Works matching DE "SMALL molecules"

Results: 5000

The importance of co-receptors in antiretroviral therapy and novel studies on non-peptide, small molecule chemokine receptor type 5 (CCR5) antagonists.

Published in:

Istanbul Journal of Pharmacy, 2025, v. 55, n. 1, p. 200, doi. 10.26650/IstanbulJPharm.2025.1445928

By:

Aksoy, Dilek;
Ur, Füsun Göktaş

Publication type:

Article

Development and validation of an ARID1A-related immune genes risk model in evaluating prognosis and immune therapeutic efficacy for gastric cancer patients: a translational study.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1541491

By:

Zhang, Jiangtao;
Li, Jingting;
Yang, Shangfeng;
Tang, Xiaoyan;
Wang, Chunze;
Lin, Jiaxing;
Chen, Qiancheng;
Xu, Hui;
Ma, Yuanyuan;
Gao, Xiaoling

Publication type:

Article

A General Cyanine‐Based Platform for Designing Robust Dual‐Channel Near‐Infrared Fluorescent and Photoacoustic Probes.

Published in:

Advanced Functional Materials, 2025, v. 35, n. 21, p. 1, doi. 10.1002/adfm.202400597

By:

Wu, Pingzhou;
Qu, Zheng;
Zhang, Jie;
Ren, Xiaojie;
Wang, Dongqing;
Huang, Chen;
Cheng, Ke;
Qi, Junyang;
Shi, Heng;
Gan, Shenglong;
Wei, Wenyu;
Zhang, Yachao;
Lee, Chun‐Sing;
Wang, Lidai;
Sun, Hongyan

Publication type:

Article

The more we learn, the more diverse it gets: structures, functions and evolution in the Phosphofructokinase Superfamily.

Published in:

Biochemical Journal, 2025, v. 482, n. 9, p. 467, doi. 10.1042/BCJ20253024

By:

Compton, Jordan A.;
Patrick, Wayne M.

Publication type:

Article

Enzymatic Treatment of Lignin in Alkaline Homogeneous Systems: A Review on Alkaliphilic Laccases.

Published in:

ChemSusChem, 2025, v. 18, n. 10, p. 1, doi. 10.1002/cssc.202402377

By:

Delugeau, Lou;
Grelier, Stéphane;
Peruch, Frédéric

Publication type:

Article

Structure‐Binding Relationship of 2‐Amino‐1,8‐Naphthyridine Dimers: Role of Linkage Positions on DNA and RNA Recognition.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 28, p. 1, doi. 10.1002/chem.202500425

By:

Das, Bimolendu;
Kuwahara, Satoki;
Ishimaru, Ryosuke;
Murakami, Eitaro;
Harada, Yasue;
Nakatani, Kazuhiko

Publication type:

Article

Targeting mitochondrial ClpP: structural insights and therapeutic potential of ClpP agonists in cancer therapy.

Published in:

Oncology Reviews, 2025, p. 1, doi. 10.3389/or.2025.1567860

By:

Kong, Mowei;
Yu, Yang;
Shao, Shuai;
Zhang, Chunxiang

Publication type:

Article

Unveiling the role of tyrosine kinases in doxorubicin-induced cardiotoxicity and beyond Free.

Published in:

Cardiovascular Research, 2025, v. 121, n. 4, p. 530, doi. 10.1093/cvr/cvaf035

By:

Lazzarini, Edoardo;
Altomare, Claudia;
Barile, Lucio

Publication type:

Article

Redirecting glucose into anabolic pathways participates in the protective effects of NRF2 activation in the heart under stress Free.

Published in:

Cardiovascular Research, 2025, v. 121, n. 2, p. 224, doi. 10.1093/cvr/cvaf003

By:

Eschenhagen, Thomas

Publication type:

Article

罗布麻多糖特性与功能活性研究进展.

Published in:

Food Research & Development, 2025, v. 46, n. 9, p. 219, doi. 10.12161/j.issn.1005‐6521.2025.09.028

By:

韦彦安;
韦佳汝;
苑瑶;
应苗苗;
黄佳蕾;
陈小强

Publication type:

Article

Development and Optimization of a tet-on Inducible System in Komagataella phaffii.

Published in:

Modern Food Science & Technology, 2025, v. 41, n. 4, p. 163, doi. 10.13982/j.mfst.1673-9078.2025.4.0389

By:

ZOU Hongyi;
LIANG Shuli

Publication type:

Article

Constructing Stable Perovskite with Small Molecule Bridge Interface Passivation.

Published in:

Advanced Energy Materials, 2025, v. 15, n. 19, p. 1, doi. 10.1002/aenm.202405571

By:

Wang, Kai;
Yu, Bo;
Lin, Changqing;
Yao, Ruohe;
Yu, Huangzhong;
Wang, Hong

Publication type:

Article

Automated patch-clamp recordings for detecting activators and inhibitors of the epithelial sodium channel (ENaC).

Published in:

Pflügers Archiv: European Journal of Physiology, 2025, v. 477, n. 6, p. 857, doi. 10.1007/s00424-025-03087-3

By:

Sure, Florian;
Rapedius, Markus;
Diakov, Alexei;
Bertog, Marko;
Obergrussberger, Alison;
Fertig, Niels;
Korbmacher, Christoph;
Ilyaskin, Alexandr V.

Publication type:

Article

All Organic Bulk Heterojunction Antibacterial Nanoparticles Prepared by Conjugated Donor Polymer and ITIC Acceptor.

Published in:

Macromolecular Chemistry & Physics, 2025, v. 226, n. 10, p. 1, doi. 10.1002/macp.202400504

By:

Wang, Jiaxuan;
Wang, Danni;
Lv, Jing;
Li, Feng;
Zhuang, Tao;
Saparbaev, Aziz;
Makhmanov, Urol Kudratovich;
Sun, Mingliang

Publication type:

Article

Targeting the ubiquitin-proteasome pathway in systemic lupus erythematosus.

Published in:

Expert Review of Clinical Immunology, 2025, v. 21, n. 5, p. 531, doi. 10.1080/1744666X.2025.2497845

By:

Mok, Chi Chiu

Publication type:

Article

Classification and Prognostication of B‐Cell and T‐Cell Multicentric Lymphoma in Dogs Using Serum MicroRNAs.

Published in:

Veterinary & Comparative Oncology, 2025, v. 23, n. 2, p. 310, doi. 10.1111/vco.13057

By:

Ludwig, Latasha;
Treleaven, Heather;
Moorehead, Roger;
Foster, Robert A.;
Wood, R. Darren;
Ali, R. Ayesha;
Wood, Geoffrey A.

Publication type:

Article

Chaperone overexpression boosts heterologous small molecule production in Saccharomyces cerevisiae.

Published in:

Microbial Cell Factories, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12934-025-02728-7

By:

Vestergaard, Andreas M;
Nurani, Wasti;
Cachera, Paul;
Mortensen, Uffe H

Publication type:

Article

Star‐Shaped Beta‐Substituted Porphyrins with Four DPP Arms for Organic Solar Cells.

Published in:

Asian Journal of Organic Chemistry, 2025, v. 14, n. 5, p. 1, doi. 10.1002/ajoc.202400789

By:

Yuan, Lin;
Wu, Jifa;
Wu, Hanping;
Li, Yumeng;
Guo, Yinchun;
Peng, Xiaobin

Publication type:

Article

Recent Progress of Solution‐Processed Thickness‐Insensitive Cathode Interlayers for High‐Performance Organic Solar Cells.

Published in:

Advanced Functional Materials, 2025, v. 35, n. 20, p. 1, doi. 10.1002/adfm.202422023

By:

Cai, Ping;
Song, Can;
Du, Yating;
Wang, Jianbin;
Wang, Jing;
Sun, Lixian;
Gao, Feng;
Xue, Qifan

Publication type:

Article

Epstein-Barr virus latent membrane protein 1 subverts IMPDH pathways to drive B-cell oncometabolism.

Published in:

PLoS Pathogens, 2025, v. 21, n. 5, p. 1, doi. 10.1371/journal.ppat.1013092

By:

Burton, Eric M.;
Maestri, Davide;
White, Shaowen;
Liang, Jin-Hua;
Mitra, Bidisha;
Asara, John M.;
Gewurz, Benjamin E.

Publication type:

Article

A Facile Synthesis of 3‐Substituted Coumarins and Investigation of Their 3CLpro Inhibition Activity Against SARS‐CoV‐2.

Published in:

ChemistryOpen, 2025, v. 14, n. 5, p. 1, doi. 10.1002/open.202400319

By:

Choudhary, Manoj K.;
Ansari, Khalid;
Junghare, Vivek;
Nayak, Sandip K.;
Hazra, Saugata;
Mula, Soumyaditya

Publication type:

Article

SCREENING AND IN SILICO VALIDATION OF ANTIMICROBIAL PEPTIDES DERIVED FROM DNASE1 AND DNASE 1-LIKE 3.

Published in:

Obstetrics & Gynaecology Forum, 2024, v. 34, n. 3, p. 1438

By:

Priya, S. Kesava;
Priyadharsini, J. Vijayashree;
Girija, A. S. Smiline;
Sankar, P.

Publication type:

Article

SCREENING AND IN SILICO VALIDATION OF ANTIMICROBIAL PEPTIDE DERIVED FROM ELASTASE AND MYELOPEROXIDASE.

Published in:

Obstetrics & Gynaecology Forum, 2024, v. 34, n. 3, p. 820

By:

Vabushana, V. Jaya;
Priyadharsini, J. Vijayashree;
Girija, A. S. Smiline;
Ganesh, P. Sankar

Publication type:

Article

功能性胰岛素分泌细胞化学诱导方案的研究.

Published in:

Organ Transplantation / Qi Guan Yi Zhi, 2025, v. 16, n. 3, p. 435, doi. 10.12464/j.issn.1674-7445.2024269

By:

李易文;
陈继冰;
梁维萍;
高宏君;
徐之然

Publication type:

Article

A Cost-Effective Treatment of Spin–Orbit Couplings in the State-Averaged Driven Similarity Renormalization Group Second-Order Perturbation Theory.

Published in:

Molecules, 2025, v. 30, n. 9, p. 2082, doi. 10.3390/molecules30092082

By:

Wang, Meng;
Li, Chenyang

Publication type:

Article

Capillary Electrophoresis Electrospray Ionization Mass Spectrometry Reveals Metabolic Perturbations During Nematode Infection in Drosophila melanogaster.

Published in:

Molecules, 2025, v. 30, n. 9, p. 2023, doi. 10.3390/molecules30092023

By:

Tuani, Yayra T.;
Ayon, Navid J.;
Onjiko, Rosemary M.;
Choi, Sam B.;
Yadav, Shruti;
Eleftherianos, Ioannis;
Nemes, Peter

Publication type:

Article

A Selective MAP3K1 Inhibitor Facilitates Discovery of NPM1 as a Member of the Network.

Published in:

Molecules, 2025, v. 30, n. 9, p. 2001, doi. 10.3390/molecules30092001

By:

Boghean, Lidia;
Singh, Sarbjit;
Mangalaparthi, Kiran K.;
Kizhake, Smitha;
Umeta, Lelisse;
Wishka, Donn;
Grothaus, Paul;
Pandey, Akhilesh;
Natarajan, Amarnath

Publication type:

Article

Screening and transcriptomic analysis of anti- Sporothrix globosa targeting AbaA.

Published in:

Frontiers in Microbiology, 2025, p. 1, doi. 10.3389/fmicb.2025.1546020

By:

Wang, Ying;
Wu, Xiaoyan;
Fan, Xiyuan;
Han, Chanxu;
Zheng, Fangliang;
Zhang, Zhenying

Publication type:

Article

Collapsin Response Mediator Protein 2 (CRMP2) Modulates Mitochondrial Oxidative Metabolism in Knock-In AD Mouse Model.

Published in:

Cells (2073-4409), 2025, v. 14, n. 9, p. 647, doi. 10.3390/cells14090647

By:

Brustovetsky, Tatiana;
Khanna, Rajesh;
Brustovetsky, Nickolay

Publication type:

Article

Exploring gene biomarkers and targeted drugs for ferroptosis and cuproptosis in osteosarcoma: A bioinformatic approach.

Published in:

Environmental Toxicology, 2025, v. 40, n. 6, p. 891, doi. 10.1002/tox.24250

By:

Ji, Yingnan;
Liu, Lv;
Liu, Yu;
Ma, Yudong;
Ji, Zhenhua;
Wu, Xiaodan;
Zhu, Qi

Publication type:

Article

miR-369-3p Ameliorates Inflammation and Apoptosis in Intestinal Epithelial Cells via the MEK/ERK Signaling Pathway.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 9, p. 4288, doi. 10.3390/ijms26094288

By:

Scalavino, Viviana;
Piccinno, Emanuele;
Giannelli, Gianluigi;
Serino, Grazia

Publication type:

Article

A Novel Small Molecule Enhances Stable Dopamine Delivery to the Brain in Models of Parkinson's Disease.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 9, p. 4251, doi. 10.3390/ijms26094251

By:

Liu, Xiaoguang;
Hebron, Michaeline L.;
Stevenson, Max;
Moussa, Charbel

Publication type:

Article

GPR75: Advances, Challenges in Deorphanization, and Potential as a Novel Drug Target for Disease Treatment.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 9, p. 4084, doi. 10.3390/ijms26094084

By:

Han, Jingyi;
Li, Jiaojiao;
Yao, Sirui;
Wei, Zao;
Jiang, Hui;
Xu, Tao;
Zeng, Junwei;
Xu, Lin;
Han, Yong

Publication type:

Article

Isothermal Dehydrogenation of Ammonia Borane: Insights into BNH Polymers and Challenges in Regeneration.

Published in:

Chemistry - An Asian Journal, 2025, v. 20, n. 9, p. 1, doi. 10.1002/asia.202500140

By:

Castilla‐Martinez, Carlos A.;
Gaveau, Philippe;
Semsarilar, Mona;
Alonso, Bruno;
Demirci, Umit B.

Publication type:

Article

Role of SMYD2 in gastrointestinal cancer progression (Review).

Published in:

Oncology Letters, 2025, v. 29, n. 6, p. N.PAG, doi. 10.3892/ol.2025.15028

By:

Xia, Kun;
Zhou, Yaoxiang;
Xie, Youping;
Cai, Yinzhong

Publication type:

Article

Ferroptosis as a therapeutic vulnerability in MDM2 inhibition in dedifferentiated liposarcoma.

Published in:

Oncology Letters, 2025, v. 29, n. 6, p. N.PAG, doi. 10.3892/ol.2025.15015

By:

Yen, Chueh-Chuan;
Chen, Paul Chih-Hsueh;
Chen, San-Chi;
Wu, Wen-Chi;
Yen, Chiao-Han;
Lin, Yung-Chan;
Wu, Po-Kuei;
Chen, Chao-Ming;
Wang, Jir-You;
Chao, Ta-Chung;
Yang, Muh-Hwa;
Fletcher, Jonathan A.

Publication type:

Article

ANO1: central role and clinical significance in non-neoplastic and neoplastic diseases.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1570333

By:

Hu, Yanghao;
Zhang, Yifei;
He, Jiali;
Rao, Huihuang;
Zhang, Duomi;
Shen, Zhisen;
Zhou, Chongchang

Publication type:

Article

ISOLATION OF PHOSPHORYLATED CHITOSAN FROM MARINE MOLLUSES SQUID PEN AND THEIR GROWTH OF INHIBITION IN DENTAL MICROBIAL PATHOGENS.

Published in:

Obstetrics & Gynaecology Forum, 2024, v. 34, n. 2, p. 520

By:

A., Sujitha;
Arthanari, Abirami;
Ramasamy, Pasiyappazham

Publication type:

Article

Unraveling potential EGFR kinase inhibitors: Computational screening, molecular dynamics insights, and MMPBSA analysis for targeted cancer therapy development.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0321500

By:

Khan, Muhammad Naseem;
Farooq, Umar;
Khushal, Aneela;
Wani, Tanveer A.;
Zargar, Seema;
Khan, Sara

Publication type:

Article

Blocking Plasmodium Merozoite Invasion of Red Blood Cells: Molecular Docking Analysis of Small Molecule Inhibitors of the RH5-CyRPA-RIPR Complex.

Published in:

Journal of Computational Biophysics & Chemistry, 2025, v. 24, n. 8, p. 1039, doi. 10.1142/S2737416525500097

By:

Lamptey, Eugene;
Ofosu, Belinda;
Hanson, George;
Sakyi, Patrick O.;
Partey, Frederica;
Miller III, Whelton A.;
Kwofie, Samuel K.;
Mensah-Brown, Henrietta E.

Publication type:

Article

Robust Supramolecular Adhesives Based on Natural Small Molecules Through Hydrogen Bonding.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 26, p. 1, doi. 10.1002/chem.202500900

By:

Lin, Hui‐Yao;
Li, Le;
Zhang, Qi;
Qu, Da‐Hui;
Tong, Fei

Publication type:

Article

The Dinuclear Zirconocene Complex [(Cp2Zr)2(μ‐Me)(μ‐C2Ph)] as a Platform for Small Molecule Activation.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 26, p. 1, doi. 10.1002/chem.202500857

By:

Hamwi, Hanan Al;
Rippke, Mirko;
Lindenau, Kevin;
Spannenberg, Anke;
Lamac, Martin;
Reiß, Fabian;
Beweries, Torsten

Publication type:

Article

Organic Electrode Material Based on Tris‐Imidazole Ring Containing Triphenylamine (Donor)‐Anthraquinone (Acceptor) for High Performance Pseudocapacitors.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 24, p. 1, doi. 10.1002/chem.202500723

By:

Jagadale, Sudhir D.;
Bhosale, Sidhanath V.

Publication type:

Article

The Role of ER Stress and the Unfolded Protein Response in Cancer.

Published in:

Cancer Genomics & Proteomics (1109-6535), 2025, v. 22, n. 3, p. 363, doi. 10.21873/cgp.20507

By:

GHEMRAWI, ROSE;
KREMESH, SEDRA;
MOUSA, WALAA K.;
KHAIR, MOSTAFA

Publication type:

Article

Disease Modification: Comparing Diverse Approaches to Alpha-Synuclein Targeting Therapies in Parkinson's Disease.

Published in:

International Journal of High School Research, 2025, v. 7, n. 4, p. 74, doi. 10.36838/v7i4.11

By:

Kim, John

Publication type:

Article

A functionalized zwitterionic PAN fiber membrane with enhanced antifouling for stable emulsion separation.

Published in:

AIChE Journal, 2025, v. 71, n. 6, p. 1, doi. 10.1002/aic.18791

By:

Chen, Hao;
Wu, Haonan;
Dai, Yuting;
Liu, Dongfan;
Yang, Dongya;
Qiu, Fengxian;
Zhang, Tao

Publication type:

Article

Targeting the HER2-ELF3-KRAS axis: a novel therapeutic strategy for KRASG13D colorectal cancer.

Published in:

Molecular Cancer, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12943-025-02343-5

By:

Hwang, Soo-Yeon;
Seo, Yoojeong;
Park, Seojeong;
Kim, Seul-Ah;
Moon, Inhye;
Liu, Yi;
Kim, Seojeong;
Pak, Eun Seon;
Jung, Sehyun;
Kim, Hyeyoon;
Jeon, Kyung-Hwa;
Seo, Seung Hee;
Sung, Inyoung;
Lee, Heetak;
Park, So-Yeon;
Na, Younghwa;
Kim, Tae Il;
Kwon, Youngjoo

Publication type:

Article

Review of emergent polar liquid crystals from material aspects.

Published in:

Liquid Crystals Reviews, 2024, v. 12, n. 2, p. 149, doi. 10.1080/21680396.2025.2478561

By:

Liao, Qian;
Aya, Satoshi;
Huang, Mingjun

Publication type:

Article

The legacy of William M. Pardridge (1947–2024) on the science and fields concerned with the physiology of the blood-brain barrier and the transport of drugs to the brain.

Published in:

Fluids & Barriers of the CNS, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12987-025-00659-4

By:

Boado, Ruben J.;
Bickel, Ulrich;
Sumbria, Rachita K.

Publication type:

Article

Effect of CYP3A4 inhibitor and induction on the pharmacokinetics and safety of FHND9041, a novel EGFR T790M inhibitor, in healthy Chinese.

Published in:

BMC Pharmacology & Toxicology, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s40360-025-00930-2

By:

Lu, Chang;
Cheng, Dongmei;
Xie, Yunqiu;
Shang, Minghong;
Chen, Rongzhen;
Zhu, Yongqiang;
Gong, Jian;
Zhou, Huan

Publication type:

Article