Title: Gold Nanoparticles Inhibited the Receptor Activator of Nuclear Factor-κB Ligand (RANKL)-Induced Osteoclast Formation by Acting as an Antioxidant.
Authors: Ok-Joo Sul; Jin-Chun Kim; Tae-Wook Kyung; Hye-Jin Kim; Youn-Young Kim; Song-Hee Kim; Ji-Soon Kim; Hye-Seon Choi
Abstract: The article discusses a study which investigated the inhibition by gold nanoparticles of the formation of receptor activator of nuclear factor κB ligand (RANKL)-induced osteoclast (OC). It says that the nanoparicles inhibited the production of reactive oxygen species (ROS) and increased antioxidant enzyme level upon bone marrow-derived macrophages (BMMs) stimulation. It notes that gold nanoparicles can diminish bone loss by reducing OC formation.
Subjects: NANOPARTICLES; GOLD; NF-kappa B; OSTEOCLAST inhibition; MACROPHAGES
Publication: Bioscience, Biotechnology & Biochemistry, 2010, Vol 74, Issue 11, p2209
ISSN: 0916-8451
Publication type: Academic Journal
DOI: 10.1271/bbb.100375

Gold Nanoparticles Inhibited the Receptor Activator of Nuclear Factor-κB Ligand (RANKL)-Induced Osteoclast Formation by Acting as an Antioxidant.

Ok-Joo Sul; Jin-Chun Kim; Tae-Wook Kyung; Hye-Jin Kim; Youn-Young Kim; Song-Hee Kim; Ji-Soon Kim; Hye-Seon Choi