Works matching AU Walker, Brian R.

Results: 139

How will we know if 11b.hydroxysteroid dehydrogenases are important in common diseases*.

Published in:

Clinical Endocrinology, 2000, v. 52, n. 4, p. 401, doi. 10.1046/j.1365-2265.2000.00969.x

By:

Walker, Brian R.;
Walker, Brian R

Publication type:

Article

Growth hormone replacement inhibits renal and hepatic 11β–hydroxysteroid dehydrogenases in ACTH-deficient patients.

Published in:

Clinical Endocrinology, 1998, v. 49, n. 2, p. 257, doi. 10.1046/j.1365-2265.1998.00575.x

By:

Walker, Brian R;
Andrew, Ruth;
MacLeod, Kenneth M;
Padfield, Paul L;
R Walker, Brian

Publication type:

Article

Effect of Synthetic Corticosteroids on Vascular Reactivity in the Human Forearm*.

Published in:

Clinical & Experimental Hypertension, 2006, v. 28, n. 8, p. 707, doi. 10.1080/10641960601013674

By:

Mangos, George J.;
Walker, Brian R.;
Williamson, Paula A.;
Whitworth, Judith A.;
Kelly, John J.

Publication type:

Article

Identification of human glucocorticoid response markers using integrated multi- omic analysis from a randomized crossover trial.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.62236

By:

Chantzichristos, Dimitrios;
Svensson, Per-Arne;
Garner, Terence;
Glad, Camilla A. M.;
Walker, Brian R.;
Bergthorsdottir, Ragnhildur;
Ragnarsson, Oskar;
Trimpou, Penelope;
Stimson, Roland H.;
Borresen, Stina W.;
Feldt-Rasmussen, Ulla;
Jansson, Per-Anders;
Skrtic, Stanko;
Stevens, Adam;
Johannsson, Gudmundur

Publication type:

Article

Visceral and subcutaneous fat have different origins and evidence supports a mesothelial source.

Published in:

Nature Cell Biology, 2014, v. 16, n. 4, p. 367, doi. 10.1038/ncb2922

By:

Chau, You-Ying;
Bandiera, Roberto;
Serrels, Alan;
Martínez-Estrada, Ofelia M.;
Qing, Wei;
Lee, Martin;
Slight, Joan;
Thornburn, Anna;
Berry, Rachel;
McHaffie, Sophie;
Stimson, Roland H.;
Walker, Brian R.;
Chapuli, Ramon Muñoz;
Schedl, Andreas;
Hastie, Nick

Publication type:

Article

Plasma cortisol-linked gene networks in hepatic and adipose tissues implicate corticosteroidbinding globulin in modulating tissue glucocorticoid action and cardiovascular risk.

Published in:

Frontiers in Endocrinology, 2023, p. 1, doi. 10.3389/fendo.2023.1186252

By:

Bankier, Sean;
Lingfei Wang;
Crawford, Andrew;
Morgan, Ruth A.;
Ruusalepp, Arno;
Andrew, Ruth;
Björkegren, Johan L. M.;
Walker, Brian R.;
Michoel, Tom

Publication type:

Article

The role and regulation of 11β-hydroxysteroid dehydrogenase type 1 in obesity and the metabolic syndrome.

Published in:

Hormone Molecular Biology & Clinical Investigation, 2013, v. 15, n. 2, p. 37, doi. 10.1515/hmbci-2013-0015

By:

Stimson, Roland H.;
Walker, Brian R.

Publication type:

Article

Taking Glucocorticoids by Prescription Is Associated with Subsequent Cardiovascular Disease.

Published in:

Annals of Internal Medicine, 2004, v. 141, n. 10, p. 764, doi. 10.7326/0003-4819-141-10-200411160-00007

By:

Li Wei;
MacDonald, Thomas M.;
Walker, Brian R.

Publication type:

Article

ECAT-V: where clinical and research training meet.

Published in:

Veterinary Record: Journal of the British Veterinary Association, 2013, v. 173, n. 15, p. 364, doi. 10.1136/vr.f6185

By:

Argyle, David J.;
Iredale, John P.;
Jackson, Andrew P.;
Walker, Brian R.

Publication type:

Article

LETTERS TO THE EDITOR Glycosylated Hemoglobin Levels in Healthy Elderly Nondiabetic Men are Negatively Associated with Verbal Memory.

Published in:

2004

By:

MacLullich, Alasdair M. J.;
Deary, Ian J.;
Walker, Brian R.;
Seckl, Jonathan R.

Publication type:

Letter

Clinical investigation of 11β-hydroxysteroid dehydrogenase.

Published in:

Endocrine Research, 1995, v. 21, n. 1/2, p. 379, doi. 10.3109/07435809509030454

By:

Walker, Brian R;
Best, Ruth

Publication type:

Article

Corticotroph isolation from Pomc‐eGFP mice reveals sustained transcriptional dysregulation characterising a mouse model of glucocorticoid‐induced suppression of the hypothalamus–pituitary–adrenal axis.

Published in:

Journal of Neuroendocrinology, 2022, v. 34, n. 7, p. 1, doi. 10.1111/jne.13165

By:

Duncan, Peter J.;
McClafferty, Heather;
Nolan, Oscar;
Ding, Qinghui;
Homer, Natalie Z. M.;
Le Tissier, Paul;
Walker, Brian R.;
Shipston, Michael J.;
Romanò, Nicola;
Chambers, Thomas J. G.

Publication type:

Article

The NE/AAT/CBG axis regulates adipose tissue glucocorticoid exposure.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-024-55693-x

By:

Boyle, Luke D.;
Miguelez-Crespo, Allende;
Paul, Mhairi;
Villalobos, Elisa;
Toews, Julia N. C.;
Ivatt, Lisa;
Nagy, Boglarka;
Magennis, Marisa;
Homer, Natalie Z. M.;
Andrew, Ruth;
Viau, Victor;
Hammond, Geoffrey L.;
Stimson, Roland H.;
Walker, Brian R.;
Nixon, Mark

Publication type:

Article

Vascular Dysfunction in Horses with Endocrinopathic Laminitis.

Published in:

PLoS ONE, 2016, v. 11, n. 9, p. 1, doi. 10.1371/journal.pone.0163815

By:

Morgan, Ruth A.;
Keen, John A.;
Walker, Brian R.;
Hadoke, Patrick W. F.

Publication type:

Article

Tissue-specific dysregulation of 11β-hydroxysteroid dehydrogenase type 1 in overweight/obese women with polycystic ovary syndrome compared with weight-matched controls.

Published in:

European Journal of Endocrinology, 2014, v. 171, n. 1, p. 47, doi. 10.1530/EJE-13-1030

By:

Gambineri, Alessandra;
Fanelli, Flaminia;
Tomassoni, Federica;
Munarini, Alessandra;
Pagotto, Uberto;
Andrew, Ruth;
Walker, Brian R.;
Pasquali, Renato

Publication type:

Article

Individual multi-locus heterozygosity is associated with lower morning plasma cortisol concentrations.

Published in:

European Journal of Endocrinology, 2013, v. 169, n. 1, p. 59, doi. 10.1530/EJE-12-0916

By:

Zgaga, Lina;
Vitart, Veronique;
Hayward, Caroline;
Kastelan, Darko;
Polašek, Ozren;
Jakovljevic, Miro;
Kolcic, Ivana;
Biloglav, Zrinka;
Wright, Alan F.;
Campbell, Harry;
Walker, Brian R.;
Rudan, Igor

Publication type:

Article

Quality of life in adults with congenital adrenal hyperplasia relates to glucocorticoid treatment, adiposity and insulin resistance: United Kingdom Congenital adrenal Hyperplasia Adult Study Executive (CaHASE).

Published in:

European Journal of Endocrinology, 2013, v. 168, n. 6, p. 887, doi. 10.1530/EJE-13-0128

By:

Thang S. Han;
Krone, Nils;
Willis, Debbie S.;
Conway, Gerard S.;
Hahner, Stefanie;
Rees, D. Aled;
Stimson, Roland H.;
Walker, Brian R.;
Arlt, Wiebke;
Ross, Richard J.

Publication type:

Article

Glucocorticoid treatment and impaired mood, memory and metabolism in people with diabetes: the Edinburgh Type 2 Diabetes Study.

Published in:

European Journal of Endocrinology, 2012, v. 166, n. 5, p. 861

By:

Reynolds, Rebecca M.;
Labad, Javier;
Sears, Alison V.;
Williamson, Rachel M.;
Strachan, Mark W. J.;
Deary, Ian J;
Lowe, Gordon D. O.;
Price, Jackie F.;
Walker, Brian R.

Publication type:

Article

A combination of polymorphisms in HSD11B1 associates with in vivo 11&BETA;-HSD1 activity and metabolic syndrome in women with and without polycystic ovary syndrome.

Published in:

European Journal of Endocrinology, 2011, v. 165, n. 2, p. 283, doi. 10.1530/EJE-11-0091

By:

Gambineri, Alessandra;
Tomassoni, Federica;
Munarini, Alessandra;
Stimson, Roland H.;
Mioni, Roberto;
Pagotto, Uberto;
Chapman, Karen E.;
Andrew, Ruth;
Mantovani, Vilma;
Pasquali, Renato;
Walker, Brian R.

Publication type:

Article

Glucocorticoids and Cardiovascular Disease.

Published in:

European Journal of Endocrinology, 2007, v. 157, n. 5, p. 545, doi. 10.1530/EJE-07-0455

By:

Brian R Walker

Publication type:

Article

Is there a gender difference in the associations of birthweight and adult hypothalamicpituitaryadrenal axis activity?

Published in:

European Journal of Endocrinology, 2005, v. 152, n. 2, p. 249, doi. 10.1530/eje.1.01846

By:

Rebecca M Reynolds;
Brian R Walker;
Holly E Syddall;
Ruth Andrew;
Peter J Wood;
David I W Phillips

Publication type:

Article

Is programming of glucocorticoid receptor expression by prenatal dexamethasone in the rat secondary to metabolic derangement in adulthood?

Published in:

European Journal of Endocrinology, 2003, v. 148, n. 1, p. 129, doi. 10.1530/eje.0.1480129

By:

Cleasby, Mark E.;
Livingstone, Dawn E. W.;
Nyirenda, Moffat J.;
Seckl, Jonathan R.;
Walker, Brian R.

Publication type:

Article

Effects of Obesity and Insulin on Tissue-Specific Recycling Between Cortisol and Cortisone in Men.

Published in:

2021

By:

Anderson, Anna J.;
Andrew, Ruth;
Homer, Natalie Z. M.;
Hughes, Katherine A.;
Boyle, Luke D.;
Nixon, Mark;
Karpe, Fredrik;
Stimson, Roland H.;
Walker, Brian R.

Publication type:

journal article

Morning Cortisol Levels and Cognitive Abilities in People With Type 2 Diabetes.

Published in:

Diabetes Care, 2010, v. 33, n. 4, p. 714, doi. 10.2337/dc09-1796

By:

Reynolds, Rebecca M.;
Strachan, Mark W. J.;
Labad, Javier;
Lee, Amanda J.;
Frier, Brian M.;
Fowkes, F. Gerald;
Mitchell, Rory;
Seckl, Jonathan R.;
Deary, Ian J.;
Walker, Brian R.;
Price, Jackie F.

Publication type:

Article

Insulin Response in Relation to Insulin Sensitivity.

Published in:

Diabetes Care, 2009, v. 32, n. 5, p. 860, doi. 10.2337/dc08-2048

By:

Goedecke, Julia H.;
Dave, Joel A.;
Faulenbach, Mirjam V.;
Utzschneider, Kristina M.;
Lambert, Estelle V.;
West, Sacha;
Collins, Malcolm;
Olsson, Tommy;
Walker, Brian R.;
Seckl, Jonathan R.;
Kahn, Steven E.;
Levitt, Naomi S.

Publication type:

Article

Memory deficits in a juvenile rat model of type 1 diabetes are due to excess 11β-HSD1 activity, which is upregulated by high glucose concentrations rather than insulin deficiency.

Published in:

Diabetologia, 2023, v. 66, n. 9, p. 1735, doi. 10.1007/s00125-023-05942-3

By:

Brossaud, Julie;
Bosch-Bouju, Clémentine;
Marissal-Arvy, Nathalie;
Campas-Lebecque, Marie-Neige;
Helbling, Jean-Christophe;
Webster, Scott P.;
Walker, Brian R.;
Fioramonti, Xavier;
Ferreira, Guillaume;
Barat, Pascal;
Corcuff, Jean-Benoît;
Moisan, Marie-Pierre

Publication type:

Article

Evaluation of an FFQ to assess total energy and nutrient intakes in severely obese pregnant women.

Published in:

Public Health Nutrition, 2013, v. 16, n. 8, p. 1427, doi. 10.1017/S136898001200417X

By:

Mohd-Shukri, Nor A;
Bolton, Jennifer L;
Norman, Jane E;
Walker, Brian R;
Reynolds, Rebecca M

Publication type:

Article

Exploring the Temporal Relation between Body Mass Index and Corticosteroid Metabolite Excretion in Childhood.

Published in:

Nutrients, 2020, v. 12, n. 5, p. 1525, doi. 10.3390/nu12051525

By:

Van Keulen, Britt J.;
Dolan, Conor V.;
Andrew, Ruth;
Walker, Brian R.;
Hulshoff Pol, Hilleke E.;
Boomsma, Dorret I.;
Rotteveel, Joost;
Finken, Martijn J.J.

Publication type:

Article

Health Behaviours during Pregnancy in Women with Very Severe Obesity.

Published in:

Nutrients, 2015, v. 7, n. 10, p. 8431, doi. 10.3390/nu7105403

By:

Mohd-Shukri, Nor A.;
Duncan, Andrew;
Denison, Fiona C.;
Forbes, Shareen;
Walker, Brian R.;
Norman, Jane E.;
Reynolds, Rebecca M.

Publication type:

Article

Skeletal muscle glucocorticoid receptor density and insulin resistance.

Published in:

2002

By:

Reynolds, Rebecca M;
Chapman, Karen E;
Seckl, Jonathan R;
Walker, Brian R;
McKeigue, Paul M;
Lithell, Hans O

Publication type:

Letter

Letters.

Published in:

2002

By:

Caspi, Opher;
Golomb, Beatrice;
Keeley, Robert;
Barsky, Arthur J.;
Rogers, Malcolm P.;
Borus, Jonathan F.;
Catlin, Elizabeth A.;
Todres, I. David;
Horlen, Cheryl;
Malone, Robb;
Bryant, Betsy;
Dennis, Betty;
Carey, Tim;
Pignone, Mike;
Rothman, Russell;
Reynolds, Rebecca M.;
Chapman, Karen E.;
Seckl, Jonathan R.;
Walker, Brian R.;
McKeigue, Paul M.

Publication type:

Letter

Estrogens and Glucocorticoids in Mammary Adipose Tissue: Relationships with Body Mass Index and Breast Cancer Features.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2020, v. 105, n. 4, p. e1504, doi. 10.1210/clinem/dgz268

By:

Laforest, Sofia;
Pelletier, Mélissa;
Denver, Nina;
Poirier, Brigitte;
Nguyen, Sébastien;
Walker, Brian R.;
Durocher, Francine;
Homer, Natalie Z.M.;
Diorio, Caroline;
Andrew, Ruth;
Tchernof, André

Publication type:

Article

GDF15 Is Elevated in Conditions of Glucocorticoid Deficiency and Is Modulated by Glucocorticoid Replacement.

Published in:

2019

By:

Melvin, Audrey;
Chantzichristos, Dimitrios;
Kyle, Catriona J;
Mackenzie, Scott D;
Walker, Brian R;
Johannsson, Gudmundur;
Stimson, Roland H;
O'Rahilly, Stephen

Publication type:

journal article

Estrogens and Glucocorticoids in Mammary Adipose Tissue: Relationships with Body Mass Index and Breast Cancer Features.

Published in:

2019

By:

Laforest, Sofia;
Pelletier, Mélissa;
Denver, Nina;
Poirier, Brigitte;
Nguyen, Sébastien;
Walker, Brian R;
Durocher, Francine;
Homer, Natalie Z M;
Diorio, Caroline;
Andrew, Ruth;
Tchernof, André

Publication type:

journal article

Heritability of Cortisol Production and Metabolism Throughout Adolescence.

Published in:

2019

By:

van Keulen, Britt J;
Dolan, Conor V;
Andrew, Ruth;
Walker, Brian R;
Hulshoff Pol, Hilleke E;
Boomsma, Dorret I;
Rotteveel, Joost;
Finken, Martijn J J

Publication type:

journal article

Higher Insulin Resistance and Adiposity in Postmenopausal Women With Breast Cancer Treated With Aromatase Inhibitors.

Published in:

2019

By:

Gibb, Fraser W;
Dixon, J Michael;
Clarke, Catriona;
Homer, Natalie Z;
Faqehi, Abdullah M M;
Andrew, Ruth;
Walker, Brian R

Publication type:

journal article

Differential Effects of Abdominal Adipose Tissue Distribution on Insulin Sensitivity in Black and White South African Women.

Published in:

Obesity (19307381), 2009, v. 17, n. 8, p. 1506, doi. 10.1038/oby.2009.73

By:

Goedecke, Julia H.;
Levitt, Naomi S.;
Lambert, Estelle V.;
Utzschneider, Kristina M.;
Faulenbach, Mirjam V.;
Dave, Joel A.;
West, Sacha;
Victor, Hendriena;
Evans, Juliet;
Olsson, Tommy;
Walker, Brian R.;
Seckl, Jonathan R.;
Kahn, Steven E.

Publication type:

Article

Omental 11ß-hydroxysteroid Dehydrogenase 1 Correlates with Fat Cell Size Independently of Obesity.

Published in:

Obesity (19307381), 2007, v. 15, n. 5, p. 1155, doi. 10.1038/oby.2007.618

By:

Michailidou, Zoi;
Jensen, Michael D.;
Dumesic, Daniel A.;
Chapman, Karen E.;
Seckl, Jonathan R.;
Walker, Brian R.;
Morton, Nicholas M.

Publication type:

Article

11β-Hydroxysteroid Dehydrogenase Type 1 in Adipose Tissue and Prospective Changes in Body Weight and Insulin Resistance<sup>*</sup>.

Published in:

Obesity (19307381), 2006, v. 14, n. 9, p. 1515, doi. 10.1038/oby.2006.175

By:

Koska, Juraj;
de Courten, Barbora;
Wake, Deborah J.;
Nair, Saraswathy;
Walker, Brian R.;
Bunt, Joy C.;
Permana, Paska A.;
Lindsay, Robert S.;
Tataranni, P. Antonio

Publication type:

Article

Increased A-ring Reduction of Glucocorticoids in Obese Zucker Rats: Effects of Insulin Sensitization<sup>**</sup>.

Published in:

Obesity (19307381), 2005, v. 13, n. 9, p. 1523, doi. 10.1038/oby.2005.186

By:

Livingstone, Dawn E.W.;
McInnes, Kerry J.;
Walker, Brian R.;
Andrew, Ruth

Publication type:

Article

11β-Hydroxysteroid Dehydrogenase Type 1 in Obesity.

Published in:

Obesity (19307381), 2004, v. 12, n. 1, p. 1, doi. 10.1038/oby.2004.1

By:

Walker, Brian R.

Publication type:

Article

Therapeutic manipulation of glucocorticoid metabolism in cardiovascular disease.

Published in:

2009

By:

Hadoke, Patrick W. F.;
Iqbal, Javaid;
Walker, Brian R.

Publication type:

journal article

β-Cell-specific glucocorticoid reactivation attenuates inflammatory β-cell destruction.

Published in:

Frontiers in Endocrinology, 2014, v. 5, p. 1, doi. 10.3389/fendo.2014.00165

By:

Xiaoxia Liu;
Turban, Sophie;
Carter, Roderick N.;
Ahmad, Shakil;
Ramage, Lynne;
Webster, Scott P.;
Walker, Brian R.;
Seckl, Jonathan R.;
Morton, Nicholas M.

Publication type:

Article

Improved heart function follows enhanced inflammatory cell recruitment and angiogenesis in 11βHSD1-deficient mice post-MI.

Published in:

Cardiovascular Research, 2010, v. 88, n. 1, p. 159, doi. 10.1093/cvr/cvq149

By:

McSweeney, Sara J.;
Hadoke, Patrick W. F.;
Kozak, Agnieszka M.;
Small, Gary R.;
Khaled, Hiba;
Walker, Brian R.;
Gray, Gillian A.

Publication type:

Article

Reply to Letter to the Editor.

Published in:

2002

By:

Walker, Brian R.;
Shore, Angela C.

Publication type:

Letter

Impairment of forearm vasodilatation to acetylcholine in hypercholesterolemia is reversed by aspirin.

Published in:

Cardiovascular Research, 1998, v. 38, n. 2, p. 480, doi. 10.1016/S0008-6363(98)00013-3

By:

Noon, Joseph P;
Walker, Brian R;
Hand, Malcolm F;
Webb, David J

Publication type:

Article

Extra-adrenal regeneration of glucocorticoids by 11β-hydroxysteroid dehydrogenase type 1: physiological regulator and pharmacological target for energy partitioning.

Published in:

Proceedings of the Nutrition Society, 2007, v. 66, n. 1, p. 1, doi. 10.1017/S002966510700523X

By:

Walker, Brian R.

Publication type:

Article

Proof of concept for a superior therapeutic index of corticosterone compared with hydrocortisone in patients with congenital adrenal hyperplasia.

Published in:

European Journal of Endocrinology, 2024, v. 191, n. 6, p. 535, doi. 10.1093/ejendo/lvae144

By:

Kyle, Catriona J;
Boyle, Luke D;
Nixon, Mark;
Homer, Natalie Z M;
Simpson, Joanna P;
Rutter, Alison;
Ramage, Lynne E;
Kelman, Alexandra;
Freel, Ellen Marie;
Andrew, Ruth;
Walker, Brian R;
Stimson, Roland H

Publication type:

Article

Diet-induced weight loss alters hepatic glucocorticoid metabolism in type 2 diabetes mellitus.

Published in:

European Journal of Endocrinology, 2020, v. 182, n. 4, p. 447, doi. 10.1530/EJE-19-0901

By:

Stomby, Andreas;
Otten, Julia;
Ryberg, Mats;
Andrew, Ruth;
Walker, Brian R.;
Olsson, Tommy

Publication type:

Article

Morning plasma cortisol as a cardiovascular risk factor: findings from prospective cohort and Mendelian randomization studies.

Published in:

European Journal of Endocrinology, 2019, v. 181, n. 4, p. 429, doi. 10.1530/EJE-19-0161

By:

Crawford, Andrew A.;
Soderberg, Stefan;
Kirschbaum, Clemens;
Murphy, Lee;
Eliasson, Mats;
Ebrahim, Shah;
Smith, George Davey;
Olsson, Tommy;
Sattar, Naveed;
Lawlor, Debbie A.;
Timpson, Nicolas J.;
Reynolds, Rebecca M.;
Walker, Brian R.

Publication type:

Article