Works matching IS 15507416 AND DT 2014 AND VI 16 AND IP 1

Results: 20

Large Molecule Specific Assay Operation: Recommendation for Best Practices and Harmonization from the Global Bioanalysis Consortium Harmonization Team.

Published in:

AAPS Journal, 2014, v. 16, n. 1, p. 83, doi. 10.1208/s12248-013-9542-y

By:

Stevenson, Lauren;
Kelley, Marian;
Gorovits, Boris;
Kingsley, Clare;
Myler, Heather;
Österlund, Karolina;
Muruganandam, Arumugam;
Minamide, Yoshiyuki;
Dominguez, Mario

Publication type:

Article

Estimation of Biliary Excretion of Foreign Compounds Using Properties of Molecular Structure.

Published in:

AAPS Journal, 2014, v. 16, n. 1, p. 65, doi. 10.1208/s12248-013-9541-z

By:

Sharifi, Mohsen;
Ghafourian, Taravat

Publication type:

Article

Use of Different Parameters and Equations for Calculation of IC<sub>50</sub> Values in Efflux Assays: Potential Sources of Variability in IC<sub>50</sub> Determination.

Published in:

AAPS Journal, 2014, v. 16, n. 1, p. 172, doi. 10.1208/s12248-013-9554-7

By:

Volpe, Donna A.;
Hamed, Salaheldin S.;
Zhang, Lei K.

Publication type:

Article

Mechanistic Pharmacokinetic/Target Engagement/Pharmacodynamic (PK/TE/PD) Modeling in Deciphering Interplay Between a Monoclonal Antibody and Its Soluble Target in Cynomolgus Monkeys.

Published in:

AAPS Journal, 2014, v. 16, n. 1, p. 129, doi. 10.1208/s12248-013-9545-8

By:

Wang, Weirong;
Wang, Xiaofeng;
Doddareddy, Rajitha;
Fink, Damien;
McIntosh, Thomas;
Davis, Hugh M.;
Zhou, Honghui

Publication type:

Article

Identification of Key Licorice Constituents Which Interact with Cytochrome P450: Evaluation by LC/MS/MS Cocktail Assay and Metabolic Profiling.

Published in:

AAPS Journal, 2014, v. 16, n. 1, p. 101, doi. 10.1208/s12248-013-9544-9

By:

Qiao, Xue;
Ji, Shuai;
Yu, Si-wang;
Lin, Xiong-hao;
Jin, Hong-wei;
Duan, Yao-kai;
Zhang, Liang-ren;
Guo, De-an;
Ye, Min

Publication type:

Article

Performance Properties of the Population Bioequivalence Approach for In Vitro Delivered Dose for Orally Inhaled Respiratory Products.

Published in:

AAPS Journal, 2014, v. 16, n. 1, p. 89, doi. 10.1208/s12248-013-9543-x

By:

Morgan, Beth;
Strickland, Helen

Publication type:

Article

Automation Practices in Large Molecule Bioanalysis: Recommendations from Group L5 of the Global Bioanalytical Consortium.

Published in:

AAPS Journal, 2014, v. 16, n. 1, p. 164, doi. 10.1208/s12248-013-9551-x

By:

Ahene, Ago;
Calonder, Claudio;
Davis, Scott;
Kowalchick, Joseph;
Nakamura, Takahiro;
Nouri, Parya;
Vostiar, Igor;
Wang, Yang;
Wang, Jin

Publication type:

Article

A Novel Approach to Evaluate the Pharmacokinetic Biocomparability of a Monoclonal Antibody Derived from Two Different Cell Lines Using Simultaneous Crossover Design.

Published in:

AAPS Journal, 2014, v. 16, n. 1, p. 125, doi. 10.1208/s12248-013-9547-6

By:

Han, Chao;
McIntosh, Thomas S.;
Geist, Brian J.;
Jiao, Trina;
Puchalski, Thomas A.;
Goldberg, Kenneth M.;
Yang, Tong-Yuan;
Pendley, Charles E.;
Zhou, Honghui;
Davis, Hugh M.

Publication type:

Article

Futility Rules in Bioequivalence Trials with Sequential Designs.

Published in:

AAPS Journal, 2014, v. 16, n. 1, p. 79, doi. 10.1208/s12248-013-9540-0

By:

Fuglsang, Anders

Publication type:

Article

High-Throughput Biophysical Analysis of Protein Therapeutics to Examine Interrelationships Between Aggregate Formation and Conformational Stability.

Published in:

AAPS Journal, 2014, v. 16, n. 1, p. 48, doi. 10.1208/s12248-013-9539-6

By:

Chaudhuri, Rajoshi;
Cheng, Yuan;
Middaugh, C. Russell;
Volkin, David B.

Publication type:

Article

Impact of Epigenetic Dietary Compounds on Transgenerational Prevention of Human Diseases.

Published in:

AAPS Journal, 2014, v. 16, n. 1, p. 27, doi. 10.1208/s12248-013-9538-7

By:

Yuanyuan Li;
Saldanha, Sabita N.;
Tollefsbol, Trygve O.

Publication type:

Article

Synergistic Antibiotic Combination Powders of Colistin and Rifampicin Provide High Aerosolization Efficiency and Moisture Protection.

Published in:

AAPS Journal, 2014, v. 16, n. 1, p. 37, doi. 10.1208/s12248-013-9537-8

By:

Zhou, Qi (Tony);
Gengenbach, Thomas;
Denman, John A.;
Yu, Heidi H.;
Li, Jian;
Chan, Hak Kim

Publication type:

Article

Molecular Targets and Mechanisms of Cancer Prevention and Treatment by Withaferin A, A Naturally Occurring Steroidal Lactone.

Published in:

AAPS Journal, 2014, v. 16, n. 1, p. 1, doi. 10.1208/s12248-013-9531-1

By:

Vyas, Avani R.;
Singh, Shivendra V.

Publication type:

Article

Plant Phytochemicals as Epigenetic Modulators: Role in Cancer Chemoprevention.

Published in:

AAPS Journal, 2014, v. 16, n. 1, p. 151, doi. 10.1208/s12248-013-9548-5

By:

Thakur, Vijay S.;
Deb, Gauri;
Babcook, Melissa A.;
Gupta, Sanjay

Publication type:

Article

Is Extrapolation of the Safety and Efficacy Data in One Indication to Another Appropriate for Biosimilars?

Published in:

AAPS Journal, 2014, v. 16, n. 1, p. 22, doi. 10.1208/s12248-013-9534-y

By:

Lee, Howard

Publication type:

Article

How to Regulate Nonbiological Complex Drugs (NBCD) and Their Follow-on Versions: Points to Consider.

Published in:

AAPS Journal, 2014, v. 16, n. 1, p. 15, doi. 10.1208/s12248-013-9533-z

By:

Schellekens, Huub;
Stegemann, Sven;
Weinstein, Vera;
de Vlieger, Jon S. B.;
Flühmann, Beat;
Mühlebach, Stefan;
Gaspar, Rogério;
Shah, Vinod P.;
Crommelin, Daan J. A.

Publication type:

Article

Different Pharmaceutical Products Need Similar Terminology.

Published in:

AAPS Journal, 2014, v. 16, n. 1, p. 11, doi. 10.1208/s12248-013-9532-0

By:

Crommelin, Daan J. A.;
de Vlieger, Jon S. B.;
Weinstein, Vera;
Mühlebach, Stefan;
Shah, Vinod P.;
Schellekens, Huub

Publication type:

Article

Squarticles as a Lipid Nanocarrier for Delivering Diphencyprone and Minoxidil to Hair Follicles and Human Dermal Papilla Cells.

Published in:

AAPS Journal, 2014, v. 16, n. 1, p. 140, doi. 10.1208/s12248-013-9550-y

By:

Aljuffali, Ibrahim;
Sung, Calvin;
Shen, Feng-Ming;
Huang, Chi-Ting;
Fang, Jia-You

Publication type:

Article

Design and Evaluation of a PEGylated Lipopeptide Equipped with Drug-Interactive Motifs as an Improved Drug Carrier.

Published in:

AAPS Journal, 2014, v. 16, n. 1, p. 114, doi. 10.1208/s12248-013-9536-9

By:

Peng Zhang;
Jianqin Lu;
Yixian Huang;
Wenchen Zhao;
Yifei Zhang;
Xiaolan Zhang;
Jiang Li;
Venkataramanan, Raman;
Xiang Gao;
Song Li

Publication type:

Article

Physiologically Based Pharmacokinetic Models in the Prediction of Oral Drug Exposure Over the Entire Pediatric Age Range--Sotalol as a Model Drug.

Published in:

AAPS Journal, 2014, v. 16, n. 1, p. 226, doi. 10.1208/s12248-013-9555-6

By:

Khalil, Feras;
Läer, Stephanie

Publication type:

Article