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Gene expression changes caused by the p38 MAPK inhibitor dilmapimod in COPD patients: analysis of blood and sputum samples from a randomized, placebo-controlled clinical trial.
Published in:
Pharmacology Research & Perspectives, 2015, v. 3, n. 1, p. n/a, doi. 10.1002/prp2.94
By:
- Betts, Joanna C.;
- Mayer, Ruth J.;
- Tal ‐ Singer, Ruth;
- Warnock, Linda;
- Clayton, Chris;
- Bates, Stewart;
- Hoffman, Bryan E.;
- Larminie, Christopher;
- Singh, Dave
Publication type:
Article
Long‐term trends of COPD mortality: Gaps and opportunities.
Published in:
Respirology, 2022, v. 27, n. 11, p. 914, doi. 10.1111/resp.14334
By:
- Mannino, David M.;
- Tal‐Singer, Ruth
Publication type:
Article
A diVIsive Shuffling Approach (VIStA) for gene expression analysis to identify subtypes in Chronic Obstructive Pulmonary Disease.
Published in:
BMC Systems Biology, 2014, v. 8, n. Suppl 2, p. 1, doi. 10.1186/1752-0509-8-S2-S8
By:
- Menche, Jörg;
- Sharma1,2, Amitabh;
- Cho, Michael H.;
- Mayer, Ruth J.;
- Rennard, Stephen I.;
- Celli, Bartolome;
- Miller, Bruce E.;
- Locantore, Nick;
- Tal-Singer, Ruth;
- Ghosh, Soumitra;
- Larminie, Chris;
- Bradley, Glyn;
- Riley, John H.;
- Agusti, Alvar;
- Silverman, Edwin K.;
- Barabási, Albert-László
Publication type:
Article
Validation of Constant Work Rate Cycling Endurance Time for Use in Chronic Obstructive Pulmonary Disease Clinical Trials.
Published in:
Annals of the American Thoracic Society, 2024, v. 21, n. 5, p. 727, doi. 10.1513/AnnalsATS.202305-480OC
By:
- Casaburi, Richard;
- Merrill, Debora;
- Leidy, Nancy Kline;
- Locantore, Nicholas;
- Dolmage, Thomas;
- Garcia-Aymerich, Judith;
- Goldstein, Roger;
- Harding, Gale;
- Maltais, François;
- O'Donnell, Denis;
- Porszasz, Janos;
- Puente-Maestu, Luis;
- Rennard, Stephen;
- Rossiter, Harry B.;
- Sciurba, Frank;
- Spruit, Martijn A.;
- Tal-Singer, Ruth;
- Tetzlaff, Kay;
- van't Hul, Alex;
- Yu, Ren
Publication type:
Article
Differences in pathogenicity of herpes simplex virus serotypes 1 and 2 may be observed by histopathology and high-resolution magnetic resonance imaging in a murine encephalitis model.
Published in:
Journal of NeuroVirology, 2001, v. 7, n. 2, p. 105, doi. 10.1080/13550280152058762
By:
- Thomas, Heath C.;
- Kapadia, Rasesh D.;
- Wells, Grace I.;
- Gresham, Andrew M.;
- Sutton, David;
- Solleveld, Henk A.;
- Sarkar, Susanta K.;
- Dillon, Susan B.;
- Tal-Singer, Ruth
Publication type:
Article
A Telemedicine Approach for Monitoring COPD: A Prospective Feasibility and Acceptability Cohort Study.
Published in:
International Journal of COPD, 2022, v. 17, p. 2931, doi. 10.2147/COPD.S375049
By:
- Shinoda, Masahiro;
- Hataji, Osamu;
- Miura, Motohiko;
- Kinoshita, Masaharu;
- Mizoo, Akira;
- Tobino, Kazunori;
- Soutome, Toru;
- Nishi, Takanobu;
- Ishii, Takeo;
- Miller, Bruce E;
- Tal-Singer, Ruth;
- Tomlinson, Ryan;
- Matsuki, Taizo;
- Jones, Paul W;
- Shibata, Yoko
Publication type:
Article
Prevalence and Characteristics of Individuals with Preserved Ratio Impaired Spirometry (PRISm) and/or Impaired Lung Function in Japan: The OCEAN Study.
Published in:
International Journal of COPD, 2021, v. 16, p. 2665, doi. 10.2147/COPD.S322041
By:
- Kaise, Toshihiko;
- Sakihara, Eishin;
- Tamaki, Kentaro;
- Miyata, Hiroaki;
- Hirahara, Norimichi;
- Kirichek, Oksana;
- Tawara, Ryosuke;
- Akiyama, Shoko;
- Katsumata, Masayuki;
- Haruya, Mei;
- Ishii, Takeo;
- Simard, Edgar P;
- Miller, Bruce E;
- Tal-Singer, Ruth
Publication type:
Article
Utility of Self-Administered Questionnaires for Identifying Individuals at Risk of COPD in Japan: The OCEAN (Okinawa COPD casE finding AssessmeNt) Study.
Published in:
International Journal of COPD, 2021, v. 16, p. 1771, doi. 10.2147/COPD.S302259
By:
- Tamaki, Kentaro;
- Sakihara, Eishin;
- Miyata, Hiroaki;
- Hirahara, Norimichi;
- Kirichek, Oksana;
- Tawara, Ryosuke;
- Akiyama, Shoko;
- Katsumata, Masayuki;
- Haruya, Mei;
- Ishii, Takeo;
- Simard, Edgar P;
- Miller, Bruce E;
- Tal-Singer, Ruth;
- Kaise, Toshihiko
Publication type:
Article
A Prospective Cohort Study to Assess Obstructive Respiratory Disease Phenotypes and Endotypes in Japan: The TRAIT Study Design.
Published in:
International Journal of COPD, 2021, v. 16, p. 1813, doi. 10.2147/COPD.S308327
By:
- Hizawa, Nobuyuki;
- Fukunaga, Koichi;
- Sugiura, Hisatoshi;
- Nakano, Yasutaka;
- Kato, Motokazu;
- Sugiyama, Yutaro;
- Hanazawa, Tomohiro;
- Kaise, Toshihiko;
- Tal-Singer, Ruth;
- Jones, Paul W;
- Barnes, Neil;
- Compton, Chris;
- Ishii, Takeo
Publication type:
Article
Defining Chronic Mucus Hypersecretion Using the CAT in the SPIROMICS Cohort.
Published in:
International Journal of COPD, 2020, v. 15, p. 2467, doi. 10.2147/COPD.S267002
By:
- Stott-Miller, Marni;
- Müllerová, Hana;
- Miller, Bruce;
- Tabberer, Maggie;
- Baou, Céline El;
- Keeley, Tom;
- Martinez, Fernando J;
- Han, Meilan;
- Dransfield, Mark;
- Hansel, Nadia N;
- Cooper, Christopher B;
- Woodruff, Prescott;
- Ortega, Victor E;
- Comellas, Alejandro P;
- III, Robert Paine;
- Kanner, Richard E;
- Anderson, Wayne;
- Drummond, M Bradley;
- Kim, Victor;
- Tal-Singer, Ruth
Publication type:
Article
Increased von Willebrand Factor Processing in COPD, Reflecting Lung Epithelium Damage, Is Associated with Emphysema, Exacerbations and Elevated Mortality Risk.
Published in:
International Journal of COPD, 2020, v. 15, p. 543, doi. 10.2147/COPD.S235673
By:
- Langholm, Lasse L;
- Rønnow, Sarah Rank;
- Sand, Jannie MB;
- Leeming, Diana Julie;
- Tal-Singer, Ruth;
- Miller, Bruce E;
- Vestbo, Jørgen;
- Karsdal, Morten A;
- Manon-Jensen, Tina
Publication type:
Article
Fibrinogen, chronic obstructive pulmonary disease (COPD) and outcomes in two United States cohorts.
Published in:
International Journal of COPD, 2012, v. 7, p. 173, doi. 10.2147/COPD.S29892
By:
- Valvi, Deepa;
- Mannino, David M.;
- Müllerova, Hana;
- Tal-Singer, Ruth
Publication type:
Article
Negative Food Effect of Danirixin: Use of PBPK Modelling to Explore the Effect of Formulation and Meal Type on Clinical PK.
Published in:
Pharmaceutical Research, 2020, v. 37, n. 12, p. 1, doi. 10.1007/s11095-020-02948-z
By:
- Lloyd, Richard S.;
- Hingle, Martin I.;
- Bloomer, Jackie C.;
- Charles, Stephen J.;
- Butler, James M.;
- Paul, Alan;
- Zhu, Xiaofeng;
- Miller, Bruce;
- D'Amico, Donald;
- Donald, Alison;
- Tal-Singer, Ruth;
- Ambery, Claire
Publication type:
Article
Herpes Simplex Virus Glycoprotein C is a Receptor for Complement Component iC3b.
Published in:
Journal of Infectious Diseases, 1991, v. 164, n. 4, p. 750
By:
- Tal-Singer, Ruth;
- Seidel-Dugan, Cynthia;
- Fries, Louis;
- Huemer, Hartwig P.;
- Eisenberg, Roselyn J.;
- Cohen, Gary H.;
- Friedman, Harvey M.
Publication type:
Article
Altered Gene Expression in Blood and Sputum in COPD Frequent Exacerbators in the ECLIPSE Cohort.
Published in:
PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0107381
By:
- Singh, Dave;
- Fox, Steven M.;
- Tal-Singer, Ruth;
- Bates, Stewart;
- Riley, John H.;
- Celli, Bartolome
Publication type:
Article
Persistent Systemic Inflammation is Associated with Poor Clinical Outcomes in COPD: A Novel Phenotype.
Published in:
PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0037483
By:
- Agustí, Alvar;
- Edwards, Lisa D.;
- Rennard, Stephen I.;
- MacNee, William;
- Tal-Singer, Ruth;
- Miller, Bruce E.;
- Vestbo, Jørgen;
- Lomas, David A.;
- Calverley, Peter M. A.;
- Wouters, Emiel;
- Crim, Courtney;
- Yates, Julie C.;
- Silverman, Edwin K.;
- Coxson, Harvey O.;
- Bakke, Per;
- Mayer, Ruth J.;
- Celli, Bartolome
Publication type:
Article
Genetics of Sputum Gene Expression in Chronic Obstructive Pulmonary Disease.
Published in:
PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0024395
By:
- Qiu, Weiliang;
- Cho, Michael H.;
- Riley, John H.;
- Anderson, Wayne H.;
- Singh, Dave;
- Bakke, Per;
- Gulsvik, Amund;
- Litonjua, Augusto A.;
- Lomas, David A.;
- Crapo, James D.;
- Beaty, Terri H.;
- Celli, Bartolome R.;
- Rennard, Stephen;
- Tal-Singer, Ruth;
- Fox, Steven M.;
- Silverman, Edwin K.;
- Hersh, Craig P.
Publication type:
Article
Heterogeneity of quadriceps muscle phenotype in chronic obstructive pulmonary disease (Copd); implications for stratified medicine?
Published in:
2013
By:
- Natanek, Samantha A;
- Gosker, Harry R;
- Slot, Ilse G M;
- Marsh, Gemma S;
- Hopkinson, Nicholas S;
- Man, William D-C;
- Tal-Singer, Ruth;
- Moxham, John;
- Kemp, Paul R;
- Schols, Annemie M W J;
- Polkey, Michael I
Publication type:
journal article
Heterogeneity of quadriceps muscle phenotype in chronic obstructive pulmonary disease ( Copd); implications for stratified medicine?
Published in:
Muscle & Nerve, 2013, v. 48, n. 4, p. 488, doi. 10.1002/mus.23784
By:
- Natanek, Samantha A.;
- Gosker, Harry R.;
- Slot, Ilse G.M.;
- Marsh, Gemma S.;
- Hopkinson, Nicholas S.;
- Man, William D.‐C.;
- Tal‐Singer, Ruth;
- Moxham, John;
- Kemp, Paul R.;
- Schols, Annemie M.W.J.;
- Polkey, Michael I.
Publication type:
Article
An Update on Outcomes for COPD Pharmacological Trials: A COPD Investigators Report - Reassessment of the 2008 American Thoracic Society/European Respiratory Society Statement on Outcomes for COPD Pharmacological Trials.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2023, v. 208, n. 4, p. 374, doi. 10.1164/rccm.202303-0400SO
By:
- Cazzola, Mario;
- Rogliani, Paola;
- Barnes, Peter J.;
- Blasi, Francesco;
- Celli, Bartolome;
- Hanania, Nicola A.;
- Martinez, Fernando J.;
- Miller, Bruce E.;
- Miravitlles, Marc;
- Page, Clive P.;
- Tal-Singer, Ruth;
- Matera, Maria Gabriella
Publication type:
Article
Development of a Blood-based Transcriptional Risk Score for Chronic Obstructive Pulmonary Disease.
Published in:
2022
By:
- Moll, Matthew;
- Boueiz, Adel;
- Ghosh, Auyon J.;
- Saferali, Aabida;
- Sool Lee;
- Zhonghui Xu;
- Yun, Jeong H.;
- Hobbs, Brian D.;
- Hersh, Craig P.;
- Sin, Don D.;
- Tal-Singer, Ruth;
- Silverman, Edwin K.;
- Cho, Michael H.;
- Castaldi, Peter J.;
- Ghosh, Auyon;
- Lee, Sool;
- Xu, Zhonghui;
- HAPIN Investigators
Publication type:
journal article
Supplementary Appendix to "Development of A Blood-Based Transcriptional Risk Score for Chronic Obstructive Pulmonary Disease".
Published in:
American Journal of Respiratory & Critical Care Medicine, 2022, v. 205, n. 2, p. E1, doi. 10.1164/rccm.202107-1584oc
By:
- Moll, Matthew;
- Boueiz, Adel;
- Ghosh, Auyon;
- Saferali, Aabida;
- Sool Lee;
- Zhonghui Xu;
- Yun, Jeong H.;
- Hobbs, Brian D.;
- Hersh, Craig P.;
- Sin, Don D.;
- Tal-Singer, Ruth;
- Silverman, Edwin K.;
- Cho, Michael H.;
- Castaldi, Peter J.
Publication type:
Article
Inflammatory Endotype-associated Airway Microbiome in Chronic Obstructive Pulmonary Disease Clinical Stability and Exacerbations: A Multicohort Longitudinal Analysis.
Published in:
2021
By:
- Zhang Wang;
- Locantore, Nicholas;
- Haldar, Koirobi;
- Ramsheh, Mohammadali Yavari;
- Beech, Augusta S.;
- Wei Ma;
- Brown, James R.;
- Tal-Singer, Ruth;
- Barer, Michael R.;
- Bafadhel, Mona;
- Donaldson, Gavin C.;
- Wedzicha, Jadwiga A.;
- Singh, Dave;
- Wilkinson, Tom M. A.;
- Miller, Bruce E.;
- Brightling, Christopher E.;
- Wang, Zhang;
- Ma, Wei
Publication type:
journal article
Blood Eosinophil Counts in Clinical Trials for Chronic Obstructive Pulmonary Disease.
Published in:
2020
By:
- Singh, Dave;
- Bafadhel, Mona;
- Brightling, Christopher E.;
- Sciurba, Frank C.;
- Curtis, Jeffrey L.;
- Martinez, Fernando J.;
- Pasquale, Cara B.;
- Merrill, Debora D.;
- Metzdorf, Norbert;
- Petruzzelli, Stefano;
- Tal-Singer, Ruth;
- Compton, Christopher;
- Rennard, Stephen;
- Martin, Ubaldo J.;
- COPD Foundation Eosinophil Working Group
Publication type:
journal article
Managing Your Chronic Lung Disease During the COVID-19 Pandemic.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2020, v. 202, n. 2, p. 1, doi. 10.1164/rccm.2020c8
By:
- Sockrider, Marianna;
- Tal-Singer, Ruth
Publication type:
Article
Clinical Development and Research Applications of the Chronic Obstructive Pulmonary Disease Assessment Test.
Published in:
2020
By:
- Müllerová, Hana;
- Dransfield, Mark T.;
- Thomashow, Byron;
- Jones, Paul W.;
- Rennard, Stephen;
- Karlsson, Niklas;
- Fageras, Malin;
- Metzdorf, Norbert;
- Petruzzelli, Stefano;
- Rommes, Jean;
- Sciurba, Frank C.;
- Tabberer, Maggie;
- Merrill, Debora;
- Tal-Singer, Ruth
Publication type:
journal article
DNA Methylation Is Predictive of Mortality in Current and Former Smokers.
Published in:
2020
By:
- Morrow, Jarrett D.;
- Make, Barry;
- Regan, Elizabeth;
- Han, MeiLan;
- Hersh, Craig P.;
- Tal-Singer, Ruth;
- Quackenbush, John;
- Choi, Augustine M. K.;
- Silverman, Edwin K.;
- DeMeo, Dawn L.
Publication type:
journal article
The 6-Minute-Walk Distance Test as a Chronic Obstructive Pulmonary Disease Stratification Tool. Insights from the COPD Biomarker Qualification Consortium.
Published in:
2016
By:
- Celli, Bartolome;
- Tetzlaff, Kay;
- Criner, Gerard;
- Polkey, Michael I.;
- Sciurba, Frank;
- Casaburi, Richard;
- Tal-Singer, Ruth;
- Kawata, Ariane;
- Merrill, Debora;
- Rennard, Stephen;
- COPD Biomarker Qualification Consortium
Publication type:
journal article
Network Analysis of Lung Transcriptomics Reveals a Distinct B-Cell Signature in Emphysema.
Published in:
2016
By:
- Faner, Rosa;
- Cruz, Tamara;
- Casserras, Teresa;
- López-Giraldo, Alejandra;
- Noell, Guillaume;
- Coca, Ignacio;
- Tal-Singer, Ruth;
- Miller, Bruce;
- Rodriguez-Roisin, Roberto;
- Spira, Avrum;
- Kalko, Susana G.;
- Agustí, Alvar
Publication type:
journal article
Plasma Fibrinogen Qualification as a Drug Development Tool in Chronic Obstructive Pulmonary Disease. Perspective of the Chronic Obstructive Pulmonary Disease Biomarker Qualification Consortium.
Published in:
2016
By:
- Miller, Bruce E.;
- Tal-Singer, Ruth;
- Rennard, Stephen I.;
- Furtwaengler, Armin;
- Leidy, Nancy;
- Lowings, Michael;
- Martin, Ubaldo J.;
- Martin, Thomas R.;
- Merrill, Debora D.;
- Snyder, Jeffrey;
- Walsh, John;
- Mannino, David M.
Publication type:
journal article
Plasma Fibrinogen Qualification as a Drug Development Tool in COPD: Perspective of the COPD Biomarker Qualification Consortium.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2016, v. 193, n. 6, p. 1, doi. 10.1164/rccm.201509-1722pp
By:
- Miller, Bruce E.;
- Tal-Singer, Ruth;
- Rennard, Stephen I.;
- Furtwaengler, Armin;
- Leidy, Nancy;
- Lowings, Michael;
- Martin, Ubaldo J.;
- Martin, Thomas;
- Merrill, Debora D.;
- Snyder, Jeffrey;
- Walsh, John;
- Mannino, David M.
Publication type:
Article
Circulating soluble receptor for advanced glycation end products (sRAGE) as a biomarker of emphysema and the RAGE axis in the lung.
Published in:
2015
By:
- Yonchuk, John G.;
- Silverman, Edwin K.;
- Bowler, Russell P.;
- Agustí, Alvar;
- Lomas, David A.;
- Miller, Bruce E.;
- Tal-Singer, Ruth;
- Mayer, Ruth J.
Publication type:
journal article
A Genome-Wide Association Study of Emphysema and Airway Quantitative Imaging Phenotypes.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2015, v. 192, n. 5, p. 559, doi. 10.1164/rccm.201501-0148OC
By:
- Cho, Michael H.;
- Castaldi, Peter J.;
- Hersh, Craig P.;
- Hobbs, Brian D.;
- Barr, R. Graham;
- Tal-Singer, Ruth;
- Bakke, Per;
- Gulsvik, Amund;
- Estépar, Raú San José;
- Van Beek, Edwin J. R.;
- Coxson, Harvey O.;
- Lynch, David A.;
- Washko, George R.;
- Laird, Nan M.;
- Crapo, James D.;
- Beaty, Terri H.;
- Silverman, Edwin K.
Publication type:
Article
A Genome-wide Association Study of Emphysema and Airway Quantitative Imaging Phenotypes.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2015, v. 192, n. 5, p. E1, doi. 10.1164/rccm.201501-0148oc
By:
- Cho, Michael H.;
- Castaldi, Peter J.;
- Hersh, Craig P.;
- Hobbs, Brian D.;
- Barr, R. Graham;
- Tal-Singer, Ruth;
- Bakke, Per;
- Gulsvik, Amund;
- Estépar, Raúl San José;
- Van Beek, Edwin;
- Coxson, Harvey O.;
- Lynch, David A.;
- Washko, George R.;
- Laird, Nan M.;
- Crapo, James D.;
- Beaty, Terri H.;
- Silverman, Edwin K.
Publication type:
Article
High levels of biomarkers of collagen remodeling are associated with increased mortality in COPD - results from the ECLIPSE study.
Published in:
Respiratory Research, 2016, v. 17, p. 1, doi. 10.1186/s12931-016-0440-6
By:
- Sand, Jannie M. B.;
- Leeming, Diana J.;
- Byrjalsen, Inger;
- Bihlet, Asger R.;
- Lange, Peter;
- Tal-Singer, Ruth;
- Miller, Bruce E.;
- Karsdal, Morten A.;
- Vestbo, Jørgen
Publication type:
Article
COPD association and repeatability of blood biomarkers in the ECLIPSE cohort.
Published in:
Respiratory Research, 2011, v. 12, n. 11, p. 1, doi. 10.1186/1465-9921-12-146
By:
- Dickens, Jennifer A.;
- Miller, Bruce E.;
- Edwards, Lisa D.;
- Silverman, Edwin K.;
- Lomas, David A.;
- Tal-Singer, Ruth
Publication type:
Article
COPD association and repeatability of blood biomarkers in the ECLIPSE cohort.
Published in:
2011
By:
- Dickens, Jennifer A;
- Miller, Bruce E;
- Edwards, Lisa D;
- Silverman, Edwin K;
- Lomas, David A;
- Tal-Singer, Ruth;
- Evaluation of COPD Longitudinally to Identify Surrogate Endpoints (ECLIPSE) study investigators
Publication type:
journal article
Characterisation of COPD heterogeneity in the ECLIPSE cohort.
Published in:
2010
By:
- Agusti, Alvar;
- Calverley, Peter M. A.;
- Celli, Bartolome;
- Coxson, Harvey O.;
- Edwards, Lisa D.;
- Lomas, David A.;
- MacNee, William;
- Miller, Bruce E.;
- Rennard, Steve;
- Silverman, Edwin K.;
- Tal-Singer, Ruth;
- Wouters, Emiel;
- Yates, Julie C.;
- Vestbo, Jørgen;
- Vestbo, Jørgen;
- Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) investigators
Publication type:
journal article
Sputum neutrophils as a biomarker in COPD:findings from the ECLIPSE study.
Published in:
Respiratory Research, 2010, v. 11, p. 77, doi. 10.1186/1465-9921-11-77
By:
- Singh, Dave;
- Edwards, Lisa;
- Tal-Singer, Ruth;
- Rennard, Stephen
Publication type:
Article
Chronic obstructive pulmonary disease and inhaled steroids alter surfactant protein D (SP-D) levels: a cross-sectional study.
Published in:
Respiratory Research, 2008, v. 9, p. 1, doi. 10.1186/1465-9921-9-13
By:
- Sims, Michael W.;
- Tal-Singer, Ruth M.;
- Kierstein, Sonja;
- Musani, Ali I.;
- Beers, Michael F.;
- Panettieri, Reynold A.;
- Haczku, Angela
Publication type:
Article
Accelerated elastin degradation by age-disease interaction: a common feature in age-related diseases.
Published in:
NPJ Aging, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41514-024-00143-7
By:
- Shek, Naomi;
- Choy, Anna-Maria;
- Lang, Chim C.;
- Miller, Bruce E.;
- Tal-Singer, Ruth;
- Bolton, Charlotte E.;
- Thomson, Neil C.;
- Chalmers, James D.;
- Bown, Matt J.;
- Newby, David E.;
- Khan, Faisel;
- Huang, Jeffrey T. J.
Publication type:
Article
Pharmacokinetics, pharmacodynamics and adverse event profile of GSK2256294, a novel soluble epoxide hydrolase inhibitor.
Published in:
British Journal of Clinical Pharmacology, 2016, v. 81, n. 5, p. 971, doi. 10.1111/bcp.12855
By:
- Lazaar, Aili L.;
- Yang, Lucy;
- Boardley, Rebecca L.;
- Goyal, Navin S.;
- Robertson, Jonathan;
- Baldwin, Sandra J.;
- Newby, David E.;
- Wilkinson, Ian B.;
- Tal‐Singer, Ruth;
- Mayer, Ruth J.;
- Cheriyan, Joseph
Publication type:
Article
SB-656933, a novel CXCR2 selective antagonist, inhibits ex vivo neutrophil activation and ozone-induced airway inflammation in humans.
Published in:
British Journal of Clinical Pharmacology, 2011, v. 72, n. 2, p. 282, doi. 10.1111/j.1365-2125.2011.03968.x
By:
- Lazaar, Aili L.;
- Sweeney, Lisa E.;
- MacDonald, Alexander J.;
- Alexis, Neil E.;
- Chao Chen;
- Tal-Singer, Ruth
Publication type:
Article
The use of plethysmography and oscillometry to compare long-acting bronchodilators in patients with COPD.
Published in:
British Journal of Clinical Pharmacology, 2008, v. 65, n. 2, p. 244, doi. 10.1111/j.1365-2125.2007.03013.x
By:
- Borrill, Zoë L.;
- Houghton, Catherine M.;
- Tal-Singer, Ruth;
- Vessey, S. Rupert;
- Faiferman, Isidore;
- Langley, Stephen J.;
- Singh, Dave
Publication type:
Article
Short physical performance battery as a practical tool to assess mortality risk in chronic obstructive pulmonary disease.
Published in:
Age & Ageing, 2021, v. 50, n. 3, p. 795, doi. 10.1093/ageing/afaa138
By:
- Fermont, Jilles M;
- Mohan, Divya;
- Fisk, Marie;
- Bolton, Charlotte E;
- Macnee, William;
- Cockcroft, John R;
- McEniery, Carmel;
- Fuld, Jonathan;
- Cheriyan, Joseph;
- Tal-Singer, Ruth;
- Müllerova, Hana;
- Wood, Angela M;
- Wilkinson, Ian B;
- Polkey, Michael I;
- consortium, the ERICA
Publication type:
Article
Fluticasone Propionate Protects against Ozone-Induced Airway Inflammation and Modified Immune Cell Activation Markers in Healthy Volunteers.
Published in:
Environmental Health Perspectives, 2008, v. 116, n. 6, p. 799, doi. 10.1289/ehp.10981
By:
- Alexis, Neil E.;
- Lay, John C.;
- Haczku, Angela;
- Gong, Henry;
- Linn, William;
- Hazucha, Milan J.;
- Harris, Brad;
- Tal-Singer, Ruth;
- Peden, David B.
Publication type:
Article
Genetic Association and Risk Scores in a Chronic Obstructive Pulmonary Disease Meta-analysis of 16,707 Subjects.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2017, v. 57, n. 1, p. 35, doi. 10.1165/rcmb.2016-0331OC
By:
- Busch, Robert;
- Hobbs, Brian D.;
- Jin Zhou;
- Castaldi, Peter J.;
- McGeachie, Michael J.;
- Hardin, Megan E.;
- Hawrylkiewicz, Iwona;
- Sliwinski, Pawel;
- Jae-Joon Yim;
- Woo Jin Kim;
- Kim, Deog K.;
- Agusti, Alvar;
- Make, Barry J.;
- Crapo, James D.;
- Calverley, Peter M.;
- Donner, Claudio F.;
- Lomas, David A.;
- Wouters, Emiel F.;
- Vestbo, Jørgen;
- Tal-Singer, Ruth
Publication type:
Article
Common Genetic Variants Associated with Resting Oxygenation in Chronic Obstructive Pulmonary Disease.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2014, v. 51, n. 5, p. 678, doi. 10.1165/rcmb.2014-0135OC
By:
- McDonald, Merry-Lynn N.;
- Cho, Michael H.;
- Sørheim, Inga-Cecilie;
- Lutz, Sharon M.;
- Castaldi, Peter J.;
- Lomas, David A.;
- Coxson, Harvey O.;
- Edwards, Lisa D.;
- MacNee, William;
- Vestbo, Jørgen;
- Yates, Julie C.;
- Agusti, Alvar;
- Calverley, Peter M. A.;
- Celli, Bartolome;
- Crim, Courtney;
- Rennard, Stephen I.;
- Wouters, Emiel F. M.;
- Bakke, Per;
- Tal-Singer, Ruth;
- Miller, Bruce E.
Publication type:
Article
Polymorphisms in Surfactant Protein-D Are Associated with Chronic Obstructive Pulmonary Disease.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2011, v. 44, n. 3, p. 316, doi. 10.1165/rcmb.2009-0360OC
By:
- Foreman, Marilyn G.;
- Xiangyang Kong;
- DeMeo, Dawn L.;
- Pillai, Sreekumar G.;
- Hersh, Craig P.;
- Bakke, Per;
- Gulsvik, Amund;
- Lomas, David A.;
- Litonjua, Augusto A.;
- Shapiro, Steven D.;
- Tal-Singer, Ruth;
- Silverman, Edwin K.
Publication type:
Article
Vascular inflammation and aortic stiffness: potential mechanisms of increased vascular risk in chronic obstructive pulmonary disease.
Published in:
2018
By:
- Fisk, Marie;
- Cheriyan, Joseph;
- Mohan, Divya;
- McEniery, Carmel M.;
- Forman, Julia;
- Cockcroft, John R.;
- Rudd, James H. F.;
- Tal-Singer, Ruth;
- Hopkinson, Nicholas S.;
- Polkey, Michael I.;
- Wilkinson, Ian B.
Publication type:
journal article

Found: 97