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A Mosaic Genetic Screen Reveals Distinct Roles for trithorax and Polycomb group Genes in Drosophila Eye Development.
Published in:
Genetics, 2004, v. 166, n. 1, p. 187, doi. 10.1534/genetics.166.1.187
By:
- Janody, Florence;
- Lee, Jeffrey D.;
- Jahren, Neal;
- Hazelett, Dennis J.;
- Benlali, Aude;
- Miura, Grant I.;
- Draskovic, Irena;
- Treisman, Jessica E.
Publication type:
Article
Diagnostic and therapeutic potential of RNASET2 in Crohn's disease: Disease-risk polymorphism modulates allelic-imbalance in expression and circulating protein levels and recombinant-RNASET2 attenuates pro-inflammatory cytokine secretion.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 01, doi. 10.3389/fimmu.2022.999155
By:
- Biener-Ramanujan, Eva;
- Rosier, Florian;
- Coetzee, Simon G.;
- McGovern, Dermot D. P.;
- Hazelett, Dennis;
- Targan, Stephan R.;
- Gonsky, Rivkah
Publication type:
Article
Enrichment of risk SNPs in regulatory regions implicate diverse tissues in Parkinson's disease etiology.
Published in:
Scientific Reports, 2016, p. 30509, doi. 10.1038/srep30509
By:
- Coetzee, Simon G.;
- Pierce, Steven;
- Brundin, Patrik;
- Brundin, Lena;
- Hazelett, Dennis J.;
- Coetzee, Gerhard A.
Publication type:
Article
Large Cancer Pedigree Involving Multiple Cancer Genes including Likely Digenic MSH2 and MSH6 Lynch Syndrome (LS) and an Instance of Recombinational Rescue from LS.
Published in:
Cancers, 2023, v. 15, n. 1, p. 228, doi. 10.3390/cancers15010228
By:
- Vogelaar, Ingrid P.;
- Greer, Stephanie;
- Wang, Fan;
- Shin, GiWon;
- Lau, Billy;
- Hu, Yajing;
- Haraldsdottir, Sigurdis;
- Alvarez, Rocio;
- Hazelett, Dennis;
- Nguyen, Peter;
- Aguirre, Francesca P.;
- Guindi, Maha;
- Hendifar, Andrew;
- Balcom, Jessica;
- Leininger, Anna;
- Fairbank, Beth;
- Ji, Hanlee;
- Hitchins, Megan P.
Publication type:
Article
Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer.
Published in:
Carcinogenesis, 2015, v. 36, n. 11, p. 1341, doi. 10.1093/carcin/bgv138
By:
- Lawrenson, Kate;
- Iversen, Edwin S.;
- Tyrer, Jonathan;
- Palmieri Weber, Rachel;
- Concannon, Patrick;
- Hazelett, Dennis J.;
- Qiyuan Li;
- Marks, Jeffrey R.;
- Berchuck, Andrew;
- Lee, Janet M.;
- Aben, Katja K. H.;
- Anton-Culver, Hoda;
- Antonenkova, Natalia;
- Bandera, Elisa V.;
- Bean, Yukie;
- Beckmann, Matthias W.;
- Bisogna, Maria;
- Bjorge, Line;
- Bogdanova, Natalia;
- Brinton, Louise A.
Publication type:
Article
Enrichment of putative PAX8 target genes at serous epithelial ovarian cancer susceptibility loci.
Published in:
2017
By:
- Kar, Siddhartha P;
- Adler, Emily;
- Tyrer, Jonathan;
- Hazelett, Dennis;
- Anton-Culver, Hoda;
- Bandera, Elisa V;
- Beckmann, Matthias W;
- Berchuck, Andrew;
- Bogdanova, Natalia;
- Brinton, Louise;
- Butzow, Ralf;
- Campbell, Ian;
- Carty, Karen;
- Chang-Claude, Jenny;
- Cook, Linda S;
- Cramer, Daniel W;
- Cunningham, Julie M;
- Dansonka-Mieszkowska, Agnieszka;
- Doherty, Jennifer Anne;
- Dörk, Thilo
Publication type:
journal article
Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions.
Published in:
Human Molecular Genetics, 2015, v. 24, n. 19, p. 5603, doi. 10.1093/hmg/ddv269
By:
- Ying Han;
- Hazelett, Dennis J.;
- Wiklund, Fredrik;
- Schumacher, Fredrick R.;
- Stram, Daniel O.;
- Berndt, Sonja I.;
- Zhaoming Wang;
- Rand, Kristin A.;
- Hoover, Robert N.;
- Machiela, Mitchell J.;
- Yeager, Merideth;
- Burdette, Laurie;
- Chung, Charles C.;
- Hutchinson, Amy;
- Yu, Kai;
- Jianfeng Xu;
- Travis, Ruth C.;
- Key, Timothy J.;
- Siddiq, Afshan;
- Canzian, Federico
Publication type:
Article
Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans.
Published in:
Human Molecular Genetics, 2015, v. 24, n. 19, p. 5589, doi. 10.1093/hmg/ddv203
By:
- Al Olama, Ali Amin;
- Dadaev, Tokhir;
- Hazelett, Dennis J.;
- Qiuyan Li;
- Leongamornlert, Daniel;
- Saunders, Edward J.;
- Stephens, Sarah;
- Cieza-Borrella, Clara;
- Whitmore, Ian;
- Garcia, Sara Benlloch;
- Giles, Graham G.;
- Southey, Melissa C.;
- Fitzgerald, Liesel;
- Gronberg, Henrik;
- Wiklund, Fredrik;
- Aly, Markus;
- Henderson, Brian E.;
- Schumacher, Fredrick;
- Haiman, Christopher A.;
- Schleutker, Johanna
Publication type:
Article
Cell-type-specific enrichment of risk-associated regulatory elements at ovarian cancer susceptibility loci.
Published in:
Human Molecular Genetics, 2015, v. 24, n. 13, p. 3595, doi. 10.1093/hmg/ddv101
By:
- Coetzee, Simon G.;
- Shen, Howard C.;
- Hazelett, Dennis J.;
- Lawrenson, Kate;
- Kuchenbaecker, Karoline;
- Tyrer, Jonathan;
- Rhie, Suhn K.;
- Levanon, Keren;
- Karst, Alison;
- Drapkin, Ronny;
- Ramus, Susan J.;
- Couch, Fergus J.;
- Offit, Kenneth;
- Chenevix-Trench, Georgia;
- Monteiro, Alvaro N. A.;
- Antoniou, Antonis;
- Freedman, Matthew;
- Coetzee, Gerhard A.;
- Pharoah, Paul D. P.;
- Noushmehr, Houtan
Publication type:
Article
CRISPR-mediated deletion of prostate cancer risk-associated CTCF loop anchors identifies repressive chromatin loops.
Published in:
Genome Biology, 2018, v. 19, n. 1, p. N.PAG, doi. 10.1186/s13059-018-1531-0
By:
- Guo, Yu;
- Perez, Andrew A.;
- Hazelett, Dennis J.;
- Coetzee, Gerhard A.;
- Rhie, Suhn Kyong;
- Farnham, Peggy J.
Publication type:
Article
GENAVi: a shiny web application for gene expression normalization, analysis and visualization.
Published in:
BMC Genomics, 2019, v. 20, n. 1, p. N.PAG, doi. 10.1186/s12864-019-6073-7
By:
- Reyes, Alberto Luiz P.;
- Silva, Tiago C.;
- Coetzee, Simon G.;
- Plummer, Jasmine T.;
- Davis, Brian D.;
- Chen, Stephanie;
- Hazelett, Dennis J.;
- Lawrenson, Kate;
- Berman, Benjamin P.;
- Gayther, Simon A.;
- Jones, Michelle R.
Publication type:
Article
Comprehensive Functional Annotation of 77 Prostate Cancer Risk Loci.
Published in:
PLoS Genetics, 2014, v. 10, n. 1, p. 1, doi. 10.1371/journal.pgen.1004102
By:
- Hazelett, Dennis J.;
- Rhie, Suhn Kyong;
- Gaddis, Malaina;
- Yan, Chunli;
- Lakeland, Daniel L.;
- Coetzee, Simon G.;
- Henderson, Brian E.;
- Noushmehr, Houtan;
- Cozen, Wendy;
- Kote-Jarai, Zsofia;
- Eeles, Rosalind A.;
- Easton, Douglas F.;
- Haiman, Christopher A.;
- Lu, Wange;
- Farnham, Peggy J.;
- Coetzee, Gerhard A.
Publication type:
Article
Circulating tumor DNA dynamics and response to immunotherapy in colorectal cancer.
Published in:
Molecular & Clinical Oncology, 2022, v. 16, n. 5, p. N.PAG, doi. 10.3892/mco.2022.2533
By:
- Gong, Jun;
- Aguirre, Francesca;
- Hazelett, Dennis;
- Alvarez, Rocio;
- Zhou, Lisa;
- Hendifar, Andrew;
- Osipov, Arsen;
- Zaghiyan, Karen;
- Cho, May;
- Gangi, Alexandra;
- Hitchins, Megan
Publication type:
Article
POLE-Mutant Colon Cancer Treated with PD-1 Blockade Showing Clearance of Circulating Tumor DNA and Prolonged Disease-Free Interval.
Published in:
Genes, 2023, v. 14, n. 5, p. 1054, doi. 10.3390/genes14051054
By:
- Bikhchandani, Mihir;
- Amersi, Farin;
- Hendifar, Andrew;
- Gangi, Alexandra;
- Osipov, Arsen;
- Zaghiyan, Karen;
- Atkins, Katelyn;
- Cho, May;
- Aguirre, Francesca;
- Hazelett, Dennis;
- Alvarez, Rocio;
- Zhou, Lisa;
- Hitchins, Megan;
- Gong, Jun
Publication type:
Article
Nucleosome positioning and histone modifications define relationships between regulatory elements and nearby gene expression in breast epithelial cells.
Published in:
BMC Genomics, 2014, v. 15, n. 1, p. 1, doi. 10.1186/1471-2164-15-331
By:
- Suhn Kyong Rhie;
- Hazelett, Dennis J.;
- Coetzee, Simon G.;
- Yan, Chunli;
- Noushmehr, Houtan;
- Coetzee, Gerhard A.
Publication type:
Article
ELMER v.2: an R/Bioconductor package to reconstruct gene regulatory networks from DNA methylation and transcriptome profiles.
Published in:
Bioinformatics, 2019, v. 35, n. 11, p. 1974, doi. 10.1093/bioinformatics/bty902
By:
- Silva, Tiago C;
- Coetzee, Simon G;
- Gull, Nicole;
- Yao, Lijing;
- Hazelett, Dennis J;
- Noushmehr, Houtan;
- Lin, De-Chen;
- Berman, Benjamin P
Publication type:
Article
motifbreakR: an R/Bioconductor package for predicting variant effects at transcription factor binding sites.
Published in:
Bioinformatics, 2015, v. 31, n. 23, p. 3847, doi. 10.1093/bioinformatics/btv470
By:
- Coetzee, Simon G.;
- Coetzee, Gerhard A.;
- Hazelett, Dennis J.
Publication type:
Article
Affinity Density: a novel genomic approach to the identification of transcription factor regulatory targets.
Published in:
Bioinformatics, 2009, v. 25, n. 13, p. 1617, doi. 10.1093/bioinformatics/btp282
By:
- Dennis J. Hazelett;
- Daniel L. Lakeland;
- Joseph B. Weiss
Publication type:
Article
Two Novel Susceptibility Loci for Prostate Cancer in Men of African Ancestry.
Published in:
2017
By:
- Conti, David V.;
- Kan Wang;
- Xin Sheng;
- Bensen, Jeannette T.;
- Hazelett, Dennis J.;
- Cook, Michael B.;
- Ingles, Sue A.;
- Kittles, Rick A.;
- Strom, Sara S.;
- Rybicki, Benjamin A.;
- Nemesure, Barbara;
- Isaacs, William B.;
- Stanford, Janet L.;
- Wei Zheng;
- Sanderson, Maureen;
- John, Esther M.;
- Park, Jong Y.;
- Jianfeng Xu;
- Stevens, Victoria L.;
- Berndt, Sonja I.
Publication type:
journal article
Prostate Cancer Susceptibility in Men of African Ancestry at 8q24.
Published in:
2016
By:
- Ying Han;
- Rand, Kristin A.;
- Hazelett, Dennis J.;
- Ingles, Sue A.;
- Kittles, Rick A.;
- Strom, Sara S.;
- Rybicki, Benjamin A.;
- Nemesure, Barbara;
- Isaacs, William B.;
- Stanford, Janet L.;
- Wei Zheng;
- Schumacher, Fredrick R.;
- Berndt, Sonja I.;
- Zhaoming Wang;
- Jianfeng Xu;
- Rohland, Nadin;
- Reich, David;
- Tandon, Arti;
- Pasaniuc, Bogdan;
- Allen, Alex
Publication type:
journal article
Non-coding somatic mutations converge on the PAX8 pathway in ovarian cancer.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15951-0
By:
- Corona, Rosario I.;
- Seo, Ji-Heui;
- Lin, Xianzhi;
- Hazelett, Dennis J.;
- Reddy, Jessica;
- Fonseca, Marcos A. S.;
- Abassi, Forough;
- Lin, Yvonne G.;
- Mhawech-Fauceglia, Paulette Y.;
- Shah, Sohrab P.;
- Huntsman, David G.;
- Gusev, Alexander;
- Karlan, Beth Y.;
- Berman, Benjamin P.;
- Freedman, Matthew L.;
- Gayther, Simon A.;
- Lawrenson, Kate
Publication type:
Article

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