Works matching DE "LIGANDS (Biochemistry)"

Results: 5000

Tandem CAR T-cells targeting CD19 and NKG2DL can overcome CD19 antigen escape in B-ALL.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1557405

By:

Bolsée, Jennifer;
Violle, Benjamin;
Jacques-Hespel, Céline;
Nguyen, Thuy;
Lonez, Caroline;
Breman, Eytan

Publication type:

Article

Evaluating AutoGrow4 – an open-source toolkit for semi-automated computer-aided drug discovery.

Published in:

Expert Opinion on Drug Discovery, 2025, v. 20, n. 6, p. 711, doi. 10.1080/17460441.2025.2499122

By:

Bassani, Davide;
Pavan, Matteo;
Moro, Stefano

Publication type:

Article

Data‐Driven Prediction of Reactivity and Additive Selection for C(sp<sup>2</sup>)–(Hetero)Atom Bond Couplings in an Adaptive Dynamic Homogeneous Catalysis.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 29, p. 1, doi. 10.1002/chem.202500935

By:

Fan, Li‐Yang;
Li, Xue‐Tao;
Luo, Xi‐Xi;
Zhu, Bo;
Guan, Wei

Publication type:

Article

Evidence of focusing the MHC class I immunopeptidome by tapasin.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1563789

By:

Darley, Rachel;
Illing, Patricia T.;
Duriez, Patrick;
Bailey, Alistair;
Purcell, Anthony W.;
van Hateren, Andy;
Elliott, Tim

Publication type:

Article

In-silico molecular investigation of Nannochloropsis microalgae cellulose synthase under salinity conditions and in-vitro evaluation of the proportionate effects on cellulose production.

Published in:

3 Biotech, 2025, v. 15, n. 6, p. 1, doi. 10.1007/s13205-025-04329-y

By:

Haghayeghi, Seyed Mohammad Hasan;
Azimzadeh Irani, Maryam;
Askari, Hossein;
Rasa, Madihe Sadat;
Shariatmadari, Zeinab

Publication type:

Article

Understanding the Structure of Protonated Box Ligands: Insights from Spectroscopy and Computational Studies.

Published in:

Helvetica Chimica Acta, 2025, v. 108, n. 5, p. 1, doi. 10.1002/hlca.202400205

By:

Gorbachev, Vladimir;
van Tetering, Lara;
Martens, Jonathan;
Oomens, Jos;
Berden, Giel;
Tsybizova, Alexandra;
Chen, Peter

Publication type:

Article

Selection and Characterization of a DNA Aptamer Recognizing High Mobility Group Box 1 Protein (HMGB1) and Enhancing Its Pro-inflammatory Activity.

Published in:

IJ Pharmaceutical Research (IJPR), 2024, v. 23, n. 1, p. 1, doi. 10.5812/ijpr-147246

By:

Li, Hanchao;
Sun, Wengang;
Huang, Yanhua;
Li, Qian;
Tian, Hong;
Hao, Zhiming;
Huo, Yongwei

Publication type:

Article

SYNTHESIS, SPECTROSCOPIC STUDIES AND EVALUATION OF BIOLOGICAL ACTIVITY OF SOME SUBSISTUDED 1,2,4-TRIAZOLES AND THEIR COMPLEXES WITH Co(II), Ni(II) AND Zn(II) IONS.

Published in:

Bulletin of the Chemical Society of Ethiopia, 2025, v. 39, n. 6, p. 1119, doi. 10.4314/bcse.v39i6.8

By:

Mohammed, Intisar A.;
Al-Assafe, Amaal Y.;
Fathi, Anwar A.

Publication type:

Article

Mit KI vom Molekül zum Therapeutikum.

Published in:

Kompass Ophthalmologie, 2025, v. 11, n. 2, p. 54, doi. 10.1159/000545950

By:

Strauß, Olaf

Publication type:

Article

Harnessing Spirulina Extract to Enhance Drought Tolerance in Wheat: A Morphological, Molecular Genetic and Molecular Docking Approach.

Published in:

Egyptian Academic Journal of Biological Sciences, H. Botany, 2024, v. 15, n. 2, p. 73, doi. 10.21608/EAJBSH.2024.397935

By:

Ibrahim, Mona I. M.;
Ahmed, Alshimaa T.;
El-Dougdoug, Khaled A.;
El Nady, Ghada H.

Publication type:

Article

"Revolutionizing Cancer Treatment: The Role of Starch‐Based Nanoparticles in Targeted Therapy".

Published in:

Starch / Staerke, 2025, v. 77, n. 5, p. 1, doi. 10.1002/star.202400251

By:

Kapoor, Devesh U.;
Patel, Geeta;
Prajapati, Bhupendra G.

Publication type:

Article

In silico analysis to explore the therapeutic potential of propolis-derived small molecules as matriptase inhibitors to suppress breast cancer growth and metastasis.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0321687

By:

Azmi, Muhammad Bilal;
Yu, Han;
Sohail, Arisha;
Asif, Uzma;
Ahmed, Syed Danish Haseen;
Qureshi, Shamim Akhtar;
Abdalla, Mohnad

Publication type:

Article

The endocannabinoid system in cancer biology: a mini-review of mechanisms and therapeutic potential.

Published in:

Oncology Reviews, 2025, p. 1, doi. 10.3389/or.2025.1573797

By:

Salum, Kaio Cezar Rodrigues;
Miranda, Gabriel Brendo Alves;
Dias, Alessandra Lima;
Carneiro, João Regis Ivar;
Bozza, Patrícia Torres;
da Fonseca, Ana Carolina Proença;
Silva, Tamara

Publication type:

Article

New Cu(II), Cu(I) and Ag(I) Complexes of Phenoxy-Ketimine Schiff Base Ligands: Synthesis, Structures and Antibacterial Activity.

Published in:

Molecules, 2025, v. 30, n. 9, p. 1893, doi. 10.3390/molecules30091893

By:

Caviglia, Miriam;
Li, Zhenzhen;
Santini, Carlo;
Del Gobbo, Jo';
Cimarelli, Cristina;
Du, Miao;
Dolmella, Alessandro;
Pellei, Maura

Publication type:

Article

Influence of Nucleic Acids on Spectral Properties of Solutions of Pd(II) and Pt(II) Complexes with Aromatic Ligands.

Published in:

High Energy Chemistry, 2025, v. 59, n. 2, p. 173, doi. 10.1134/S0018143924701753

By:

Demidov, E. V.;
Abramova-Nemesh, M. V.;
Novikova, T. A.;
Plekhanov, A. Y.;
Feoktistova, V. A.;
Puzyk, M. V.

Publication type:

Article

Research Progress of GPR137 in Malignant Tumors: A Review.

Published in:

OncoTargets & Therapy, 2025, v. 18, p. 545, doi. 10.2147/OTT.S511943

By:

Li, Yangyang;
Yi, ZhongQuan;
Li, Xia;
Wang, Rui;
Zhao, Mengjie;
Mi, Lida;
Zhang, Weisong;
Guo, Rongqi;
Yan, Song;
Song, JianXiang

Publication type:

Article

E-cadherin mechanotransduction activates EGFR-ERK signaling in epithelial monolayers by inducing ADAM-mediated ligand shedding.

Published in:

Science Signaling, 2025, v. 18, n. 886, p. 1, doi. 10.1126/scisignal.adr7926

By:

Houtekamer, Ronja M.;
van der Net, Mirjam C.;
Vliem, Marjolein J.;
Noordzij, Tomas E. J. C.;
van Uden, Lisa;
van Es, Robert M.;
Sim, Joo Yong;
Deguchi, Eriko;
Terai, Kenta;
Hopcroft, Matthew A.;
Vos, Harmjan R.;
Pruitt, Beth L.;
Matsuda, Michiyuki;
Pannekoek, Willem-Jan;
Gloerich, Martijn

Publication type:

Article

A Positive Feedback DNA-PK/MYT1L-CXCR1-ERK1/2 Proliferative Signaling Loop in Glioblastoma.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 9, p. 4398, doi. 10.3390/ijms26094398

By:

Wang, Bo;
Li, Dongping;
Ilnytskyy, Yaroslav;
Khachigian, Levon M.;
Zhong, Nuanying;
Rodriguez-Juarez, Rocio;
Kovalchuk, Igor;
Kovalchuk, Olga

Publication type:

Article

GPR75: Advances, Challenges in Deorphanization, and Potential as a Novel Drug Target for Disease Treatment.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 9, p. 4084, doi. 10.3390/ijms26094084

By:

Han, Jingyi;
Li, Jiaojiao;
Yao, Sirui;
Wei, Zao;
Jiang, Hui;
Xu, Tao;
Zeng, Junwei;
Xu, Lin;
Han, Yong

Publication type:

Article

A Single-Domain VNAR Nanobody Binds with High-Affinity and Selectivity to the Heparin Pentasaccharide Fondaparinux.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 9, p. 4045, doi. 10.3390/ijms26094045

By:

Gschwandtner, Martha;
Derler, Rupert;
Talker, Elisa;
Trojacher, Christina;
Gubensäk, Nina;
Becker, Walter;
Gerlza, Tanja;
Klaus, Zangger;
Stocki, Pawel;
Walsh, Frank S.;
Rutkowski, Julia Lynn;
Kungl, Andreas

Publication type:

Article

Inside Front Cover: Enantioselective Synthesis of Chiral Ferrocenyl Aminoalcohols: Simultaneous Induction of Multiple Types of Chirality by a Rhodium‐Catalyzed Asymmetric Ring‐Opening Strategy (Angew. Chem. 20/2025).

Published in:

Angewandte Chemie, 2025, v. 137, n. 20, p. 1, doi. 10.1002/ange.202505856

By:

Isoda, Takamu;
Jimba, Komei;
Kawashima, Kyohei;
Nishinoiri, Takahiro;
Mori, Seiji;
Tsurusaki, Akihiro;
Kamikawa, Ken

Publication type:

Article

Profiling Allosteric Modulators of CB<sub>1</sub>R with an Allosteric Fluoroprobe.

Published in:

Angewandte Chemie, 2025, v. 137, n. 20, p. 1, doi. 10.1002/ange.202421885

By:

Kosar, Miroslav;
Perera, Themiya;
Ganzoni, Rudolf L. Z.;
Sarott, Roman C.;
Borrega‐Roman, Leire;
Vitale, Rosa Maria;
Ligresti, Alessia;
Rufer, Arne C.;
Guba, Wolfgang;
Grether, Uwe;
Carreira, Erick M.;
Veprintsev, Dmitry B.;
Sykes, David A.

Publication type:

Article

Paricalcitol promotes the maturation of immune granulomas in an experimental model of superoxide dismutase A-induced inflammation.

Published in:

Inflammation Research, 2025, v. 74, n. 1, p. 1, doi. 10.1007/s00011-025-02050-3

By:

ET, Ablyakimov;
MA, Kriventsov;
AV, Kubyshkin;
Kriventsov, Maxim A.

Publication type:

Article

Smad4 and TGFβ1 dependent gene expression signatures in conditional intestinal adenoma, organoids and colorectal cancer.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-00908-4

By:

Surakhy, Mirvat;
Matheson, Julia;
Barnes, David J.;
Carter, Emma J.;
Hughes, Jennifer;
Bühnemann, Claudia;
Sanegre, Sabina;
Morreau, Hans;
Metz, Paul;
Imianowski, Charlotte J.;
Hassan, Andrew Bassim

Publication type:

Article

Molecular characterization and immune role of TLR7 in Labeo rohita.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1555048

By:

Pani, Saswati;
Ganguly, Bristy;
Mahapatra, Smruti;
Dash, Smruti Prajnya;
Das, Rakesh;
Saha, Ashis;
Samanta, Mrinal

Publication type:

Article

Histocompatibility in Botryllus schlosseri and the origins of adaptive immunity.

Published in:

Immunogenetics, 2025, v. 77, n. 1, p. 1, doi. 10.1007/s00251-025-01379-7

By:

De Tomaso, Anthony W.;
Rodriguez-Valbuena, Henry

Publication type:

Article

Beyond fluorodeoxyglucose: Molecular imaging of cancer in precision medicine.

Published in:

CA: A Cancer Journal for Clinicians, 2025, v. 75, n. 3, p. 226, doi. 10.3322/caac.70007

By:

Juweid, Malik E.;
Al‐Qasem, Soud F.;
Khuri, Fadlo R.;
Gallamini, Andrea;
Lohmann, Philipp;
Ziellenbach, Hans‐Joachim;
Mottaghy, Felix M.

Publication type:

Article

Molecular Dynamics Study of Thymoquinone and Madecassoside as Potential Anti-Parkinson's Agents via Dopamine D2 Receptor Modulation.

Published in:

Tropical Journal of Natural Product Research, 2025, v. 9, n. 4, p. 1625, doi. 10.26538/tjnpr/v9i4.35

By:

Kusumawati, Shinta;
Endharti, Agustina T.;
Balafif, Farhad;
Kurniawan, Shahdevi N.;
Anaqah, Rabjhany;
Khotimah, Husnul

Publication type:

Article

SAPrIm 2.0: a semi-automated protocol for mid-throughput soluble HLA immunopeptidomics.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1546629

By:

Tanuwidjaya, Erwin;
Lim Kam Sian, Terry C. C.;
Steele, Joel R.;
Goncalves, Gabriel;
Woodhouse, Isaac B.;
Chang, Janet;
Ooi, Joshua D.;
Schittenhelm, Ralf B.;
Faridi, Pouya

Publication type:

Article

Lipooligosaccharide Ligands from Respiratory Bacterial Pathogens Enhance Cellular Uptake of Nanoparticles.

Published in:

KONA: Powder & Particle Journal, 2024, v. 41, p. 265, doi. 10.14356/kona.2024005

By:

Tu, Mai H.;
Brenza, Timothy M.;
Ketterer, Margaret R.;
Timm, Morgan;
King, Benjamin M.;
Apicella, Michael A.;
Fiegel, Jennifer

Publication type:

Article

Opioid Analgesics: Rise and Fall of Ligand Biased Signaling and Future Perspectives in the Quest for the Holy Grail.

Published in:

CNS Drugs, 2025, v. 39, n. 6, p. 565, doi. 10.1007/s40263-025-01172-w

By:

Breault, Émile;
Brouillette, Rebecca L.;
Hébert, Terence E.;
Sarret, Philippe;
Besserer-Offroy, Élie

Publication type:

Article

TAS2R Taste Receptor Clustering Suggests that Bitter Wine Taste Perception Forms a 2D Dataspace.

Published in:

Journal of Computational Biophysics & Chemistry, 2025, v. 24, n. 6, p. 795, doi. 10.1142/S2737416524500844

By:

Shityakov, Sergey;
Skorb, Ekaterina V.;
Nosonovsky, Michael

Publication type:

Article

Screening the Pandemic Response Box identifies novel ligands of the Staphylococcus aureus protein arginine kinase, McsB.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10545-9

By:

Chetty, Ryan;
Delport, Alexandré;
Mthembu, Sandile;
Veale, Clinton G. L.;
Hewer, Raymond

Publication type:

Article

New 3-acyl derivatives of glaucocalyxin A: designed, synthesis and in vitro antibacterial activities.

Published in:

Journal of Asian Natural Products Research, 2025, v. 27, n. 5, p. 677, doi. 10.1080/10286020.2024.2429136

By:

Yang, Wei-Xian;
Zhang, Wei-Qing;
Wei, Mei-Qi;
Duan, Mei-Hui;
Liu, Xian-Ji;
Yan, Chen

Publication type:

Article

The Toll like Receptors Signaling Modulated by Exosomal Mirna is linked with Induction of Autophagy for Protecting Auditory System: Novel Therapeutic Target for Inner Ear Disease.

Published in:

International Tinnitus Journal, 2025, v. 29, n. 1, p. 33, doi. 10.5935/0946-5448.2025006

By:

Ken Hayashi;
Hideaki Sakata

Publication type:

Article

Elucidation of short linear motif-based interactions of the MIT and rhodanese domains of the ubiquitin-specific protease 8.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00638-7

By:

Konstantinou, Aimiliani;
Varga, Julia K.;
Córdova-Pérez, Alicia;
Simonetti, Leandro;
Gomez-Lucas, Lidia;
Schueler-Furman, Ora;
Davey, Norman E.;
Kulathu, Yogesh;
Ivarsson, Ylva

Publication type:

Article

DockEM: an enhanced method for atomic-scale protein–ligand docking refinement leveraging low-to-medium resolution cryo-EM density maps.

Published in:

Briefings in Bioinformatics, 2025, v. 26, n. 2, p. 1, doi. 10.1093/bib/bbaf091

By:

Zou, Jing;
Zhang, Wenyi;
Hu, Jun;
Zhou, Xiaogen;
Zhang, Biao

Publication type:

Article

Learning directed acyclic graphs for ligands and receptors based on spatially resolved transcriptomic data of ovarian cancer.

Published in:

Briefings in Bioinformatics, 2025, v. 26, n. 2, p. 1, doi. 10.1093/bib/bbaf085

By:

Chowdhury, Shrabanti;
Ferri-Borgogno, Sammy;
Yang, Peng;
Wang, Wenyi;
Peng, Jie;
Mok, Samuel C;
Wang, Pei

Publication type:

Article

Cannabis: A Balanced Mini-Review.

Published in:: Nutritional Perspectives: Journal of the Council on Nutrition, 2020, v. 43, n. 2, p. 22
Publication type:: Article

The imidazoline receptors and ligands in pain modulation.

Published in:

Indian Journal of Pharmacology, 2015, v. 47, n. 5, p. 472, doi. 10.4103/0253-7613.165196

By:

Bektas, Nurcan;
Nemutlu, Dilara;
Arslan, Rana

Publication type:

Article

The role of peroxisome proliferator-activated receptors in human disease.

Published in:

Indian Journal of Pharmacology, 2006, v. 38, n. 4, p. 243

By:

Javiya, V.A.;
Patel, J.A.

Publication type:

Article

Skin Surface Protein Detection by Transdermal Analysis Patches in Pediatric Psoriasis.

Published in:

Skin Pharmacology & Physiology, 2021, v. 34, n. 5, p. 271, doi. 10.1159/000516110

By:

Schaap, Mirjam J.;
Bruins, Finola M.;
He, Xuehui;
Orro, Kadri;
Peppelman, Malou;
van Erp, Piet E. J.;
de Jong, Elke M. G. J.;
Koenen, Hans J. P. M.;
van den Bogaard, Ellen H.;
Seyger, Marieke M. B.

Publication type:

Article

Expression profile of Eph receptors and ephrin ligands in human skin and downregulation of EphA1 in nonmelanoma skin cancer.

Published in:

Modern Pathology, 2006, v. 19, n. 10, p. 1369, doi. 10.1038/modpathol.3800660

By:

Hafner, Christian;
Becker, Bernd;
Landthaler, Michael;
Vogt, Thomas

Publication type:

Article

Lack of c-kit (CD117) expression in CD30+ lymphomas and lymphomatoid papulosis.

Published in:

Modern Pathology, 2004, v. 17, n. 8, p. 946, doi. 10.1038/modpathol.3800144

By:

Rassidakis, George Z.;
Georgakis, Georgios V.;
Oyarzo, Mauricio;
Younes, Anas;
Medeiros, L. Jeffrey

Publication type:

Article

Tandem Domains with Tuned Interactions Are a Powerful Biological Design Principle.

Published in:

PLoS Biology, 2015, v. 13, n. 12, p. 1, doi. 10.1371/journal.pbio.1002306

By:

Nussinov, Ruth;
Tsai, Chung-Jung

Publication type:

Article

The Maternal Maverick/GDF15-like TGF-β Ligand Panda Directs Dorsal-Ventral Axis Formation by Restricting Nodal Expression in the Sea Urchin Embryo.

Published in:

PLoS Biology, 2015, v. 13, n. 9, p. 1, doi. 10.1371/journal.pbio.1002247

By:

Haillot, Emmanuel;
Molina, Maria Dolores;
Lapraz, François;
Lepage, Thierry

Publication type:

Article

Signature Patterns of MHC Diversity in Three Gombe Communities of Wild Chimpanzees Reflect Fitness in Reproduction and Immune Defense against SIVcpz.

Published in:

PLoS Biology, 2015, v. 13, n. 5, p. 1, doi. 10.1371/journal.pbio.1002144

By:

Wroblewski, Emily E.;
Norman, Paul J.;
Guethlein, Lisbeth A.;
Rudicell, Rebecca S.;
Ramirez, Miguel A.;
Li, Yingying;
Hahn, Beatrice H.;
Pusey, Anne E.;
Parham, Peter

Publication type:

Article

Site-Directed Spin Labeling Reveals Pentameric Ligand-Gated Ion Channel Gating Motions.

Published in:

PLoS Biology, 2013, v. 11, n. 11, p. 1, doi. 10.1371/journal.pbio.1001714

By:

Dellisanti, Cosma D.;
Ghosh, Borna;
Hanson, Susan M.;
Raspanti, James M.;
Grant, Valerie A.;
Diarra, Gaoussou M.;
Schuh, Abby M.;
Satyshur, Kenneth;
Klug, Candice S.;
Czajkowski, Cynthia

Publication type:

Article

Steroids as Central Regulators of Organismal Development and Lifespan.

Published in:

PLoS Biology, 2012, v. 10, n. 4, p. 1, doi. 10.1371/journal.pbio.1001307

By:

Lee, Siu Sylvia;
Schroeder, Frank C.

Publication type:

Article

Binding of Superantigen Toxins into the CD28 Homodimer Interface Is Essential for Induction of Cytokine Genes That Mediate Lethal Shock.

Published in:

PLoS Biology, 2011, v. 9, n. 9, p. 1, doi. 10.1371/journal.pbio.1001149

By:

Arad, Gila;
Levy, Revital;
Nasie, Iris;
Hillman, Dalia;
Rotfogel, Ziv;
Barash, Uri;
Supper, Emmanuelle;
Shpilka, Tomer;
Minis, Adi;
Kaempfer, Raymond

Publication type:

Article