This article explores the connection between Edgar Allan Poe's writings and scientific themes. It discusses how scholars have analyzed Poe's work throughout history, focusing on his use of various scientific disciplines. The article also highlights the relevance of Poe's writings to contemporary concerns, such as ecology and the COVID-19 pandemic. It emphasizes the importance of considering diverse perspectives and the potential for new discoveries in understanding Poe's work and its relationship to science. The text also discusses the limitations and potential negative effects of science, while acknowledging the potential for a more balanced and harmonious approach.