框架眼镜联合角膜塑形镜矫正青少年高度近视的临床疗效及对角膜内皮细胞和泪膜的影响.

张洪波; 李树茂; 鲁向阳; 张惟虓; 王碧莹

To investigate the clinical efficacy of frame glasses combined with orthokeratology lens in correction of high myopia in adolescents and its influence on corneal endothelial cells and tear film. 98 cases (181 eyes) adolescent patients with high myopia who were admitted in our hospital from January 2018 to March 2019 were selected, they were divided into control group of 49 cases with 92 eyes (conventional frame glasses wearing treatment)and observation group of 49 cases with 89 eyes (orthokeratology on the basis of the control group) according to envelope drawing method. The uncorrected visual acuity, diopter, axial length, density and quantity of corneal endothelial cells, tear film situation and complications situation were compared between the two groups. The diopter of the observation group decreased after 1 month, 3 months, 6 months, 1 year after treatment (P0.05), and the uncorrected visual acuity increased than those of before treatment, 1 month, 3 months after treatment after 6 months, 1 year of treatment and the uncorrected visual acuity of 1 year after treatment was higher than those of 6 months after treatment P0.05). 1 year tear film rupture time (TBUT), non contact tear film rupture time (NTBUT) of the observation group were lower than those of before treatment, and was lower than the control group (P0.05). There was no difference in the incidence of complications between the two groups (P>0.05). Frame glasses combined with orthokeratology lens in adolescent high myopia, it can effectively correct the myopia diopter and improve the uncorrected visual acuity, there is no significant effect on corneal endothelial cells, and does not increase the incidence of complications, but it has a certain influence on the stability of human tear film, which is necessary to strengthen the examination of tear film before wearing glasses and follow-up after wearing glasses in clinical treatment

VISUAL acuity; ENDOTHELIAL cells; MYOPIA; ORTHOKERATOLOGY; CONTROL groups; TEENAGERS; PHOTOREFRACTIVE keratectomy; PHACOEMULSIFICATION

Progress in Modern Biomedicine, 2021, Vol 21, Issue 4, p645

1673-6273

Academic Journal

10.13241/j.cnki.pmb.2021.04.009