Works matching Chagas' disease

Results: 5000

Deep Sequencing to Detect Diversity of Trypanosoma cruzi Infection in Patients Coinfected With Human Immunodeficiency Virus and Chagas Disease.

Published in:

2022

By:

Bowman, Natalie M;
Balasubramanian, Sujata;
Gilman, Robert H;
Parobek, Christian;
Calderon, Maritza;
Waltmann, Andreea;
Messenger, Louisa A;
Sanchez, Leny;
Bern, Caryn;
Juliano, Jonathan J;
Peru, Working Group on Chagas Disease in Bolivia and;
Working Group on Chagas Disease in Bolivia and Peru

Publication type:

journal article

SINTOMATOLOGIA DA DOENÇA DE CHAGAS EM PACIENTES IDOSOS.

Published in:

Revista Foco (Interdisciplinary Studies Journal), 2023, v. 16, n. 8, p. 1, doi. 10.54751/revistafoco.v16n8-063

By:

Tanure Jardim, Paula Fulgêncio;
Gomes Fialho, Flávia;
Lopes Silva, Ana Luísa;
Sousa, Luana;
Galantini Silveira, Isabela;
Assis Martins, Rangel Antonio;
Faria Martins, Laura;
Costa de Oliveira, Letícia;
Martins Fernandes, Mariana;
de Oliveira Grillo, Marcela

Publication type:

Article

Nursing Student's Knowledge Assessment about Chagas Disease.

Published in:

Salud Uninorte, 2018, v. 34, n. 3, p. 565

By:

Montaño Bohórquez, Yuli;
Galvis Pabón, Jairo;
García Rueda, Alexandra;
Mendoza Becerra, Jessica;
Roa Díaz, Zayne;
Camargo Ramírez, Martha

Publication type:

Article

Tolerance to nifurtimox and benznidazole in adult patients with chronic Chagas' disease.

Published in:

2020

By:

Jackson, Yves;
Wyssa, Baptiste;
Chappuis, François

Publication type:

journal article

Modeling the effects of palm-house proximity on the theoretical risk of Chagas disease transmission in a rural locality of the Orinoco basin, Colombia.

Published in:

Parasites & Vectors, 2016, v. 9, p. 1, doi. 10.1186/s13071-016-1884-8

By:

Erazo, Diana;
Cordovez, Juan

Publication type:

Article

Tratamiento posparto en una paciente con enfermedad de Chagas, sin interrupción de la lactancia.

Published in:

2015

By:

Vela-Bahena, Luz Elena;
Vergara, Raymundo;
Vite, Ludmila;
Ramos, Celso

Publication type:

Case Study

Avaliação do conhecimento sobre a doença de Chagas em escolares das zonas rural e urbana de municípios endêmicos em Minas Gerais.

Published in:

Physis: Revista de Saúde Coletiva, 2022, v. 32, n. 3, p. 1, doi. 10.1590/S0103-73312022320319

By:

Prado Vivas, Anita Luiza;
Aparecida Ferreira, Raquel;
Ribeiro de Oliveira, Eduardo;
Marques Ianes, Iara;
Ermelinda Barbosa, Silvia

Publication type:

Article

Evaluation of Cytokine Profile and HLA Association in Benznidazole Related Cutaneous Reactions in Patients With Chagas Disease.

Published in:

Clinical Infectious Diseases, 2015, v. 61, n. 11, p. 1688, doi. 10.1093/cid/civ690

By:

Salvador, Fernando;
Sánchez-Montalvá, Adrián;
Martínez-Gallo, Mónica;
Sala-Cunill, Anna;
Viñas, Laura;
García-Prat, Marina;
Aparicio, Gloria;
Avilés, Augusto Sao;
Artaza, Ma Ángeles;
Ferrer, Berta;
Molina, Israel

Publication type:

Article

Chagas’ disease: an update on immune mechanisms and therapeutic strategies.

Published in:

Journal of Cellular & Molecular Medicine, 2010, v. 14, n. 6b, p. 1373, doi. 10.1111/j.1582-4934.2010.01007.x

By:

Boscardin, Silvia Beatriz;
Torrecilhas, Ana Claudia Troccoli;
Manarin, Romina;
Revelli, Silvia;
Rey, Elena Gonzalez;
Tonelli, Renata Rosito;
Silber, Ariel Mariano

Publication type:

Article

Editorial: Recent advances in the prevention, diagnosis and treatment of Chagas disease.

Published in:

Frontiers in Microbiology, 2025, p. 1, doi. 10.3389/fmicb.2024.1537105

By:

Frechiani, Giovanna;
Vieyra, Adalberto;
Dick, Claudia F.

Publication type:

Article

ADENOSINE DEAMINASE ACTIVITY AND SERUM C-REACTIVE PROTEIN AS PROGNOSTIC MARKERS OF CHAGAS DISEASE SEVERITY.

Published in:

Revista do Instituto de Medicina Tropical de São Paulo, 2015, v. 57, n. 5, p. 385, doi. 10.1590/S0036-46652015000500003

By:

BRAVO-TOBAR, Iván Darío;
NELLO-PÉREZ, Carlota;
FERNÁNDEZ, Alí;
MOGOLLÓN, Nora;
PÉREZ, Mary Carmen;
VERDE, Juan;
CONCEPCIÓN, Juan Luis;
RODRIGUEZ-BONFANTE, Claudina;
BONFANTE-CABARCAS, Rafael

Publication type:

Article

CLINICAL AND EPIDEMIOLOGICAL PROFILE OF ELDERLY PATIENTS WITH CHAGAS DISEASE FOLLOWED BETWEEN 2005-2013 BY PHARMACEUTICAL CARE SERVICE IN CEARÁ STATE, NORTHEASTERN BRAZIL.

Published in:

Revista do Instituto de Medicina Tropical de São Paulo, 2015, v. 57, n. 2, p. 145, doi. 10.1590/S0036-46652015000200008

By:

dos Santos PEREIRA, Laíse;
FREITAS, Erlane Chaves;
de Barros Vasconcelos FIDALGO, Arduína Sofia Ortet;
ANDRADE, Mônica Coelho;
da Silva CÂNDIDO, Darlan;
SILVA FILHO, José Dãmiao da;
MICHAILOWSKY, Vladimir;
de Fátima OLIVEIRA, Maria;
QUEIROZ, José Ajax Nogueira

Publication type:

Article

Chagas’ disease: lessons from routine donation testing.

Published in:

Transfusion Medicine, 2009, v. 19, n. 1, p. 16, doi. 10.1111/j.1365-3148.2009.00915.x

By:

Castro, E.

Publication type:

Article

Control de la infección por Trypanosoma cruzi/Enfermedad de Chagas en gestantes Latinoamericanas y sus hijos.

Published in:

Revista Española de Quimioterapia, 2013, v. 26, n. 3, p. 253

By:

Merino, Francisco J.;
Martínez-Ruiz, Rocío;
Olabarrieta, Iciar;
Merino, Paloma;
García-Bujalance, Silvia;
Gastañaga, Teresa;
Flores-Chavez, María

Publication type:

Article

A DOENÇA DE CHAGAS: REPERCUSSÕES DE UMA DESCOBERTA CIENTÍFICA BRASILEIRA EM PORTUGAL, 1909-1924.

Published in:

Ler Historia, 2022, n. 80, p. 159

By:

Figueiredo Moura da Silva, Ewerton Luiz

Publication type:

Article

Synthesis of Galα(1,3)Galβ(1,4)GlcNAcα-, Galβ (1,4)GlcNAcα- and GlcNAc-containing neoglycoproteins and their immunological evaluation in the context of Chagas disease.

Published in:

Glycobiology, 2016, v. 26, n. 1, p. 39, doi. 10.1093/glycob/cwv081

By:

Schocker, Nathaniel S.;
Portillo, Susana;
Brito, Carlos R. N.;
Marques, Alexandre F.;
Almeida, Igor C.;
Michael, Katja

Publication type:

Article

Neurological Manifestations in Chagas Disease without Cardiac Dysfunction: Correlation between Dysfunction of the Parasympathetic Nervous System and White Matter Lesions in the Brain.

Published in:

Journal of Neuroimaging, 2009, v. 19, n. 4, p. 332, doi. 10.1111/j.1552-6569.2008.00305.x

By:

Py, Marco;
Pedrosa, Roberto;
Silveira, Juliana;
Medeiros, Aline;
Andre, Charles

Publication type:

Article

Opportunities for Improved Chagas Disease Vector Control Based on Knowledge, Attitudes and Practices of Communities in the Yucatan Peninsula, Mexico.

Published in:

PLoS Neglected Tropical Diseases, 2014, v. 8, n. 3, p. 1, doi. 10.1371/journal.pntd.0002763

By:

Rosecrans, Kathryn;
Cruz-Martin, Gabriela;
King, Ashley;
Dumonteil, Eric

Publication type:

Article

Diagnosis and Treatment of Congenital Chagas Disease in a Premature Infant.

Published in:

2016

By:

Alarcón, Andrés;
Morgan, Mackenzie;
Montgomery, Susan P.;
Scavo, Louis;
Wong, Edward C. C.;
Hahn, Andrea;
Jantausch, Barbara

Publication type:

Case Study

Comparative population dynamics of the bug Mepraia spinolai, a sylvatic vector of Chagas’ disease, in different hosts.

Published in:

Medical & Veterinary Entomology, 2009, v. 23, n. 2, p. 106, doi. 10.1111/j.1365-2915.2009.00795.x

By:

ACUÑA-RETAMAR, M.;
BOTTO-MAHAN, C.;
CANALS, M.;
CORREA, J. P.;
CATTAN, P. E.

Publication type:

Article

Increased mortality attributed to Chagas disease: a systematic review and meta-analysis.

Published in:

Parasites & Vectors, 2016, v. 9, p. 1, doi. 10.1186/s13071-016-1315-x

By:

Cucunubá, Zulma M.;
Okuwoga, Omolade;
Basáñez, María-Gloria;
Nouvellet, Pierre

Publication type:

Article

Prophylactic and therapeutic DNA vaccines against Chagas disease.

Published in:

Parasites & Vectors, 2015, v. 8, n. 1, p. 1, doi. 10.1186/s13071-015-0738-0

By:

Arce-Fonseca, Minerva;
Rios-Castro, Martha;
del Carmen Carrillo-Sánchez, Silvia;
Martínez-Cruz, Mariana;
Rodríguez-Morales, Olivia

Publication type:

Article

Impact of benznidazole treatment on the functional response of Trypanosoma cruzi antigen-specific CD4+CD8+ T cells in chronic Chagas disease patients.

Published in:

PLoS Neglected Tropical Diseases, 2018, v. 12, n. 5, p. 1, doi. 10.1371/journal.pntd.0006480

By:

Pérez-Antón, Elena;
Egui, Adriana;
Thomas, M. Carmen;
Puerta, Concepción J.;
González, John Mario;
Cuéllar, Adriana;
Segovia, Manuel;
López, Manuel Carlos

Publication type:

Article

Are the London Declaration’s 2020 goals sufficient to control Chagas disease?: Modeling scenarios for the Yucatan Peninsula.

Published in:

PLoS Neglected Tropical Diseases, 2018, v. 12, n. 3, p. 1, doi. 10.1371/journal.pntd.0006337

By:

Lee, Bruce Y.;
Bartsch, Sarah M.;
Skrip, Laura;
Hertenstein, Daniel L.;
Avelis, Cameron M.;
Ndeffo-Mbah, Martial;
Tilchin, Carla;
Dumonteil, Eric O.;
Galvani, Alison

Publication type:

Article

Reactivación de la enfermedad de Chagas después de trasplante autólogo de progenitores hematopoyéticos. Reporte de caso y revisión de la literatura.

Published in:

Biomédica: Revista del Instituto Nacional de Salud, 2022, v. 42, n. 2, p. 224, doi. 10.7705/biomedica.6288

By:

David Rojas, Juan;
Pereira, Mario;
Martínez, Bibiana;
César Gómez, Julio;
Isabel Cuervo, Sonia

Publication type:

Article

Doença de Chagas: enfrentando a invisibilidade pela análise de histórias de vida de portadores crônicos.

Published in:

Revista Ciência & Saúde Coletiva, 2022, v. 27, n. 5, p. 1939, doi. 10.1590/1413-81232022275.08492021

By:

Sant'Ana Pereira-Silva, Fernanda;
Braga Corrêa de Mello, Marcio Luiz;
Cremonini de Araújo-Jorge, Tania

Publication type:

Article

Transplantation for Chagas’ disease: an overview of immunosuppression and reactivation in the last two decades.

Published in:

Clinical Transplantation, 2010, v. 24, n. 2, p. E29, doi. 10.1111/j.1399-0012.2009.01202.x

By:

Bacal, Fernando;
Silva, Christiano Pereira;
Pires, Philippe Vieira;
Mangini, Sandrigo;
Fiorelli, Alfredo Inacio;
Stolf, Noedir Groppo;
Bocchi, Edimar Alcides

Publication type:

Article

Development of a PCR Assay to Detect Low Level Trypanosoma cruzi in Blood Specimens Collected with PAXgene Blood DNA Tubes for Clinical Trials Treating Chagas Disease.

Published in:

PLoS Neglected Tropical Diseases, 2016, v. 10, n. 12, p. 1, doi. 10.1371/journal.pntd.0005146

By:

Wei, Bo;
Chen, Lei;
Kibukawa, Miho;
Kang, John;
Waskin, Hetty;
Marton, Matthew

Publication type:

Article

One Health Interactions of Chagas Disease Vectors, Canid Hosts, and Human Residents along the Texas-Mexico Border.

Published in:

PLoS Neglected Tropical Diseases, 2016, v. 10, n. 11, p. 1, doi. 10.1371/journal.pntd.0005074

By:

Garcia, Melissa N.;
O’Day, Sarah;
Fisher-Hoch, Susan;
Gorchakov, Rodion;
Patino, Ramiro;
Feria Arroyo, Teresa P.;
Laing, Susan T.;
Lopez, Job E.;
Ingber, Alexandra;
Jones, Kathryn M.;
Murray, Kristy O.

Publication type:

Article

Impact of Helminth Infection on the Clinical and Microbiological Presentation of Chagas Diseases in Chronically Infected Patients.

Published in:

PLoS Neglected Tropical Diseases, 2016, v. 10, n. 4, p. 1, doi. 10.1371/journal.pntd.0004663

By:

Salvador, Fernando;
Sulleiro, Elena;
Sánchez-Montalvá, Adrián;
Martínez-Gallo, Mónica;
Carrillo, Eugenia;
Molina, Israel

Publication type:

Article

Applicability of the PAINESD risk score for 30-day mortality prediction post ventricular tachycardia catheter ablation in Chagas disease.

Published in:

Journal of Interventional Cardiac Electrophysiology, 2021, v. 62, n. 3, p. 469, doi. 10.1007/s10840-021-00995-z

By:

Kulchetscki, R. M.;
Pisani, C. F.;
Alexandre, F. K. B.;
Mayrink, M. P.;
Ferraz, A. P.;
Gouvea, F. C.;
Goncalves, A. L. M.;
Hardy, C. A.;
Melo, S. L.;
Chokr, M. O.;
Scanavacca, M. I.

Publication type:

Article

Effects of repetitive stress during the acute phase of Trypanosoma cruzi infection on chronic Chagas' disease in rats.

Published in:

Stress: The International Journal on the Biology of Stress, 2009, v. 12, n. 2, p. 144, doi. 10.1080/10253890802168648

By:

Cristina Caetano, Leony;
Brazão, Vânia;
Del Vecchio Filipin, Marina;
Helena Santello, Fabricia;
Naiara Caetano, Luana;
Paula Alonso Toldo, Miriam;
Caldeira, Jerri C.;
Clóvis do Prado Júnior, José

Publication type:

Article

OS AVANÇOS DA BIOMEDICINA NO DIAGNÓSTICO DE PACIENTES ACOMETIDOS POR DOENÇA DE CHAGAS.

Published in:

Revista Foco (Interdisciplinary Studies Journal), 2024, v. 17, n. 11, p. 1, doi. 10.54751/revistafoco.v17n11-229

By:

Ribeiro Macedo, Abia Gomes;
de Sá Alves, Darah;
Lima de Alencar, Silvana

Publication type:

Article

Intranasal Trans-Sialidase Vaccine Mitigates Acute and Chronic Pathology in a Preclinical Oral Chagas Disease Model.

Published in:

Vaccines, 2024, v. 12, n. 10, p. 1171, doi. 10.3390/vaccines12101171

By:

Pacini, Maria Florencia;
Bulfoni Balbi, Camila;
Dinatale, Brenda;
Farré, Cecilia;
Cacik, Paula;
Gonzalez, Florencia Belén;
Marcipar, Iván;
Pérez, Ana Rosa

Publication type:

Article

Chagas Disease Diagnosis with Trypanosoma cruzi -Exclusive Epitopes in GFP.

Published in:

Vaccines, 2024, v. 12, n. 9, p. 1029, doi. 10.3390/vaccines12091029

By:

Durans, Andressa da M.;
Napoleão-Pêgo, Paloma;
Reis, Flavia C. G.;
Dias, Evandro R.;
Machado, Luciana E. S. F.;
Lechuga, Guilherme C.;
Junqueira, Angela C. V.;
De-Simone, Salvatore G.;
Provance Jr., David W.

Publication type:

Article

American trypanosomiasis (Chagas disease) in solid organ transplantation.

Published in:

Transplant Infectious Disease, 2020, v. 22, n. 6, p. 1, doi. 10.1111/tid.13429

By:

Radisic, Marcelo V.;
Repetto, Silvia A.

Publication type:

Article

Sequential measurement of Trypanosoma cruzi parasitic load in endomyocardial biopsies for early detection and follow‐up of Chagas disease reactivation after heart transplantation.

Published in:

Transplant Infectious Disease, 2020, v. 22, n. 1, p. 1, doi. 10.1111/tid.13209

By:

Benvenuti, Luiz Alberto;
Roggério, Alessandra;
Nishiya, Anna Shoko;
Mangini, Sandrigo;
Levi, José Eduardo

Publication type:

Article

Interleukin 10 Polymorphisms as Risk Factors for Progression to Chagas Disease Cardiomyopathy: A Case-Control Study and Meta-Analysis.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.946350

By:

Grijalva, Alicia;
Vaulet, Lucia Gallo;
Agüero, Roberto Nicolas;
Toledano, Analia;
Risso, Marikena Guadalupe;
Braghini, Juan Quarroz;
Sosa, David;
Ruybal, Paula;
Repetto, Silvia;
Alba Soto, Catalina Dirney

Publication type:

Article

Highly conserved CDR3 region in circulating CD4+Vβ5+ T cells may be associated with cytotoxic activity in Chagas disease.

Published in:

Clinical & Experimental Immunology, 2012, v. 169, n. 2, p. 109, doi. 10.1111/j.1365-2249.2012.04608.x

By:

Menezes, C. A. S.;
Sullivan, A. K.;
Falta, M. T.;
Mack, D. G.;
Freed, B. M.;
Rocha, M. O. C.;
Gollob, K. J.;
Fontenot, A. P.;
Dutra, W. O.

Publication type:

Article

Anti-galectin-1 autoantibodies in human Trypanosoma cruzi infection: differential expression of this β-galactoside-binding protein in cardiac Chagas' disease.

Published in:

Clinical & Experimental Immunology, 2001, v. 124, n. 2, p. 266, doi. 10.1046/j.1365-2249.2001.01512.x

By:

Giordanengo, L.;
Gea, S.;
Barbieri, G.;
Rabinovich, G. A.

Publication type:

Article

Soluble platelet selectin (sP-selectin) and soluble vascular cell adhesion molecule-1 (sVCAM-1) decrease during therapy with benznidazole in children with indeterminate form of Chagas' disease.

Published in:

Clinical & Experimental Immunology, 1999, v. 118, n. 3, p. 423, doi. 10.1046/j.1365-2249.1999.01070.x

By:

Laucella;
Segura;
Riarte;
Sosa, Estani S.;
Laucella, Susana

Publication type:

Article

Trypanosoma cruzi infection enhances polyreactive antibody response in an acute case of human Chagas' disease.

Published in:

Clinical & Experimental Immunology, 1993, v. 93, n. 1, p. 85, doi. 10.1111/1365-2249.ep15996271

By:

Grauert, M. R.;
Houdayer, M.;
Hontebeyrie-Joskowciz, M.

Publication type:

Article

Toxic side effects of drugs used to treat Chagas' disease (American trypanosomiasis).

Published in:

Human & Experimental Toxicology, 2006, v. 25, n. 8, p. 471, doi. 10.1191/0960327106het653oa

By:

Castro, José A;
de Mecca, María Montalto;
Bartel, Laura C

Publication type:

Article

Longitudinal follow up of serological response in children treated for Chagas disease.

Published in:

PLoS Neglected Tropical Diseases, 2019, v. 13, n. 8, p. 1, doi. 10.1371/journal.pntd.0007668

By:

Moscatelli, Guillermo;
Moroni, Samanta;
García Bournissen, Facundo;
González, Nicolás;
Ballering, Griselda;
Schijman, Alejandro;
Corral, Ricardo;
Bisio, Margarita;
Freilij, Héctor;
Altcheh, Jaime

Publication type:

Article

Negligible exposure to nifurtimox through breast milk during maternal treatment for Chagas Disease.

Published in:

PLoS Neglected Tropical Diseases, 2019, v. 13, n. 8, p. 1, doi. 10.1371/journal.pntd.0007647

By:

Moroni, Samanta;
Marson, Maria Elena;
Moscatelli, Guillermo;
Mastrantonio, Guido;
Bisio, Margarita;
Gonzalez, Nicolas;
Ballering, Griselda;
Altcheh, Jaime;
García-Bournissen, Facundo

Publication type:

Article

TGF-β inhibitor therapy decreases fibrosis and stimulates cardiac improvement in a pre-clinical study of chronic Chagas’ heart disease.

Published in:

PLoS Neglected Tropical Diseases, 2019, v. 13, n. 7, p. 1, doi. 10.1371/journal.pntd.0007602

By:

Ferreira, Roberto Rodrigues;
Abreu, Rayane da Silva;
Vilar-Pereira, Glaucia;
Degrave, Wim;
Meuser-Batista, Marcelo;
Ferreira, Nilma Valéria Caldeira;
da Cruz Moreira, Otacílio;
da Silva Gomes, Natália Lins;
Mello de Souza, Elen;
Ramos, Isalira P.;
Bailly, Sabine;
Feige, Jean-Jacques;
Lannes-Vieira, Joseli;
de Araújo-Jorge, Tania C.;
Waghabi, Mariana Caldas

Publication type:

Article

Estimating the current burden of Chagas disease in Mexico: A systematic review and meta-analysis of epidemiological surveys from 2006 to 2017.

Published in:

PLoS Neglected Tropical Diseases, 2019, v. 13, n. 4, p. 1, doi. 10.1371/journal.pntd.0006859

By:

Arnal, Audrey;
Waleckx, Etienne;
Rico-Chávez, Oscar;
Herrera, Claudia;
Dumonteil, Eric

Publication type:

Article

Improved DNA extraction technique from clot for the diagnosis of Chagas disease.

Published in:

PLoS Neglected Tropical Diseases, 2019, v. 13, n. 1, p. 1, doi. 10.1371/journal.pntd.0007024

By:

Mayta, Holger;
Romero, Yomara K.;
Pando, Alejandra;
Verastegui, Manuela;
Tinajeros, Freddy;
Bozo, Ricardo;
Henderson-Frost, Josephine;
Colanzi, Rony;
Flores, Jorge;
Lerner, Richard;
Bern, Caryn;
Gilman, Robert H.;
null, null

Publication type:

Article

Exploring the parasite load and molecular diversity of Trypanosoma cruzi in patients with chronic Chagas disease from different regions of Brazil.

Published in:

PLoS Neglected Tropical Diseases, 2018, v. 12, n. 11, p. 1, doi. 10.1371/journal.pntd.0006939

By:

Rodrigues-dos-Santos, Ícaro;
Melo, Myllena F.;
de Castro, Liane;
Hasslocher-Moreno, Alejandro Marcel;
do Brasil, Pedro Emmanuel A. A.;
Silvestre de Sousa, Andréa;
Britto, Constança;
Moreira, Otacilio C.

Publication type:

Article

A decade of vector control activities: Progress and limitations of Chagas disease prevention in a region of Guatemala with persistent Triatoma dimidiata infestation.

Published in:

PLoS Neglected Tropical Diseases, 2018, v. 12, n. 11, p. 1, doi. 10.1371/journal.pntd.0006896

By:

Juarez, Jose G.;
Pennington, Pamela M.;
Bryan, Joe P.;
Klein, Robert E.;
Beard, Charles B.;
Berganza, Elsa;
Rizzo, Nidia;
Cordon-Rosales, Celia

Publication type:

Article