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ATF6 is required for efficient rhodopsin clearance and retinal homeostasis in the P23H rho retinitis pigmentosa mouse model.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-95895-7
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- Publication type:
- Article
IRE1α prevents hepatic steatosis by processing and promoting the degradation of select microRNAs.
- Published in:
- Science Signaling, 2018, v. 11, n. 530, p. 1, doi. 10.1126/scisignal.aao4617
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- Publication type:
- Article
Interplay Between the Oxidoreductase PDIA6 and microRNA-322 Controls the Response to Disrupted Endoplasmic Reticulum Calcium Homeostasis.
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- Science Signaling, 2014, v. 7, n. 329, p. 1, doi. 10.1126/scisignal.2004983
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- Article
A common frameshift mutation in von Willebrand factor does not alter mRNA stability but interferes with normal propeptide processing.
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- British Journal of Haematology, 1996, v. 95, n. 1, p. 184, doi. 10.1046/j.1365-2141.1996.7572377.x
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- Article
Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia.
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- Nature Genetics, 2015, v. 47, n. 7, p. 757, doi. 10.1038/ng.3319
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- Publication type:
- Article
Bleeding due to disruption of a cargo-specific ER-to-Golgi transport complex.
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- Nature Genetics, 2003, v. 34, n. 2, p. 220, doi. 10.1038/ng1153
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- Publication type:
- Article
The ER Unfolded Protein Response Effector, ATF6, Reduces Cardiac Fibrosis and Decreases Activation of Cardiac Fibroblasts.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 4, p. 1373, doi. 10.3390/ijms21041373
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- Article
Concomitant Nrf2- and ATF4-Activation by Carnosic Acid Cooperatively Induces Expression of Cytoprotective Genes.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 7, p. 1706, doi. 10.3390/ijms20071706
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- Article
Cargo Selectivity of the ERGIC-53/MCFD2 Transport Receptor Complex.
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- Traffic, 2006, v. 7, n. 11, p. 1473, doi. 10.1111/j.1600-0854.2006.00483.x
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- Article
292-OR: Inflammatory Cytokines Rewire the Proinsulin Interaction Network in Human Islets.
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- Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-292-OR
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- Article
Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding.
- Published in:
- 2020
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- Publication type:
- journal article
47-OR: A Reference Map of the Human Proinsulin Biosynthetic Interaction Network.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-47-OR
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- Publication type:
- Article
Role of Proinsulin Self-Association in Mutant INS Gene–Induced Diabetes of Youth.
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- Diabetes, 2020, v. 69, n. 5, p. 954, doi. 10.2337/db19-1106
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- Article
Ameliorating Methylglyoxal-Induced Progenitor Cell Dysfunction for Tissue Repair in Diabetes.
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- 2019
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- Publication type:
- journal article
in Neurons Is Required for Thermogenesis and Glycemia.
- Published in:
- 2017
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- Publication type:
- journal article
Antioxidants Complement the Requirement for Protein Chaperone Function to Maintain β-Cell Function and Glucose Homeostasis.
- Published in:
- Diabetes, 2015, v. 64, n. 8, p. 2892, doi. 10.2337/db14-1357
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- Publication type:
- Article
Fine Tuning of the UPR by the Ubiquitin Ligases Siah1/2.
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- PLoS Genetics, 2014, v. 10, n. 5, p. 1, doi. 10.1371/journal.pgen.1004348
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- Article
Genetic Interactions Due to Constitutive and Inducible Gene Regulation Mediated by the Unfolded Protein Response in C. elegans.
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- PLoS Genetics, 2005, v. 1, n. 3, p. 355, doi. 10.1371/journal.pgen.0010037
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- Publication type:
- Article
The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of β Cells.
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- PLoS Biology, 2015, v. 13, n. 10, p. 1, doi. 10.1371/journal.pbio.1002277
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- Article
Molecular characterization and expression of the gene encoding human erythroid-potentiating activity.
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- Nature, 1985, v. 315, n. 6022, p. 768, doi. 10.1038/315768a0
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- Publication type:
- Article
Isolation and characterization of genomic and cDNA clones of human erythropoietin.
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- Nature, 1985, v. 313, n. 6005, p. 806, doi. 10.1038/313806a0
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- Publication type:
- Article
Correction of Murine Hemophilia A and Immunological Differences of Factor VIII Variants Delivered by Helper-dependent Adenoviral Vectors.
- Published in:
- Molecular Therapy, 2007, v. 15, n. 12, p. 2080, doi. 10.1038/sj.mt.6300308
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- Article
Naked DNA Transfer of Factor VIII Induced Transgene-Specific, Species-Independent Immune Response in Hemophilia A Mice
- Published in:
- Molecular Therapy, 2004, v. 10, n. 1, p. 117, doi. 10.1016/j.ymthe.2004.04.009
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- Publication type:
- Article
The impact of the unfolded protein response on human disease.
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- Journal of Cell Biology, 2012, v. 197, n. 7, p. 857, doi. 10.1083/jcb.201110131
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- Publication type:
- Article
The role of UDP-Glc:glycoprotein glucosyltransferase 1 in the maturation of an obligate substrate prosaposin.
- Published in:
- Journal of Cell Biology, 2010, v. 189, n. 5, p. 829, doi. 10.1083/jcb.200912105
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- Publication type:
- Article
Translational control of mGluR-dependent long-term depression and object-place learning by eIF2α.
- Published in:
- Nature Neuroscience, 2014, v. 17, n. 8, p. 1073, doi. 10.1038/nn.3754
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- Publication type:
- Article
A Crucial Role for RACK1 in the Regulation of Glucose-Stimulated IRE1α Activation in Pancreatic β Cells.
- Published in:
- Science Signaling, 2010, v. 3, n. 106, p. 1, doi. 10.1126/scisignal.2000514
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- Publication type:
- Article
Tumor Suppression by PTEN Requires the Activation of the PKR-elF2α Phosphorylation Pathway.
- Published in:
- Science Signaling, 2009, v. 2, n. 102, p. 1, doi. 10.1126/scisignal.2000389
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- Article
Functional analysis of the mammalian RNA ligase for IRE1 in the unfolded protein response.
- Published in:
- Bioscience Reports, 2017, v. 37, n. 2, p. 1, doi. 10.1042/BSR20160574
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- Publication type:
- Article
Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis.
- Published in:
- Nature Medicine, 2005, v. 11, n. 7, p. 757, doi. 10.1038/nm1259
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- Publication type:
- Article
eIF2α phosphorylation is required to prevent hepatocyte death and liver fibrosis in mice challenged with a high fructose diet.
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- Nutrition & Metabolism, 2017, v. 14, p. 1, doi. 10.1186/s12986-017-0202-6
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- Publication type:
- Article
ER stress and inflammation crosstalk in obesity.
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- Medicinal Research Reviews, 2023, v. 43, n. 1, p. 5, doi. 10.1002/med.21921
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- Publication type:
- Article
The impact of the endoplasmic reticulum protein-folding environment on cancer development.
- Published in:
- Nature Reviews Cancer, 2014, v. 14, n. 9, p. 581, doi. 10.1038/nrc3800
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- Article
The impact of the endoplasmic reticulum protein-folding environment on cancer development.
- Published in:
- 2014
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- Publication type:
- journal article
IRE1- and HAC1 -independent transcriptional regulation in the unfolded protein response of yeast.
- Published in:
- Molecular Microbiology, 2003, v. 49, n. 3, p. 591, doi. 10.1046/j.1365-2958.2003.03585.x
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- Publication type:
- Article
Transcription Factor ATF4 Induces NLRP1 Inflammasome Expression during Endoplasmic Reticulum Stress.
- Published in:
- PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0130635
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- Publication type:
- Article
Genetic Inhibition of Phosphorylation of the Translation Initiation Factor eIF2α Does Not Block Aβ-Dependent Elevation of BACE1 and APP Levels or Reduce Amyloid Pathology in a Mouse Model of Alzheimer’s Disease.
- Published in:
- PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0101643
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- Publication type:
- Article
Novel Bioinformatics Method for Identification of Genome-Wide Non-Canonical Spliced Regions Using RNA-Seq Data.
- Published in:
- PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0100864
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- Publication type:
- Article
Endoplasmic reticulum stress disrupts placental morphogenesis: implications for human intrauterine growth restriction.
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- Journal of Pathology, 2012, v. 228, n. 4, p. 554, doi. 10.1002/path.4068
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- Publication type:
- Article
Translation attenuation by PERK balances ER glycoprotein synthesis with lipid-linked oligosaccharide flux.
- Published in:
- Journal of Cell Biology, 2007, v. 176, n. 5, p. 605, doi. 10.1083/jcb.200607007
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- Publication type:
- Article
Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation.
- Published in:
- Journal of Cell Biology, 2006, v. 172, n. 3, p. 383, doi. 10.1083/jcb.200507057
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- Publication type:
- Article
Stress granules and processing bodies are dynamically linked sites of mRNP remodeling.
- Published in:
- Journal of Cell Biology, 2005, v. 169, n. 6, p. 871, doi. 10.1083/jcb.200502088
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- Publication type:
- Article
High-content screen for modifiers of Niemann-Pick type C disease in patient cells.
- Published in:
- Human Molecular Genetics, 2018, v. 27, n. 12, p. 2101, doi. 10.1093/hmg/ddy117
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- Publication type:
- Article
Inositol-requiring 1/X-box-binding protein 1 is a regulatory hub that links endoplasmic reticulum homeostasis with innate immunity and metabolism.
- Published in:
- EMBO Molecular Medicine, 2010, v. 2, n. 6, p. 189, doi. 10.1002/emmm.201000076
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- Publication type:
- Article
Proinsulin folding and trafficking defects trigger a common pathological disturbance of endoplasmic reticulum homeostasis.
- Published in:
- Protein Science: A Publication of the Protein Society, 2024, v. 33, n. 4, p. 1, doi. 10.1002/pro.4949
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- Publication type:
- Article
Read-Split-Run: an improved bioinformatics pipeline for identification of genome-wide non-canonical spliced regions using RNA-Seq data.
- Published in:
- BMC Genomics, 2016, v. 17, p. 107, doi. 10.1186/s12864-016-2896-7
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- Publication type:
- Article
Disulfiram (Antabuse) Activates ROS-Dependent ER Stress and Apoptosis in Oral Cavity Squamous Cell Carcinoma.
- Published in:
- Journal of Clinical Medicine, 2019, v. 8, n. 5, p. 611, doi. 10.3390/jcm8050611
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- Publication type:
- Article
Biosynthesis, structure, and folding of the insulin precursor protein.
- Published in:
- Diabetes, Obesity & Metabolism, 2018, v. 20, p. 28, doi. 10.1111/dom.13378
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- Publication type:
- Article
ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death.
- Published in:
- Nature Cell Biology, 2013, v. 15, n. 5, p. 481, doi. 10.1038/ncb2738
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- Publication type:
- Article
Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway.
- Published in:
- Nature Cell Biology, 2006, v. 8, n. 10, p. 1053, doi. 10.1038/ncb1471
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- Publication type:
- Article