Results
Title

Prepregnancy and Gestational Interventions to Prevent Childhood Obesity.

Authors

Kampmann, Ulla; Suder, Louise Birk; Nygaard, Malene; Geiker, Nina Rica Wium; Nielsen, Henriette Svarre; Almstrup, Kristian; Bruun, Jens Meldgaard; Magkos, Faidon; Ovesen, Per; Catalano, Patrick

Abstract

Childhood obesity is a significant global health issue with complex and multifactorial origins, often beginning before conception and influenced by both maternal and paternal health. The increased prevalence of prepregnancy obesity and gestational diabetes mellitus in women of reproductive age contributes to a heightened risk of metabolic dysfunction in offspring. Current clinical practices often implement lifestyle interventions after the first trimester and have limited success, implying that they miss a critical window for effective metabolic adjustments. This review examines the limitations of lifestyle interventions during pregnancy in improving perinatal outcomes and highlights the importance of initiating such interventions before conception to positively impact parental health and fetal development. A re-evaluation of strategies is needed to enhance the metabolic health of prospective parents as a preventive measure against childhood obesity.

Subjects

CHILDBEARING age; METABOLIC disorders; FETAL development; WORLD health; MATERNAL health; GESTATIONAL diabetes; CHILDHOOD obesity

Publication

Journal of Clinical Endocrinology & Metabolism, 2025, Vol 110, Issue 1, pe8

ISSN

0021-972X

Publication type

Academic Journal

DOI

10.1210/clinem/dgae724