Works matching DE "TUMOR suppressor proteins"
Results: 3282
PTEN is a protein tyrosine phosphatase for IRS1.
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- Nature Structural & Molecular Biology, 2014, v. 21, n. 6, p. 522, doi. 10.1038/nsmb.2828
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- Article
PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53.
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- Nature Structural & Molecular Biology, 2012, v. 19, n. 9, p. 916, doi. 10.1038/nsmb.2353
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- Article
A glutamate switch controls voltage-sensitive phosphatase function.
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- Nature Structural & Molecular Biology, 2012, v. 19, n. 6, p. 633, doi. 10.1038/nsmb.2289
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- Article
Structural analysis of the interaction between Hsp90 and the tumor suppressor protein p53.
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- Nature Structural & Molecular Biology, 2011, v. 18, n. 10, p. 1086, doi. 10.1038/nsmb.2114
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- Article
BRCA2 acts as a RAD51 loader to facilitate telomere replication and capping.
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- Nature Structural & Molecular Biology, 2010, v. 17, n. 12, p. 1461, doi. 10.1038/nsmb.1943
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- Article
The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA.
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- Nature Structural & Molecular Biology, 2010, v. 17, n. 10, p. 1263, doi. 10.1038/nsmb.1905
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- Article
Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA.
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- Nature Structural & Molecular Biology, 2010, v. 17, n. 10, p. 1260, doi. 10.1038/nsmb.1904
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- Article
An overlapping kinase and phosphatase docking site regulates activity of the retinoblastoma protein.
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- Nature Structural & Molecular Biology, 2010, v. 17, n. 9, p. 1051, doi. 10.1038/nsmb.1868
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- Article
The C terminus of p53 binds the N-terminal domain of MDM2.
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- Nature Structural & Molecular Biology, 2010, v. 17, n. 8, p. 982, doi. 10.1038/nsmb.1872
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- Article
Research highlights.
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- Nature Structural & Molecular Biology, 2010, v. 17, n. 6, p. 678, doi. 10.1038/nsmb0610-678
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- Article
Four p(53)s in a pod.
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- 2010
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- Publication type:
- Opinion
Cabin1 restrains p53 activity on chromatin.
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- Nature Structural & Molecular Biology, 2009, v. 16, n. 9, p. 910, doi. 10.1038/nsmb.1657
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- Article
Molecular basis of Pirh2-mediated p53 ubiquitylation.
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- Nature Structural & Molecular Biology, 2008, v. 15, n. 12, p. 1334, doi. 10.1038/nsmb.1521
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- Article
When loose ends finally meet.
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- Nature Structural & Molecular Biology, 2008, v. 15, n. 12, p. 1241, doi. 10.1038/nsmb1208-1241
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- Article
Tumor suppressor p53 restricts Ras stimulation of RhoA and cancer cell motility.
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- Nature Structural & Molecular Biology, 2007, v. 14, n. 3, p. 215, doi. 10.1038/nsmb1208
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- Article
Research highlights.
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- Nature Structural & Molecular Biology, 2007, v. 14, n. 2, p. 102, doi. 10.1038/nsmb0207-102
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- Article
The vertebrate Hef ortholog is a component of the Fanconi anemia tumor-suppressor pathway.
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- Nature Structural & Molecular Biology, 2005, v. 12, n. 9, p. 763, doi. 10.1038/nsmb981
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- Article
The tumor suppressor p16<sup>INK4a</sup> prevents cell transformation through inhibition of c-Jun phosphorylation and AP-1 activity.
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- Nature Structural & Molecular Biology, 2005, v. 12, n. 8, p. 699, doi. 10.1038/nsmb960
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- Article
Mediating repair.
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- Nature Structural & Molecular Biology, 2005, v. 12, n. 3, p. 213, doi. 10.1038/nsmb0305-213
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- Article
Hey1- and p53-dependent TrkC proapoptotic activity controls neuroblastoma growth.
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- PLoS Biology, 2018, v. 16, n. 5, p. 1, doi. 10.1371/journal.pbio.2002912
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- Article
The phosphorylation status of merlin in sporadic vestibular Schwannomas.
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- Molecular & Cellular Biochemistry, 2009, v. 324, n. 1/2, p. 201, doi. 10.1007/s11010-008-0014-0
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- Article
Prohibitin suppresses renal interstitial fibroblasts proliferation and phenotypic change induced by transforming growth factor-β1.
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- Molecular & Cellular Biochemistry, 2007, v. 295, n. 1, p. 167, doi. 10.1007/s11010-006-9286-4
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- Article
Molecular dynamics simulation of S100B protein to explore ligand blockage of the interaction with p53 protein.
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- Journal of Computer-Aided Molecular Design, 2009, v. 23, n. 10, p. 705, doi. 10.1007/s10822-009-9294-z
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- Article
From modulation of cellular plasticity to potentiation of therapeutic resistance: new and emerging roles of MYB transcription factors in human malignancies.
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- Cancer & Metastasis Reviews, 2024, v. 43, n. 1, p. 409, doi. 10.1007/s10555-023-10153-8
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- Article
Caveolin-1 function at the plasma membrane and in intracellular compartments in cancer.
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- Cancer & Metastasis Reviews, 2020, v. 39, n. 2, p. 435, doi. 10.1007/s10555-020-09890-x
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- Article
KISS1 in breast cancer progression and autophagy.
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- Cancer & Metastasis Reviews, 2019, v. 38, n. 3, p. 493, doi. 10.1007/s10555-019-09814-4
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- Article
Functions of the APC tumor suppressor protein dependent and independent of canonical WNT signaling: implications for therapeutic targeting.
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- Cancer & Metastasis Reviews, 2018, v. 37, n. 1, p. 159, doi. 10.1007/s10555-017-9725-6
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- Article
E3 ubiquitin ligases in cancer and implications for therapies.
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- Cancer & Metastasis Reviews, 2017, v. 36, n. 4, p. 683, doi. 10.1007/s10555-017-9703-z
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- Article
Ubiquitin carboxyl-terminal hydrolases: involvement in cancer progression and clinical implications.
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- Cancer & Metastasis Reviews, 2017, v. 36, n. 4, p. 669, doi. 10.1007/s10555-017-9702-0
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- Article
The role of deubiquitinases in breast cancer.
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- Cancer & Metastasis Reviews, 2016, v. 35, n. 4, p. 589, doi. 10.1007/s10555-016-9640-2
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- Article
p53 expression status is a significant molecular marker in predicting the time to endocrine therapy failure in recurrent breast cancer: a cohort study.
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- International Journal of Clinical Oncology, 2006, v. 11, n. 6, p. 426, doi. 10.1007/s10147-006-0601-6
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- Article
Recent advances in ideas on the molecular pathology and clinical aspects of Von Hippel-Lindau disease.
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- International Journal of Clinical Oncology, 2004, v. 9, n. 4, p. 283, doi. 10.1007/s10147-004-0415-3
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- Article
PTEN expression in endometrial hyperplasia and risk of cancer: a systematic review and meta-analysis.
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- 2019
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- Publication type:
- journal article
Expression and methylation status of the Syk gene in cervical carcinoma.
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- 2011
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- Publication type:
- journal article
Role of cdk4, p16, and Rb Expression in the Prognosis of Bronchioloalveolar Carcinomas.
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- Respiration, 2005, v. 72, n. 1, p. 68, doi. 10.1159/000083403
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- Article
Improving survival by exploiting tumour dependence on stabilized mutant p53 for treatment.
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- Nature, 2015, v. 523, n. 7560, p. 352, doi. 10.1038/nature14430
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- Article
Cancer: Precise control of localized signals.
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- Nature, 2015, v. 522, n. 7554, p. 38, doi. 10.1038/nature14531
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- Article
IAPP-driven metabolic reprogramming induces regression of p53-deficient tumours in vivo.
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- Nature, 2015, v. 517, n. 7536, p. 626, doi. 10.1038/nature13910
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- Article
Mechanism of Dis3l2 substrate recognition in the Lin28-let-7 pathway.
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- Nature, 2014, v. 514, n. 7521, p. 252, doi. 10.1038/nature13553
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- Article
Fructose-1,6-bisphosphatase opposes renal carcinoma progression.
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- Nature, 2014, v. 513, n. 7517, p. 251, doi. 10.1038/nature13557
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- Article
Metastasis-suppressor transcript destabilization through TARBP2 binding of mRNA hairpins.
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- Nature, 2014, v. 513, n. 7517, p. 256, doi. 10.1038/nature13466
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- Article
Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy.
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- Nature, 2014, v. 508, n. 7495, p. 222, doi. 10.1038/nature13194
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- Article
MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool.
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- Nature, 2014, v. 508, n. 7495, p. 215, doi. 10.1038/nature13181
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- Article
ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression.
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- Nature, 2014, v. 508, n. 7495, p. 263, doi. 10.1038/nature13045
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- Article
Cancer: Switching p53 back on.
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- Nature, 2012, v. 485, n. 7400, p. 550, doi. 10.1038/485550b
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- Article
Modulation of immune responses by the tumor suppressor p53.
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- BioDiscovery, 2017, p. 1, doi. 10.7750/BioDiscovery.2013.8.2
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- Article
Concomitant loss of TET2 and TET3 results in T cell expansion and genomic instability in mice.
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- Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07312-0
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- Article
Erratum: TET1 is a tumor suppressor of hematopoietic malignancy.
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- Nature Immunology, 2015, v. 16, n. 8, p. 889, doi. 10.1038/ni0815-889a
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- Article
Corrigendum: The kinase Jnk2 promotes stress-induced mitophagy by targeting the small mitochondrial form of the tumor suppressor ARF for degradation.
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- Nature Immunology, 2015, v. 16, n. 7, p. 785, doi. 10.1038/ni0715-785b
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- Article
A 'Tsc, Tsc' keeps the kids quie(scen)t and holds down ROS.
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- Nature Immunology, 2011, v. 12, n. 9, p. 811, doi. 10.1038/ni.2092
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- Article