1, p. 1, doi. 10.1002/gepi.22609

By:

Wilcox, Naomi;
Tyrer, Jonathan P.;
Dennis, Joe;
Yang, Xin;
Perry, John R. B.;
Gardner, Eugene J.;
Easton, Douglas F.

Publication type:

Article

Epithelial-Mesenchymal Transition (EMT) Gene Variants and Epithelial Ovarian Cancer (EOC) Risk.

Published in:

Genetic Epidemiology, 2015, v. 39, n. 8, p. 689, doi. 10.1002/gepi.21921

By:

Amankwah, Ernest K.;
Lin, Hui‐Yi;
Tyrer, Jonathan P.;
Lawrenson, Kate;
Dennis, Joe;
Chornokur, Ganna;
Aben, Katja K. H.;
Anton‐Culver, Hoda;
Antonenkova, Natalia;
Bruinsma, Fiona;
Bandera, Elisa V.;
Bean, Yukie T.;
Beckmann, Matthias W.;
Bisogna, Maria;
Bjorge, Line;
Bogdanova, Natalia;
Brinton, Louise A.;
Brooks‐Wilson, Angela;
Bunker, Clareann H.;
Butzow, Ralf

Publication type:

Article

Rare germline copy number variants (CNVs) and breast cancer risk.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-021-02990-6

By:

Dennis, Joe;
Tyrer, Jonathan P.;
Walker, Logan C.;
Michailidou, Kyriaki;
Dorling, Leila;
Bolla, Manjeet K.;
Wang, Qin;
Ahearn, Thomas U.;
Andrulis, Irene L.;
Anton-Culver, Hoda;
Antonenkova, Natalia N.;
Arndt, Volker;
Aronson, Kristan J.;
Freeman, Laura E. Beane;
Beckmann, Matthias W.;
Behrens, Sabine;
Benitez, Javier;
Bermisheva, Marina;
Bogdanova, Natalia V.;
Bojesen, Stig E.

Publication type:

Article

Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility.

Published in:

PLoS ONE, 2018, p. 1, doi. 10.1371/journal.pone.0197561

By:

Earp, Madalene;
Tyrer, Jonathan P.;
Winham, Stacey J.;
Lin, Hui-Yi;
Chornokur, Ganna;
Dennis, Joe;
Aben, Katja K. H.;
Anton-Culver, Hoda;
Antonenkova, Natalia;
Bandera, Elisa V.;
Bean, Yukie T.;
Beckmann, Matthias W.;
Bjorge, Line;
Bogdanova, Natalia;
Brinton, Louise A.;
Brooks-Wilson, Angela;
Bruinsma, Fiona;
Bunker, Clareann H.;
Butzow, Ralf;
Campbell, Ian G.

Publication type:

Article

Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0128106

By:

Chornokur, Ganna;
Lin, Hui-Yi;
Tyrer, Jonathan P.;
Lawrenson, Kate;
Dennis, Joe;
Amankwah, Ernest K.;
Qu, Xiaotao;
Tsai, Ya-Yu;
Jim, Heather S. L.;
Chen, Zhihua;
Chen, Ann Y.;
Permuth-Wey, Jennifer;
Aben, Katja KH.;
Anton-Culver, Hoda;
Antonenkova, Natalia;
Bruinsma, Fiona;
Bandera, Elisa V.;
Bean, Yukie T.;
Beckmann, Matthias W.;
Bisogna, Maria

Publication type:

Article

Copy Number Variants Are Ovarian Cancer Risk Alleles at Known and Novel Risk Loci.

Published in:

JNCI: Journal of the National Cancer Institute, 2022, v. 114, n. 11, p. 1533, doi. 10.1093/jnci/djac160

By:

DeVries, Amber A;
Dennis, Joe;
Tyrer, Jonathan P;
Peng, Pei-Chen;
Coetzee, Simon G;
Reyes, Alberto L;
Plummer, Jasmine T;
Davis, Brian D;
Chen, Stephanie S;
Dezem, Felipe Segato;
Aben, Katja K H;
Anton-Culver, Hoda;
Antonenkova, Natalia N;
Beckmann, Matthias W;
Beeghly-Fadiel, Alicia;
Berchuck, Andrew;
Bogdanova, Natalia V;
Bogdanova-Markov, Nadja;
Brenton, James D;
Butzow, Ralf

Publication type:

Article

Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer.

Published in:

2015

By:

Ramus, Susan J.;
Honglin Song;
Dicks, Ed;
Tyrer, Jonathan P.;
Rosenthal, Adam N.;
Intermaggio, Maria P.;
Fraser, Lindsay;
Gentry-Maharaj, Aleksandra;
Hayward, Jane;
Philpott, Susan;
Anderson, Christopher;
Edlund, Christopher K.;
Conti, David;
Harrington, Patricia;
Barrowdale, Daniel;
Bowtell, David D.;
Alsop, Kathryn;
Mitchell, Gillian;
Cicek, Mine S.;
Cunningham, Julie M.

Publication type:

journal article

Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk.

Published in:

Human Molecular Genetics, 2015, v. 24, n. 5, p. 1478

By:

Painter, Jodie N.;
O'Mara, Tracy A.;
Batra, Jyotsna;
Cheng, Timothy;
Lose, Felicity A.;
Dennis, Joe;
Michailidou, Kyriaki;
Tyrer, Jonathan P.;
Ahmed, Shahana;
Ferguson, Kaltin;
Healey, Catherine S.;
Kaufmann, Susanne;
Hillman, Kristine M.;
Walpole, Carina;
Moya, Leire;
Pollock, Pamela;
Jones, Angela;
Howarth, Kimberley;
Martin, Lynn;
Gorman, Maggie

Publication type:

Article

The contribution of deleterious germline mutations in BRCA1, BRCA2 and the mismatch repair genes to ovarian cancer in the population.

Published in:

Human Molecular Genetics, 2014, v. 23, n. 17, p. 4703, doi. 10.1093/hmg/ddu172

By:

Song, Honglin;
Cicek, Mine S.;
Dicks, Ed;
Harrington, Patricia;
Ramus, Susan J.;
Cunningham, Julie M.;
Fridley, Brooke L.;
Tyrer, Jonathan P.;
Alsop, Jennifer;
Jimenez-Linan, Mercedes;
Gayther, Simon A.;
Goode, Ellen L.;
Pharoah, Paul D.P.

Publication type:

Article

A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46 450 cases and 42 461 controls from the breast cancer association consortium.

Published in:

Human Molecular Genetics, 2014, v. 23, n. 7, p. 1934, doi. 10.1093/hmg/ddt581

By:

Milne, Roger L.;
Herranz, Jesús;
Michailidou, Kyriaki;
Dennis, Joe;
Tyrer, Jonathan P.;
Zamora, M. Pilar;
Arias-Perez, José Ignacio;
González-Neira, Anna;
Pita, Guillermo;
Alonso, M. Rosario;
Wang, Qin;
Bolla, Manjeet K.;
Czene, Kamila;
Eriksson, Mikael;
Humphreys, Keith;
Darabi, Hatef;
Li, Jingmei;
Anton-Culver, Hoda;
Neuhausen, Susan L.;
Ziogas, Argyrios

Publication type:

Article

A genome-wide association scan (GWAS) for mean telomere length within the COGS project: identified loci show little association with hormone-related cancer risk.

Published in:

Human Molecular Genetics, 2013, v. 22, n. 24, p. 5056, doi. 10.1093/hmg/ddt355

By:

Pooley, Karen A.;
Bojesen, Stig E.;
Weischer, Maren;
Nielsen, Sune F.;
Thompson, Deborah;
Amin Al Olama, Ali;
Michailidou, Kyriaki;
Tyrer, Jonathan P.;
Benlloch, Sara;
Brown, Judith;
Audley, Tina;
Luben, Robert;
Khaw, K-T;
Neal, David E.;
Hamdy, Freddie C.;
Donovan, Jenny L.;
Kote-Jarai, Zsofia;
Baynes, Caroline;
Shah, Mitul;
Bolla, Manjeet K.

Publication type:

Article

Characterizing somatic mutations in ovarian cancer germline risk regions.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08072-1

By:

Lai, Ping-Hung;
Tyrer, Jonathan P.;
Pharoah, Paul;
Gayther, Simon A.;
Jones, Michelle R.;
Peng, Pei-Chen

Publication type:

Article

A comprehensive gene–environment interaction analysis in Ovarian Cancer using genome‐wide significant common variants.

Published in:

International Journal of Cancer, 2019, v. 144, n. 9, p. 2192, doi. 10.1002/ijc.32029

By:

Kim, Sehee;
Wang, Miao;
Tyrer, Jonathan P.;
Jensen, Allan;
Wiensch, Ashley;
Liu, Gang;
Lee, Alice W.;
Ness, Roberta B.;
Salvatore, Maxwell;
Tworoger, Shelley S.;
Whittemore, Alice S.;
Anton‐Culver, Hoda;
Sieh, Weiva;
Olson, Sara H.;
Berchuck, Andrew;
Goode, Ellen L.;
Goodman, Marc T.;
Doherty, Jennifer Anne;
Chenevix‐Trench, Georgia;
Rossing, Mary Anne

Publication type:

Article

Shared heritability and functional enrichment across six solid cancers.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-018-08054-4

By:

Jiang, Xia;
Finucane, Hilary K.;
Schumacher, Fredrick R.;
Schmit, Stephanie L.;
Tyrer, Jonathan P.;
Han, Younghun;
Michailidou, Kyriaki;
Lesseur, Corina;
Kuchenbaecker, Karoline B.;
Dennis, Joe;
Conti, David V.;
Casey, Graham;
Gaudet, Mia M.;
Huyghe, Jeroen R.;
Albanes, Demetrius;
Aldrich, Melinda C.;
Andrew, Angeline S.;
Andrulis, Irene L.;
Anton-Culver, Hoda;
Antoniou, Antonis C.

Publication type:

Article

Author Correction: A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers.

Published in:

2021

By:

Coignard, Juliette;
Lush, Michael;
Beesley, Jonathan;
O'Mara, Tracy A.;
Dennis, Joe;
Tyrer, Jonathan P.;
Barnes, Daniel R.;
McGuffog, Lesley;
Leslie, Goska;
Bolla, Manjeet K.;
Adank, Muriel A.;
Agata, Simona;
Ahearn, Thomas;
Aittomäki, Kristiina;
Andrulis, Irene L.;
Anton-Culver, Hoda;
Arndt, Volker;
Arnold, Norbert;
Aronson, Kristan J.;
Arun, Banu K.

Publication type:

Correction Notice

A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20496-3

By:

Coignard, Juliette;
Michael Lush, Michael Lush;
Beesley, Jonathan;
O’Mara., Tracy A.;
Dennis, Joe;
Tyrer, Jonathan P.;
Barnes, Daniel R.;
McGuffog, Lesley;
Leslie, Goska;
Bolla, Manjeet K.;
Adank, Muriel A.;
Agata, Simona;
Ahearn, Thomas;
Aittomäki, Kristiina;
Andrulis, Irene L.;
Anton-Culver, Hoda;
Arndt, Volker;
Arnold, Norbert;
Aronson, Kristan J.;
Arun, Banu K.

Publication type:

Article

European polygenic risk score for prediction of breast cancer shows similar performance in Asian women.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17680-w

By:

Ho, Weang-Kee;
Tan, Min-Min;
Mavaddat, Nasim;
Tai, Mei-Chee;
Mariapun, Shivaani;
Li, Jingmei;
Ho, Peh-Joo;
Dennis, Joe;
Tyrer, Jonathan P.;
Bolla, Manjeet K.;
Michailidou, Kyriaki;
Wang, Qin;
Kang, Daehee;
Choi, Ji-Yeob;
Jamaris, Suniza;
Shu, Xiao-Ou;
Yoon, Sook-Yee;
Park, Sue K.;
Kim, Sung-Won;
Shen, Chen-Yang

Publication type:

Article

Improving on polygenic scores across complex traits using select and shrink with summary statistics (S4) and LDpred2.

Published in:

BMC Genomics, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s12864-024-10706-3

By:

Tyrer, Jonathan P.;
Peng, Pei-Chen;
DeVries, Amber A.;
Gayther, Simon A.;
Jones, Michelle R.;
Pharoah, Paul D.

Publication type:

Article

Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31.

Published in:

Nature Communications, 2013, v. 4, n. 3, p. 1627, doi. 10.1038/ncomms2613

By:

Permuth-Wey, Jennifer;
Lawrenson, Kate;
Shen, Howard C.;
Velkova, Aneliya;
Tyrer, Jonathan P.;
Chen, Zhihua;
Lin, Hui-Yi;
Ann Chen, Y;
Tsai, Ya-Yu;
Qu, Xiaotao;
Ramus, Susan J.;
Karevan, Rod;
Lee, Janet;
Lee, Nathan;
Larson, Melissa C.;
Aben, Katja K.;
Anton-Culver, Hoda;
Antonenkova, Natalia;
Antoniou, Antonis C.;
Armasu, Sebastian M.

Publication type:

Article

Publisher Correction: Shared heritability and functional enrichment across six solid cancers.

Published in:

2019

By:

Jiang, Xia;
Finucane, Hilary K.;
Schumacher, Fredrick R.;
Schmit, Stephanie L.;
Tyrer, Jonathan P.;
Han, Younghun;
Michailidou, Kyriaki;
Lesseur, Corina;
Kuchenbaecker, Karoline B.;
Dennis, Joe;
Conti, David V.;
Casey, Graham;
Gaudet, Mia M.;
Huyghe, Jeroen R.;
Albanes, Demetrius;
Aldrich, Melinda C.;
Andrew, Angeline S.;
Andrulis, Irene L.;
Anton-Culver, Hoda;
Antoniou, Antonis C.

Publication type:

Correction Notice

Consortium analysis of gene and gene-folate interactions in purine and pyrimidine metabolism pathways with ovarian carcinoma risk.

Published in:

Molecular Nutrition & Food Research, 2014, v. 58, n. 10, p. 2023, doi. 10.1002/mnfr.201400068

By:

Kelemen, Linda E.;
Terry, Kathryn L.;
Goodman, Marc T.;
Webb, Penelope M.;
Bandera, Elisa V.;
McGuire, Valerie;
Rossing, Mary Anne;
Wang, Qinggang;
Dicks, Ed;
Tyrer, Jonathan P.;
Song, Honglin;
Kupryjanczyk, Jolanta;
Dansonka‐Mieszkowska, Agnieszka;
Plisiecka‐Halasa, Joanna;
Timorek, Agnieszka;
Menon, Usha;
Gentry‐Maharaj, Aleksandra;
Gayther, Simon A.;
Ramus, Susan J.;
Narod, Steven A.

Publication type:

Article

The admixture maximum likelihood test to test for association between rare variants and disease phenotypes.

Published in:

BMC Bioinformatics, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2105-14-177

By:

Tyrer, Jonathan P.;
Guo, Qi;
Easton, Douglas F.;
Pharoah, Paul D. P.

Publication type:

Article

Association of single-nucleotide polymorphisms in the cell cycle genes with breast cancer in the British population.

Published in:

Carcinogenesis, 2008, v. 29, n. 2, p. 333, doi. 10.1093/carcin/bgm284

By:

Kristy E. Driver;
Honglin Song;
Fabienne Lesueur;
Shahana Ahmed;
Nuno L. Barbosa-Morais;
Jonathan P. Tyrer;
Bruce A.J. Ponder;
Douglas F. Easton;
Paul D.P. Pharoah;
Alison M. Dunning;
for the Studies in Epidemiology and Risks of Cancer Heredity (SEARCH) Team

Publication type:

Article

Genome-wide association analyses of ovarian cancer patients undergoing primary debulking surgery identify candidate genes for residual disease.

Published in:

NPJ Genomic Medicine, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41525-024-00395-y

By:

Ramachandran, Dhanya;
Tyrer, Jonathan P.;
Kommoss, Stefan;
DeFazio, Anna;
Riggan, Marjorie J.;
Bowtell, David;
Fereday, Sian;
Traficante, Nadia;
Hung, Jillian;
Webb, Penelope M.;
Fasching, Peter A.;
Lambrechts, Diether;
García, María J.;
Rodríguez-Antona, Cristina;
Goodman, Marc T.;
Modugno, Francesmary;
Moysich, Kirsten B.;
Karlan, Beth Y.;
Lester, Jenny;
Kjaer, Susanne K.

Publication type:

Article