Found: 25
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Preclinical to Clinical Translation of Antibody-Drug Conjugates Using PK/PD Modeling: a Retrospective Analysis of Inotuzumab Ozogamicin.
- Published in:
- AAPS Journal, 2016, v. 18, n. 5, p. 1101, doi. 10.1208/s12248-016-9929-7
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- Article
Examining the Use of a Mechanistic Model to Generate an In Vivo/ In Vitro Correlation: Journey Through a Thought Process.
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- AAPS Journal, 2016, v. 18, n. 5, p. 1144, doi. 10.1208/s12248-016-9930-1
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- Article
Improvement of Parameter Estimations in Tumor Growth Inhibition Models on Xenografted Animals: Handling Sacrifice Censoring and Error Caused by Experimental Measurement on Larger Tumor Sizes.
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- AAPS Journal, 2016, v. 18, n. 5, p. 1262, doi. 10.1208/s12248-016-9936-8
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- Article
Understanding the Different Effects of Inhaler Design on the Aerosol Performance of Drug-Only and Carrier-Based DPI Formulations. Part 1: Grid Structure.
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- AAPS Journal, 2016, v. 18, n. 5, p. 1159, doi. 10.1208/s12248-016-9922-1
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- Article
A Novel Physiology-Based Mathematical Model to Estimate Red Blood Cell Lifespan in Different Human Age Groups.
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- AAPS Journal, 2016, v. 18, n. 5, p. 1182, doi. 10.1208/s12248-016-9923-0
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- Article
Optimal Design for Informative Protocols in Xenograft Tumor Growth Inhibition Experiments in Mice.
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- AAPS Journal, 2016, v. 18, n. 5, p. 1233, doi. 10.1208/s12248-016-9924-z
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- Article
Clinical Predictors of Venetoclax Pharmacokinetics in Chronic Lymphocytic Leukemia and Non-Hodgkin's Lymphoma Patients: a Pooled Population Pharmacokinetic Analysis.
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- AAPS Journal, 2016, v. 18, n. 5, p. 1192, doi. 10.1208/s12248-016-9927-9
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- Article
Modeling the Disease Progression from Healthy to Overt Diabetes in ZDSD Rats.
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- AAPS Journal, 2016, v. 18, n. 5, p. 1203, doi. 10.1208/s12248-016-9931-0
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- Article
How Much Surface Coating of Hydrophobic Azithromycin Is Sufficient to Prevent Moisture-Induced Decrease in Aerosolisation of Hygroscopic Amorphous Colistin Powder?
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- AAPS Journal, 2016, v. 18, n. 5, p. 1213, doi. 10.1208/s12248-016-9934-x
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- Article
Influence of Miscibility of Protein-Sugar Lyophilizates on Their Storage Stability.
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- AAPS Journal, 2016, v. 18, n. 5, p. 1225, doi. 10.1208/s12248-016-9937-7
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- Article
Defining Patient Centric Pharmaceutical Drug Product Design.
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- AAPS Journal, 2016, v. 18, n. 5, p. 1047, doi. 10.1208/s12248-016-9938-6
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- Article
Investigation of Polymer-Surfactant and Polymer-Drug-Surfactant Miscibility for Solid Dispersion.
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- AAPS Journal, 2016, v. 18, n. 5, p. 1131, doi. 10.1208/s12248-016-9939-5
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- Article
Multiscale Modeling of Antibody-Drug Conjugates: Connecting Tissue and Cellular Distribution to Whole Animal Pharmacokinetics and Potential Implications for Efficacy.
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- AAPS Journal, 2016, v. 18, n. 5, p. 1117, doi. 10.1208/s12248-016-9940-z
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- Article
Urinary 6β-Hydroxycortisol/Cortisol Ratio Most Highly Correlates With Midazolam Clearance Under Hepatic CYP3A Inhibition and Induction in Females: A Pharmacometabolomics Approach.
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- AAPS Journal, 2016, v. 18, n. 5, p. 1254, doi. 10.1208/s12248-016-9941-y
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- Article
Key to Opening Kidney for In Vitro-In Vivo Extrapolation Entrance in Health and Disease: Part I: In Vitro Systems and Physiological Data.
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- AAPS Journal, 2016, v. 18, n. 5, p. 1067, doi. 10.1208/s12248-016-9942-x
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- Article
The Impact of Model-Misspecification on Model Based Personalised Dosing.
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- AAPS Journal, 2016, v. 18, n. 5, p. 1244, doi. 10.1208/s12248-016-9943-9
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- Article
Feasibility of Singlet Analysis for Ligand Binding Assays: a Retrospective Examination of Data Generated Using the Gyrolab Platform.
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- AAPS Journal, 2016, v. 18, n. 5, p. 1300, doi. 10.1208/s12248-016-9944-8
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- Article
Metabolic Profile of 3-Acetyl-11-Keto-β-Boswellic Acid and 11-Keto-β-Boswellic Acid in Human Preparations In Vitro, Species Differences, and Bioactivity Variation.
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- AAPS Journal, 2016, v. 18, n. 5, p. 1273, doi. 10.1208/s12248-016-9945-7
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- Article
Lipophilicity in Drug Development: Too Much or Not Enough?
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- 2016
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- Publication type:
- Report
Recommendations on the Development of a Bioanalytical Assay for 4β-Hydroxycholesterol, an Emerging Endogenous Biomarker of CYP3A Activity.
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- AAPS Journal, 2016, v. 18, n. 5, p. 1056, doi. 10.1208/s12248-016-9949-3
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- Article
In Vivo Exposure of Kaempferol Is Driven by Phase II Metabolic Enzymes and Efflux Transporters.
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- AAPS Journal, 2016, v. 18, n. 5, p. 1289, doi. 10.1208/s12248-016-9951-9
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- Article
A Quantitative Review and Meta-Models of the Variability and Factors Affecting Oral Drug Absorption-Part I: Gastrointestinal pH.
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- AAPS Journal, 2016, v. 18, n. 5, p. 1309, doi. 10.1208/s12248-016-9952-8
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- Article
A Quantitative Review and Meta-models of the Variability and Factors Affecting Oral Drug Absorption-Part II: Gastrointestinal Transit Time.
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- AAPS Journal, 2016, v. 18, n. 5, p. 1322, doi. 10.1208/s12248-016-9953-7
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- Publication type:
- Article
Key to Opening Kidney for In Vitro-In Vivo Extrapolation Entrance in Health and Disease: Part II: Mechanistic Models and In Vitro-In Vivo Extrapolation.
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- AAPS Journal, 2016, v. 18, n. 5, p. 1082, doi. 10.1208/s12248-016-9959-1
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- Article
Di-Peptide-Modified Gemini Surfactants as Gene Delivery Vectors: Exploring the Role of the Alkyl Tail in Their Physicochemical Behavior and Biological Activity.
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- AAPS Journal, 2016, v. 18, n. 5, p. 1168, doi. 10.1208/s12248-016-9906-1
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- Article