The article discusses a review by L. King and colleagues, published in the issue, which summarizes literature on polycyclic aromatic hydrocarbons (PAHs) in alcohol that suggests these chemicals could also play a role in alcohol-induced carcinogensis. Topics include factors that could advance understanding of the roles of specific PAHs and PAH mixtures and questions of interest for public health raised by the presence of known carcinogens in commonly consumed alcoholic beverages.