Works matching DNA topoisomerase I

Results: 1625

Inhibitory Activities of Helichrysum Taxa on Mammalian Type I DNA Topoisomerase.

Published in:

Pharmaceutical Biology, 2006, v. 44, n. 3, p. 189, doi. 10.1080/13880200600685972

By:

Kucukoglu, O.;
Ozturk, B.;
Kamataki, T.;
Topcu, Z.

Publication type:

Article

Potential Inhibitors of Monkeypox Virus Revealed by Molecular Modeling Approach to Viral DNA Topoisomerase I.

Published in:

Molecules, 2023, v. 28, n. 3, p. 1444, doi. 10.3390/molecules28031444

By:

Hu, Xiaopeng;
An, Sanqi;
Chu, Jiemei;
Liang, Bingyu;
Liao, Yanyan;
Jiang, Junjun;
Lin, Yao;
Ye, Li;
Liang, Hao

Publication type:

Article

Boldine-Derived Alkaloids Inhibit the Activity of DNA Topoisomerase I and Growth of Mycobacterium tuberculosis.

Published in:

Frontiers in Microbiology, 2018, p. N.PAG, doi. 10.3389/fmicb.2018.01659

By:

García, María T.;
Carreño, David;
Tirado-Vélez, José M.;
Ferrándiz, María J.;
Rodrigues, Liliana;
Gracia, Begoña;
Amblar, Mónica;
Ainsa, José A.;
de la Campa, Adela G.

Publication type:

Article

Antileishmanial activity evaluation of bis-lawsone analogs and DNA topoisomerase-I inhibition studies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2014, v. 29, n. 2, p. 185, doi. 10.3109/14756366.2013.765413

By:

Sharma, Garima;
Chowdhury, Sayan;
Sinha, Suman;
Majumder, Hemanta K.;
Kumar, S. Vasanth

Publication type:

Article

Seconeolitsine, the Novel Inhibitor of DNA Topoisomerase I, Protects against Invasive Pneumococcal Disease Caused by Fluoroquinolone-Resistant Strains.

Published in:

Antibiotics (2079-6382), 2021, v. 10, n. 5, p. 573, doi. 10.3390/antibiotics10050573

By:

Tirado-Vélez, Jose Manuel;
Carreño, David;
Sevillano, David;
Alou, Luis;
Yuste, José;
de la Campa, Adela G.;
Simal-Gandara, Jesus

Publication type:

Article

Pharmacokinetics, tissue distribution, and metabolism of novel DNA topoisomerase I inhibitor yuanhuacine in rabbit.

Published in:

Xenobiotica, 2009, v. 39, n. 3, p. 273, doi. 10.1080/00498250802715987

By:

Zhang, S. X.;
Yang, P. W.;
Zhang, D. C.;
Dong, W. Q.;
Zhang, F. H.;
Sun, Y. M.

Publication type:

Article

Specific phosphorylation of SR proteins by mammalian DNA topoisomerase I.

Published in:

Nature, 1996, v. 381, n. 6577, p. 80, doi. 10.1038/381080a0

By:

Rossi, Ferdinand;
Labourier, Emmanuel

Publication type:

Article

Three-dimensional structure of the 67k N-terminal fragment of E. coli DNA topoisomerase I.

Published in:

Nature, 1994, v. 367, n. 6459, p. 138, doi. 10.1038/367138a0

By:

Lima, Christopher D.;
Wang, James C.

Publication type:

Article

Effects of the Cdc2-like kinase-family and DNA topoisomerase I on the alternative splicing of eNOS in TNF-α-stimulated human endothelial cells.

Published in:

Biological Chemistry, 2008, v. 389, n. 10, p. 1333, doi. 10.1515/BC.2008.152

By:

Eisenreich, Andreas;
Boltzen, Ulrike;
Poller, Wolfgang;
Schultheiss, Heinz-Peter;
Rauch, Ursula

Publication type:

Article

Regulation of gene expression, cellular localization, and in vivo function of Caenorhabditis elegans DNA topoisomerase I.

Published in:

Genes to Cells, 2001, v. 6, n. 4, p. 303, doi. 10.1046/j.1365-2443.2001.00423.x

By:

Lee, Myon Hee;
Park, Hyungki;
Shim, Gaegal;
Lee, Junho;
Koo, Hyeon-Sook

Publication type:

Article

Synthesis, characterization, and investigation of singlet oxygen, DNA interaction, and topoisomerase I inhibition properties of novel zinc(II) phthalocyanine.

Published in:

Turkish Journal of Chemistry, 2019, v. 43, n. 6, p. 1646, doi. 10.3906/kim-1909-32

By:

DEMİRBAŞ, Ümit

Publication type:

Article

Genetic Analysis of Saccharomyces cerevisiae H2A Serine 129 Mutant Suggests a Functional Relationship Between H2A and the Sister-Chromatid Cohesion Partners Csm3—Tof1 for the Repair of Topoisomerase I-Induced DNA Damage.

Published in:

Genetics, 2006, v. 172, n. 1, p. 67, doi. 10.1534/genetics.105.046128

By:

Redon, Christophe;
Pilch, Duane R.;
Bonner, William M.

Publication type:

Article

Transcription facilitated genome-wide recruitment of topoisomerase I and DNA gyrase.

Published in:

PLoS Genetics, 2017, v. 13, n. 5, p. 1, doi. 10.1371/journal.pgen.1006754

By:

Ahmed, Wareed;
Sala, Claudia;
Hegde, Shubhada R.;
Jha, Rajiv Kumar;
Cole, Stewart T.;
Nagaraja, Valakunja

Publication type:

Article

Corrigendum: 7-Ethyl-10-Hydroxycamptothecin, A DNA Topoisomerase I Inhibitor, Performs BRD4 Inhibitory Activity and Inhibits Human Leukemic Cell Growth.

Published in:

2021

By:

Wang, Airong;
Li, Lingling;
Li, Mengya;
Wang, Shujuan;
Wang, Chong

Publication type:

Correction Notice

Why Should DNA Topoisomerase I Have a Scaffold Activity?

Published in:

Biology (2079-7737), 2021, v. 10, n. 3, p. 190, doi. 10.3390/biology10030190

By:

Di Felice, Francesca;
Camilloni, Giorgio

Publication type:

Article

Raman Spectroscopy of Topotecan, an Inhibitor of DNA Topoisomerase I.

Published in:

Optics & Spectroscopy, 2002, v. 93, n. 4, p. 493, doi. 10.1134/1.1517071

By:

Mochalov, K. E.;
Ustinova, O. A.;
Strel’tsov, S. A.;
Grokhovskiı, S. L.;
Zhuze, A. L.;
Nabiev, I. R.;
Sukhanova, A. V.;
Oleınikov, V. A.

Publication type:

Article

Structural and Dynamical Effects Induced by the Anticancer Drug Topotecan on the Human Topoisomerase I -- DNA Complex.

Published in:

PLoS ONE, 2010, v. 5, n. 6, p. 1, doi. 10.1371/journal.pone.0010934

By:

Mancini, Giordano;
D'Annessa, Ilda;
Coletta, Andrea;
Sanna, Nico;
Chillemi, Giovanni;
Desideri, Alessandro

Publication type:

Article

DNA Interaction and Dual Topoisomerase I and II Inhibition Properties of the Anti-Tumor Drug Prodigiosin.

Published in:

Toxicological Sciences, 2005, v. 85, n. 2, p. 870, doi. 10.1093/toxsci/kfi149

By:

Montaner, Beatriz;
Castillo-Ávila, Wilmar;
Martinell, Marc;
Öllinger, Rupert;
Aymami, Joan;
Giralt, Ernest;
Pérez-Tomás, Ricardo

Publication type:

Article

Cytotoxic activity of 4′-hydroxychalcone derivatives against Jurkat cells and their effects on mammalian DNA topoisomerase I.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2009, v. 24, n. 3, p. 804, doi. 10.1080/14756360802399126

By:

Gul, Halise Inci;
Cizmecioglu, Murat;
Zencir, Sevil;
Gul, Mustafa;
Canturk, Pakize;
Atalay, Mustafa;
Topcu, Zeki

Publication type:

Article

Iridoids as DNA topoisomerase I poisons.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2005, v. 20, n. 4, p. 389, doi. 10.1080/14756360500141879

By:

Gálvez, Marina;
Martín-Cordero, Carmen;
Jesús Ayuso, María

Publication type:

Article

Apoptosis is induced in leishmanial cells by a novel protein kinase inhibitor withaferin A and is facilitated by apoptotic topoisomerase I–DNA complex.

Published in:

Cell Death & Differentiation, 2007, v. 14, n. 2, p. 358, doi. 10.1038/sj.cdd.4402002

By:

Sen, N.;
Banerjee, B.;
Das, B. B.;
Ganguly, A.;
Sen, T.;
Pramanik, S.;
Mukhopadhyay, S.;
Majumder, H. K.

Publication type:

Article

DNA topoisomerase I is involved in both repression and activation of transcription.

Published in:

Nature, 1993, v. 365, n. 6443, p. 227, doi. 10.1038/365227a0

By:

Merino, Alejandro;
Madden, Knut R.

Publication type:

Article

The distinctive cellular responses to DNA strand breaks caused by a DNA topoisomerase I poison in conjunction with DNA replication and RNA transcription.

Published in:

Genes & Genetic Systems, 2015, v. 90, n. 4, p. 187, doi. 10.1266/ggs.15-00023

By:

Ryo Sakasai;
Kuniyoshi Iwabuchi

Publication type:

Article

ANTHOCYANIN INTERACTIONS WITH DNA: INTERCALATION, TOPOISOMERASE I INHIBITION AND OXIDATIVE REACTIONS.

Published in:

Journal of Food Biochemistry, 2008, v. 32, n. 5, p. 576, doi. 10.1111/j.1745-4514.2008.00181.x

By:

WEBB, MICHAEL R.;
MIN, KYUNGMI;
EBELER, SUSAN E.

Publication type:

Article

Mutations of human DNA topoisomerase I at poly(ADP-ribose) binding sites: modulation of camptothecin activity by ADP-ribose polymers.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2014, v. 33, n. 1, p. 1, doi. 10.1186/s13046-014-0071-z

By:

Tesauro, Cinzia;
Graziani, Grazia;
Arnò, Barbara;
Zuccaro, Laura;
Muzi, Alessia;
D'Annessa, Ilda;
Santori, Elettra;
Tentori, Lucio;
Leonetti, Carlo;
Fiorani, Paola;
Desideri, Alessandro

Publication type:

Article

DNA-Binding and Topoisomerase-I-Suppressing Activities of Novel Vanadium Compound Van-7.

Published in:

Bioinorganic Chemistry & Applications, 2012, p. 1, doi. 10.1155/2012/756374

By:

Xiao-mei Mo;
Zhan-fang Chen;
Xin Qi;
Yan-tuan Li;
Jing Li

Publication type:

Article

Multiple gene copy number increases total protein expression and enzyme activity of DNA topoisomerase I in Pichia pastoris.

Published in:

World Academy of Sciences Journal, 2022, v. 4, n. 5, p. 1, doi. 10.3892/wasj.2022.167

By:

NUR ADILA FADZIL;
SHERN KWOK LIM;
AI LAN CHEW;
BOON YIN KHOO

Publication type:

Article

DB-1310, an ADC comprised of a novel anti-HER3 antibody conjugated to a DNA topoisomerase I inhibitor, is highly effective for the treatment of HER3-positive solid tumors.

Published in:

Journal of Translational Medicine, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12967-024-05133-7

By:

Li, Xi;
Yao, Jun;
Qu, Chen;
Luo, Lan;
Li, Bing;
Zhang, Yu;
Zhu, Zhongyuan;
Qiu, Yang;
Hua, Haiqing

Publication type:

Article

Isolation of mutants of Saccharomyces cerevisiae requiring DNA topoisomerase I.

Published in:

Genetics, 1995, v. 141, n. 2, p. 465, doi. 10.1093/genetics/141.2.465

By:

Sadoff, Ben U.;
Heath-Pagliuso, Sharon

Publication type:

Article

Activity of intoplicine (RP60475), a new DNA topoisomerase I and II inhibitor, against human...

Published in:

JNCI: Journal of the National Cancer Institute, 1994, v. 86, n. 1, p. 30, doi. 10.1093/jnci/86.1.30

By:

Eckardt, John R.;
Burris III, Howard A.

Publication type:

Article

Case Report: 7-Ethyl-10-Hydroxycamptothecin, a DNA Topoisomerase I Inhibitor, Performs BRD4 Inhibitory Activity and Inhibits Human Leukemic Cell Growth.

Published in:

Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2021.664176

By:

Wang, Airong;
Li, Lingling;
Li, Mengya;
Wang, Shujuan;
Wang, Chong

Publication type:

Article

International consensus on antinuclear antibody patterns: definition of the AC-29 pattern associated with antibodies to DNA topoisomerase I.

Published in:

Clinical Chemistry & Laboratory Medicine, 2018, v. 56, n. 10, p. 1783, doi. 10.1515/cclm-2018-0188

By:

Andrade, Luis E. C.;
Klotz, Werner;
Herold, Manfred;
Conrad, Karsten;
Rönnelid, Johan;
Fritzler, Marvin J.;
von Mühlen, Carlos A.;
Satoh, Minoru;
Damoiseaux, Jan;
de Melo Cruvinel, Wilson;
Chan, Edward K. L.

Publication type:

Article

Genome-wide proximity between RNA polymerase and DNA topoisomerase I supports transcription in Streptococcus pneumoniae.

Published in:

PLoS Genetics, 2021, v. 17, n. 4, p. 1, doi. 10.1371/journal.pgen.1009542

By:

Ferrándiz, María-José;
Hernández, Pablo;
de la Campa, Adela G.

Publication type:

Article

Redox Modulation of the Activity of DNA Topoisomerase I from Carrot (Daucus carota) Mitochondria.

Published in:

Doklady Biochemistry & Biophysics, 2001, v. 377, n. 1-6, p. 82, doi. 10.1023/A:1011523522080

By:

Konstantinov, Yu. M.;
Tarasenko, V. I.;
Rogozin, I. B.

Publication type:

Article

Flavonolignan Conjugates as DNA-binding Ligands and Topoisomerase I Inhibitors: Electrochemical and Electrophoretic Approaches.

Published in:

Electroanalysis, 2016, v. 28, n. 11, p. 2866, doi. 10.1002/elan.201600146

By:

Zatloukalová, Martina;
Vavříková, Eva;
Pontinha, Ana Dora Rodrigues;
Coufal, Jan;
Křen, Vladimír;
Fojta, Miroslav;
Ulrichová, Jitka;
Oliveira‐Brett, Ana Maria;
Vacek, Jan

Publication type:

Article

Conformational changes in E. coli DNA topoisomerase I.

Published in:

Nature Structural Biology, 1999, v. 6, n. 10, p. 918

By:

Feinberg, Hadar;
Lima, Christopher D.;
Mondragón, Alfonso

Publication type:

Article

Protein?nucleotide interactions in E. coli DNA topoisomerase I.

Published in:

Nature Structural Biology, 1999, v. 6, n. 10, p. 961

By:

Feinberg, Hadar;
Changela, Anita;
Mondragón, Alfonso

Publication type:

Article

Development of DNA delivery system using Pseudomonas exotoxin A and a DNA binding region of human DNA topoisomerase I.

Published in:

Applied Microbiology & Biotechnology, 2000, v. 53, n. 5, p. 558, doi. 10.1007/s002530051657

By:

Chen, T.-Y.;
Hsu, C.-T.;
Chang, K.-H.;
Ting, C.-Y.;
Whang-Peng, J.;
Hui, C.-F.;
Hwang, J.

Publication type:

Article

DNA topoisomerase I and IIα expression in penile carcinomas: assessing potential tumour chemosensitivity.

Published in:

BJU International, 2008, v. 102, n. 8, p. 1040, doi. 10.1111/j.1464-410X.2008.07698.x

By:

Berney, Daniel M.;
Stankiewicz, Elzbieta;
Adlan, Ahmed M.A.;
Kudahetti, Sakunthala;
Biedrzycki, Olaf J.;
Hadway, Paul;
Watkin, Nick;
Corbishley, Cathy

Publication type:

Article

<i>Mycoplasma fermentans</i> Inhibits the Activity of Cellular DNA Topoisomerase I by Activation of PARP1 and Alters the Efficacy of Its Anti-Cancer Inhibitor.

Published in:

PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0072377

By:

Afriat, Reuven;
Horowitz, Shulamith;
Priel, Esther

Publication type:

Article

Exploring DNA Topoisomerase I Ligand Space in Search of Novel Anticancer Agents.

Published in:

PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0025150

By:

Drwal, Malgorzata N.;
Agama, Keli;
Wakelin, Laurence P. G.;
Pommier, Yves;
Griffith, Renate

Publication type:

Article

DNA topoisomerases I and II in human mature sperm cells: characterization and unique properties.

Published in:

Human Reproduction, 2007, v. 22, n. 8, p. 2183, doi. 10.1093/humrep/dem170

By:

I. Har-Vardi;
R. Mali;
M. Breietman;
Y. Sonin;
S. Albotiano;
E. Levitas;
G. Potashnik;
E. Priel

Publication type:

Article

Comparative analysis of nuclear and mitochondrial DNA topoisomerase I from Zea mays.

Published in:

Molecular Biology, 2008, v. 42, n. 1, p. 79, doi. 10.1134/S0026893308010111

By:

Tarasenko, V. I.;
Katyshev, A. I.;
Kobzev, V. F.;
Konstantinov, Yu. M.

Publication type:

Article

Computer Analysis of Conformational and Physicochemical Properties of Nucleotide Sequences Cleavable by DNA Topoisomerase I.

Published in:

Molecular Biology, 2005, v. 39, n. 3, p. 430, doi. 10.1007/s11008-005-0058-0

By:

Oshchepkov, D. Yu.;
Bugreev, D. V.;
Kolchanov, N. A.;
Nevinsky, G. A.

Publication type:

Article

Interaction of Topotecan, DNA Topoisomerase I Inhibitor, with Double-Stranded Polydeoxyribonucleotides. 1. Topotecan Dimerization in Solution.

Published in:

Molecular Biology, 2001, v. 35, n. 3, p. 365, doi. 10.1023/A:1010422711817

By:

Strel'tsov, S. A.;
Grokhovskii, S. L.;
Kudelina, I. A.;
Oleinikov, V. A.;
Zhuze, A. L.

Publication type:

Article

Interaction of Topotecan, DNA Topoisomerase I Inhibitor, with Double-Stranded Polydeoxyribonucleotides. 2. Formation of Topotecan–DNA Complex Containing Several DNA Molecules.

Published in:

Molecular Biology, 2001, v. 35, n. 3, p. 374, doi. 10.1023/A:1010474728655

By:

Strel'tsov, S. A.;
Mikheikin, A. L.;
Nechipurenko, Yu. D.

Publication type:

Article

N-terminal domain of tyrosyl-DNA phosphodiesterase I regulates topoisomerase I-induced toxicity in cells.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-28564-6

By:

Brettrager, Evan J.;
Cuya, Selma M.;
Tibbs, Zachary E.;
Zhang, Jun;
Falany, Charles N.;
Aller, Stephen G.;
van Waardenburg, Robert C. A. M.

Publication type:

Article

The interference of piperidinopropionaphthone hydrochloride in mammalian type I and type II DNA topoisomerase reactions.

Published in:

Marmara Pharmaceutical Journal, 2015, v. 19, n. 2, p. 82, doi. 10.12991/mpj.2015199638

By:

ISTANBULLU, Huseyin;
ZENCIR, Sevil;
BERENYI, Agnes;
KILICKAYA, Pakize CANTURK;
ZUPKO, Istvan;
ERCIYAS, Ercin;
TOPCU, Zeki

Publication type:

Article

Potential use of Pichia pastoris strain SMD1168H expressing DNA topoisomerase I in the screening of potential anti-breast cancer agents.

Published in:

Molecular Medicine Reports, 2019, v. 19, n. 6, p. 5368, doi. 10.3892/mmr.2019.10201

By:

Xin, Jian;
Mahtar, Wan Nor Azlin Wan;
Siah, Poh Chiew;
Miswan, Noorizan;
Khoo, Boon Yin

Publication type:

Article

Antibacterial activity of a DNA topoisomerase I inhibitor versus fluoroquinolones in Streptococcus pneumoniae.

Published in:

PLoS ONE, 2020, v. 15, n. 11, p. N.PAG, doi. 10.1371/journal.pone.0241780

By:

Valenzuela, Myriam V.;
Domenech, Mirian;
Mateos-Martínez, Patricia;
González-Camacho, Fernando;
de la Campa, Adela G.;
García, Maria Teresa

Publication type:

Article