Works matching DE "VIRAL nonstructural proteins"

Results: 505

Higher-order structures of the foot-and-mouth disease virus RNA-dependent RNA polymerase required for genome replication.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-021-02989-z

By:

Loundras, Eleni-Anna;
Streetley, James;
Herod, Morgan R.;
Thompson, Rebecca;
Harris, Mark;
Bhella, David;
Stonehouse, Nicola J.

Publication type:

Article

Nipah virus W protein harnesses nuclear 14-3-3 to inhibit NF-κB-induced proinflammatory response.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02797-5

By:

Enchéry, François;
Dumont, Claire;
Iampietro, Mathieu;
Pelissier, Rodolphe;
Aurine, Noémie;
Bloyet, Louis-Marie;
Carbonnelle, Caroline;
Mathieu, Cyrille;
Journo, Chloé;
Gerlier, Denis;
Horvat, Branka

Publication type:

Article

I(nsp1)ecting SARS-CoV-2–ribosome interactions.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02265-0

By:

Simeoni, Matthieu;
Cavinato, Théo;
Rodriguez, Daniel;
Gatfield, David

Publication type:

Article

Deep Drug Discovery of Mac Domain of SARS-CoV-2 (WT) Spike Inhibitors: Using Experimental ACE2 Inhibition TR-FRET Assay, Screening, Molecular Dynamic Simulations and Free Energy Calculations.

Published in:

Bioengineering (Basel), 2023, v. 10, n. 8, p. 961, doi. 10.3390/bioengineering10080961

By:

Iqbal, Saleem;
Lin, Sheng-Xiang

Publication type:

Article

The broad-spectrum antiviral recommendations for drug discovery against COVID-19.

Published in:

Drug Metabolism Reviews, 2020, v. 52, n. 3, p. 408, doi. 10.1080/03602532.2020.1770782

By:

Hazafa, Abu;
ur-Rahman, Khalil;
Haq, Ikram-ul-;
Jahan, Nazish;
Mumtaz, Muhammad;
Farman, Muhammad;
Naeem, Huma;
Abbas, Faheem;
Naeem, Muhammad;
Sadiqa, Sania;
Bano, Saira

Publication type:

Article

Glycyrrhizin Inhibits SARS-CoV-2 Entry into Cells by Targeting ACE2.

Published in:

Life (2075-1729), 2022, v. 12, n. 11, p. 1706, doi. 10.3390/life12111706

By:

He, Ming-Feng;
Liang, Jian-Hui;
Shen, Yan-Ni;
Zhang, Jin-Wen;
Liu, Ying;
Yang, Kuang-Yang;
Liu, Li-Chu;
Wang, Junyi;
Xie, Qian;
Hu, Chun;
Song, Xun;
Wang, Yan

Publication type:

Article

Comprehensive In Silico Screening of the Antiviral Potentialities of a New Humulene Glucoside from Asteriscus hierochunticus against SARS-CoV-2.

Published in:

Journal of Chemistry, 2021, p. 1, doi. 10.1155/2021/5541876

By:

Imieje, Vincent O.;
Zaki, Ahmed A.;
Metwaly, Ahmed M.;
Mostafa, Ahmad E.;
Elkaeed, Eslam B.;
Falodun, Abiodun

Publication type:

Article

Duck plague virus US3 protein kinase phosphorylates UL47 and regulates the subcellular localization of UL47.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 01, doi. 10.3389/fmicb.2022.876820

By:

Liyao Deng;
Jieyu Wan;
Anchun Cheng;
Mingshu Wang;
Bin Tian;
Ying Wu;
Qiao Yang;
Xumin Ou;
Sai Mao;
Di Sun;
Shaqiu Zhang;
Dekang Zhu;
Renyong Jia;
Shun Chen;
Mafeng Liu;
Xinxin Zhao;
Juan Huang;
Qun Gao;
Yanling Yu;
Ling Zhang

Publication type:

Article

Hepatitis E genotype 3 genome: A comprehensive analysis of entropy, motif conservation, relevant mutations, and clade-associated polymorphisms.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.1011662

By:

Muñoz-Chimeno, Milagros;
Rodriguez-Paredes, Vanessa;
Alejandra García-Lugo, Maira;
Avellon, Ana

Publication type:

Article

SARS-CoV-2 Nucleocapsid Protein Has DNA-Melting and Strand-Annealing Activities With Different Properties From SARS-CoV-2 Nsp13.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.851202

By:

Bo Zhang;
Yan Xie;
Zhaoling Lan;
Dayu Li;
Junjie Tian;
Qintao Zhang;
Hongji Tian;
Jiali Yang;
Xinnan Zhou;
Shuyi Qiu;
Keyu Lu;
Yang Liu

Publication type:

Article

Let's Get Physical: Flavivirus-Host Protein–Protein Interactions in Replication and Pathogenesis.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.847588

By:

Fishburn, Adam T.;
Pham, Oanh H.;
Kenaston, Matthew W.;
Beesabathuni, Nitin S.;
Shah, Priya S.

Publication type:

Article

Interferon-γ-Directed Inhibition of a Novel High-Pathogenic Phlebovirus and Viral Antagonism of the Antiviral Signaling by Targeting STAT1.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.01182

By:

Ning, Yun-Jia;
Mo, Qiong;
Feng, Kuan;
Min, Yuan-Qin;
Li, Mingyue;
Hou, Dianhai;
Peng, Cheng;
Zheng, Xin;
Deng, Fei;
Hu, Zhihong;
Wang, Hualin

Publication type:

Article

HSP90 is part of a protein complex with the L polymerase of Rift Valley fever phlebovirus and prevents its degradation by the proteasome during the viral genome replication/transcription stage.

Published in:

Frontiers in Cellular & Infection Microbiology, 2024, p. 01, doi. 10.3389/fcimb.2024.1331755

By:

Alem, Farhang;
Brahms, Ashwini;
Kaori Tarasaki;
Omole, Samson;
Kehn-Hall, Kylene;
Schmaljohn, Connie S.;
Bavari, Sina;
Makino, Shinji;
Hakami, Ramin M.

Publication type:

Article

Vaniprevir plus peginterferon alfa-2b and ribavirin in treatment-naive Japanese patients with hepatitis C virus genotype 1 infection: a randomized phase III study.

Published in:

2016

By:

Hayashi, Norio;
Nakamuta, Makoto;
Takehara, Tetsuo;
Kumada, Hiromitsu;
Takase, Akiko;
Howe, Anita;
Ludmerer, Steven;
Mobashery, Niloufar;
Howe, Anita Yee Mei;
Ludmerer, Steven W

Publication type:

journal article

The two faces of Rift Valley fever virus virulence factor NSs: The development of a vaccine and the elucidation of pathogenesis.

Published in:

2016

By:

Yamaoka, Satoko;
Ebihara, Hideki

Publication type:

Editorial

NS-1 antigen positive Dengue Infection and molecular characterization of Dengue Viruses in a private Medical College Hospitalin Dhaka, Bangladesh.

Published in:

Bangladesh Journal of Medical Science, 2018, v. 17, n. 4, p. 669, doi. 10.3329/bjms.v17i4.38334

By:

Siddiqua, M.;
Alam, A. N.;
Muraduzzaman, A. K. M.;
Tahmina, S.

Publication type:

Article

Predictive value of persistent NS1 antigen positivity beyond 3rd day for dengue haemorrhagic fever in Sri Lankan children.

Published in:

BMC Research Notes, 2019, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13104-019-4250-z

By:

Manamperi, Mihira;
Jayamanne, Bernard Deepal Wanniarachchi;
Somaratne, Thilini;
Perera, Natasha;
Fernando, LakKumar

Publication type:

Article

A localized surface plasmon resonance-amplified immunofluorescence biosensor for ultrasensitive and rapid detection of nonstructural protein 1 of Zika virus.

Published in:

PLoS ONE, 2019, v. 14, n. 1, p. 1, doi. 10.1371/journal.pone.0211517

By:

Takemura, Kenshin;
Adegoke, Oluwasesan;
Suzuki, Tetsuro;
Park, Enoch Y.

Publication type:

Article

Safety, tolerability, and pharmacokinetics of AL-335 in healthy volunteers and hepatitis C virus-infected subjects.

Published in:

PLoS ONE, 2018, v. 13, n. 10, p. 1, doi. 10.1371/journal.pone.0204974

By:

McClure, Matthew W.;
Berliba, Elina;
Tsertsvadze, Tengiz;
Streinu-Cercel, Adrian;
Vijgen, Leen;
Astruc, Béatrice;
Patat, Alain;
Westland, Christopher;
Chanda, Sushmita;
Zhang, Qingling;
Kakuda, Thomas N.;
Vuong, Jennifer;
Khorlin, Nick;
Beigelman, Leonid;
Blatt, Lawrence M.;
Fry, John

Publication type:

Article

Comparison of two rapid diagnostic tests during a large dengue virus serotype 3 outbreak in the Solomon Islands in 2013.

Published in:

PLoS ONE, 2018, v. 13, n. 8, p. 1, doi. 10.1371/journal.pone.0202304

By:

Liu, Li-Teh;
Wang, Ying-Hui;
Lin, Ping-Chang;
Tsai, Ching-Yi;
Tsai, Jih-Jin;
Dalipanda, Tenneth;
Jagilly, Rooney;
Lai, Wen-Ter

Publication type:

Article

The association between obesity and dengue virus (DENV) infection in hospitalised patients.

Published in:

PLoS ONE, 2018, v. 13, n. 7, p. 1, doi. 10.1371/journal.pone.0200698

By:

Tan, Victoria Phooi Khei;
Ngim, Chin Fang;
Lee, Erika Ziyan;
Ramadas, Amutha;
Pong, Lian Yih;
Ng, Joo Ing;
Hassan, Sharifah Syed;
Ng, Xuan Ye;
Dhanoa, Amreeta

Publication type:

Article

Clinically approved chemical-controlled suppression of protein expression in BmN cells.

Published in:

Journal of Insect Biotechnology & Sericology, 2024, v. 93, n. 1, p. 1

By:

Toshiki Nakanishi;
Shin-ichiro Asano;
Hisanori Bando;
Masanao Sato

Publication type:

Article

Structure, function and immune evasion strategies of aquareoviruses, with focus on grass carp reovirus.

Published in:

Reviews in Aquaculture, 2024, v. 16, n. 1, p. 410, doi. 10.1111/raq.12844

By:

Li, Peng Wei;
Zhang, Jie;
Chang, Ming Xian

Publication type:

Article

In vitro antiviral activity of Lactobacillus casei and Bifidobacterium adolescentis against rotavirus infection monitored by NSP4 protein production.

Published in:

Journal of Applied Microbiology, 2016, v. 120, n. 4, p. 1041, doi. 10.1111/jam.13069

By:

Olaya Galán, N.N.;
Ulloa Rubiano, J.C.;
Velez Reyes, F.A.;
Fernandez Duarte, K.P.;
Salas Cárdenas, S.P.;
Gutierrez Fernandez, M.F.

Publication type:

Article

Geological Structure and Petroleum Potential of the Kara Sea Shelf.

Published in:

Doklady Earth Sciences, 2019, v. 489, n. 1, p. 1289, doi. 10.1134/S1028334X19110229

By:

Kontorovich, V. A.;
Kontorovich, A. E.

Publication type:

Article

PPP2R5D promotes hepatitis C virus infection by binding to viral NS5B and enhancing viral RNA replication.

Published in:

Virology Journal, 2022, v. 19, n. 1, p. 1, doi. 10.1186/s12985-022-01848-5

By:

Anwar, Muhammad Ikram;
Li, Ni;
Zhou, Qing;
Chen, Mingxiao;
Hu, Chengguang;
Wu, Tao;
Chen, Haihang;
Li, Yi-Ping;
Zhou, Yuanping

Publication type:

Article

Tertiary Structures of Haseki Tick Virus Nonstructural Proteins Are Similar to Those of Orthoflaviviruses.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 24, p. 13654, doi. 10.3390/ijms252413654

By:

Gladysheva, Anastasia;
Osinkina, Irina;
Radchenko, Nikita;
Alkhireenko, Daria;
Agafonov, Alexander

Publication type:

Article

GETV nsP2 plays a critical role in the interferon antagonism and viral pathogenesis.

Published in:

Cell Communication & Signaling, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12964-023-01392-x

By:

Mou, Chunxiao;
Meng, Hui;
Shi, Kaichuang;
Huang, Yanmei;
Liu, Meiqi;
Chen, Zhenhai

Publication type:

Article

Human Enterovirus Nonstructural Protein 2C<sup>ATPase</sup> Functions as Both an RNA Helicase and ATP-Independent RNA Chaperone.

Published in:

PLoS Pathogens, 2015, v. 11, n. 7, p. 1, doi. 10.1371/journal.ppat.1005067

By:

Xia, Hongjie;
Wang, Peipei;
Wang, Guang-Chuan;
Yang, Jie;
Sun, Xianlin;
Wu, Wenzhe;
Qiu, Yang;
Shu, Ting;
Zhao, Xiaolu;
Yin, Lei;
Qin, Cheng-Feng;
Hu, Yuanyang;
Zhou, Xi

Publication type:

Article

Hepatitis C Virus RNA Replication Depends on Specific Cis- and Trans-Acting Activities of Viral Nonstructural Proteins.

Published in:

PLoS Pathogens, 2015, v. 11, n. 4, p. 1, doi. 10.1371/journal.ppat.1004817

By:

Kazakov, Teymur;
Yang, Feng;
Ramanathan, Harish N.;
Lindenbach, Brett D.;
Kohlway, Andrew;
Diamond, Michael S.

Publication type:

Article

A Crystal Structure of the Dengue Virus NS5 Protein Reveals a Novel Inter-domain Interface Essential for Protein Flexibility and Virus Replication.

Published in:

PLoS Pathogens, 2015, v. 11, n. 3, p. 1, doi. 10.1371/journal.ppat.1004682

By:

Zhao, Yongqian;
Soh, Tingjin Sherryl;
Zheng, Jie;
Chan, Kitti Wing Ki;
Phoo, Wint Wint;
Lee, Chin Chin;
Tay, Moon Y. F.;
Swaminathan, Kunchithapadam;
Cornvik, Tobias C.;
Lim, Siew Pheng;
Shi, Pei-Yong;
Lescar, Julien;
Vasudevan, Subhash G.;
Luo, Dahai

Publication type:

Article

Japanese Encephalitis Virus Nonstructural Protein NS5 Interacts with Mitochondrial Trifunctional Protein and Impairs Fatty Acid β-Oxidation.

Published in:

PLoS Pathogens, 2015, v. 11, n. 3, p. 1, doi. 10.1371/journal.ppat.1004750

By:

Kao, Yu-Ting;
Chang, Bi-Lan;
Liang, Jian-Jong;
Tsai, Hang-Jen;
Lee, Yi-Ling;
Lin, Ren-Jye;
Lin, Yi-Ling

Publication type:

Article

Aminoterminal Amphipathic α-Helix AH1 of Hepatitis C Virus Nonstructural Protein 4B Possesses a Dual Role in RNA Replication and Virus Production.

Published in:

PLoS Pathogens, 2014, v. 10, n. 11, p. 1, doi. 10.1371/journal.ppat.1004501

By:

Gouttenoire, Jérôme;
Montserret, Roland;
Paul, David;
Castillo, Rosa;
Meister, Simon;
Bartenschlager, Ralf;
Penin, François;
Moradpour, Darius

Publication type:

Article

A Quantitative High-Resolution Genetic Profile Rapidly Identifies Sequence Determinants of Hepatitis C Viral Fitness and Drug Sensitivity.

Published in:

PLoS Pathogens, 2014, v. 10, n. 4, p. 1, doi. 10.1371/journal.ppat.1004064

By:

Qi, Hangfei;
Olson, C. Anders;
Wu, Nicholas C.;
Ke, Ruian;
Loverdo, Claude;
Chu, Virginia;
Truong, Shawna;
Remenyi, Roland;
Chen, Zugen;
Du, Yushen;
Su, Sheng-Yao;
Al-Mawsawi, Laith Q.;
Wu, Ting-Ting;
Chen, Shu-Hua;
Lin, Chung-Yen;
Zhong, Weidong;
Lloyd-Smith, James O.;
Sun, Ren

Publication type:

Article

Rational design of highly potent broad-spectrum enterovirus inhibitors targeting the nonstructural protein 2C.

Published in:

PLoS Biology, 2020, v. 18, n. 11, p. 1, doi. 10.1371/journal.pbio.3000904

By:

Bauer, Lisa;
Manganaro, Roberto;
Zonsics, Birgit;
Hurdiss, Daniel L.;
Zwaagstra, Marleen;
Donselaar, Tim;
Welter, Naemi G. E.;
van Kleef, Regina G. D. M.;
Lopez, Moira Lorenzo;
Bevilacqua, Federica;
Raman, Thamidur;
Ferla, Salvatore;
Bassetto, Marcella;
Neyts, Johan;
Strating, Jeroen R. P. M.;
Westerink, Remco H. S.;
Brancale, Andrea;
van Kuppeveld, Frank J. M.

Publication type:

Article

Affinity selection‐mass spectrometry in the discovery of anti‐SARS‐CoV‐2 compounds.

Published in:

Mass Spectrometry Reviews, 2024, v. 43, n. 1, p. 39, doi. 10.1002/mas.21800

By:

van Breemen, Richard B.;
Muchiri, Ruth N.

Publication type:

Article

First molecular detection of porcine bocavirus in Malaysia.

Published in:

Tropical Animal Health & Production, 2018, v. 50, n. 4, p. 733, doi. 10.1007/s11250-017-1489-z

By:

Mohan Jacob, Daniel;
Lee, Chee Yien;
Arshad, Siti Suri;
Selvarajah, Gayathri Thevi;
Bande, Faruku;
Ong, Bee Lee;
Ooi, Peck Toung

Publication type:

Article

What the VAP: The Expanded VAP Family of Proteins Interacting With FFAT and FFAT-Related Motifs for Interorganellar Contact.

Published in:

Contact (25152564), 2021, v. 4, p. 1, doi. 10.1177/25152564211012246

By:

Neefjes, Jacques;
Cabukusta, Birol

Publication type:

Article

Angriff auf den Respirationstrakt.

Published in:

Trillium-Diagnostik, 2019, v. 17, n. 1, p. 13

By:

Becker, Jürgen

Publication type:

Article

The current state of validated small molecules inhibiting SARS-CoV-2 nonstructural proteins.

Published in:

Turkish Journal of Biology, 2021, v. 45, p. 469, doi. 10.3906/biy-2106-42

By:

KOCABAŞ, Fatih;
USLU, Merve

Publication type:

Article

Identification of the critical linker residues conferring differences in the compactness of NS5 from Dengue virus serotype 4 and NS5 from Dengue virus serotypes 1-3.

Published in:

Acta Crystallographica: Section D, Structural Biology, 2016, v. 72, n. 6, p. 795, doi. 10.1107/S2059798316006665

By:

Subramanian Manimekalai, Malathy Sony;
Saw, Wuan Geok;
Pan, Ankita;
Grüber, Ardina;
Grüber, Gerhard

Publication type:

Article

Divergent effects of warming on nonstructural carbohydrates in woody plants: a meta‐analysis.

Published in:

Physiologia Plantarum, 2023, v. 175, n. 6, p. 1, doi. 10.1111/ppl.14117

By:

He, Rui;
Shi, Hang;
Hu, Man;
Zhou, Quan;
Zhang, Quanfa;
Dang, Haishan

Publication type:

Article

The impact of the suppression of highly connected protein interactions on the corona virus infection.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-13373-0

By:

Torres, Felipe;
Kiwi, Miguel;
Schuller, Ivan K.

Publication type:

Article

Epidemiological associations with genomic variation in SARS-CoV-2.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-02548-w

By:

Rahnavard, Ali;
Dawson, Tyson;
Clement, Rebecca;
Stearrett, Nathaniel;
Pérez-Losada, Marcos;
Crandall, Keith A.

Publication type:

Article

Flavivirus Nonstructural Protein NS5 Dysregulates HSP90 to Broadly Inhibit JAK/STAT Signaling.

Published in:

Cells (2073-4409), 2020, v. 9, n. 4, p. 899, doi. 10.3390/cells9040899

By:

Roby, Justin A.;
Esser-Nobis, Katharina;
Dewey-Verstelle, Elyse C.;
Fairgrieve, Marian R.;
Schwerk, Johannes;
Lu, Amy Y.;
Soveg, Frank W.;
Hemann, Emily A.;
Hatfield, Lauren D.;
Keller, Brian C.;
Shapiro, Alexander;
Forero, Adriana;
Stencel-Baerenwald, Jennifer E.;
Savan, Ram;
Gale, Michael

Publication type:

Article

Network of Interactions between ZIKA Virus Non-Structural Proteins and Human Host Proteins.

Published in:

Cells (2073-4409), 2020, v. 9, n. 1, p. 1, doi. 10.3390/cells9010153

By:

Golubeva, Volha A.;
Nepomuceno, Thales C.;
de Gregoriis, Giuliana;
Mesquita, Rafael D.;
Xueli Li;
Dash, Sweta;
Garcez, Patrícia P.;
Suarez-Kurtz, Guilherme;
Izumi, Victoria;
Koomen, John;
Carvalho, Marcelo A.;
Monteiro, Alvaro N. A.

Publication type:

Article

Effectiveness of a fixed combination formula of ombitasvir/paritaprevir/ritonavir for hepatitis C virus infection in patients on maintenance haemodialysis.

Published in:

Nephrology, 2017, v. 22, n. 7, p. 562, doi. 10.1111/nep.13011

By:

Morisawa, Norihiko;
Koshima, Yohei;
Kuriyama, Satoru;
Matsuyama, Momoko;
Hayashi, Naomi;
Satoh, Jun‐ichi;
Amemiya, Morimasa;
Yokoo, Takashi

Publication type:

Article

High efficacy of sofosbuvir/velpatasvir and impact of baseline resistance‐associated substitutions in hepatitis C genotype 3 infection.

Published in:

Alimentary Pharmacology & Therapeutics, 2018, v. 47, n. 9, p. 1288, doi. 10.1111/apt.14592

By:

von Felden, J.;
Vermehren, J.;
Ingiliz, P.;
Mauss, S.;
Lutz, T.;
Simon, K. G.;
Busch, H. W.;
Baumgarten, A.;
Schewe, K.;
Hueppe, D.;
Boesecke, C.;
Rockstroh, J. K.;
Daeumer, M.;
Luebke, N.;
Timm, J.;
Schulze zur Wiesch, J.;
Sarrazin, C.;
Christensen, S.

Publication type:

Article

The cost-effectiveness of testing for NS5a resistance-associated polymorphisms at baseline in genotype 1a-infected (treatment-naïve and treatment-experienced) subjects treated with all-oral elbasvir/grazoprevir regimens in the United States.

Published in:

Alimentary Pharmacology & Therapeutics, 2017, v. 45, n. 3, p. 455, doi. 10.1111/apt.13882

By:

Elbasha, E. H.;
Robertson, M. N.;
Nwankwo, C.

Publication type:

Article

Structures of SARS-CoV-2 RNA-Binding Proteins and Therapeutic Targets.

Published in:

Intervirology, 2021, v. 64, n. 2, p. 55, doi. 10.1159/000513686

By:

Khan, Muhammad Tahir;
Irfan, Muhammad;
Ahsan, Hina;
Ahmed, Abrar;
Kaushik, Aman Chandra;
Khan, Anwar Sheed;
Chinnasamy, Sathishkumar;
Ali, Arif;
Wei, Dong-Qing

Publication type:

Article