Works matching DE "TREATMENT of African trypanosomiasis"

Results: 74

Towards Point-of-Care Diagnostic and Staging Tools for Human African Trypanosomiaisis.

Published in:

Journal of Tropical Medicine (16879686), 2012, p. 1, doi. 10.1155/2012/340538

By:

Matovu, Enock;
Kazibwe, Anne Juliet;
Mugasa, Claire Mack;
Ndungu, Joseph Mathu;
Njiru, Zablon Kithingi

Publication type:

Article

Evaluation of Methanol Root Extract of Securidaca longipedunculata for Antitrypanosomal Activity in vitro and in vivo.

Published in:

Thai Journal of Pharmaceutical Sciences, 2015, v. 39, n. 4, p. 156

By:

Gabriel, Eke Ifeanyi;
Ebere, Ihedioha Thelma;
K., Ejimofor Favour;
Onyema, Ezeh Ikenna;
Adaku, Ezeudu Terry;
Uchenna, Eze Ukamaka;
Nwabuisi, Okoye Chidozie;
Otah, Anaga Aruh

Publication type:

Article

Heat shock and awe.

Published in:

Nature Medicine, 2011, v. 17, n. 6, p. 646, doi. 10.1038/nm0611-646

By:

Dolgin, Elie;
Motluk, Alison

Publication type:

Article

Resurrecting the resurrection drug.

Published in:

Nature Medicine, 2002, v. 8, n. 9, p. 908, doi. 10.1038/nm0902-908b

By:

Wickware, Potter

Publication type:

Article

Expression of interferon-inducible chemokines and sleep/wake changes during early encephalitis in experimental African trypanosomiasis.

Published in:

PLoS Neglected Tropical Diseases, 2017, v. 11, n. 8, p. 1, doi. 10.1371/journal.pntd.0005854

By:

Laperchia, Claudia;
Tesoriero, Chiara;
Seke-Etet, Paul F.;
La Verde, Valentina;
Colavito, Valeria;
Grassi-Zucconi, Gigliola;
Rodgers, Jean;
Montague, Paul;
Kennedy, Peter G. E.;
Bentivoglio, Marina

Publication type:

Article

Introducing the TrypanoGEN biobank: A valuable resource for the elimination of human African trypanosomiasis.

Published in:

PLoS Neglected Tropical Diseases, 2017, v. 11, n. 6, p. 1, doi. 10.1371/journal.pntd.0005438

By:

Ilboudo, Hamidou;
Noyes, Harry;
Mulindwa, Julius;
Kimuda, Magambo Phillip;
Koffi, Mathurin;
Kaboré, Justin Windingoudi;
Ahouty, Bernadin;
Ngoyi, Dieudonné Mumba;
Fataki, Olivier;
Simo, Gustave;
Ofon, Elvis;
Enyaru, John;
Chisi, John;
Kamoto, Kelita;
Simuunza, Martin;
Alibu, Vincent P.;
Lejon, Veerle;
Jamonneau, Vincent;
Macleod, Annette;
Camara, Mamadou

Publication type:

Article

Genetic diversity and population structure of the tsetse fly Glossina fuscipes fuscipes (Diptera: Glossinidae) in Northern Uganda: Implications for vector control.

Published in:

PLoS Neglected Tropical Diseases, 2017, v. 11, n. 4, p. 1, doi. 10.1371/journal.pntd.0005485

By:

Opiro, Robert;
Saarman, Norah P.;
Echodu, Richard;
Opiyo, Elizabeth A.;
Dion, Kirstin;
Halyard, Alexis;
Dunn, Augustine W.;
Aksoy, Serap;
Caccone, Adalgisa

Publication type:

Article

Selective inhibition of RNA polymerase I transcription as a potential approach to treat African trypanosomiasis.

Published in:

PLoS Neglected Tropical Diseases, 2017, v. 11, n. 3, p. 1, doi. 10.1371/journal.pntd.0005432

By:

Kerry, Louise E.;
Pegg, Elaine E.;
Cameron, Donald P.;
Budzak, James;
Poortinga, Gretchen;
Hannan, Kate;
Hannan, Ross D.;
Rudenko, Gloria

Publication type:

Article

Predicting the Impact of Intervention Strategies for Sleeping Sickness in Two High-Endemicity Health Zones of the Democratic Republic of Congo.

Published in:

PLoS Neglected Tropical Diseases, 2017, v. 11, n. 1, p. 1, doi. 10.1371/journal.pntd.0005162

By:

Rock, Kat S.;
Keeling, Matt J.;
Torr, Steve J.;
Lumbala, Crispin

Publication type:

Article

Trypanosoma brucei Invasion and T-cell Infiltration of the Brain Parenchyma in Experimental Sleeping Sickness: Timing and Correlation with Functional Changes.

Published in:

PLoS Neglected Tropical Diseases, 2016, v. 10, n. 12, p. 1, doi. 10.1371/journal.pntd.0005242

By:

Laperchia, Claudia;
Palomba, Maria;
Seke Etet, Paul F.;
Rodgers, Jean;
Bradley, Barbara;
Montague, Paul;
Grassi-Zucconi, Gigliola;
Kennedy, Peter G. E.;
Bentivoglio, Marina

Publication type:

Article

Hit-to-Lead Development of the Chamigrane Endoperoxide Merulin A for the Treatment of African Sleeping Sickness.

Published in:

PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0046172

By:

Navarro, Gabriel;
Chokpaiboon, Supchar;
De Muylder, Geraldine;
Bray, Walter M.;
Nisam, Sean C.;
Mckerrow, James H.;
Pudhom, Khanitha;
Linington, Roger G.;
Bisser, Sylvie

Publication type:

Article

End in sight for sleeping sickness.

Published in:

Chemistry & Industry, 2011, n. 13, p. 6

By:

O'Driscoll, Cath

Publication type:

Article

African Trypanosomiasis-Associated Anemia: The Contribution of the Interplay between Parasites and the Mononuclear Phagocyte System.

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.00218

By:

Stijlemans, Benoit;
De Baetselier, Patrick;
Magez, Stefan;
Van Ginderachter, Jo A.;
De Trez, Carl

Publication type:

Article

Promising Leishmaniasis Drug.

Published in:: JAMA: Journal of the American Medical Association, 2012, v. 307, n. 11, p. 1129, doi. 10.1001/jama.2012.295
Publication type:: Article

Nifurtimox-Eflornithine Combination Therapy for Second-Stage Gambiense Human African Trypanosomiasis: Médecins Sans Frontières Experience in the Democratic Republic of the Congo.

Published in:

Clinical Infectious Diseases, 2013, v. 56, n. 2, p. 195, doi. 10.1093/cid/cis886

By:

Alirol, Emilie;
Schrumpf, David;
Amici Heradi, Josué;
Riedel, Andrea;
de Patoul, Catherine;
Quere, Michel;
Chappuis, François

Publication type:

Article

Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis.

Published in:

Brain: A Journal of Neurology, 2009, v. 132, n. 5, p. 1259, doi. 10.1093/brain/awp074

By:

Rodgers, Jean;
Stone, Trevor W.;
Barrett, Michael P.;
Bradley, Barbara;
Kennedy, Peter G. E.

Publication type:

Article

Parasite infection: Understanding drug mechanisms of action.

Published in:

Nature Reviews Drug Discovery, 2012, v. 11, n. 3, p. 190, doi. 10.1038/nrd3692

By:

Harrison, Charlotte

Publication type:

Article

In brief.

Published in:: 2010
Publication type:: Abstract

Monitoring the use of nifurtimox-eflornithine combination therapy (NECT) in the treatment of second stage gambiense human African trypanosomiasis.

Published in:

Research & Reports in Tropical Medicine, 2012, v. 3, p. 93, doi. 10.2147/rrtm.s34399

By:

Franco, Jose R.;
Simarro, Pere P.;
Diarra, Abdoulaye;
Ruiz-Postigo, Jose A.;
Samo, Mireille;
Jannin, Jean G.

Publication type:

Article

Chemotherapy of Human African Trypanosomiasis.

Published in:

Interdisciplinary Perspectives on Infectious Diseases, 2009, p. 1, doi. 10.1155/2009/195040

By:

Bacchi, Cyrus J.

Publication type:

Article

Organic cation transporter 1 (OCT1) is involved in pentamidine transport at the human and mouse blood-brain barrier (BBB).

Published in:

PLoS ONE, 2017, v. 12, n. 3, p. 1, doi. 10.1371/journal.pone.0173474

By:

Sekhar, Gayathri N.;
Georgian, Ana R.;
Sanderson, Lisa;
Vizcay-Barrena, Gema;
Brown, Rachel C.;
Muresan, Paula;
Fleck, Roland A.;
Thomas, Sarah A.

Publication type:

Article

Host-parasite co-metabolic activation of antitrypanosomal aminomethyl-benzoxaboroles.

Published in:

PLoS Pathogens, 2018, v. 14, n. 2, p. 1, doi. 10.1371/journal.ppat.1006850

By:

Zhang, Ning;
Zoltner, Martin;
Leung, Ka-Fai;
Scullion, Paul;
Hutchinson, Sebastian;
del Pino, Ricardo C.;
Vincent, Isabel M.;
Zhang, Yong-Kang;
Freund, Yvonne R.;
Alley, Michael R. K.;
Jacobs, Robert T.;
Read, Kevin D.;
Barrett, Michael P.;
Horn, David;
Field, Mark C.

Publication type:

Article

Immunobiology of African Trypanosomes: Need of Alternative Interventions.

Published in:

Journal of Biomedicine & Biotechnology, 2010, p. 1, doi. 10.1155/2010/389153

By:

Baral, Toya Nath

Publication type:

Article

Molecular mechanisms and therapeutic approaches to the treatment of African Trypanosomiasis.

Published in:

Drug Invention Today, 2012, v. 4, n. 5, p. 381

By:

Natuva, D. P.;
Brahmani, S.;
Subbarao, K.;
Padma, B.;
Anil, B.;
Koppulo, Sunilbabu;
Rao, Ch Babu

Publication type:

Article

Factory Tsetse Flies Must Behave Like Wild Flies: A Prerequisite for the Sterile Insect Technique.

Published in:

2011

By:

Vreysen, Marc J. B.;
Saleh, Khalfan M.;
Lancelot, Renaud;
Bouyer, Jérémy

Publication type:

Opinion

Fexinidazole - A New Oral Nitroimidazole Drug Candidate Entering Clinical Development for the Treatment of Sleeping Sickness.

Published in:

PLoS Neglected Tropical Diseases, 2010, v. 4, n. 12, p. 1, doi. 10.1371/journal.pntd.0000923

By:

Torreele, Els;
Trunz, Bernadette Bourdin;
Tweats, David;
Kaiser, Marcel;
Brun, Reto;
Guy Mazué;
Bray, Michael A.;
Bernard Pécoul

Publication type:

Article

Bayesian Geostatistical Analysis and Prediction of Rhodesian Human African Trypanosomiasis.

Published in:

PLoS Neglected Tropical Diseases, 2010, v. 4, n. 12, p. 1, doi. 10.1371/journal.pntd.0000914

By:

Wardrop, Nicola A.;
Atkinson, Peter M.;
Gething, Peter W.;
Fèvre, Eric M.;
Picozzi, Kim;
Kakembo, Abbas S. L.;
Welburn, Susan C.

Publication type:

Article

Novel Naphthalene-Based Inhibitors of Trypanosoma brucei RNA Editing Ligase 1.

Published in:

PLoS Neglected Tropical Diseases, 2010, v. 4, n. 8, p. 1, doi. 10.1371/journal.pntd.0000803

By:

Durrant, Jacob D.;
Hall, Laurence;
Swift, Robert V.;
Landon, Melissa;
Schnaufer, Achim;
Rommie E. Amaro

Publication type:

Article

NECT Is Next: Implementing the New Drug Combination Therapy for Trypanosoma brucei gambiense Sleeping Sickness.

Published in:

2010

By:

Yun, Oliver;
Priotto, Gerardo;
Tong, Jacqueline;
Flevaud, Laurence;
Chappuis, François

Publication type:

Opinion

Diverse Effects on Mitochondrial and Nuclear Functions Elicited by Drugs and Genetic Knockdowns in Bloodstream Stage Trypanosoma brucei.

Published in:

PLoS Neglected Tropical Diseases, 2010, v. 4, n. 5, p. 1, doi. 10.1371/journal.pntd.0000678

By:

Worthen, Christal;
Jensen, Bryan C.;
Parsons, Marilyn

Publication type:

Article

Controlling Sleeping Sickness--"When Will They Ever Learn?".

Published in:

2010

By:

Molyneux, David;
Ndung'u, Joseph;
Maudlin, Ian

Publication type:

Opinion

Novel Markers for Treatment Outcome in Late-Stage Trypanosoma brucei gambiense Trypanosomiasis.

Published in:

Clinical Infectious Diseases, 2008, v. 47, n. 1, p. 15, doi. 10.1086/588668

By:

Lejon, Veerle;
Roger, Isabelle;
Ngoyi, Dieudonné Mumba;
Menten, Joris;
Robays, Jo;
N'Siesi, Francois X.;
Bisser, Sylvie;
Boelaert, Marleen;
Büscher, Philippe

Publication type:

Article

Melarsoprol-Free Drug Combinations for Second-Stage Gambian Sleeping Sickness: The Way to Go.

Published in:

2007

By:

Chappuis, François

Publication type:

Editorial

Three Drug Combinations for Late-Stage Trypanosoma brucei gambiense Sleeping Sickness: A Randomized Clinical Trial in Uganda.

Published in:

PLoS Clinical Trials, 2006, v. 3, n. 12, p. 0001, doi. 10.1371/journal.pctr.0010039

By:

Priotto, Gerardo;
Fogg, Carole;
Balasegaram, Manica;
Erphas, Olema;
Louga, Albino;
Checchi, Francesco;
Ghabri, Salah;
Piola, Patrice

Publication type:

Article

Potent Antitrypanosomal Activities of 3-Aminosteroids against African Trypanosomes: Investigation of Cellular Effects and of Cross-Resistance with Existing Drugs.

Published in:

Molecules, 2019, v. 24, n. 2, p. 268, doi. 10.3390/molecules24020268

By:

Nnadi, Charles O.;
Ebiloma, Godwin U.;
Black, Jennifer A.;
Nwodo, Ngozi J.;
Lemgruber, Leandro;
Schmidt, Thomas J.;
de Koning, Harry P.

Publication type:

Article

Benzoxaborole treatment perturbs S-adenosyl-L-methionine metabolism in Trypanosoma brucei.

Published in:

PLoS Neglected Tropical Diseases, 2018, v. 12, n. 5, p. 1, doi. 10.1371/journal.pntd.0006450

By:

Steketee, Pieter C.;
Vincent, Isabel M.;
Achcar, Fiona;
Giordani, Federica;
Kim, Dong-Hyun;
Creek, Darren J.;
Freund, Yvonne;
Jacobs, Robert;
Rattigan, Kevin;
Horn, David;
Field, Mark C.;
MacLeod, Annette;
Barrett, Michael P.

Publication type:

Article

Evaluation of the Trypanosoma brucei 6-oxopurine salvage pathway as a potential target for drug discovery.

Published in:

PLoS Neglected Tropical Diseases, 2018, v. 12, n. 2, p. 1, doi. 10.1371/journal.pntd.0006301

By:

Doleželová, Eva;
Terán, David;
Gahura, Ondřej;
Kotrbová, Zuzana;
Procházková, Michaela;
Keough, Dianne;
Špaček, Petr;
Hocková, Dana;
Guddat, Luke;
Zíková, Alena

Publication type:

Article

Updated estimate of the duration of the meningo-encephalitic stage in gambiense human African trypanosomiasis.

Published in:

BMC Research Notes, 2015, v. 8, n. 1, p. 1, doi. 10.1186/s13104-015-1244-3

By:

Checchi, Francesco;
Funk, Sebastian;
Chandramohan, Daniel;
Haydon, Daniel T.;
Chappuis, François

Publication type:

Article

Briefly.

Published in:

Canadian Medical Association Journal (CMAJ), 2009, v. 181, n. 10, p. E235, doi. 10.1503/cmaj.109-3077

By:

Collier, Roger;
Kondro, Wayne

Publication type:

Article

Trypanocidal and cytotoxic evaluation of synthesized thiosemicarbazones as potential drug leads against sleeping sickness.

Published in:

Molecular Biology Reports, 2014, v. 41, n. 3, p. 1617, doi. 10.1007/s11033-013-3008-2

By:

Glinma, Bienvenu;
Kpoviessi, Sika;
Gbaguidi, Fernand;
Kapanda, Coco;
Bero, Joanne;
Quetin-Leclercq, Joëlle;
Moudachirou, Mansourou;
Poupaert, Jacques;
Accrombessi, Georges;
Gachomo, Emma;
Baba-Moussa, Lamine;
Kotchoni, Simeon

Publication type:

Article

Treatment perspectives for human African trypanosomiasis.

Published in:

Fundamental & Clinical Pharmacology, 2003, v. 17, n. 2, p. 171, doi. 10.1046/j.1472-8206.2003.00167.x

By:

Bouteille, Bernard;
Oukem, Odile;
Bisser, Sylvie;
Dumas, Michel

Publication type:

Article

Neuropeptides kill African trypanosomes by targeting intracellular compartments and inducing autophagic-like cell death.

Published in:

Cell Death & Differentiation, 2009, v. 16, n. 3, p. 406, doi. 10.1038/cdd.2008.161

By:

Delgado, M.;
Anderson, P.;
Garcia-Salcedo, J. A.;
Caro, M.;
Gonzalez-Rey, E.

Publication type:

Article

Short-course eflornithine in Gambian trypanosomiasis: a multicentre randomized controlled trial.

Published in:

Bulletin of the World Health Organization, 2000, v. 78, n. 11, p. 1284

By:

Pepin, Jacques;
Khonde, Nzambi

Publication type:

Article

First Oral Sleeping Sickness Drug.

Published in:

2019

By:

Friedrich, M.J.

Publication type:

journal article

A mathematical model of a theoretical sleeping sickness vaccine.

Published in:

Mathematical Population Studies, 2016, v. 23, n. 2, p. 95, doi. 10.1080/08898480.2013.836427

By:

Samia, Yasmine;
Kealey, Alison;
Smith?, Robert J.

Publication type:

Article

Quantitative evaluation of the strategy to eliminate human African trypanosomiasis in the Democratic Republic of Congo.

Published in:

Parasites & Vectors, 2015, v. 8, n. 1, p. 1, doi. 10.1186/s13071-015-1131-8

By:

Rock, Kat S.;
Torr, Steve J.;
Lumbala, Crispin;
Keeling, Matt J.

Publication type:

Article

A luciferase based viability assay for ATP detection in 384-wellformat for high throughput whole cell screening of Trypanosomabrucei brucei bloodstream form strain 427.

Published in:: Parasites & Vectors, 2009, v. 2, n. 1, p. 54, doi. 10.1186/1756-3305-2-54
Publication type:: Article

Combination Therapy for Sleeping Sickness: A Wake-Up Call.

Published in:

2007

By:

Pepin, Jacques

Publication type:

Editorial

Novel therapeutic approach: organic arsenical (melarsoprol) alone or with all-trans -retinoic acid markedly inhibit growth of human breast and prostate cancer cells in vitro and in vivo.

Published in:

British Journal of Cancer, 2000, v. 82, n. 2, p. 452, doi. 10.1054/bjoc.1999.0942

By:

Koshiuka, K;
Elstner, E;
Williamson, E;
Said, J W;
Tada, Y;
Koeffler, H P

Publication type:

Article

Drugs and drug resistance.

Published in:: WHO Technical Report Series, 2012, n. 975, p. 43
Publication type:: Article