Works matching DE "LIGANDS (Biochemistry)"

Results: 5000

Harnessing NKG2D CAR-T cells with radiotherapy: a novel approach for esophageal squamous cell carcinoma treatment.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1589379

By:

Liu, Tianyu;
Fan, Liyuan;
Huang, Weicheng;
Chen, Pengxiang;
Liu, Yuchen;
Wang, Shuyun;
Guo, Kaiyue;
Cheng, Yufeng;
Han, Yali

Publication type:

Article

The pharmacological network of Tinospora cordifolia: Its role in regulating inflammation and cathelicidin production.

Published in:

Journal of Research in Pharmacy, 2025, v. 29, n. 3, p. 903, doi. 10.12991/jrespharm.1693737

By:

JAMIL, Ahmad Shobrun;
WIDYARTI, Sri;
SETIAWAN, Meddy;
RIFA'I, Muhaimin

Publication type:

Article

PD-1 is conserved from sharks to humans: new insights into PD-1, PD-L1, PD-L2, and SHP-2 evolution.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1573492

By:

Kondo, Ryohei;
Kondo, Kohei;
Nabeshima, Kei;
Nishikimi, Akihiko;
Ishida, Yasumasa;
Shigeoka, Toshiaki;
Dijkstra, Johannes M.

Publication type:

Article

Molecular Perspectives on Meningioma with Osseous Infiltration Revealed by 68Ga-DOTA TOC PET-CT.

Published in:

2025

By:

Usmani, Sharjeel;
Jain, Anjali;
Riyami, Khulood Al;
Hashmi, Syed Furqan;
Khalid, Jamsari;
Kheruka, Subhash

Publication type:

Case Study

Changes of Prostate-Specific Membrane Antigen-Radioligand Uptake on PET with Systemic Therapy in Patients with Metastatic Renal Cell Carcinoma.

Published in:

Cancers, 2025, v. 17, n. 11, p. 1736, doi. 10.3390/cancers17111736

By:

Kunte, Sophie Carina;
Holzgreve, Adrien;
Unterrainer, Marcus;
Zahner, Josef;
Schmid, Hans Peter;
Schöll, Magdalena;
Blajan, Iulia;
Sheikh, Gabriel T.;
Mehrens, Dirk;
Casuscelli, Jozefina;
Tamalunas, Alexander J.;
Werner, Rudolf A.;
Stief, Christian G.;
Staehler, Michael;
Unterrainer, Lena M.

Publication type:

Article

2,5-Dihydroxybenzoic Acid Ameliorates Metabolic Dysfunction-Associated Steatotic Liver Disease by Targeting the CCL2-CCR2 Axis to Reduce Lipid Accumulation.

Published in:

Nutrients, 2025, v. 17, n. 11, p. 1835, doi. 10.3390/nu17111835

By:

Hsiang, Chien-Yun;
Hsu, Kuang-Ting;
Lo, Hsin-Yi;
Hou, Yun-Jhu;
Ho, Tin-Yun

Publication type:

Article

Stromal Hedgehog Signaling Is Associated with Favorable Outcomes in Pancreatic Cancer.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5200, doi. 10.3390/ijms26115200

By:

Manoukian, Paul;
Damhofer, Helene;
Zhao, Lan;
van Laarhoven, Hanneke W. M.;
Bijlsma, Maarten F.

Publication type:

Article

Glucosylceramide Synthase, a Key Enzyme in Sphingolipid Metabolism, Regulates Expression of Genes Accounting for Cancer Drug Resistance.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5112, doi. 10.3390/ijms26115112

By:

Mostaq, Md Saqline;
Kang, Lin;
Patwardhan, Gauri A.;
Zhao, Yunfeng;
Shi, Runhua;
Liu, Yong-Yu

Publication type:

Article

Anti-Tumor Activities of Anti-Siglec-15 Chimeric Heavy-Chain Antibodies.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5068, doi. 10.3390/ijms26115068

By:

Cheng, Kexuan;
Guo, Jiazheng;
Li, Yating;
Kang, Qinglin;
Wang, Rong;
Luo, Longlong;
Wang, Wei;
Lu, Jiansheng

Publication type:

Article

Surface Modification, Toxicity, and Applications of Carbon Dots to Cancer Theranosis: A Review.

Published in:

Nanomaterials (2079-4991), 2025, v. 15, n. 11, p. 781, doi. 10.3390/nano15110781

By:

Tegafaw, Tirusew;
Mulugeta, Endale;
Zhao, Dejun;
Liu, Ying;
Chen, Xiaoran;
Baek, Ahrum;
Kim, Jihyun;
Chang, Yongmin;
Lee, Gang Ho

Publication type:

Article

Synthesis and Characterization of Photoswitchable Covalent Ligands for the β2‐Adrenoceptor.

Published in:

Angewandte Chemie, 2025, v. 137, n. 24, p. 1, doi. 10.1002/ange.202424038

By:

Wirth, Ulrike;
Neu, Eduard;
Provasi, Davide;
Feustel, Steffen;
Schmidt, Maximilian F.;
Hübner, Harald;
Weikert, Dorothée;
Filizola, Marta;
König, Burkhard;
Gmeiner, Peter

Publication type:

Article

Cyclopentadienyl Half‐Sandwich Rhodium(III) Azopyridine Anticancer Complexes with Activity Tuned by Ligand Substituents.

Published in:

ChemCatChem, 2025, v. 17, n. 11, p. 1, doi. 10.1002/cctc.202401863

By:

Lant, Edward C.;
Needham, Russell J.;
Zhang, Zijin;
Coverdale, James P. C.;
Clarkson, Guy J.;
Bagley, Ian;
Dallmann, Robert;
Sadler, Peter J.

Publication type:

Article

Mutations that prevent phosphorylation of the BMP4 prodomain impair proteolytic maturation of homodimers leading to lethality in mice.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.105018

By:

Hyung-Seok Kim;
Sanchez, Mary L.;
Silva, Joshua;
Schubert, Heidi L.;
Dennis, Rebecca;
Hill, Christopher P.;
Christian, Jan L.

Publication type:

Article

Clustering Zwitterionic Amino Acids at the Upper Rim of Cone Calix[4]arene Triggers the Selective Recognition of Gram‐Negative Bacterial Envelope.

Published in:

Small Structures, 2025, v. 6, n. 6, p. 1, doi. 10.1002/sstr.202400547

By:

Rispoli, Francesco;
Moretti, Luca;
Vezzoni, Carlo Alberto;
Tosi, Eloisa;
Molteni, Linda;
Ciaramelli, Carlotta;
Marchiò, Luciano;
Volpi, Stefano;
Baldini, Laura;
Sansone, Francesco;
Palmioli, Alessandro;
Airoldi, Cristina;
Casnati, Alessandro

Publication type:

Article

Evaluation of Multidentate Ligands Derived from Ethyl 1,2,4‐triazine‐3‐carboxylate Building Blocks as Potential An(III)‐Selective Extractants for Nuclear Reprocessing.

Published in:

ChemistryOpen, 2025, v. 14, n. 6, p. 1, doi. 10.1002/open.202400306

By:

Zaytsev, Andrey V.;
Distler, Petr;
John, Jan;
Wilden, Andreas;
Modolo, Giuseppe;
Sims, Mark;
Lewis, Frank W.

Publication type:

Article

Evaluation of a host-protein signature score for differentiating between bacterial and viral infections: real-life evidence from a German tertiary hospital.

Published in:

Infection, 2025, v. 53, n. 3, p. 883, doi. 10.1007/s15010-024-02384-w

By:

Wagner, Laura;
Schneider, Heike;
Luppa, Peter B.;
Schröder, Kathrin;
Wantia, Nina;
Querbach, Christiane;
Jeske, Samuel D.;
Lahmer, Tobias;
Rothe, Kathrin;
Dibos, Miriam;
Voit, Florian;
Erber, Johanna;
Spinner, Christoph D.;
Schneider, Jochen;
Triebelhorn, Julian

Publication type:

Article

Using low-molecular-weight ligands for targeting in integrated chemodynamic/starvation therapy and chemotherapy for prostate cancer.

Published in:

Cancer Nanotechnology (1868-6958), 2025, v. 16, n. 1, p. 1, doi. 10.1186/s12645-025-00325-2

By:

Zhang, Xiaoli;
He, Jie;
An, Yu;
Jiang, Kehua;
Wang, Qing;
Deng, Wenrui;
Yang, Qiqi;
Sun, Fa;
Chen, Kun

Publication type:

Article

A Copper(I) Catenane Decorated Metal–Organic Layer as a Heterogenous Catalyst for Dehydrogenative Cross‐Coupling.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 31, p. 1, doi. 10.1002/chem.202500866

By:

Shi, Yi‐Xiang;
Zhu, Lihui;
Doan, Hoai Son;
Deng, Yulin;
Mo, Xiaoyong;
Wang, Yufeng;
Tse, Edmund C. M.;
Au‐Yeung, Ho Yu

Publication type:

Article

Exploring kartogenin: advances in therapeutics and signaling mechanisms for musculoskeletal regeneration.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10653-6

By:

Kiani, Sareh;
Fallahi, Jafar;
Tanideh, Nader;
Razban, Vahid;
Khajeh, Sahar

Publication type:

Article

Research Progress of CLE and Its Prospects in Woody Plants.

Published in:

Plants (2223-7747), 2025, v. 14, n. 10, p. 1424, doi. 10.3390/plants14101424

By:

Song, Zewen;
Zhou, Wenjun;
Jiang, Hanyu;
Duan, Yifan

Publication type:

Article

Green Synthesis of Nanoscale Mixed‐Ligand Complexes: DNA Interaction, Biomedical Applications, and Computational Studies.

Published in:

Applied Organometallic Chemistry, 2025, v. 39, n. 6, p. 1, doi. 10.1002/aoc.70230

By:

Hosny, Shimaa;
Abu‐Dief, Ahmed M.;
Farhan, Nasser;
Shehata, Mohamed R.;
Abd El‐Baki, Randa F.

Publication type:

Article

Nickel nanomaterials as delivery system in combating diseases.

Published in:

Journal of Drug Delivery & Therapeutics, 2025, v. 15, n. 5, p. 166, doi. 10.22270/jddt.v15i5.7124

By:

Mandal, Ardhendu Kumar

Publication type:

Article

Advances in the Functionalization of Vaccine Delivery Systems: Innovative Strategies and Translational Perspectives.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 640, doi. 10.3390/pharmaceutics17050640

By:

de Moura, Ingrid Andrêssa;
Silva, Anna Jéssica Duarte;
de Macêdo, Larissa Silva;
Melo, Karina Mayumi Tani Bezerra de;
Leal, Lígia Rosa Sales;
Espinoza, Benigno Cristofer Flores;
Invenção, Maria da Conceição Viana;
Pinho, Samara Sousa de;
Freitas, Antonio Carlos de

Publication type:

Article

Efficient Delivery of SARS-CoV-2 Plasmid DNA in HEK-293T Cells Using Chitosan Nanoparticles.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 5, p. 683, doi. 10.3390/ph18050683

By:

Mendoza-Guevara, Citlali Cecilia;
Martinez-Escobar, Alejandro;
Ramos-Godínez, María del Pilar;
Muñoz-Medina, José Esteban;
Ramon-Gallegos, Eva

Publication type:

Article

Quinoline Quest: Kynurenic Acid Strategies for Next-Generation Therapeutics via Rational Drug Design.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 5, p. 607, doi. 10.3390/ph18050607

By:

Tanaka, Masaru;
Szatmári, István;
Vécsei, László

Publication type:

Article

Positron Emission Tomography Radiotracers for Identification of Site of Recurrence in Prostate Cancer After Primary Treatment Failure.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1723, doi. 10.3390/cancers17101723

By:

Bitar, Ryan;
Zurita, Pablo;
Martiniova, Lucia;
Zurita, Amado J.;
Ravizzini, Gregory C.

Publication type:

Article

Insights into Chemoreceptor MCP2201-Sensing D-Malate.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4902, doi. 10.3390/ijms26104902

By:

Cui, Rui;
Li, Jie;
Hong, Yuan;
Guo, Lu;
Wang, Yun-Hao;
Bai, Yi-Fei;
Li, De-Feng

Publication type:

Article

Kisspeptin Receptor Agonists and Antagonists: Strategies for Discovery and Implications for Human Health and Disease.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4890, doi. 10.3390/ijms26104890

By:

Chen, Xing;
Yang, Shu;
Shaw, Natalie D.;
Xia, Menghang

Publication type:

Article

Discovery and Functional Validation of EP3 Receptor Ligands with Therapeutic Potential in Cardiovascular Disease.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4879, doi. 10.3390/ijms26104879

By:

Alonso-Fernández, Jorge-Ricardo;
Montoro-García, Silvia;
Cruz, Andreia-Filipa;
Ponce-Valencia, Alicia;
Carmena-Bargueño, Miguel;
Pérez-Sánchez, Horacio

Publication type:

Article

Identification of genetically engineered strategies to manipulate nano-platforms presenting immunotherapeutic ligands for alleviating primary ovarian insufficiency progression.

Published in:

Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02226-8

By:

Zhou, Guannan;
Gu, Yuanyuan;
Zhang, Menglei;
Ding, Jingxin;
Lu, Guanming;
Hua, Keqin;
Shen, Fang

Publication type:

Article

Iridium‐Catalyzed Asymmetric Allenylic Substitution via Kinetic Resolution Enabled by New Monodentate Ligands.

Published in:

Angewandte Chemie, 2025, v. 137, n. 23, p. 1, doi. 10.1002/ange.202506350

By:

Tu, Youshao;
Lin, Xiangfeng;
Lin, Jie;
Zhang, Chaoshen;
Sun, Jianwei

Publication type:

Article

Isolable Three‐Coordinate Base‐Stabilized Alumylene: A Precursor of Persistent Acceptor‐Free Monomeric Aluminum Oxide.

Published in:

Angewandte Chemie, 2025, v. 137, n. 23, p. 1, doi. 10.1002/ange.202505181

By:

Baeza, José Miguel León;
Xu, Huihui;
Takahashi, Shintaro;
Baceiredo, Antoine;
Guerrero, Rene Segundo Rojas;
Hashizume, Daisuke;
Saffon‐Merceron, Nathalie;
Branchadell, Vicenç;
Kato, Tsuyoshi

Publication type:

Article

Identification of lung adenocarcinoma subtypes based on mitochondrial energy metabolism-related genes.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2025, v. 44, n. 7, p. 568, doi. 10.1080/15257770.2024.2369093

By:

Ding, Jianyang;
Chen, Keng;
Wu, Xuhui

Publication type:

Article

Bone Biology and the Role of the RANK Ligand Pathway.

Published in:

Oncology (08909091), 2009, v. 23, p. 9

By:

Murthy, Rashmi K.;
Morrow, P. K.;
Theriault, Richard L.

Publication type:

Article

Infusion Reactions to Monoclonal Antibodies for Solid Tumors: Immunologic Mechanisms and Risk Factors.

Published in:

Oncology (08909091), 2009, v. 23, n. 2, p. 14

By:

Chung, Christine H.;
O'Neil, Bert H.

Publication type:

Article

Molecular Targets on Blood Vessels for Cancer Therapies in Clinical Trials.

Published in:

Oncology (08909091), 2007, v. 21, n. 11, p. 1346

By:

Sato, Masanori;
Arap, Wadih;
Pasqualini, Renata

Publication type:

Article

Molecular prejudice: RNA discrimination against purines allows response to a cellular alarm.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 10, p. 754, doi. 10.1038/nsmb.3095

By:

Ruehle, Marisa D;
Kieft, Jeffrey S

Publication type:

Article

Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 7, p. 522, doi. 10.1038/nsmb.3051

By:

Do Kwon, Young;
Pancera, Marie;
Acharya, Priyamvada;
Georgiev, Ivelin S;
Crooks, Emma T;
Gorman, Jason;
Joyce, M Gordon;
Guttman, Miklos;
Ma, Xiaochu;
Narpala, Sandeep;
Soto, Cinque;
Terry, Daniel S;
Yang, Yongping;
Zhou, Tongqing;
Ahlsen, Goran;
Bailer, Robert T;
Chambers, Michael;
Chuang, Gwo-Yu;
Doria-Rose, Nicole A;
Druz, Aliaksandr

Publication type:

Article

PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 5, p. 362, doi. 10.1038/nsmb.3014

By:

Kroeze, Wesley K;
Sassano, Maria F;
Huang, Xi-Ping;
Lansu, Katherine;
McCorvy, John D;
Giguère, Patrick M;
Sciaky, Noah;
Roth, Bryan L

Publication type:

Article

Conformational dynamics in substrate-binding domains influences transport in the ABC importer GlnPQ.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 1, p. 57, doi. 10.1038/nsmb.2929

By:

Gouridis, Giorgos;
Schuurman-Wolters, Gea K;
Ploetz, Evelyn;
Husada, Florence;
Vietrov, Ruslan;
de Boer, Marijn;
Cordes, Thorben;
Poolman, Bert

Publication type:

Article

Structural determinants of integrin β-subunit specificity for latent TGF-β.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 12, p. 1091, doi. 10.1038/nsmb.2905

By:

Dong, Xianchi;
Hudson, Nathan E;
Lu, Chafen;
Springer, Timothy A

Publication type:

Article

Evidence for a group II intron-like catalytic triplex in the spliceosome.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 5, p. 464, doi. 10.1038/nsmb.2815

By:

Fica, Sebastian M;
Mefford, Melissa A;
Piccirilli, Joseph A;
Staley, Jonathan P

Publication type:

Article

Conformational dynamics of ligand-dependent alternating access in LeuT.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 5, p. 472, doi. 10.1038/nsmb.2816

By:

Kazmier, Kelli;
Sharma, Shruti;
Quick, Matthias;
Islam, Shahidul M;
Roux, Benoît;
Weinstein, Harel;
Javitch, Jonathan A;
Mchaourab, Hassane S

Publication type:

Article

DNA is all the RAGE.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 11, p. 1242, doi. 10.1038/nsmb.2714

By:

Chen, Inês

Publication type:

Article

Defining the structural relationship between kainate-receptor deactivation and desensitization.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 9, p. 1054, doi. 10.1038/nsmb.2654

By:

Dawe, G Brent;
Musgaard, Maria;
Andrews, Elizabeth D;
Daniels, Bryan A;
Aurousseau, Mark R P;
Biggin, Philip C;
Bowie, Derek

Publication type:

Article

Unraveling the structural basis of GPCR activation and inactivation.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 5, p. 539, doi. 10.1038/nsmb.2584

By:

Bouvier, Michel

Publication type:

Article

Crystal structure of oligomeric β1-adrenergic G protein-coupled receptors in ligand-free basal state.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 4, p. 419, doi. 10.1038/nsmb.2504

By:

Huang, Jianyun;
Chen, Shuai;
Zhang, J Jillian;
Huang, Xin-Yun

Publication type:

Article

A direct interaction between DCP1 and XRN1 couples mRNA decapping to 5? exonucleolytic degradation.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 12, p. 1324, doi. 10.1038/nsmb.2413

By:

Braun, Joerg E;
Truffault, Vincent;
Boland, Andreas;
Huntzinger, Eric;
Chang, Chung-Te;
Haas, Gabrielle;
Weichenrieder, Oliver;
Coles, Murray;
Izaurralde, Elisa

Publication type:

Article

Crystal structures of STING protein reveal basis for recognition of cyclic di-GMP.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 7, p. 725, doi. 10.1038/nsmb.2332

By:

Shang, Guijun;
Zhu, Deyu;
Li, Ning;
Zhang, Junbing;
Zhu, Chunyuan;
Lu, Defen;
Liu, Cuilan;
Yu, Qian;
Zhao, Yanyu;
Xu, Sujuan;
Gu, Lichuan

Publication type:

Article

Synergistic substrate binding determines the stoichiometry of transport of a prokaryotic H+/Cl? exchanger.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 5, p. 525, doi. 10.1038/nsmb.2277

By:

Picollo, Alessandra;
Xu, Yanyan;
Johner, Niklaus;
Bernèche, Simon;
Accardi, Alessio

Publication type:

Article