Results
Title

Corn Silk Induced Cyclooxygenase-2 in Murine Macrophages.

Authors

Kim, Kyung A.; Hyun-Hee Shin; Sang Kyu Choi; Hye-Seon Choi

Abstract

The article examines the induction of cyclooxygenase-2 (COX-2) in murine macrophages by corn silk. The induction was caused by the secretion of PGE2-Expression of COX-2 and was inhibited by pyrolidine dithiocarbamate and increased DNA binding by nuclear factor kappa B. This mechanism indicates that COX-2 induction proceeds also through the nuclear factor kappa B signaling pathway.

Subjects

CYCLOOXYGENASE 2; MACROPHAGES; DITHIOCARBAMATES; NF-kappa B; DNA-binding proteins

Publication

Bioscience, Biotechnology & Biochemistry, 2005, Vol 69, Issue 10, p1848

ISSN

0916-8451

Publication type

Academic Journal

DOI

10.1271/bbb.69.1848