Works matching DE "RAP1 proteins"

Results: 51

Rif1 prolongs the embryonic S phase at the Drosophila mid-blastula transition.

Published in:

2018

By:

Seller, Charles A.;
O’Farrell, Patrick H.

Publication type:

Abstract

Rap1 helps endothelial cells stay close.

Published in:

Journal of Cell Biology, 2013, v. 202, n. 6, p. 828, doi. 10.1083/jcb.2026iti2

By:

Leslie, Mitch

Publication type:

Article

Rap1 potentiates endothelial cell junctions by spatially controlling myosin II activity and actin organization.

Published in:

Journal of Cell Biology, 2013, v. 202, n. 6, p. 901, doi. 10.1083/jcb.201301115

By:

Koji Ando;
Shigetomo Fukuhara;
Takahiro Moriya;
Yutaro Obara;
Norimichi Nakahata;
Naoki Mochizuki

Publication type:

Article

Distinct signaling mechanisms regulate migration in unconfined versus confined spaces.

Published in:

Journal of Cell Biology, 2013, v. 202, n. 5, p. 807, doi. 10.1083/jcb.201302132

By:

Wei-Chien Hung;
Shih-Hsun Chen;
Paul, Colin D.;
Stroka, Kimberly M.;
Ying-Chun Lo;
Yang, Joy T.;
Konstantopoulos, Konstantinos

Publication type:

Article

The adaptor molecule RIAM integrates signaling events critical for integrin-mediated control of immune function and cancer progression.

Published in:

Science Signaling, 2017, v. 10, n. 493, p. 1, doi. 10.1126/scisignal.aam8298

By:

Patsoukis, Nikolaos;
Bardhan, Kankana;
Sari, Duygu;
Lequn Li;
Strauss, Laura;
Boussiotis, Vassiliki A.;
Weaver, Jessica D.;
Torres-Gomez, Alvaro;
Lafuente, Esther M.

Publication type:

Article

Identification and Characterization of the Entamoeba Histolytica Rab8a Binding Protein: A Cdc50 Homolog.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 12, p. 3831, doi. 10.3390/ijms19123831

By:

Hanadate, Yuki;
Saito-Nakano, Yumiko;
Nakada-Tsukui, Kumiko;
Nozaki, Tomoyoshi

Publication type:

Article

RAP1-GTPase signaling and platelet function.

Published in:

Journal of Molecular Medicine, 2016, v. 94, n. 1, p. 13, doi. 10.1007/s00109-015-1346-3

By:

Stefanini, Lucia;
Bergmeier, Wolfgang

Publication type:

Article

Rab5 and Alsin regulate stress-activated cytoprotective signaling on mitochondria.

Published in:

eLife, 2018, p. 1, doi. 10.7554/eLife.32282

By:

FoSheng Hsu;
Spannl, Stephanie;
Ferguson, Charles;
Hyman, Anthony A.;
Parton, Robert G.;
Zerial, Marino

Publication type:

Article

Molecular mechanism to target the endosomal Mon1-Ccz1 GEF complex to the pre-autophagosomal structure.

Published in:

eLife, 2018, p. 1, doi. 10.7554/eLife.31145

By:

Jieqiong Gao;
Langemeyer, Lars;
Kümmel, Daniel;
Reggiori, Fulvio;
Ungermann, Christian

Publication type:

Article

Rac1-mediated membrane raft localization of PI3K/p110β is required for its activation by GPCRs or PTEN loss.

Published in:

eLife, 2016, p. 1, doi. 10.7554/eLife.17635

By:

Cizmecioglu, Onur;
Jing Ni;
Shaozhen Xie;
Zhao, Jean J.;
Roberts, Thomas M.

Publication type:

Article

Publisher Correction: Localization of RalB signaling at endomembrane compartments and its modulation by autophagy.

Published in:

2019

By:

Singh, Manish Kumar;
Martin, Alexandre P. J.;
Joffre, Carine;
Zago, Giulia;
Camonis, Jacques;
Coppey, Mathieu;
Parrini, Maria Carla

Publication type:

Correction Notice

Knockdown of PRL-3 increases mitochondrial superoxide anion production through transcriptional regulation of RAP1.

Published in:

Cancer Management & Research, 2018, v. 10, p. 5071, doi. 10.2147/CMAR.S165344

By:

Yang, Yongyong;
Lian, Shenyi;
Meng, Lin;
Tian, Zhihua;
Feng, Qin;
Wang, Yue;
Wang, Ping;
Qu, Like;
Shou, Chengchao

Publication type:

Article

The Racl Inhibitor NSC23766 Suppresses CREB Signaling by Targeting NMDA Receptor Function.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 42, p. 14006, doi. 10.1523/JNEUROSCI.1659-14.2014

By:

Hailong Hou;
Chávez, Andrés E.;
Chih-Chieh Wang;
Hongtian Yang;
Hua Gu;
Siddoway, Benjamin A.;
Hall, Benjamin J.;
Castillo, Pablo E.;
Xia, Houhui

Publication type:

Article

SILAC-based phosphoproteomics reveals an inhibitory role of KSR1 in p53 transcriptional activity via modulation of DBC1.

Published in:

British Journal of Cancer, 2013, v. 109, n. 10, p. 2675, doi. 10.1038/bjc.2013.628

By:

Zhang, H;
Xu, Y;
Filipovic, A;
Lit, L C;
Koo, C-Y;
Stebbing, J;
Giamas, G

Publication type:

Article

Testis-Specific GTPase (TSG): An oligomeric protein.

Published in:

BMC Genomics, 2016, v. 17, p. 1, doi. 10.1186/s12864-016-3145-9

By:

Sudeep Kumar;
Hyun Joo Lee;
Park, Hee-Sae;
Keesook Lee

Publication type:

Article

Expression and function of Rac1 in the nucleus accumbens of rats with chronic stress depression.

Published in:

Journal of Hainan Medical University, 2019, v. 25, n. 20, p. 15

By:

Bao-Ling;
Xiao-Hua Hu;
Zong-Qin Wang;
Zuo-Hui Gao;
Ying-ying Feng

Publication type:

Article

Development and evaluation of specific PCR and LAMP assays for the rapid detection of Phytophthora melonis.

Published in:

European Journal of Plant Pathology, 2013, v. 137, n. 3, p. 597, doi. 10.1007/s10658-013-0273-9

By:

Chen, Qinghe;
Li, Benjin;
Liu, Peiqing;
Lan, Chengzhong;
Zhan, Zhixiong;
Weng, Qiyong

Publication type:

Article

MACROD1/LRP16 Enhances LPS-Stimulated Inflammatory Responses by Up-Regulating a Rac1-Dependent Pathway in Adipocytes.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2018, v. 51, n. 6, p. 2591, doi. 10.1159/000495931

By:

Zang, Li;
Yang, Guoqing;
Gu, Weijun;
Wang, Anping;
Dou, Jingtao;
Mu, Yiming;
Lyu, Zhaohui;
Hong, Quan;
Wu, Di

Publication type:

Article

Downregulation of RIF1 Enhances Sensitivity to Platinum-Based Chemotherapy in Epithelial Ovarian Cancer (EOC) by Regulating Nucleotide Excision Repair (NER) Pathway.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2018, v. 46, n. 5, p. 1971, doi. 10.1159/000489418

By:

Yong-Bin Liu;
Ying Mei;
Zheng-Wen Tian;
Jing Long;
Chen-Hui Luo;
Hong-Hao Zhou

Publication type:

Article

The downregulation of Rap1 GTPase-activating protein is associated with a poor prognosis in colorectal cancer and may impact on tumor progression.

Published in:

Oncology Letters, 2018, v. 15, n. 5, p. 7661, doi. 10.3892/ol.2018.8305

By:

Gao, Wei-Li;
Ye, Guo-Chao;
Liu, Li-Wei;
Wei, Lu

Publication type:

Article

Ras-related protein Rap2c promotes the migration and invasion of human osteosarcoma cells.

Published in:

Oncology Letters, 2018, v. 15, n. 4, p. 5352, doi. 10.3892/ol.2018.7987

By:

Wu, Jinxia;
Du, Wenqi;
Wang, Xiucun;
Wei, Lulu;
Pan, Yaojie;
Wu, Xiaojin;
Zhang, Jinling;
Pei, Dongsheng

Publication type:

Article

Dynamic expression of Epac and Rap1 in mouse oocytes and preimplantation embryos.

Published in:

Experimental & Therapeutic Medicine, 2018, v. 16, n. 2, p. 523, doi. 10.3892/etm.2018.6253

By:

Wang, Jun-Chao;
Geng, Ying;
Han, Ying;
Luo, Hai-Ning;
Zhang, Yun-Shan

Publication type:

Article

MiR-4763-3p targeting RASD2 as a Potential Biomarker and Therapeutic Target for Schizophrenia.

Published in:

Aging & Disease, 2022, v. 13, n. 4, p. 1278, doi. 10.14336/AD.2022.0103

By:

Jiao Wang;
Wenxin Qi;
Hongwei Shi;
Lin Huang;
Fujiang Ning;
Fushuai Wang;
Kai Wang;
Haotian Bai;
Hao Wu;
Junyi Zhuang;
Huanle Hong;
Haicong Zhou;
Hu Feng;
Yinping Zhou;
Naijun Dong;
Li Liu;
Yanyan Kong;
Jiang Xie;
Chunhua Zhao, Robert

Publication type:

Article

Rac1 is dispensable for oocyte maturation and female fertility in vivo.

Published in:

PLoS ONE, 2017, v. 12, n. 5, p. 1, doi. 10.1371/journal.pone.0177202

By:

Hao, Jian-Xiu;
Meng, Tie-Gang;
Fan, Li-Hua;
Yao, Yuan-Qing

Publication type:

Article

Dynamin2 controls Rap1 activation and integrin clustering in human T lymphocyte adhesion.

Published in:

PLoS ONE, 2017, v. 12, n. 3, p. 1, doi. 10.1371/journal.pone.0172443

By:

Eppler, Felix J.;
Quast, Thomas;
Kolanus, Waldemar

Publication type:

Article

Rac1 plays an essential role in axon growth and guidance and in neuronal survival in the central and peripheral nervous systems.

Published in:

Neural Development, 2015, v. 10, p. 1, doi. 10.1186/s13064-015-0049-3

By:

Hua, Zhong L.;
Emiliani, Francesco E.;
Nathans, Jeremy

Publication type:

Article

Tissue-based quantitative proteome analysis of human hepatocellular carcinoma using tandem mass tags.

Published in:

Biomarkers, 2017, v. 22, n. 2, p. 113, doi. 10.1080/1354750X.2016.1210678

By:

Megger, Dominik Andre;
Rosowski, Kristin;
Ahrens, Maike;
Bracht, Thilo;
Eisenacher, Martin;
Schlaak, Jörg F.;
Weber, Frank;
Hoffmann, Andreas-Claudius;
Meyer, Helmut E.;
Baba, Hideo A.;
Sitek, Barbara

Publication type:

Article

Regulation of RabGAPs involved in insulin action.

Published in:

Biochemical Society Transactions, 2018, v. 46, n. 3, p. 683, doi. 10.1042/BST20170479

By:

Mafakheri, Samaneh;
Chadt, Alexandra;
Al-Hasani, Hadi

Publication type:

Article

Modulation of actin dynamics by Rac1 to target cognitive function.

Published in:

Journal of Neurochemistry, 2015, v. 133, n. 6, p. 767, doi. 10.1111/jnc.13100

By:

Tejada‐Simon, Maria V.

Publication type:

Article

Rap1A promotes ovarian cancer metastasis via activation of ERK/p38 and notch signaling.

Published in:

Cancer Medicine, 2016, v. 5, n. 12, p. 3544, doi. 10.1002/cam4.946

By:

Lu, Lili;
Wang, Jingshu;
Wu, Yougen;
Wan, Ping;
Yang, Gong

Publication type:

Article

Genome analysis of American minks reveals link of mutations in Ras-related protein-38 gene to Moyle brown coat phenotype.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-72239-5

By:

Manakhov, Andrey D.;
Mintseva, Maria Yu.;
Andreev, Igor A.;
Uralsky, Lev I.;
Andreeva, Tatiana V.;
Trapezov, Oleg V.;
Rogaev, Evgeny I.

Publication type:

Article

EGFR-dependent pancreatic carcinoma cell metastasis through Rap1 activation.

Published in:

Oncogene, 2012, v. 31, n. 22, p. 2783, doi. 10.1038/onc.2011.450

By:

Huang, M;
Anand, S;
Murphy, E A;
Desgrosellier, J S;
Stupack, D G;
Shattil, S J;
Schlaepfer, D D;
Cheresh, D A

Publication type:

Article

Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapy.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-13082-9

By:

Khattar, Ekta;
Maung, Kyaw Ze Ya;
Chew, Chen Li;
Ghosh, Arkasubhra;
Mok, Michelle Meng Huang;
Lee, Pei;
Zhang, Jun;
Chor, Wei Hong Jeff;
Cildir, Gökhan;
Wang, Chelsia Qiuxia;
Mohd-Ismail, Nur Khairiah;
Chin, Desmond Wai Loon;
Lee, Soo Chin;
Yang, Henry;
Shin, Yong-Jae;
Nam, Do-Hyun;
Chen, Liming;
Kumar, Alan Prem;
Deng, Lih Wen;
Ikawa, Masahito

Publication type:

Article

Intrinsic GTP hydrolysis is observed for a switch 1 variant of Cdc42 in the presence of a specific GTPase inhibitor.

Published in:

Small GTPases, 2016, v. 7, n. 1, p. 1, doi. 10.1080/21541248.2015.1123797

By:

Morris, Kyla M.;
Henderson, Rory;
Suresh Kumar, Thallapuranam Krishnaswamy;
Heyes, Colin D.;
Adams, Paul D.

Publication type:

Article

Loss of RAP2A Aggravates Cartilage Degradation in TMJOA via YAP Signaling.

Published in:

Journal of Dental Research, 2023, v. 102, n. 3, p. 302, doi. 10.1177/00220345221132213

By:

Qi, H.;
Zhang, Y.;
Xu, L.;
Zheng, X.;
Li, Y.;
Wei, Q.;
Zhao, Z.;
Fang, J.

Publication type:

Article

Rab5a-mediated autophagy regulates the phenotype and behavior of vascular smooth muscle cells.

Published in:

Molecular Medicine Reports, 2016, v. 14, n. 5, p. 4445, doi. 10.3892/mmr.2016.5774

By:

JIN-YUN TAN;
LUO-QI JIA;
WEI-HAO SHI;
QING HE;
LEI ZHU;
BO YU

Publication type:

Article

HMGB1 promotes cellular chemokine synthesis and potentiates mesenchymal stromal cell migration via Rap1 activation.

Published in:

Molecular Medicine Reports, 2016, v. 14, n. 2, p. 1283, doi. 10.3892/mmr.2016.5398

By:

FENG LIN;
DETING XUE;
TAO XIE;
ZHIJUN PAN

Publication type:

Article

Small GTPase Rap1 Is Essential for Mouse Development and Formation of Functional Vasculature.

Published in:

PLoS ONE, 2015, v. 10, n. 12, p. 1, doi. 10.1371/journal.pone.0145689

By:

Chrzanowska-Wodnicka, Magdalena;
IIWhite, Gilbert C.;
Quilliam, Lawrence A.;
Whitehead, Kevin J.

Publication type:

Article

The Rac1 Inhibitor NSC23766 Exerts Anti-Influenza Virus Properties by Affecting the Viral Polymerase Complex Activity.

Published in:

PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0088520

By:

Dierkes, Rüdiger;
Warnking, Kathrin;
Liedmann, Swantje;
Seyer, Roman;
Ludwig, Stephan;
Ehrhardt, Christina

Publication type:

Article

Activation of Rac-1 and RhoA Contributes to Podocyte Injury in Chronic Kidney Disease.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0080328

By:

Babelova, Andrea;
Jansen, Felix;
Sander, Kerstin;
Löhn, Matthias;
Schäfer, Liliana;
Fork, Christian;
Ruetten, Hartmut;
Plettenburg, Oliver;
Stark, Holger;
Daniel, Christoph;
Amann, Kerstin;
Pavenstädt, Hermann;
Jung, Oliver;
Brandes, Ralf P.

Publication type:

Article

FERM Domain Containing Protein 7 Interacts with the Rho GDP Dissociation Inhibitor and Specifically Activates Rac1 Signaling.

Published in:

PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0073108

By:

Pu, Jiali;
Mao, Yanfang;
Lei, Xiaoguang;
Yan, Yaping;
Lu, Xiaoxiong;
Tian, Jun;
Yin, Xinzhen;
Zhao, Guohua;
Zhang, Baorong

Publication type:

Article

β-Arrestin2 Regulates Lysophosphatidic Acid-Induced Human Breast Tumor Cell Migration and Invasion <i>via</i> Rap1 and IQGAP1.

Published in:

PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0056174

By:

Alemayehu, Mistre;
Dragan, Magdalena;
Pape, Cynthia;
Siddiqui, Iram;
Sacks, David B.;
Di Guglielmo, Gianni M.;
Babwah, Andy V.;
Bhattacharya, Moshmi

Publication type:

Article

Knockdown of Ras-Related Protein 25 (Rab25) Inhibits the In Vitro Cytotoxicity and In Vivo Antitumor Activity of Human Glioblastoma Multiforme Cells.

Published in:

Oncology Research, 2017, v. 25, n. 3, p. 331, doi. 10.3727/096504016X14736286083065

By:

Bingqian Ding;
Bei Cui;
Ming Gao;
Zhenjiang Li;
Chenyang Xu;
Shaokang Fan;
Weiya He

Publication type:

Article

Binding of Multiple Rap1 Proteins Stimulates Chromosome Breakage Induction during DNA Replication.

Published in:

PLoS Genetics, 2015, v. 11, n. 8, p. 1, doi. 10.1371/journal.pgen.1005283

By:

Goto, Greicy H.;
Zencir, Sevil;
Hirano, Yukinori;
Ogi, Hiroo;
Ivessa, Andreas;
Sugimoto, Katsunori

Publication type:

Article

GORAB Missense Mutations Disrupt RAB6 and ARF5 Binding and Golgi Targeting.

Published in:

Journal of Investigative Dermatology, 2015, v. 135, n. 10, p. 2368, doi. 10.1038/jid.2015.192

By:

Egerer, Johannes;
Emmerich, Denise;
Fischer-Zirnsak, Björn;
Chan, Wing Lee;
Meierhofer, David;
Tuysuz, Beyhan;
Marschner, Katrin;
Sauer, Sascha;
Barr, Francis A;
Mundlos, Stefan;
Kornak, Uwe

Publication type:

Article

Stem cells: Holding tight onto the niche.

Published in:

Nature Reviews Molecular Cell Biology, 2012, v. 13, n. 5, p. 278, doi. 10.1038/nrm3342

By:

Baumann, Kim

Publication type:

Article

Proteomic analysis reveals KRIT1 as a modulator for the antioxidant effects of valproic acid in human bone-marrow mesenchymal stromal cells.

Published in:

Drug & Chemical Toxicology, 2015, v. 38, n. 3, p. 286, doi. 10.3109/01480545.2014.951762

By:

Jung, Kyoung Hwa;
Han, Dal Mu Ri;
Jeong, Sin-Gu;
Choi, Mi Ran;
Chai, Young Gyu;
Cho, Goang-Won

Publication type:

Article

cAMP controls the restoration of endothelial barrier function after thrombin-induced hyperpermeability via Rac1 activation.

Published in:

Physiological Reports, 2014, v. 2, n. 10, p. n/a, doi. 10.14814/phy2.12175

By:

Aslam, Muhammad;
Tanislav, Christian;
Troidl, Christian;
Schulz, Rainer;
Hamm, Christian;
Gündüz, Dursun

Publication type:

Article

Mutations in CDK5 RAP2 cause Seckel syndrome.

Published in:

Molecular Genetics & Genomic Medicine, 2015, v. 3, n. 5, p. 467, doi. 10.1002/mgg3.158

By:

Yigit, Gökhan;
Brown, Karen E.;
Kayserili, Hülya;
Pohl, Esther;
Caliebe, Almuth;
Zahnleiter, Diana;
Rosser, Elisabeth;
Bögershausen, Nina;
Uyguner, Zehra Oya;
Altunoglu, Umut;
Nürnberg, Gudrun;
Nürnberg, Peter;
Rauch, Anita;
Li, Yun;
Thiel, Christian Thomas;
Wollnik, Bernd

Publication type:

Article

Crucial role of the Rap G protein signal in Notch activation and leukemogenicity of T-cell acute lymphoblastic leukemia.

Published in:

Scientific Reports, 2015, p. 7978, doi. 10.1038/srep07978

By:

Doi, Keiko;
Imai, Takahiko;
Kressler, Christopher;
Yagita, Hideo;
Agata, Yasutoshi;
Vooijs, Marc;
Hamazaki, Yoko;
Inoue, Joe;
Minato, Nagahiro

Publication type:

Article