Works matching DE "CHECKPOINT kinase 2"
Results: 142
Real-world data on the prevalence of BRCA1/2 and HRR gene mutations in patients with primary and metastatic castration resistant prostate cancer.
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- World Journal of Urology, 2024, v. 42, n. 1, p. 1, doi. 10.1007/s00345-024-05188-7
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- Article
Chk2 在 Bmi1 缺失所致的肾脏早衰和纤维化中的作用和机制研究.
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- Progress in Modern Biomedicine, 2023, v. 23, n. 16, p. 3001, doi. 10.13241/j.cnki.pmb.2023.16.001
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- Article
Should we be testing for germline and "actionable" mutations in all glioma patients?
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- Neuro-Oncology Practice, 2025, v. 12, n. 1, p. 3, doi. 10.1093/nop/npae121
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- Article
Chk2 deficiency alleviates irradiation‐induced taste dysfunction by inhibiting p53‐dependent apoptosis.
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- Oral Diseases, 2018, v. 24, n. 5, p. 856, doi. 10.1111/odi.12822
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- Article
Comments on "The CHK2 kinase is recurrently mutated and functionally impaired in the germline of pediatric cancer patients".
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- International Journal of Cancer, 2023, v. 152, n. 9, p. 2011, doi. 10.1002/ijc.34432
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- Article
Reply to: Comments on "The CHK2 kinase is recurrently mutated and functionally impaired in the germline of pediatric cancer patients".
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- International Journal of Cancer, 2023, v. 152, n. 9, p. 2013, doi. 10.1002/ijc.34431
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- Article
The CHK2 kinase is recurrently mutated and functionally impaired in the germline of pediatric cancer patients.
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- International Journal of Cancer, 2023, v. 152, n. 7, p. 1388, doi. 10.1002/ijc.34390
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- Article
Checkpoint kinase 1/2 inhibition potentiates anti-tumoral immune response and sensitizes gliomas to immune checkpoint blockade.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-36878-2
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- Article
Comparing Cancer Risk Management between Females with Truncating CHEK2 1100delC versus Missense CHEK2 I157T Variants.
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- Genes, 2024, v. 15, n. 7, p. 881, doi. 10.3390/genes15070881
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- Article
Detection Rate and Spectrum of Pathogenic Variations in a Cohort of 83 Patients with Suspected Hereditary Risk of Kidney Cancer.
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- Genes, 2023, v. 14, n. 11, p. 1991, doi. 10.3390/genes14111991
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- Article
Impact of High-to-Moderate Penetrance Genes on Genetic Testing: Looking over Breast Cancer.
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- Genes, 2023, v. 14, n. 8, p. 1530, doi. 10.3390/genes14081530
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- Article
Comprehensive Clinical and Genetic Analysis of CHEK2 in Croatian Men with Prostate Cancer.
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- Genes, 2022, v. 13, n. 11, p. 1955, doi. 10.3390/genes13111955
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- Article
Association of CHEK2 I157T and SULT1A1 R213H genetic variants with risk of sporadic colorectal cancer in a sample of Egyptian patients.
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- Egyptian Journal of Medical Human Genetics, 2022, v. 23, p. 1, doi. 10.1186/s43042-022-00238-4
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- Article
Association of CHEK2 I157T and SULT1A1 R213H genetic variants with risk of sporadic colorectal cancer in a sample of Egyptian patients.
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- Egyptian Journal of Medical Human Genetics, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s43042-022-00238-4
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- Article
Prognostic role of CHEK2, FASN and Her2/neu Expression in Stage Ta-T1 Non-Muscle-Invasive Bladder Cancer (NMIBC).
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- Egyptian Journal of Hospital Medicine, 2023, v. 91, p. 5266, doi. 10.21608/ejhm.2023.305065
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- Article
Cell cycle-dependent localization of CHK2 at centrosomes during mitosis.
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- Cell Division, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1747-1028-8-7
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- Article
Double Heterozygous Pathogenic Variants in TP53 and CHEK2 in Boy with Undifferentiated Embryonal Sarcoma of the Liver.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 21, p. 11489, doi. 10.3390/ijms252111489
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- Article
Correlation between Molecular Docking and the Stabilizing Interaction of HOMO-LUMO: Spirostans in CHK1 and CHK2, an In Silico Cancer Approach.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 16, p. 8588, doi. 10.3390/ijms25168588
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- Article
Investigation into the Neuroprotective and Therapeutic Potential of Plant-Derived Chk2 Inhibitors.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 14, p. 7725, doi. 10.3390/ijms25147725
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- Article
Molecular Research and Treatment of Breast Cancer 2.0.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 7, p. 3932, doi. 10.3390/ijms25073932
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- Article
p53 Dysregulation in Breast Cancer: Insights on Mutations in the TP53 Network and p53 Isoform Expression.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 12, p. 10078, doi. 10.3390/ijms241210078
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- Article
Genomic Landscape of Normal and Breast Cancer Tissues in a Hungarian Pilot Cohort.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 10, p. 8553, doi. 10.3390/ijms24108553
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- Article
Plumbagin Exhibits Genotoxicity and Induces G2/M Cell Cycle Arrest via ROS-Mediated Oxidative Stress and Activation of ATM-p53 Signaling Pathway in Hepatocellular Cells.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 7, p. 6279, doi. 10.3390/ijms24076279
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- Article
Checkpoint Kinase 2 Inhibition Can Reverse Tamoxifen Resistance in ER-Positive Breast Cancer.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 20, p. 12290, doi. 10.3390/ijms232012290
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- Article
RYBP Sensitizes Cancer Cells to PARP Inhibitors by Regulating ATM Activity.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 19, p. 11764, doi. 10.3390/ijms231911764
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- Article
Wwox Binding to the Murine Brca1-BRCT Domain Regulates Timing of Brip1 and CtIP Phospho-Protein Interactions with This Domain at DNA Double-Strand Breaks, and Repair Pathway Choice.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 7, p. 3729, doi. 10.3390/ijms23073729
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- Article
Thyroid Cancer in Childhood Cancer Survivors: Demographic, Clinical, Germline Genetic Characteristics, Treatment, and Outcome.
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- Journal of Clinical Medicine, 2025, v. 14, n. 2, p. 589, doi. 10.3390/jcm14020589
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- Article
Further Association of Germline CHEK2 Loss-of-Function Variants with Testicular Germ Cell Tumors.
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- Journal of Clinical Medicine, 2023, v. 12, n. 22, p. 7065, doi. 10.3390/jcm12227065
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- Article
Overexpression of CHK1 and CHK2 in pediatric patients of B -acute lymphoblastic leukemia.
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- Iranian Journal of Pediatric Hematology & Oncology, 2023, v. 13, n. 4, p. 233, doi. 10.18502/ijpho.v13i4.13769
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- Article
Case report: Two sisters with a germline CHEK2 variant and distinct endocrine neoplasias.
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- Frontiers in Endocrinology, 2022, v. 13, p. 1, doi. 10.3389/fendo.2022.1024108
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- Article
Citrinin Provoke DNA Damage and Cell-Cycle Arrest Related to Chk2 and FANCD2 Checkpoint Proteins in Hepatocellular and Adenocarcinoma Cell Lines.
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- Toxins, 2024, v. 16, n. 7, p. 321, doi. 10.3390/toxins16070321
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- Article
Sterigmatocystin, 5-Methoxysterigmatocistin, and Their Combinations are Cytotoxic and Genotoxic to A549 and HepG2 Cells and Provoke Phosphorylation of Chk2, but not FANCD2 Checkpoint Proteins.
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- Toxins, 2021, v. 13, n. 7, p. 464, doi. 10.3390/toxins13070464
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- Article
Synchronous Papillary Thyroid Cancer and Colorectal Cancer in a Young Patient with a CHEK2 Mutation.
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- 2024
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- Case Study
FadA promotes DNA damage and progression of Fusobacterium nucleatum-induced colorectal cancer through up-regulation of chk2.
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- Journal of Experimental & Clinical Cancer Research (17569966), 2020, v. 39, n. 1, p. N.PAG, doi. 10.1186/s13046-020-01677-w
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- Article
NEDD4L affects stability of the CHEK2/TP53 axis through ubiquitination modification to enhance osteogenic differentiation of periodontal ligament stem cells.
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- Connective Tissue Research, 2024, v. 65, n. 6, p. 433, doi. 10.1080/03008207.2024.2406794
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- Article
Role of Breast Cancer Risk Estimation Models to Identify Women Eligible for Genetic Testing and Risk-Reducing Surgery.
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- Biomedicines, 2024, v. 12, n. 4, p. 714, doi. 10.3390/biomedicines12040714
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- Article
RNA Sequencing Provides Evidence for Pathogenicity of a Novel CHEK2 Splice Variant (C.1009-7T>G).
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- Annals of Laboratory Medicine, 2022, v. 42, n. 3, p. 380, doi. 10.3343/alm.2022.42.3.380
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- Article
The First Case Report of a Patient With Oligodendroglioma Harboring CHEK2 Germline Mutation.
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- Frontiers in Genetics, 2022, v. 13, p. 1, doi. 10.3389/fgene.2022.718689
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- Article
The 8<sup>th</sup> Biennial Meeting of Asian Society of Gynecologic Oncology.
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- Journal of Gynecologic Oncology, 2024, v. 35, p. S1
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- Article
The Role of Wild-Type p53 in Cisplatin-Induced Chk2 Phosphorylation and the Inhibition of PlatinumResistance with a Chk2 Inhibitor.
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- Chemotherapy Research & Practice, 2011, p. 1, doi. 10.1155/2011/715469
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- Article
DNA damage-related proteins in smokers and non-smokers with oral cancer.
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- Brazilian Oral Research, 2022, v. 36, p. 1, doi. 10.1590/1807-3107bor-2022.vol36.0027
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- Article
A Mitotic Phosphorylation Feedback Network Connects Cdk1, Plk1, 53BP1, and Chk2 to Inactivate the G<sub>2</sub>/M DNA Damage Checkpoint.
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- PLoS Biology, 2010, v. 8, n. 1, p. 1, doi. 10.1371/journal.pbio.1000287
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- Article
CHK2 Promotes Anoikis and is Associated with the Progression of Papillary Thyroid Cancer.
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- Cellular Physiology & Biochemistry (Karger AG), 2018, v. 45, n. 4, p. 1590, doi. 10.1159/000487724
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- Article
Understanding oocyte ageing.
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- Minerva Obstetrics & Gynecology, 2024, v. 76, n. 3, p. 284, doi. 10.23736/S2724-606X.24.05343-0
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- Article
New perspective on DNA response pathway (DDR) in glioblastoma, focus on classic biomarkers and emerging roles of ncRNAs.
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- Expert Reviews in Molecular Medicine, 2023, v. 25, p. 1, doi. 10.1017/erm.2023.10
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- Article
CHK2 is involved in the p53-independent radiosensitizing effects of valproic acid.
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- Oncology Letters, 2017, v. 13, n. 4, p. 2591, doi. 10.3892/ol.2017.5792
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- Article
Impact of homologous recombination repair/BReast CAncer (BRCA) gene alterations on survival in a real‐world setting of metastatic prostate cancer.
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- BJU International, 2025, v. 135, n. 1, p. 117, doi. 10.1111/bju.16462
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- Article
Is genetic testing coming of age in advanced prostate cancer?
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- BJU International, 2023, v. 132, n. 5, p. 496, doi. 10.1111/bju.16139
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- Article
A second hereditary cancer predisposition syndrome in a patient with lynch syndrome and three primary cancers.
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- 2024
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- Publication type:
- Case Study
Association of recurrent mutations in BRCA1, BRCA2, RAD51C, PALB2, and CHEK2 with the risk of borderline ovarian tumor.
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- Hereditary Cancer in Clinical Practice, 2022, v. 20, n. 1, p. 1, doi. 10.1186/s13053-022-00218-0
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- Article