Works matching DE "AP-1 transcription factor"

Results: 375

Multiomic analysis of human kidney disease identifies a tractable inflammatory and pro-fibrotic tubular cell phenotype.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-59997-4

By:

Reck, Maximilian;
Baird, David P.;
Veizades, Stefan;
Sutherland, Callum;
Bell, Rachel M. B.;
Hur, Heeyoun;
Cairns, Carolynn;
Janas, Piotr P.;
Campbell, Ross;
Nam, Andy;
Yang, Wei;
Schurman, Nathan;
Williams, Claire;
O'Sullivan, Eoin;
Beniazza, Meryam;
Corsinotti, Andrea;
Bellamy, Christopher;
Hughes, Jeremy;
Laird, Alexander;
Denby, Laura

Publication type:

Article

The Activation of the CCND1 Promoter by AP-1 and SOX Transcription Factors in PC3 Prostate Cancer Cells Can Be Prevented by Anacardic Acid Analogs.

Published in:

Cell Biochemistry & Biophysics, 2025, v. 83, n. 2, p. 2349, doi. 10.1007/s12013-024-01646-6

By:

Brunie, Manon;
Robichaud, Mika A.;
Touaibia, Mohamed;
Martin, Luc J.

Publication type:

Article

Prmt1-mediated methylation regulates Ncoa4 stability to transactivate Adamts genes and promote bone extracellular matrix degradation in chronic hematogenous osteomyelitis.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00652-9

By:

Chen, Xun;
Duan, Ning;
Zhang, Wentao;
Song, Tao;
Cong, Fei

Publication type:

Article

Activator protein‐1 mediated CYP6ER1 overexpression in the clothianidin resistance of Nilaparvata lugens (Stål).

Published in:

Pest Management Science, 2021, v. 77, n. 10, p. 4476, doi. 10.1002/ps.6482

By:

Jin, Ruoheng;
Wang, Yue;
He, Biyan;
Zhang, Yunhua;
Cai, Tingwei;
Wan, Hu;
Jin, Byung Rae;
Li, Jianhong

Publication type:

Article

A microRNA Arising from the Negative Strand of SARS-CoV-2 Genome Targets FOS to Reduce AP-1 Activity.

Published in:

Non-Coding RNA, 2023, v. 9, n. 3, p. 33, doi. 10.3390/ncrna9030033

By:

Greco, Francesco;
Lorefice, Elisa;
Carissimi, Claudia;
Laudadio, Ilaria;
Ciccosanti, Fabiola;
Di Rienzo, Martina;
Colavita, Francesca;
Meschi, Silvia;
Maggi, Fabrizio;
Fimia, Gian Maria;
Fulci, Valerio

Publication type:

Article

Piclamilast inhibits the pro-apoptotic and anti-proliferative responses of A549 cells exposed to H2O2 via mechanisms involving AP-1 activation.

Published in:

Free Radical Research, 2012, v. 46, n. 5, p. 690, doi. 10.3109/10715762.2012.669040

By:

Mata, Manuel;
Pallardo, Federico;
Morcillo, Esteban Jesús;
Cortijo, Julio

Publication type:

Article

Photoprotective Effect of Taurine‐Rich Protamex Extract From Salmon (Oncorhynchus keta) Byproduct Against Ultraviolet B‐Induced Skin Damage in Human Dermal Fibroblasts and Zebrafish Model.

Published in:

Photodermatology, Photoimmunology & Photomedicine, 2025, v. 41, n. 1, p. 1, doi. 10.1111/phpp.13019

By:

Im, Seung Tae;
Kim, Wook Chul;
Lee, Seung‐Hong

Publication type:

Article

Design of an Herbal Preparation Composed by a Combination of Ruscus aculeatus L. and Vitis vinifera L. Extracts, Magnolol and Diosmetin to Address Chronic Venous Diseases through an Anti-Inflammatory Effect and AP-1 Modulation.

Published in:

Plants (2223-7747), 2023, v. 12, n. 5, p. 1051, doi. 10.3390/plants12051051

By:

Nocera, Raffaella;
Eletto, Daniela;
Santoro, Valentina;
Parisi, Valentina;
Bellone, Maria Laura;
Izzo, Marcello;
Tosco, Alessandra;
Dal Piaz, Fabrizio;
Donadio, Giuliana;
De Tommasi, Nunziatina

Publication type:

Article

T-5224, a selective inhibitor of c-Fos/activator protein-1, improves survival by inhibiting serum high mobility group box-1 in lethal lipopolysaccharide-induced acute kidney injury model.

Published in:

Journal of Intensive Care, 2015, v. 3, p. 1, doi. 10.1186/s40560-015-0115-2

By:

Mari Ishida;
Nobuhiro Maekawa;
Masaaki Ueki;
Jun Morishita;
Masaki Ueno;
Shunichi Shiozawa

Publication type:

Article

PI(3,4,5)P3 allosteric regulation of repressor activator protein 1 controls antigenic variation in trypanosomes.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.89331

By:

Touray, Abdoulie O.;
Rajesh, Rishi;
Isebe, Tony;
Sternlieb, Tamara;
Loock, Mira;
Kutova, Oksana;
Cestari, Igor

Publication type:

Article

Temporally specific gene expression and chromatin remodeling programs regulate a conserved Pdyn enhancer.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.89993

By:

Phillips, Robert A.;
Wan, Ethan;
Tuscher, Jennifer J.;
Reid, David;
Drake, Olivia R.;
Ianov, Lara;
Day, Jeremy J.

Publication type:

Article

KDM2B regulates inflammation and oxidative stress of sepsis via targeting NF‐κB and AP‐1 pathways.

Published in:

Immunity, Inflammation & Disease, 2023, v. 11, n. 9, p. 1, doi. 10.1002/iid3.985

By:

Li, Xin;
Tian, Xinyu;
Zhang, Dongliang

Publication type:

Article

Programmed gene expression change in mouse skin after ultraviolet radiation damage.

Published in:

Experimental Dermatology, 2022, v. 31, n. 6, p. 862, doi. 10.1111/exd.14519

By:

Yang, Kaibin;
Song, Shiting;
Zhang, Yafei;
Shen, Siting;
Xu, Xingzhi;
Yue, Zhicao

Publication type:

Article

Potential treatment of keloid pathogenesis with follistatin 288 by blocking the activin molecular pathway.

Published in:

Experimental Dermatology, 2021, v. 30, n. 3, p. 402, doi. 10.1111/exd.14223

By:

Ham, Seungmin;
Harrison, Craig;
de Kretser, David;
Wallace, Euan M.;
Southwick, Graeme;
Temple‐Smith, Peter

Publication type:

Article

Dectin-1 ligands produce distinct training phenotypes in human monocytes through differential activation of signaling networks.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-51620-8

By:

Cheng, Quen J.;
Farrell, Kylie;
Fenn, Jeffrey;
Ma, Zuchao;
Makanani, Sara K.;
Siemsen, Jonathan

Publication type:

Article

Dectin-1 ligands produce distinct training phenotypes in human monocytes through differential activation of signaling networks.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-51620-8

By:

Cheng, Quen J.;
Farrell, Kylie;
Fenn, Jeffrey;
Ma, Zuchao;
Makanani, Sara K.;
Siemsen, Jonathan

Publication type:

Article

Preliminary exploration of the role of FOS immunohistochemistry in proliferative fasciitis and myositis.

Published in:

Histopathology, 2022, v. 81, n. 3, p. 414, doi. 10.1111/his.14716

By:

Vargas, Ana C;
Ma, Leanne;
Talbot, Joel;
Gill, Anthony J;
Maclean, Fiona M

Publication type:

Article

A Novel lncRNA Regulates the Toll-Like Receptor Signaling Pathway and Related Immune Function by Stabilizing FOS mRNA as a Competitive Endogenous RNA.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00838

By:

Fan, Hao;
Lv, Zengpeng;
Gan, Liping;
Ning, Chao;
Li, Zhui;
Yang, Minghui;
Zhang, Beibei;
Song, Bochen;
Li, Guang;
Tang, Dazhi;
Gao, Jinxin;
Yan, Shaojia;
Wang, Youli;
Liu, Jianfeng;
Guo, Yuming

Publication type:

Article

Holding All the CARDs: How MALT1 Controls CARMA/CARD-Dependent Signaling.

Published in:

Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.01927

By:

Juilland, Mélanie;
Thome, Margot

Publication type:

Article

ANKRD1 is a mesenchymal-specific driver of cancer-associated fibroblast activation bridging androgen receptor loss to AP-1 activation.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45308-w

By:

Mazzeo, Luigi;
Ghosh, Soumitra;
Di Cicco, Emery;
Isma, Jovan;
Tavernari, Daniele;
Samarkina, Anastasia;
Ostano, Paola;
Youssef, Markus K.;
Simon, Christian;
Dotto, G. Paolo

Publication type:

Article

Age-related self-DNA accumulation may accelerate arthritis in rats and in human rheumatoid arthritis.

Published in:

Nature Communications, 2023, n. 1, p. 1, doi. 10.1038/s41467-023-40113-3

By:

Luo, Wei-Dan;
Wang, Yu-Ping;
Lv, Jun;
Liu, Yong;
Qu, Yuan-Qing;
Xu, Xiong-Fei;
Yang, Li-Jun;
Lin, Zi-Cong;
Wang, Lin-Na;
Chen, Rui-Hong;
Yang, Jiu-Jie;
Zeng, Ya-Ling;
Zhang, Rui-Long;
Huang, Bai-Xiong;
Yun, Xiao-Yun;
Wang, Xuan-Ying;
Song, Lin-Lin;
Wu, Jian-Hui;
Wang, Xing-Xia;
Chen, Xi

Publication type:

Article

Golgin-97 Targets Ectopically Expressed Inward Rectifying Potassium Channel, Kir2.1, to the trans-Golgi Network in COS-7 Cells.

Published in:

Frontiers in Physiology, 2018, p. 1, doi. 10.3389/fphys.2018.01070

By:

Taneja, Tarvinder K.;
Donghui Ma;
Kim, Bo Y.;
Welling, Paul A.

Publication type:

Article

ETV2/ER71 regulates the generation of FLK1+ cells from mouse embryonic stem cells through miR-126-MAPK signaling.

Published in:

Stem Cell Research & Therapy, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13287-019-1466-8

By:

Kim, Ju Young;
Lee, Dong Hun;
Kim, Joo Kyung;
Choi, Hong Seo;
Dwivedi, Bhakti;
Rupji, Manali;
Kowalski, Jeanne;
Green, Stefan J.;
Song, Heesang;
Park, Won Jong;
Chang, Ji Young;
Kim, Tae Min;
Park, Changwon

Publication type:

Article

Influence of o,p′-DDT on MUC5AC expression via regulation of NF-κB/AP-1 activation in human lung epithelial cells.

Published in:

Journal of Toxicology & Environmental Health: Part A, 2021, v. 84, n. 20, p. 836, doi. 10.1080/15287394.2021.1944943

By:

Lee, Gi Ho;
Jin, Sun Woo;
Choi, Jae Ho;
Han, Eun Hee;
Hwang, Yong Pil;
Choi, Chul Yung;
Jeong, Hye Gwang

Publication type:

Article

Retraction Note: Progesterone receptor assembly of a transcriptional complex along with activator protein 1, signal transducer and activator of transcription 3 and ErbB-2 governs breast cancer growth and predicts response to endocrine therapy.

Published in:

Breast Cancer Research, 2023, v. 25, n. 1, p. 1, doi. 10.1186/s13058-023-01735-z

By:

Flaqué, María C. Díaz;
Galigniana, Natalia M.;
Béguelin, Wendy;
Vicario, Rocío;
Proietti, Cecilia J.;
Russo, Rosalía Cordo;
Rivas, Martín A.;
Tkach, Mercedes;
Guzmán, Pablo;
Roa, Juan C.;
Maronna, Esteban;
Pineda, Viviana;
Muñoz, Sergio;
Mercogliano, María Florencia;
Charreau, Eduardo H.;
Yankilevich, Patricio;
Schillaci, Roxana;
Elizalde, Patricia V.

Publication type:

Article

Essential role of PLD2 in hypoxia-induced stemness and therapy resistance in ovarian tumors.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2024, v. 43, n. 1, p. 1, doi. 10.1186/s13046-024-02988-y

By:

Muñoz-Galván, Sandra;
Verdugo-Sivianes, Eva M.;
Santos-Pereira, José M.;
Estevez-García, Purificación;
Carnero, Amancio

Publication type:

Article

SOX4 exerts contrasting regulatory effects on labor-associated gene promoters in myometrial cells.

Published in:

PLoS ONE, 2024, v. 19, n. 4, p. 1, doi. 10.1371/journal.pone.0297847

By:

Khader, Nawrah;
Shchuka, Virlana M.;
Dorogin, Anna;
Shynlova, Oksana;
Mitchell, Jennifer A.

Publication type:

Article

Analysis of genes characterizing chronic thrombosis and associated pathways in chronic thromboembolic pulmonary hypertension.

Published in:

PLoS ONE, 2024, v. 19, n. 3, p. 1, doi. 10.1371/journal.pone.0299912

By:

Zhan, Shizhang;
Wang, Liu;
Wang, Wenping;
Li, Ruoran

Publication type:

Article

Upregulation of human GD3 synthase (hST8Sia I) gene expression during serum starvation-induced osteoblastic differentiation of MG-63 cells.

Published in:

PLoS ONE, 2023, v. 18, n. 11, p. 1, doi. 10.1371/journal.pone.0293321

By:

An, So-Young;
Yoon, Hyun-Kyoung;
Kim, Kyoung-Sook;
Kim, Hee-Do;
Cho, Jong-Hyun;
Kim, Hyeon-Jun;
Kim, Cheorl-Ho;
Lee, Young-Choon

Publication type:

Article

Heterogeneity in quiescent Müller glia in the uninjured zebrafish retina drive differential responses following photoreceptor ablation.

Published in:

Frontiers in Molecular Neuroscience, 2023, p. 1, doi. 10.3389/fnmol.2023.1087136

By:

Krylov, Aaron;
Shuguang Yu;
Veen, Kellie;
Newton, Axel;
Aojun Ye;
Huiwen Qin;
Jie He;
Jusuf, Patricia R.

Publication type:

Article

NOX4, a new genetic target for anti‐cancer therapy in digestive system cancer.

Published in:

Journal of Digestive Diseases, 2018, v. 19, n. 10, p. 578, doi. 10.1111/1751-2980.12651

By:

Tang, Chao Tao;
Gao, Yun Jie;
Ge, Zhi Zheng

Publication type:

Article

Genome-wide identification of enhancers and transcription factors regulating the myogenic differentiation of bovine satellite cells.

Published in:

BMC Genomics, 2021, v. 22, n. 1, p. 1, doi. 10.1186/s12864-021-08224-7

By:

Lyu, Pengcheng;
Settlage, Robert E.;
Jiang, Honglin

Publication type:

Article

The chromatin remodeling protein ATRX positively regulates IRF3-dependent type I interferon production and interferon-induced gene expression.

Published in:

PLoS Pathogens, 2022, v. 18, n. 8, p. 1, doi. 10.1371/journal.ppat.1010748

By:

Stilp, Anne-Charlotte;
Scherer, Myriam;
König, Patrick;
Fürstberger, Axel;
Kestler, Hans A.;
Stamminger, Thomas

Publication type:

Article

The paracaspase MALT1 in psoriasis.

Published in:

Biological Chemistry, 2021, v. 402, n. 12, p. 1583, doi. 10.1515/hsz-2021-0250

By:

Hailfinger, Stephan;
Schulze-Osthoff, Klaus

Publication type:

Article

The pregnant myometrium is epigenetically activated at contractility-driving gene loci prior to the onset of labor in mice.

Published in:

PLoS Biology, 2020, v. 18, n. 7, p. 1, doi. 10.1371/journal.pbio.3000710

By:

Shchuka, Virlana M.;
Abatti, Luis E.;
Hou, Huayun;
Khader, Nawrah;
Dorogin, Anna;
Wilson, Michael D.;
Shynlova, Oksana;
Mitchell, Jennifer A.

Publication type:

Article

Effects of Kudoa septempunctata infections in a human intestinal epithelial model (Caco-2): a DNA microarray study.

Published in:

Bioscience, Biotechnology & Biochemistry, 2020, v. 84, n. 5, p. 1030, doi. 10.1080/09168451.2019.1709791

By:

Yamamoto, So;
Kawano, Fumi;
Yokoyama, Hiroshi;
Kobayashi, Shoko

Publication type:

Article

Ethanol Extract of Rosa laevigata Michx. Fruit Inhibits Inflammatory Responses through NF-κB/MAPK Signaling Pathways via AMPK Activation in RAW 264.7 Macrophages.

Published in:

Molecules, 2023, v. 28, n. 6, p. 2813, doi. 10.3390/molecules28062813

By:

Wu, Hongtan;
Lin, Tingting;
Chen, Yupei;
Chen, Fangfang;
Zhang, Shudi;
Pang, Haiyue;
Huang, Lisen;
Yu, Chihli;
Wang, Gueyhorng;
Wu, Chun

Publication type:

Article

Effects of Epigallocatechin-3-Gallate on Matrix Metalloproteinases in Terms of Its Anticancer Activity.

Published in:

Molecules, 2023, v. 28, n. 2, p. 525, doi. 10.3390/molecules28020525

By:

Tanabe, Hiroki;
Suzuki, Takuji;
Ohishi, Tomokazu;
Isemura, Mamoru;
Nakamura, Yoriyuki;
Unno, Keiko

Publication type:

Article

Hesperidin Exhibits Protective Effects against PM 2.5 -Mediated Mitochondrial Damage, Cell Cycle Arrest, and Cellular Senescence in Human HaCaT Keratinocytes.

Published in:

Molecules, 2022, v. 27, n. 15, p. 4800, doi. 10.3390/molecules27154800

By:

Herath, Herath Mudiyanselage Udari Lakmini;
Piao, Mei Jing;
Kang, Kyoung Ah;
Zhen, Ao Xuan;
Fernando, Pincha Devage Sameera Madushan;
Kang, Hee Kyoung;
Yi, Joo Mi;
Hyun, Jin Won

Publication type:

Article

TAK1/AP-1-Targeted Anti-Inflammatory Effects of Barringtonia augusta Methanol Extract.

Published in:

Molecules, 2021, v. 26, n. 10, p. 3053, doi. 10.3390/molecules26103053

By:

Ha, Anh Thu;
Kim, Mi-Yeon;
Cho, Jae Youl;
Lui, Edmund M.K.

Publication type:

Article

Effect of Korean Red Ginseng and Rg3 on Asian Sand Dust-Induced MUC5AC, MUC5B, and MUC8 Expression in Bronchial Epithelial Cells.

Published in:

Molecules, 2021, v. 26, n. 7, p. 2002, doi. 10.3390/molecules26072002

By:

Shin, Seung-Heon;
Ye, Mi-Kyung;
Lee, Dong-Won;
Kang, Byung-Jun;
Chae, Mi-Hyun;
Pak, Sokcheon;
Ooi, Soo Liang;
Cuadrado, Carmen

Publication type:

Article

Acer tataricum subsp. ginnala Inhibits Skin Photoaging via Regulating MAPK/AP-1, NF-κB, and TGFβ/Smad Signaling in UVB-Irradiated Human Dermal Fibroblasts.

Published in:

Molecules, 2021, v. 26, n. 3, p. 662, doi. 10.3390/molecules26030662

By:

Jin, Yu-Jung;
Ji, Yura;
Jang, Young-Pyo;
Choung, Se-Young;
Majtan, Juraj

Publication type:

Article

Anti-Inflammatory Activity and Mechanism of Isookanin, Isolated by Bioassay-Guided Fractionation from Bidens pilosa L.

Published in:

Molecules, 2021, v. 26, n. 2, p. 255, doi. 10.3390/molecules26020255

By:

Xin, Ying-Ji;
Choi, Soojung;
Roh, Kyung-Baeg;
Cho, Eunae;
Ji, Hyanggi;
Weon, Jin Bae;
Park, Deokhoon;
Whang, Wan Kyunn;
Jung, Eunsun;
McPhee, Derek

Publication type:

Article

Euodia pasteuriana Methanol Extract Exerts Anti-Inflammatory Effects by Targeting TAK1 in the AP-1 Signaling Pathway.

Published in:

Molecules, 2020, v. 25, n. 23, p. 5760, doi. 10.3390/molecules25235760

By:

Zhang, Jianmei;
Kim, Mi-Yeon;
Cho, Jae Youl;
Lui, Edmund M.K.

Publication type:

Article

Protective Effect of Diphlorethohydroxycarmalol Isolated from Ishige okamurae Against Particulate Matter-Induced Skin Damage by Regulation of NF-κB, AP-1, and MAPKs Signaling Pathways In Vitro in Human Dermal Fibroblasts.

Published in:

Molecules, 2020, v. 25, n. 5, p. 1055, doi. 10.3390/molecules25051055

By:

Wang, Lei;
Kim, Hyun Soo;
Je, Jun-Geon;
Oh, Jae Young;
Kim, Young-Sang;
Cha, Seon-Heui;
Jeon, You-Jin

Publication type:

Article

The phenyl-thiophenyl propenone RK-I-123 reduces the levels of reactive oxygen species and suppresses the activation of NF-κB and AP-1 and IL-8 expression in Helicobacter pylori-infected gastric epithelial AGS cells.

Published in:

Inflammation Research, 2013, v. 62, n. 7, p. 689, doi. 10.1007/s00011-013-0621-4

By:

Jang, Sung;
Cho, Soonok;
Lee, Eung-Seok;
Kim, Jung;
Kim, Hyeyoung

Publication type:

Article

Tumour necrosis factor-alpha in uraemic serum promotes osteoblastic transition and calcification of vascular smooth muscle cells via extracellular signal-regulated kinases and activator protein 1/c-FOS-mediated induction of interleukin 6 expression.

Published in:

Nephrology Dialysis Transplantation, 2018, v. 33, n. 4, p. 574, doi. 10.1093/ndt/gfx316

By:

Zickler, Daniel;
Luecht, Christian;
Willy, Kevin;
Chen, Lei;
Witowski, Janusz;
Girndt, Matthias;
Fiedler, Roman;
Storr, Markus;
Kamhieh-Milz, Julian;
Schoon, Janosch;
Geissler, Sven;
Ringdén, Olle;
Schindler, Ralf;
Moll, Guido;
Dragun, Duska;
Catar, Rusan

Publication type:

Article

Plasmalogens Extracted from Ascidian Induce Neurite Outgrowth via Stimulation of CRE-, SRE-, and API-Mediated Transcription in PC12 Cells and Improve MK-801-Induced Memory Impairment in Mice.

Published in:

Pharmacometrics / Ōyō Yakuri (0300-8533), 2022, v. 102, n. 5/6, p. 97

By:

Akira Nakajima;
Maki Kamada;
Michi Kawada;
Sho Sakai;
Masaki Okawara;
Masahiro Kurono;
Yoshiharu Matahira;
Yasushi Ohizumi

Publication type:

Article

Anti-Inflammatory Therapeutic Mechanisms of Isothiocyanates: Insights from Sulforaphane.

Published in:

Biomedicines, 2024, v. 12, n. 6, p. 1169, doi. 10.3390/biomedicines12061169

By:

Habtemariam, Solomon

Publication type:

Article

The association between oxidative stress, activator protein-1, inflammatory, total antioxidant status and artery stiffness and the efficacy of olmesartan in elderly patients with mild-to-moderate essential hypertension.

Published in:

Clinical & Experimental Hypertension, 2016, v. 38, n. 4, p. 365, doi. 10.3109/10641963.2015.1131285

By:

Liu, Qunwei;
Han, Limin;
Du, Qiufan;
Zhang, Ming;
Zhou, Shenghua;
Shen, Xiangqian

Publication type:

Article