Works matching AU Kraegen, Edward W.

Results: 51

PATHOGENESIS OF THE INSULIN RESISTANCE SYNDROME (SYNDROME X).

Published in:

Clinical & Experimental Pharmacology & Physiology, 1997, v. 24, n. 9/10, p. 782, doi. 10.1111/j.1440-1681.1997.tb02132.x

By:

Chisholm, Donald J.;
Campbell, Lesley V.;
Kraegen, Edward W.

Publication type:

Article

PPARδ agonists have opposing effects on insulin resistance in high fat-fed rats and mice due to different metabolic responses in muscle.

Published in:

2011

By:

Ye, Ji-Ming;
Tid-Ang, Jennifer;
Turner, Nigel;
Zeng, Xiao-Yi;
Li, Hai-Yan;
Cooney, Gregory J.;
Wulff, Erik Max;
Sauerberg, Per;
Kraegen, Edward W.

Publication type:

journal article

The effect of hyperinsulinemia on glucose homeostasis during moderate exercise in man.

Published in:

1982

By:

Chisholm, Donald J.;
Jenkins, Arthur B.;
James, David E.;
Kraegen, Edward W.;
Chisholm, D J;
Jenkins, A B;
James, D E;
Kraegen, E W

Publication type:

journal article

Insulin resistance due to nutrient excess.

Published in:

Cell Cycle, 2011, v. 10, n. 20, p. 3447, doi. 10.4161/cc.10.20.17886

By:

Saha, Asish K.;
Xu, X. Julia;
Balon, Thomas W.;
Brandon, Amanda;
Kraegen, Edward W.;
Ruderman, Neil B.

Publication type:

Article

Insulin Action, Regional Fat, and Myocyte Lipid: Altered Relationships with Increased Adiposity.

Published in:

Obesity (19307381), 2003, v. 11, n. 11, p. 1295, doi. 10.1038/oby.2003.176

By:

Gan, Seng Khee;
Kriketos, Adamandia D.;
Poynten, Ann M.;
Furler, Stuart M.;
Thompson, Campbell H.;
Kraegen, Edward W.;
Campbell, Lesley V.;
Chisholm, Donald J.

Publication type:

Article

Independent Influences of Central Fat and Skeletal Muscle Lipids on Insulin Sensitivity.

Published in:

Obesity (19307381), 2001, v. 9, n. 9, p. 535, doi. 10.1038/oby.2001.70

By:

Furler, Stuart M.;
Poynten, Ann M.;
Kriketos, Adamandia D.;
Lowy, Andrew J.;
Ellis, Bronwyn A.;
Maclean, Elizabeth L.;
Courtenay, Brett G.;
Kraegen, Edward W.;
Campbell, Lesley V.;
Chisholm, Donald J.

Publication type:

Article

Nutrient Excess and AMPK Downregulation in Incubated Skeletal Muscle and Muscle of Glucose Infused Rats.

Published in:

PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0127388

By:

Coughlan, Kimberly A.;
Balon, Thomas W.;
Valentine, Rudy J.;
Petrocelli, Robert;
Schultz, Vera;
Brandon, Amanda;
Cooney, Gregory J.;
Kraegen, Edward W.;
Ruderman, Neil B.;
Saha, Asish K.

Publication type:

Article

Overexpression of SIRT1 in Rat Skeletal Muscle Does Not Alter Glucose Induced Insulin Resistance.

Published in:

PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0121959

By:

Brandon, Amanda E.;
Tid-Ang, Jennifer;
Wright, Lauren E.;
Stuart, Ella;
Suryana, Eurwin;
Bentley, Nicholas;
Turner, Nigel;
Cooney, Gregory J.;
Ruderman, Neil B.;
Kraegen, Edward W.

Publication type:

Article

Activation of AMPK by Bitter Melon Triterpenoids Involves CaMKKβ.

Published in:

PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0062309

By:

Iseli, Tristan J.;
Turner, Nigel;
Zeng, Xiao-Yi;
Cooney, Gregory J.;
Kraegen, Edward W.;
Yao, Sheng;
Ye, Yang;
James, David E.;
Ye, Ji-Ming

Publication type:

Article

Oleanolic Acid Reduces Hyperglycemia beyond Treatment Period with Akt/FoxO1-Induced Suppression of Hepatic Gluconeogenesis in Type-2 Diabetic Mice.

Published in:

PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0042115

By:

Xiao-Yi Zeng;
Yi-Ping Wang;
James Cantley;
Iseli, Tristan J.;
Molero, Juan Carlos;
Hegarty, Bronwyn D.;
Kraegen, Edward W.;
Yang Ye;
Ji-Ming Ye

Publication type:

Article

Differing Endoplasmic Reticulum Stress Response to Excess Lipogenesis versus Lipid Oversupply in Relation to Hepatic Steatosis and Insulin Resistance.

Published in:

PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0030816

By:

Lu-Ping Ren;
Chan, Stanley M. H.;
Xiao-Yi Zeng;
Laybutt, D. Ross;
Iseli, Tristan J.;
Ruo-Qiong Sun;
Kraegen, Edward W.;
Cooney, Gregory J.;
Turner, Nigel;
Ji-Ming Ye

Publication type:

Article

Changes in Aerobic Capacity and Visceral Fat but not Myocyte Lipid Levels Predict Increased Insulin Action After Exercise in Overweight and Obese Men.

Published in:

Diabetes Care, 2003, v. 26, n. 6, p. 1706, doi. 10.2337/diacare.26.6.1706

By:

Seng Khee Gan;
Kriketos, Adamandia D.;
Ellis, Bronwyn A.;
Thompson, Campbell H.;
Kraegen, Edward W.;
Chisholm, Donald J.

Publication type:

Article

The Determinants of Glycemic Responses to Diet Restriction and Weight Loss in Obesity and NIDDM.

Published in:

Diabetes Care, 1998, v. 21, n. 5, p. 687, doi. 10.2337/diacare.21.5.687

By:

Markovic, Tania P.;
Jenkins, Arthur B.;
Campbell, Lesley V.;
Furler, Stuart M.;
Kraegen, Edward W.;
Chisholm, Donald J.

Publication type:

Article

Assessment of experts' approach to insulin therapy and development of a simulator for diabetes insulin adjustment.

Published in:

1992

By:

Hauser, Thomas;
Kraegen, Edward W.;
Campbell, Lesley V.;
Compton, Paul J.;
Sammut, Claude;
Chisholm, Donald J.;
Hauser, T;
Kraegen, E W;
Campbell, L V;
Compton, P J;
Sammut, C;
Chisholm, D J

Publication type:

journal article

Blood glucose control by intermittent loop closure in the basal mode: computer simulation studies with a diabetic model.

Published in:

1985

By:

Furler, Stuart M.;
Kraegen, Edward W.;
Smallwood, Robert H.;
Chisholm, Donald J.;
Furler, S M;
Kraegen, E W;
Smallwood, R H;
Chisholm, D J

Publication type:

journal article

Comparison of plateau insulin levels achieved by intravenous or subcutaneous insulin infusion: evidence for low rates of subcutaneous degradation.

Published in:

1983

By:

KRAEGEN, EDWARD W.;
CHISHOLM, DONALD J.;
HEWETT, MARGOT J.;
Kraegen, E W;
Chisholm, D J;
Hewett, M J

Publication type:

journal article

Overexpression of Carnitine Palmitoyltransferase-1 in Skeletal Muscle Is Sufficient to Enhance Fatty Acid Oxidation and Improve High-Fat Diet-Induced Insulin Resistance.

Published in:

Diabetes, 2009, v. 58, n. 3, p. 550, doi. 10.2337/db08-1078

By:

Bruce, Clinton R.;
Hoy, Andrew J.;
Turner, Nigel;
Watt, Matthew J.;
Allen, Tamara L.;
Carpenter, Kevin;
Cooney, Gregory J.;
Febbraio, Mark A.;
Kraegen, Edward W.

Publication type:

Article

Fat partitioning and insulin sensitivity: robbing Peter to pay Paul?

Published in:

2009

By:

Watt MJ;
Kraegen EW;
Watt, Matthew J;
Kraegen, Edward W

Publication type:

journal article

Fat Partitioning and Insulin Sensitivity.

Published in:

2009

By:

Watt, Matthew J.;
Kraegen, Edward W.

Publication type:

Editorial

Berberine and Its More Biologically Available Derivative, Dihydroberberine, Inhibit Mitochondrial Respiratory Complex I.

Published in:

Diabetes, 2008, v. 57, n. 5, p. 1414, doi. 10.2337/db07-1552

By:

Turner, Nigel;
Jing-Ya Li;
Gosby, Alison;
To, Sabrina W. C.;
Zhe Cheng;
Miyoshi, Hiroyuki;
Taketo, Makoto M.;
Cooney, Gregory J.;
Kraegen, Edward W.;
James, David E.;
Li-Hong Hu;
Jia Li;
Ye, Ji-Ming

Publication type:

Article

Insulin Resistance in Rat Skeletal Muscle Induced by Acute Glucose Infusion Is Not Dependent on Oxidative Stress.

Published in:

Diabetes, 2007, v. 56, p. A341

By:

Hoy, Andrew J.;
Bruce, Clinton R.;
Turner, Nigel;
James, David E.;
Cooney, Gregory J.;
Kraegen, Edward W.

Publication type:

Article

Acute Glucose Infusion-Induced Insulin Resistance Occurs Independent of Defects in Insulin Signaling in Skeletal Muscle.

Published in:

Diabetes, 2007, v. 56, p. A341

By:

Hoy, Andrew J.;
Bruce, Clinton R.;
Cederberg, Anna;
Turner, Nigel;
James, David E.;
Cooney, Gregory J.;
Kraegen, Edward W.

Publication type:

Article

Berberine Activates AMPK in L6 Myotubes by a Mechanism Other Than Via Changes in ATP Levels.

Published in:

Diabetes, 2007, v. 56, p. A164

By:

Turner, Nigel;
To, Sabrina;
Gosby, Alison;
Kraegen, Edward W.;
James, David E.;
Cooney, Gregory J.

Publication type:

Article

Berberine, a Natural Plant Product, Activates AMP-Activated Protein Kinase With Beneficial Metabolic Effects in Diabetic and Insulin-Resistant States.

Published in:

Diabetes, 2006, v. 55, n. 8, p. 2256, doi. 10.2337/db06-0006

By:

Lee, Yun S.;
Kim, Woo S.;
Kim, Kang H.;
Yoon, Myung J.;
Cho, Hye J.;
Shen, Yun;
Ye, Ji-Ming;
Lee, Chul H.;
Oh, Won K.;
Kim, Chul T.;
Hohnen-Behrens, Cordula;
Gosby, Alison;
Kraegen, Edward W.;
James, David E.;
Kim, Jae B.

Publication type:

Article

Acute bidirectional manipulation of muscle glucose uptake by in vivo electrotransfer of constructs targeting glucose transporter genes.

Published in:

2005

By:

Cleasby, Mark E.;
Davey, Jonathan R.;
Reinten, Tracie A.;
Graham, Michael W.;
James, David E.;
Kraegen, Edward W.;
Cooney, Gregory J.

Publication type:

journal article

Metformin prevents the development of acute lipid-induced insulin resistance in the rat through altered hepatic signaling mechanisms.

Published in:

2004

By:

Cleasby, Mark E.;
Dzamko, Nicolas;
Hegarty, Bronwyn D.;
Cooney, Gregory J.;
Kraegen, Edward W.;
Ye, Ji-Ming

Publication type:

journal article

AMP-activated protein kinase activation by AICAR increases both muscle fatty acid and glucose uptake in white muscle of insulin-resistant rats in vivo.

Published in:

2004

By:

Iglesias, Miguel A.;
Furler, Stuart M.;
Cooney, Gregory J.;
Kraegen, Edward W.;
Ji-Ming Ye;
Ye, Ji-Ming

Publication type:

journal article

Altered myocellular and abdominal fat partitioning predict disturbance in insulin action in HIV protease inhibitor-related lipodystrophy.

Published in:

2002

By:

Gan, Seng Khee;
Samaras, Katherine;
Thompson, Campbell H.;
Kraegen, Edward W.;
Carr, Andrew;
Cooper, David A.;
Chisholm, Donald J.

Publication type:

journal article

AICAR administration causes an apparent enhancement of muscle and liver insulin action in insulin-resistant high-fat-fed rats.

Published in:

2002

By:

Iglesias, Miguel A.;
Ye, Ji-Ming;
Frangioudakis, Georgia;
Saha, Asish K.;
Tomas, Eva;
Ruderman, Neil B.;
Cooney, Gregory J.;
Kraegen, Edward W.

Publication type:

journal article

Increased efficiency of fatty acid uptake contributes to lipid accumulation in skeletal muscle of high fat-fed insulin-resistant rats.

Published in:

2002

By:

Hegarty, Bronwyn D;
Cooney, Gregory J.;
Kraegen, Edward W.;
Furler, Stuart M.

Publication type:

journal article

Chronic central melanocortin-4 receptor antagonism and central neuropeptide-Y infusion in rats produce increased adiposity by divergent pathways.

Published in:

2002

By:

Baran, Katherine;
Preston, Elaine;
Wilks, Donna;
Cooney, Gregory J.;
Kraegen, Edward W.;
Sainsbury, Amanda

Publication type:

journal article

Alteration in Phosphorylation of P20 Is Associated With Insulin Resistance.

Published in:

Diabetes, 2001, v. 50, n. 8, p. 1821, doi. 10.2337/diabetes.50.8.1821

By:

Yu Wang;
Aimin Xu;
Jiming Ye;
Kraegen, Edward W.;
Tse, Cynthia A.;
Cooper, Garth J.S.

Publication type:

Article

Peroxisome Proliferator-Activated Receptor (PPAR)-α Activation Lowers Muscle Lipids and Improves Insulin Sensitivity in High Fat-Fed Rats.

Published in:

Diabetes, 2001, v. 50, n. 2, p. 411

By:

Ji-Ming Ye;
Doyle, Patrick J.;
Iglesias, Miguel A.;
Watson, David G.;
Cooney, Gregory J.;
Kraegen, Edward W.

Publication type:

Article

Local factors modulate tissue-specific NEFA utilization: assessment in rats using 3H-(R)-2-bromopalmitate.

Published in:

2000

By:

Furler, Stuart M.;
Cooney, Gregory J.;
Hegarty, Bronwyn D.;
Lim-Fraser, Megan Y.;
Kraegen, Edward W.;
Oakes, Nicholas D.;
Furler, S M;
Cooney, G J;
Hegarty, B D;
Lim-Fraser, M Y;
Kraegen, E W;
Oakes, N D

Publication type:

journal article

Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade.

Published in:

1999

By:

Griffin, Margaret E.;
Marcucci, Melissa J.;
Cline, Gary W.;
Bell, Kim;
Barucci, Nicole;
Lee, Dennis;
Goodyear, Laurie J.;
Kraegen, Edward W.;
White, Morris F.;
Shulman, Gerald I.;
Griffin, M E;
Marcucci, M J;
Cline, G W;
Bell, K;
Barucci, N;
Lee, D;
Goodyear, L J;
Kraegen, E W;
White, M F;
Shulman, G I

Publication type:

journal article

Diet-induced muscle insulin resistance in rats is ameliorated by acute dietary lipid withdrawal or a single bout of exercise: parallel relationship between insulin stimulation of glucose uptake and suppression of long-chain fatty acyl-CoA.

Published in:

1997

By:

Oakes, Nicholas D.;
Bell, Kiln S.;
Furler, Stuart M.;
Camilleri, Souad;
Saha, Asish K.;
Ruderman, Neff B.;
Chisholm, Donald J.;
Kraegen, Edward W.;
Oakes, N D;
Bell, K S;
Furler, S M;
Camilleri, S;
Saha, A K;
Ruderman, N B;
Chisholm, D J;
Kraegen, E W

Publication type:

journal article

Mechanisms of liver and muscle insulin resistance induced by chronic high-fat feeding.

Published in:

1997

By:

Oakes, Nicholas D.;
Cooney, Gregory J.;
Camilleri, Souad;
Chisholm, Donald J.;
Kraegen, Edward W.;
Oakes, N D;
Cooney, G J;
Camilleri, S;
Chisholm, D J;
Kraegen, E W

Publication type:

journal article

Alterations in the expression and cellular localization of protein kinase C isozymes epsilon and theta are associated with insulin resistance in skeletal muscle of the high-fat-fed rat.

Published in:

1997

By:

Schmitz-Peiffer, Carsten;
Browne, Carol L.;
Oakes, Nicholas D.;
Watkinson, Allan;
Chisholm, Donald J.;
Kraegen, Edward W.;
Biden, Trevor J.;
Schmitz-Peiffer, C;
Browne, C L;
Oakes, N D;
Watkinson, A;
Chisholm, D J;
Kraegen, E W;
Biden, T J

Publication type:

journal article

Growth hormone-induced insulin resistance and its relationship to lipid availability in the rat.

Published in:

1996

By:

Hettiarachchi, Manthinda;
Watkinson, Allan;
Jenkins, Arthur B.;
Theos, Vicki;
Ho, Ken K.Y.;
Kraegen, Edward W.;
Hettiarachchi, M;
Watkinson, A;
Jenkins, A B;
Theos, V;
Ho, K K;
Kraegen, E W

Publication type:

journal article

A new antidiabetic agent, BRL 49653, reduces lipid availability and improves insulin action and glucoregulation in the rat.

Published in:

1994

By:

Oakes, Nicholas D.;
Kennedy, Catherine J.;
Jenkins, Arthur B.;
Laybutt, D. Ross;
Chisholm, Donald J.;
Kraegen, Edward W.;
Oakes, N D;
Kennedy, C J;
Jenkins, A B;
Laybutt, D R;
Chisholm, D J;
Kraegen, E W

Publication type:

journal article

Development of muscle insulin resistance after liver insulin resistance in high-fat-fed rats.

Published in:

1991

By:

Kraegen, Edward W.;
Clark, Peter W.;
Jenkins, Arthur B.;
Daley, Eugene A.;
Chisholm, Donald J.;
Storlien, Leonard H.;
Kraegen, E W;
Clark, P W;
Jenkins, A B;
Daley, E A;
Chisholm, D J;
Storlien, L H

Publication type:

journal article

Influence of dietary fat composition on development of insulin resistance in rats. Relationship to muscle triglyceride and omega-3 fatty acids in muscle phospholipid.

Published in:

1991

By:

Storlien, Leonard H.;
Jenkins, Arthur B.;
Chisholm, Donald J.;
Pascoe, Wendy S.;
Khouri, Sue;
Kraegen, Edward W.;
Storlien, L H;
Jenkins, A B;
Chisholm, D J;
Pascoe, W S;
Khouri, S;
Kraegen, E W

Publication type:

journal article

Effects of exercise training and dietary manipulation on insulin-regulatable glucose-transporter mRNA in rat muscle.

Published in:

1991

By:

Wake, Samantha A.;
Sowden, Judith A.;
Storlien, Leonard H.;
James, David E.;
Clark, Peter W.;
Shine, John;
Chisholm, Donald J.;
Kraegen, Edward W.;
Wake, S A;
Sowden, J A;
Storlien, L H;
James, D E;
Clark, P W;
Shine, J;
Chisholm, D J;
Kraegen, E W

Publication type:

journal article

Effects of fish oil supplementation on glucose and lipid metabolism in NIDDM.

Published in:

1989

By:

Borkman, Mark;
Chisholm, Donald J.;
Furler, Stuart M.;
Storlien, Leonard H.;
Kraegen, Edward W.;
Simon, Leon A.;
Chesterman, Colin N.;
Borkman, M;
Chisholm, D J;
Furler, S M;
Storlien, L H;
Kraegen, E W;
Simons, L A;
Chesterman, C N

Publication type:

journal article

Effect of d-fenfluramine on basal glucose turnover and fat-feeding-induced insulin resistance in rats.

Published in:

1989

By:

Storlien, Leonard H.;
Thorburn, Anne W.;
Smythe, George A.;
Jenkins, Arthur B.;
Chisholm, Donald J.;
Kraegen, Edward W.;
Storlien, L H;
Thorburn, A W;
Smythe, G A;
Jenkins, A B;
Chisholm, D J;
Kraegen, E W

Publication type:

journal article

Physiological importance of deficiency in early prandial insulin secretion in non-insulin-dependent diabetes.

Published in:

1988

By:

Bruce, David G.;
Chisholm, Donald J.;
Storlien, Leonard H.;
Kraegen, Edward W.;
Bruce, D G;
Chisholm, D J;
Storlien, L H;
Kraegen, E W

Publication type:

journal article

ROUTINE USE OF LOW‐DOSE INTRAVENOUS INSULIN INFUSION IN SEVERE HYPERGLYCAEMIA∗.

Published in:

Medical Journal of Australia, 1976, v. 2, n. 14, p. 519, doi. 10.5694/j.1326-5377.1976.tb128205.x

By:

Campbell, Lesley V.;
Lazarus, Leslie;
Casey, John H.;
Kraegen, Edward W.

Publication type:

Article

Programming of insulin delivery with meals during subcutaneous insulin infusion.

Published in:

1981

By:

CHISHOLM, DONALD J.;
KRAEGEN, EDWARD W.;
ZELENKA, GUIDO S.;
Chisholm, D J;
Kraegen, E W;
Zelenka, G S

Publication type:

journal article

Downregulation of AMPK Accompanies Leucine- and Glucose-Induced Increases in Protein Synthesis and Insulin Resistance in Rat Skeletal Muscle.

Published in:

Diabetes, 2010, v. 59, n. 10, p. 2426, doi. 10.2337/db09-1870

By:

Saha, Asish K.;
Xu, X. Julia;
Lawson, Ebony;
Deoliveira, Rosangela;
Brandon, Amanda E.;
Kraegen, Edward W.;
Ruderman, Neff B.

Publication type:

Article

Enhancement of Muscle Mitochondrial Oxidative Capacity and Alterations in Insulin Action Are Lipid Species Dependent.

Published in:

Diabetes, 2009, v. 58, n. 11, p. 2547, doi. 10.2337/db09-0784

By:

Turner, Nigel;
Hariharan, Krit;
TidAng, Jennifer;
Frangioudakis, Georgia;
Beale, Susan M.;
Wright, Lauren E.;
Xiao Yi Zeng;
Leslie, Simon J.;
Jing-Ya Li;
Kraegen, Edward W.;
Cooney, Gregory J.;
Ji-Ming Ye

Publication type:

Article