Objective:To construct risk factors assessment table of intensive care unit-acquired weakness, in order to provide basis for the establishment of risk assessment tools for acquired weakness. Methods:Literature review and group discussion were used to screen the risk factors of intensive care unit-acquired weakness, and the risk factors assessment table was formed by Delphi method. Results: There were two rounds of expert consultation. The expert positivity coefficient of 2 rounds of expert letter questionnaires were 100. 00% and 95. 65%. The expert authority coefficients were 0. 91 and 0. 93. And Kendall coordination coefficients were 0. 43 and 0. 49, respectively (P<0. 001). The final constructed risk factors assessment table of intensive care unit-acquired weakness included 7 dimensions with a total of 45 items. The S-CVI was 0. 86. The average score of the dimensions ranged from 4. 28 to 4. 90, and the coefficient of variation ranged from 0. 06 to 0. 18. The average score of item importance ranged from 3. 80 to 5. 00, and the coefficient of variation ranged from 0. 00 to 0. 29. Conclusions:The risk factors assessment table of intensive care unit - acquired weakness was scientific and practical, which can provide tool for the risk identification of acquired frailty in critically ill patients.