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Are the estrogen receptor and SIRT3 axes of the mitochondrial UPR key regulators of breast cancer subtype determination according to age?
- Published in:
- Aging & Cancer, 2021, v. 2, n. 3, p. 75, doi. 10.1002/aac2.12035
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- Article
Alternative mammary oncogenic pathways are induced by D-type cyclins; MMTV-cyclin D3 transgenic mice develop squamous cell carcinoma.
- Published in:
- Oncogene, 2003, v. 22, n. 28, p. 4425, doi. 10.1038/sj.onc.1206488
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- Article
A splice variant of Skp2 is retained in the cytoplasm and fails to direct cyclin D1 ubiquitination in the uterine cancer cell line SK-UT.
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- Oncogene, 2001, v. 20, n. 28, p. 3641, doi. 10.1038/sj.onc.1204501
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- Article
Inhibitory effect of p21 in MCF-7 cells is overcome by its coordinated stabilization with D-type cyclins.
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- Oncogene, 1999, v. 18, n. 47, p. 6454, doi. 10.1038/sj.onc.1203030
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- Article
Raloxifene is a Female-specific Proteostasis Therapeutic in the Spinal Cord.
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- Endocrinology, 2021, v. 162, n. 2, p. 1, doi. 10.1210/endocr/bqaa221
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- Article
Proteasome mapping reveals sexual dimorphism in tissue‐specific sensitivity to protein aggregations.
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- EMBO Reports, 2020, v. 21, n. 4, p. 1, doi. 10.15252/embr.201948978
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- Article
Skp2B attenuates p53 function by inhibiting prohibitin.
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- EMBO Reports, 2010, v. 11, n. 3, p. 220, doi. 10.1038/embor.2010.2
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- Article
Age alters the oncogenic trajectory toward luminal mammary tumors that activate unfolded proteins responses.
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- Aging Cell, 2022, v. 21, n. 10, p. 1, doi. 10.1111/acel.13665
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- Article
Toca-1 is suppressed by p53 to limit breast cancer cell invasion and tumor metastasis.
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- Breast Cancer Research, 2014, v. 16, n. 6, p. 59, doi. 10.1186/s13058-014-0503-x
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- Article
Toca-1 is suppressed by p53 to limit breast cancer cell invasion and tumor metastasis.
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- 2014
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- Publication type:
- journal article
Skp2 and Skp2B team up against Rb and p53.
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- Cell Division, 2011, v. 6, n. 1, p. 1, doi. 10.1186/1747-1028-6-1
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- Article
Doxycycline promotes proteasome fitness in the central nervous system.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-96540-z
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- Article
Ubiquitin-dependent and -independent mitochondrial protein quality controls: implications in ageing and neurodegenerative diseases.
- Published in:
- Molecular Microbiology, 2008, v. 70, n. 6, p. 1334, doi. 10.1111/j.1365-2958.2008.06502.x
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- Publication type:
- Article
Cyclin D1 and D3 associate with the SCF complex and are coordinately elevated in breast cancer.
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- Oncogene, 1999, v. 18, n. 11, p. 1983, doi. 10.1038/sj.onc.1202511
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- Publication type:
- Article
Cyclin D1 and D3 associate with the SCF complex and are coordinately elevated in breast cancer.
- Published in:
- Oncogene, 1999, v. 18, n. 11, p. 1983, doi. 10.1038/sj.onc.1202511
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- Publication type:
- Article
Skp2B Overexpression Alters a Prohibitin-p53 Axis and the Transcription of PAPP-A, the Protease of Insulin-Like Growth Factor Binding Protein 4.
- Published in:
- PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0022456
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- Article
Toward the identification and the targeting of key players of the mitochondrial unfolded protein response (UPR) in cancer.
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- Journal of Bioenergetics & Biomembranes, 2017, v. 49, n. 4, p. 291, doi. 10.1007/s10863-017-9716-x
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- Article
From discovery of the CHOP axis and targeting ClpP to the identification of additional axes of the UPRmt driven by the estrogen receptor and SIRT3.
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- Journal of Bioenergetics & Biomembranes, 2017, v. 49, n. 4, p. 297, doi. 10.1007/s10863-017-9722-z
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- Publication type:
- Article
The Mitochondrial Unfolded Protein Response as a non-Oncogene Addiction to Support Adaptation to Stress during Transformation in Cancer and Beyond.
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- Frontiers in Oncology, 2017, p. 1, doi. 10.3389/fonc.2017.00159
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- Publication type:
- Article
The Multi-Faced Role of PAPP-A in Post-Partum Breast Cancer: IGF-Signaling is Only the Beginning.
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- Journal of Mammary Gland Biology & Neoplasia, 2020, v. 25, n. 3, p. 181, doi. 10.1007/s10911-020-09456-1
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- Article
Cydlin D1 Overexpression and Response to Bortezomib Treatment in a Breast Cancer Model.
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- JNCI: Journal of the National Cancer Institute, 2006, v. 98, n. 17, p. 1238, doi. 10.1093/jnci/djj334
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- Article
Differential expression of the F-box proteins Skp2 and Skp2B in breast cancer.
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- Oncogene, 2005, v. 24, n. 21, p. 3448, doi. 10.1038/sj.onc.1208328
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- Publication type:
- Article
Sex specific activation of the ERα axis of the mitochondrial UPR (UPR<sup>mt</sup>) in the G93A-SOD1 mouse model of familial ALS.
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- Human Molecular Genetics, 2017, v. 26, n. 7, p. 1318, doi. 10.1093/hmg/ddx049
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- Article
KLF6-SV1 Drives Breast Cancer Metastasis and Is Associated with Poor Survival.
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- Science Translational Medicine, 2013, v. 5, n. 169, p. 1, doi. 10.1126/scitranslmed.3004688
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- Article
Can THEM6 targeting stop resistance to prostate cancer treatment?
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- EMBO Molecular Medicine, 2022, v. 14, n. 3, p. 1, doi. 10.15252/emmm.202115504
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- Article
Lactation opposes pappalysin-1-driven pregnancy-associated breast cancer.
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- EMBO Molecular Medicine, 2016, v. 8, n. 4, p. 388, doi. 10.15252/emmm.201606273
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- Article
Parity predisposes breasts to the oncogenic action of PAPP-A and activation of the collagen receptor DDR2.
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- 2019
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- Publication type:
- journal article
Germline CAG repeat length of the androgen receptor and time to progression in patients with prostate cancer treated with androgen deprivation therapy.
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- BJU International, 2011, v. 108, n. 7, p. 1086, doi. 10.1111/j.1464-410X.2010.10037.x
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- Article
Autophagy is a gatekeeper of hepatic differentiation and carcinogenesis by controlling the degradation of Yap.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07338-z
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- Article