Works matching IS 1553734X AND DT 2016 AND VI 12 AND IP 4

Results: 59

A Drug-Centric View of Drug Development: How Drugs Spread from Disease to Disease.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004852

By:

Rodriguez-Esteban, Raul

Publication type:

Article

Principles and Overview of Sampling Methods for Modeling Macromolecular Structure and Dynamics.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004619

By:

Maximova, Tatiana;
Moffatt, Ryan;
Ma, Buyong;
Nussinov, Ruth;
Shehu, Amarda

Publication type:

Article

Reconstruction of Cell Surface Densities of Ion Pumps, Exchangers, and Channels from mRNA Expression, Conductance Kinetics, Whole-Cell Calcium, and Current-Clamp Voltage Recordings, with an Application to Human Uterine Smooth Muscle Cells.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004828

By:

Atia, Jolene;
McCloskey, Conor;
Shmygol, Anatoly S.;
Rand, David A.;
van den Berg, Hugo A.;
Blanks, Andrew M.

Publication type:

Article

Quorum-Sensing Synchronization of Synthetic Toggle Switches: A Design Based on Monotone Dynamical Systems Theory.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004881

By:

Nikolaev, Evgeni V.;
Sontag, Eduardo D.

Publication type:

Article

A Network Biology Approach Identifies Molecular Cross-Talk between Normal Prostate Epithelial and Prostate Carcinoma Cells.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004884

By:

Trevino, Victor;
Cassese, Alberto;
Nagy, Zsuzsanna;
Zhuang, Xiaodong;
Herbert, John;
Antzack, Philipp;
Clarke, Kim;
Davies, Nicholas;
Rahman, Ayesha;
Campbell, Moray J.;
Guindani, Michele;
Bicknell, Roy;
Vannucci, Marina;
Falciani, Francesco

Publication type:

Article

HepatoDyn: A Dynamic Model of Hepatocyte Metabolism That Integrates <sup>13</sup>C Isotopomer Data.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004899

By:

Foguet, Carles;
Marin, Silvia;
Selivanov, Vitaly A.;
Fanchon, Eric;
Lee, Wai-Nang Paul;
Guinovart, Joan J.;
de Atauri, Pedro;
Cascante, Marta

Publication type:

Article

The Interaction between Vector Life History and Short Vector Life in Vector-Borne Disease Transmission and Control.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004837

By:

Brand, Samuel P. C.;
Rock, Kat S.;
Keeling, Matt J.

Publication type:

Article

Deep Neural Networks as a Computational Model for Human Shape Sensitivity.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004896

By:

Kubilius, Jonas;
Bracci, Stefania;
Op de Beeck, Hans P.

Publication type:

Article

Single-Cell Co-expression Analysis Reveals Distinct Functional Modules, Co-regulation Mechanisms and Clinical Outcomes.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004892

By:

Wang, Jie;
Xia, Shuli;
Arand, Brian;
Zhu, Heng;
Machiraju, Raghu;
Huang, Kun;
Ji, Hongkai;
Qian, Jiang

Publication type:

Article

A Geometrically-Constrained Mathematical Model of Mammary Gland Ductal Elongation Reveals Novel Cellular Dynamics within the Terminal End Bud.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004839

By:

Paine, Ingrid;
Chauviere, Arnaud;
Landua, John;
Sreekumar, Amulya;
Cristini, Vittorio;
Rosen, Jeffrey;
Lewis, Michael T.

Publication type:

Article

Nucleosome Presence at AML-1 Binding Sites Inversely Correlates with Ly49 Expression: Revelations from an Informatics Analysis of Nucleosomes and Immune Cell Transcription Factors.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004894

By:

Wight, Andrew;
Yang, Doo;
Ioshikhes, Ilya;
Makrigiannis, Andrew P.

Publication type:

Article

Bulk Genotyping of Biopsies Can Create Spurious Evidence for Hetereogeneity in Mutation Content.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004413

By:

Kostadinov, Rumen;
Maley, Carlo C.;
Kuhner, Mary K.

Publication type:

Article

MEDYAN: Mechanochemical Simulations of Contraction and Polarity Alignment in Actomyosin Networks.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004877

By:

Popov, Konstantin;
Komianos, James;
Papoian, Garegin A.

Publication type:

Article

Parasites Sustain and Enhance RNA-Like Replicators through Spatial Self-Organisation.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004902

By:

Colizzi, Enrico Sandro;
Hogeweg, Paulien

Publication type:

Article

The Evolution of Quorum Sensing as a Mechanism to Infer Kinship.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004848

By:

Schluter, Jonas;
Schoech, Armin P.;
Foster, Kevin R.;
Mitri, Sara

Publication type:

Article

An Electrostatic Funnel in the GABA-Binding Pathway.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004831

By:

Carpenter, Timothy S.;
Lightstone, Felice C.

Publication type:

Article

Rigid Residue Scan Simulations Systematically Reveal Residue Entropic Roles in Protein Allostery.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004893

By:

Kalescky, Robert;
Zhou, Hongyu;
Liu, Jin;
Tao, Peng

Publication type:

Article

Constraints on Biological Mechanism from Disease Comorbidity Using Electronic Medical Records and Database of Genetic Variants.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004885

By:

Bagley, Steven C.;
Sirota, Marina;
Chen, Richard;
Butte, Atul J.;
Altman, Russ B.

Publication type:

Article

Modularity Induced Gating and Delays in Neuronal Networks.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004883

By:

Shein-Idelson, Mark;
Cohen, Gilad;
Ben-Jacob, Eshel;
Hanein, Yael

Publication type:

Article

CNVkit: Genome-Wide Copy Number Detection and Visualization from Targeted DNA Sequencing.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004873

By:

Talevich, Eric;
Shain, A. Hunter;
Botton, Thomas;
Bastian, Boris C.

Publication type:

Article

The Role of Genome Accessibility in Transcription Factor Binding in Bacteria.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004891

By:

Gomes, Antonio L. C.;
Wang, Harris H.

Publication type:

Article

Network-Based Interpretation of Diverse High-Throughput Datasets through the Omics Integrator Software Package.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004879

By:

Tuncbag, Nurcan;
Gosline, Sara J. C.;
Kedaigle, Amanda;
Soltis, Anthony R.;
Gitter, Anthony;
Fraenkel, Ernest

Publication type:

Article

A Computational Model of the Rainbow Trout Hypothalamus-Pituitary-Ovary-Liver Axis.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004874

By:

Gillies, Kendall;
Krone, Stephen M.;
Nagler, James J.;
Schultz, Irvin R.

Publication type:

Article

Effective Design of Multifunctional Peptides by Combining Compatible Functions.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004786

By:

Diener, Christian;
Garza Ramos Martínez, Georgina;
Moreno Blas, Daniel;
Castillo González, David A.;
Corzo, Gerardo;
Castro-Obregon, Susana;
Del Rio, Gabriel

Publication type:

Article

Rapid Prediction of Bacterial Heterotrophic Fluxomics Using Machine Learning and Constraint Programming.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004838

By:

Wu, Stephen Gang;
Wang, Yuxuan;
Jiang, Wu;
Oyetunde, Tolutola;
Yao, Ruilian;
Zhang, Xuehong;
Shimizu, Kazuyuki;
Tang, Yinjie J.;
Bao, Forrest Sheng

Publication type:

Article

Integrating Antimicrobial Therapy with Host Immunity to Fight Drug-Resistant Infections: Classical vs. Adaptive Treatment.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004857

By:

Gjini, Erida;
Brito, Patricia H.

Publication type:

Article

Computational Reconstruction of NFκB Pathway Interaction Mechanisms during Prostate Cancer.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004820

By:

Börnigen, Daniela;
Tyekucheva, Svitlana;
Wang, Xiaodong;
Rider, Jennifer R.;
Lee, Gwo-Shu;
Mucci, Lorelei A.;
Sweeney, Christopher;
Huttenhower, Curtis

Publication type:

Article

A Predictive Model for Yeast Cell Polarization in Pheromone Gradients.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004795

By:

Muller, Nicolas;
Piel, Matthieu;
Calvez, Vincent;
Voituriez, Raphaël;
Gonçalves-Sá, Joana;
Guo, Chin-Lin;
Jiang, Xingyu;
Murray, Andrew;
Meunier, Nicolas

Publication type:

Article

Ups and Downs of Poised RNA Polymerase II in B-Cells.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004821

By:

Dao, Phuong;
Wojtowicz, Damian;
Nelson, Steevenson;
Levens, David;
Przytycka, Teresa M.

Publication type:

Article

Hippocampal CA1 Ripples as Inhibitory Transients.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004880

By:

Malerba, Paola;
Krishnan, Giri P;
Fellous, Jean-Marc;
Bazhenov, Maxim

Publication type:

Article

APP Is a Context-Sensitive Regulator of the Hippocampal Presynaptic Active Zone.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004832

By:

Laßek, Melanie;
Weingarten, Jens;
Wegner, Martin;
Mueller, Benjamin F.;
Rohmer, Marion;
Baeumlisberger, Dominic;
Arrey, Tabiwang N.;
Hick, Meike;
Ackermann, Jörg;
Acker-Palmer, Amparo;
Koch, Ina;
Müller, Ulrike;
Karas, Michael;
Volknandt, Walter

Publication type:

Article

Oscillations via Spike-Timing Dependent Plasticity in a Feed-Forward Model.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004878

By:

Luz, Yotam;
Shamir, Maoz

Publication type:

Article

Visualization of Metabolic Interaction Networks in Microbial Communities Using VisANT 5.0.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004875

By:

Granger, Brian R.;
Chang, Yi-Chien;
Wang, Yan;
DeLisi, Charles;
Segrè, Daniel;
Hu, Zhenjun

Publication type:

Article

AuPairWise: A Method to Estimate RNA-Seq Replicability through Co-expression.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004868

By:

Ballouz, Sara;
Gillis, Jesse

Publication type:

Article

Mathematical Model for Length Control by the Timing of Substrate Switching in the Type III Secretion System.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004851

By:

Nariya, Maulik K.;
Israeli, Johnny;
Shi, Jack J.;
Deeds, Eric J.

Publication type:

Article

The Development of Audio-Visual Integration for Temporal Judgements.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004865

By:

Adams, Wendy J.

Publication type:

Article

Problem Solving as Probabilistic Inference with Subgoaling: Explaining Human Successes and Pitfalls in the Tower of Hanoi.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004864

By:

Donnarumma, Francesco;
Maisto, Domenico;
Pezzulo, Giovanni

Publication type:

Article

Computational and Empirical Studies Predict Mycobacterium tuberculosis-Specific T Cells as a Biomarker for Infection Outcome.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004804

By:

Marino, Simeone;
Gideon, Hannah P.;
Gong, Chang;
Mankad, Shawn;
McCrone, John T.;
Lin, Philana Ling;
Linderman, Jennifer J.;
Flynn, JoAnne L.;
Kirschner, Denise E.

Publication type:

Article

A Knowledge-Based System for Display and Prediction of O-Glycosylation Network Behaviour in Response to Enzyme Knockouts.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004844

By:

McDonald, Andrew G.;
Tipton, Keith F.;
Davey, Gavin P.

Publication type:

Article

Cache Domains That are Homologous to, but Different from PAS Domains Comprise the Largest Superfamily of Extracellular Sensors in Prokaryotes.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004862

By:

Upadhyay, Amit A.;
Fleetwood, Aaron D.;
Adebali, Ogun;
Finn, Robert D.;
Zhulin, Igor B.

Publication type:

Article

Maximum-Entropy Models of Sequenced Immune Repertoires Predict Antigen-Antibody Affinity.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004870

By:

Asti, Lorenzo;
Uguzzoni, Guido;
Marcatili, Paolo;
Pagnani, Andrea

Publication type:

Article

Mechanical Stress Induces Remodeling of Vascular Networks in Growing Leaves.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004819

By:

Bar-Sinai, Yohai;
Julien, Jean-Daniel;
Sharon, Eran;
Armon, Shahaf;
Nakayama, Naomi;
Adda-Bedia, Mokhtar;
Boudaoud, Arezki

Publication type:

Article

Quorum Sensing Desynchronization Leads to Bimodality and Patterned Behaviors.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004781

By:

Quan, David N.;
Tsao, Chen-Yu;
Wu, Hsuan-Chen;
Bentley, William E.

Publication type:

Article

Molecular Infectious Disease Epidemiology: Survival Analysis and Algorithms Linking Phylogenies to Transmission Trees.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004869

By:

Kenah, Eben;
Britton, Tom;
Halloran, M. Elizabeth;
JrLongini, Ira M.

Publication type:

Article

Traveling Pulses for a Two-Species Chemotaxis Model.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004843

By:

Emako, Casimir;
Gayrard, Charlène;
Buguin, Axel;
Neves de Almeida, Luís;
Vauchelet, Nicolas

Publication type:

Article

Fast and Accurate Learning When Making Discrete Numerical Estimates.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004859

By:

Sanborn, Adam N.;
Beierholm, Ulrik R.

Publication type:

Article

A Robust Feedforward Model of the Olfactory System.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004850

By:

Zhang, Yilun;
Sharpee, Tatyana O.

Publication type:

Article

Identifying Malaria Transmission Foci for Elimination Using Human Mobility Data.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004846

By:

Ruktanonchai, Nick W.;
DeLeenheer, Patrick;
Tatem, Andrew J.;
Alegana, Victor A.;
Caughlin, T. Trevor;
zu Erbach-Schoenberg, Elisabeth;
Lourenço, Christopher;
Ruktanonchai, Corrine W.;
Smith, David L.

Publication type:

Article

Detecting Presymptomatic Infection Is Necessary to Forecast Major Epidemics in the Earliest Stages of Infectious Disease Outbreaks.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004836

By:

Thompson, Robin N.;
Gilligan, Christopher A.;
Cunniffe, Nik J.

Publication type:

Article

A Theoretical Model of Jigsaw-Puzzle Pattern Formation by Plant Leaf Epidermal Cells.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004833

By:

Higaki, Takumi;
Kutsuna, Natsumaro;
Akita, Kae;
Takigawa-Imamura, Hisako;
Yoshimura, Kenji;
Miura, Takashi

Publication type:

Article