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- Title
Tyrosinase Inhibition Type of Isolated Compounds Obtained from Pachyrhizus erosus.
- Authors
Lukitaningsih, Endang; Bahi, Muhammad; Holzgrabe, Ulrike
- Abstract
In Indonesia, Bengkoang (Phacyrhizus erosus) have been used as one of cosmetics especially as sun screening and skin whitening materials. Six active compounds in Bengkoang with antioxidant and skin whitening activities have been isolated, namely daidzein, daidzin, genistin, (8,9)-furanyl-pterocarpan-3-ol, 4-(2-(furane-2-yl)ethyl)-2-methyl-2,5-dihydro-furane-3-carbaldehyde and 2-butoxy-2,5-bis(hydroxymethyl)-tetrahydrofurane-3,4-diol. According to literatures, the type of their tyrosinase inhibitory activity has not yet reported. The determination of whitening activity of each compound was evaluated by the evaluation of Lineweaver-Burk plot. The result showed that five compounds had competitive inhibitory activity and 8,9-furanyl-pterocarpan-3-ol showed a non-competitive inhibition.
- Subjects
INDONESIA; PHENOL oxidase; ENZYME inhibitors; PACHYRHIZUS; SUNSCREENS (Cosmetics); FADE creams (Cosmetics)
- Publication
Aceh International Journal of Science & Technology, 2013, Vol 2, Issue 3, p98
- ISSN
2088-9860
- Publication type
Academic Journal
- DOI
10.13170/AIJST.0203.05