Works matching AU Gu, Jijie

Results: 14

Guiding anti-RAGE monoclonal antibody development for the treatment of Alzheimer's disease via imaging

Published in:

2010

By:

Luo, Feng;
Fox, Gerard B.;
Seifert, Terese;
Chandran, Prasant;
Wu, Zhen;
Barlow, Eve;
Gu, Jijie;
Leddy, Mary;
Hsieh, Chung-Ming;
Harlan, John;
DiGianmarrino, Enrico;
Walter, Karl;
McLoughlin, Shaun;
Day, Mark;
Schoemaker, Hans;
Loebbert, Ralf;
Hahn, Alfred;
Nimmrich, Volker;
Schmidt, Martin

Publication type:

Abstract

A sequence element of p53 that determines its susceptibility to viral oncoprotein-targeted degradation.

Published in:

Oncogene, 2001, v. 20, n. 27, p. 3519, doi. 10.1038/sj.onc.1204454

By:

Gu, Jijie;
Rubin, Rachel M;
Yuan, Zhi-Min

Publication type:

Article

Rationale and development of multispecific antibody drugs.

Published in:

Expert Review of Clinical Pharmacology, 2010, v. 3, n. 4, p. 491

By:

Gu, Jijie;
Ghayur, Tariq

Publication type:

Article

A case study of a bispecific antibody manufacturability assessment and optimization during discovery stage and its implications.

Published in:

Antibody Therapeutics, 2024, v. 7, n. 3, p. 189, doi. 10.1093/abt/tbae013

By:

Wang, Shuang;
Zhang, Weijie;
Yang, Baotian;
Zhang, Xudong;
Fang, Jing;
Rui, Haopeng;
Chen, Zhijian;
Gu, Jijie;
Chen, Zhiqiang;
Xu, Jianqing

Publication type:

Article

Developability assessment at early-stage discovery to enable development of antibody-derived therapeutics.

Published in:

Antibody Therapeutics, 2023, v. 6, n. 1, p. 13, doi. 10.1093/abt/tbac029

By:

Zhang, Weijie;
Wang, Hao;
Feng, Nan;
Li, Yifeng;
Gu, Jijie;
Wang, Zhuozhi

Publication type:

Article

Biology drives the discovery of bispecific antibodies as innovative therapeutics.

Published in:

Antibody Therapeutics, 2020, v. 3, n. 1, p. 18, doi. 10.1093/abt/tbaa003

By:

Nie, Siwei;
Wang, Zhuozhi;
Moscoso-Castro, Maria;
D'Souza, Paul;
Lei, Can;
Xu, Jianqing;
Gu, Jijie

Publication type:

Article

Potent and conditional redirected T cell killing of tumor cells using Half DVD-Ig.

Published in:

Protein & Cell, 2018, v. 9, n. 1, p. 121, doi. 10.1007/s13238-017-0429-z

By:

Bardwell, Philip D.;
Staron, Matthew M.;
Liu, Junjian;
Tao, Qingfeng;
Scesney, Susanne;
Bukofzer, Gail;
Rodriguez, Luis E.;
Choi, Chee-Ho;
Wang, Jennifer;
Chang, Qing;
Dong, Feng;
Donawho, Cherrie;
Wang, Jieyi;
Grinnell, Christine M.;
Tarcsa, Edit;
Hutchins, Charles;
Ghayur, Tariq;
Gu, Jijie

Publication type:

Article

Structure reveals function of the dual variable domain immunoglobulin (DVD-Ig™) molecule.

Published in:

mAbs (1942-0862), 2013, v. 5, n. 3, p. 358, doi. 10.4161/mabs.23977

By:

Jakob, Clarissa G.;
Edalji, Rohinton;
Judge, Russell A.;
DiGiammarino, Enrico;
Yingchun Li;
Gu, Jijie;
Ghayur, Tariq

Publication type:

Article

P73 is regulated by tyrosine kinase c-Abl in the apopotic response to DNA damage.

Published in:

Nature, 1999, v. 399, n. 6738, p. 814, doi. 10.1038/21704

By:

Yuan, Zhi-Min;
Shioya, Hisashi;
Ishiko, Takatoshi;
Sun, Xiangao;
Gu, Jijie;
Huang, Yin Yin;
Lu, Hua;
Kharbanda, Surender;
Weichselbaum, Ralph;
Kufe, Donald

Publication type:

Article

Identification of Anti-EGFR and Anti-ErbB3 Dual Variable Domains Immunoglobulin (DVD-Ig) Proteins with Unique Activities.

Published in:

PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0124135

By:

Gu, Jinming;
Yang, Jinsong;
Chang, Qing;
Liu, Zhihong;
Ghayur, Tariq;
Gu, Jijie

Publication type:

Article

Identification of Anti-ErbB2 Dual Variable Domain Immunoglobulin (DVD-Ig™) Proteins with Unique Activities.

Published in:

PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0097292

By:

Gu, Jinming;
Yang, Jinsong;
Chang, Qing;
Lu, Xiaoqing;
Wang, Jieyi;
Chen, Mingjiu;
Ghayur, Tariq;
Gu, Jijie

Publication type:

Article

CRISPR/Cas9-targeting of CD40 in hematopoietic stem cells limits immune activation mediated by anti-CD40.

Published in:

PLoS ONE, 2020, v. 15, n. 3, p. 1, doi. 10.1371/journal.pone.0228221

By:

Wang, Rui;
Graham, Sean;
Sun, Ning;
McCarthy, Donna;
Peng, Ruoqi;
Erickson, Jamie;
Oconnor, Liz;
Zhu, Xiaochun;
Wurbel, Marc;
Dunstan, Robert;
Westmoreland, Susan;
Chung, Namjin;
Ghayur, Tariq;
Gu, Jijie

Publication type:

Article

Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin.

Published in:

Nature Biotechnology, 2007, v. 25, n. 11, p. 1290, doi. 10.1038/nbt1345

By:

Chengbin Wu;
Hua Ying;
Grinnell, Christine;
Bryant, Shaughn;
Miller, Renee;
Clabbers, Anca;
Bose, Sahana;
McCarthy, Donna;
Rong-Rong Zhu;
Santora, Ling;
Davis-Taber, Rachel;
Kunes, Yune;
Fung, Emma;
Schwartz, Annette;
Sakorafas, Paul;
Jijie Gu;
Tarcsa, Edit;
Murtaza, Anwar;
Ghayur, Tariq

Publication type:

Article

Molecular Basis of p53 Functional Inactivation by the Leukemic Protein MLL-ELL.

Published in:

Molecular & Cellular Biology, 2003, v. 23, n. 12, p. 4320, doi. 10.1128/MCB.23.12.4230-4246.2003

By:

Wiederschain, Dmitri;
Kawai, Hidehiko;
Gu, Jijie;
Shilatifard, Ali;
Zhi-Min Yuan

Publication type:

Article