Title: Silymarin inhibits melanin synthesis in melanocyte cells.
Authors: Soo-Jin Choo; In-Ja Ryoo; Young-Hee Kim; Guang-Hwa Xu; Won-Gon Kim; Ki-Ho Kim; Seong-Joon Moon; Eui-Dong Son; Kihwan Bae; Ick-Dong Yoo
Abstract: The article presents a study which investigates the effect of silymarin as an inhibitor of melanogenesis. The study includes the identification of the inhibitory effect of silymarin on melanogenesis in mouse melanocytes. Results show that the silymarin reduces the expression of tyrosinase protein and is useful as a skin whitening agent.
Subjects: MELANOGENESIS; MELANOCYTES; SILYMARIN; SKIN disease prevention; PHENOL oxidase; LABORATORY mice
Publication: Journal of Pharmacy & Pharmacology, 2009, Vol 61, Issue 5, p663
ISSN: 0022-3573
Publication type: Academic Journal
DOI: 10.1211/jpp.61.05.0016

Silymarin inhibits melanin synthesis in melanocyte cells.

Soo-Jin Choo; In-Ja Ryoo; Young-Hee Kim; Guang-Hwa Xu; Won-Gon Kim; Ki-Ho Kim; Seong-Joon Moon; Eui-Dong Son; Kihwan Bae; Ick-Dong Yoo