Advances in immunological diagnosis research of human hydatid disease.

XIAO Ling; ZI Jin-rong; WU Fang-wei; LI Beng-fu; PENG Jia

Echinococcosis is a zoonotic parasitic disease caused by E. granulosus, E. multiloculari, E. shiquicus, E. orligarthrus and E.vogeli. Hydatid disease seriously endangers human health, brings great pain and heavy economic burden to the patients and their families, and is one of the main reasons for the poor people in the agricultural and pastoral areas in western China, and is a serious worldwide public health problem. Immunological diagnosis of hydatid disease plays an important role in clinical diagnosis, operation and prognosis evaluation and field epidemiological investigation. At present, the commonly used immunological detection methods for hydatidosis include ELISA, DIGFA, IHA, etc, with their own advantages and disadvantages, sensitivity, specificity and accuracy, and differences in experimental conditions, operation simplicity, time, field flow regulation, clinical application and information provided by test results. Due to the lack of standardization of the commonly used immunological detection methods, and the influence of the activity and size of hydatid cyst and other factors, the sensitivity and specificity are not ideal. This paper mainly introduces the research progress of hydatid immunology diagnosis at home and abroad to guide the practical application of hydatid prevention and treatment.

China Tropical Medicine, 2021, Vol 21, Issue 6, p600

1009-9727

Academic Journal

10.13604/j.cnki.46-1064/r.2021.06.19