Works matching DE "CELLULAR signal transduction"

Results: 5000

PI3K Inhibitors as Potential Therapeutic Agents for the Treatment of COPD with Associated Atherosclerosis.

Published in:

Drugs, 2025, v. 85, n. 6, p. 741, doi. 10.1007/s40265-025-02179-9

By:

Cazzola, Mario;
Page, Clive;
Rogliani, Paola;
Calzetta, Luigino;
Matera, Maria Gabriella

Publication type:

Article

Therapeutic Potential of Centhaquine Citrate, a Selective Alpha-2B Adrenoceptor Agonist, in the Management of Circulatory Shock.

Published in:

Drugs, 2025, v. 85, n. 6, p. 777, doi. 10.1007/s40265-025-02176-y

By:

Legrand, Matthieu;
Ranjan, Amaresh;
Rammohan, Shruthi;
De Backer, Daniel;
Ostermann, Marlies;
Gulati, Anil;
Vincent, Jean-Louis;
Khanna, Ashish K.

Publication type:

Article

Multi-omics analysis reveals Lactobacillus and Indolelactic acid involved in small intestinal adaptation of piglet with short bowel syndrome.

Published in:

Nutrition & Metabolism, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12986-025-00938-9

By:

Wang, Weipeng;
Lu, Ying;
Wu, Bo;
Peng, Shicheng;
Cai, Wei;
Xiao, Yongtao

Publication type:

Article

The weight of multiple hits: how TBI and infectious encephalitis co-modulate adverse outcomes.

Published in:

Brain Injury, 2025, v. 39, n. 7, p. 588, doi. 10.1080/02699052.2025.2450600

By:

Ladner, Liliana R.;
Tanchanco Ocampo, Collin;
Kelly, Colin;
Woodson, Caitlin M.;
Marvin, Eric;
Pickrell, Alicia M.;
Kehn-Hall, Kylene;
Theus, Michelle H.

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Article

TXNIP/NLRP3 Inflammasome Pathway in the Organismal Inflammatory Response of Elderly Patients with Severe Pneumonia Combined with Sepsis.

Published in:

International Journal of Gerontology, 2025, v. 19, n. 2, p. 103, doi. 10.6890/IJGE.202504_19(2).0008

By:

Mi Huang;
Hui Yu;
Wei Li;
Shengdao Dai

Publication type:

Article

西方蜜蜂 ATG5 基因的克隆、分析及时空表达谱测定.

Published in:

Chinese Journal of Applied Entomology, 2025, v. 62, n. 2, p. 371, doi. 10.7679/j.issn.2095-1353.2025.035

By:

吴伯文;
范小雪;
刘彩珍;
冯睿蓉;
付志英;
吴杨;
郭睿

Publication type:

Article

Identification of differentially expressed genes and pathways in the post-ovulatory ampulla of cyclic pigs through a transcriptomics approach.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10605-0

By:

Bharati, Jaya;
Kumar, Satish;
Buragohain, Bijoy Mukut;
Das, Diptesh;
Devi, Salam Jayachitra;
Mohan, N. H.;
Gupta, Vivek Kumar

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Article

Current understanding of PEAK family members in regulation of cellular signaling pathways and cancer therapy.

Published in:

Molecular & Cellular Biochemistry, 2025, v. 480, n. 6, p. 3521, doi. 10.1007/s11010-025-05219-w

By:

Alavi, Mana;
Roudi, Raheleh;
D'Angelo, Alberto;
Sobhani, Navid;
Safari, Fatemeh

Publication type:

Article

Cell-free supernatant of Clostridium leptum inhibits breast cancer cell proliferation.

Published in:

Letters in Applied Microbiology, 2025, v. 78, n. 4, p. 1, doi. 10.1093/lambio/ovaf037

By:

Wang, Qingling;
Zhao, Huan;
Ding, Huizhe;
Zhang, Hao;
Zhang, Jizhou;
Li, Liqin;
Han, Bing;
Kai, Guoyin

Publication type:

Article

Deciphering signaling mechanisms and developmental dynamics in extraembryonic mesoderm specification from hESCs.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-59491-x

By:

Niu, Baohua;
Wang, Da;
Hu, Yingjie;
Wang, Yundi;
Shi, Gaohui;
Chen, Zhongying;
Xiang, Lifeng;
Zhang, Chi;
Wei, Xuesong;
Kong, Ruize;
Cai, Hongzhi;
Ji, Weizhi;
Yin, Yu;
Li, Tianqing;
Ai, Zongyong

Publication type:

Article

Targeting mitochondrial ClpP: structural insights and therapeutic potential of ClpP agonists in cancer therapy.

Published in:

Oncology Reviews, 2025, p. 1, doi. 10.3389/or.2025.1567860

By:

Kong, Mowei;
Yu, Yang;
Shao, Shuai;
Zhang, Chunxiang

Publication type:

Article

Fine Particulate Matter (PM2.5) and the Blood-Testis Barrier: An in Vivo and in Vitro Mechanistic Study.

Published in:

Environmental Health Perspectives, 2025, v. 133, n. 3, p. 047006-1, doi. 10.1289/EHP14447

By:

Shaokai Zheng;
Nannan Zhao;
Xiaojun Lin;
Lianlian Jiang;
Chong Qiu;
Jinchen Jiang;
Zhenhao Shu;
Yingyun Qian;
Bo Liang;
Lianglin Qiu

Publication type:

Article

High SRD5A3 expression is correlated with promotion of proliferation and inhibition of apoptosis in B-cell non-Hodgkin lymphoma and suggests a poor prognosis.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0323965

By:

Wei, Shanshan;
Sun, Jie;
Wen, Jiahao;
Yu, Jianing;
Xuan, Yixuan;
Huang, Jingyu;
Yang, Jie;
Zhang, Jianfeng

Publication type:

Article

Decoding the power of saponins in ferroptosis regulation and disease intervention: a review.

Published in:

Journal of Pharmacy & Pharmacology, 2025, v. 77, n. 5, p. 593, doi. 10.1093/jpp/rgae144

By:

Ouyang, Min;
Wu, Jianhua;
Hu, Xizhuo;
Liu, Changfu;
Zhou, Dan

Publication type:

Article

Noncanonical microglial IL-1β maturation in chronic kidney disease.

Published in:

Nephrology Dialysis Transplantation, 2025, v. 40, n. 5, p. 929, doi. 10.1093/ndt/gfae239

By:

Zimmermann, Silke;
Mathew, Akash;
Bondareva, Olga;
Elwakiel, Ahmed;
Jiang, Shihai;
Rana, Rajiv;
Bechmann, Ingo;
Goldschmidt, Jürgen;
Klöting, Nora;
Sheikh, Bilal N;
Isermann, Berend

Publication type:

Article

p-Cresyl Sulfate Promotes Inflammatory Cytokine Expression in Foetal Human Osteoblasts: Implications for Pathological Bone Fragility.

Published in:

Malaysian Journal of Pathology, 2025, v. 47, n. 1, p. 166

By:

Ahmad Faizal Jelani;
Mohammad Zulkarnaen Ahmad Narihan;
Gabriele Ruth Anisah Fromming;
Dayang Erna-Zulaikha

Publication type:

Article

In Vitro multinucleated giant cell--like cells formation: An observation.

Published in:

Malaysian Journal of Pathology, 2025, v. 47, n. 1, p. 113

By:

Wei Xing KOK;
Soon Keng CHEONG;
Pooi Pooi LEONG

Publication type:

Article

Progress of microneedle targeted modulation technology in the reconstruction of immune microenvironment in diabetic wounds.

Published in:

European Journal of Medical Research, 2025, v. 30, n. 1, p. 1, doi. 10.1186/s40001-025-02667-4

By:

Wang, Shunsheng;
Cheng, Wei;
Wang, Xue;
Wu, Zhuofan;
Su, Jiandong

Publication type:

Article

Combining transcriptomics and metabolomics to analyse the mechanism of allelopathy in Cyclachaena xanthiifolia.

Published in:

BMC Plant Biology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12870-025-06704-6

By:

Yang, Zelin;
Han, Xiaoling;
Xing, Zhixiang;
He, Fumeng;
Qi, Tianshuai;
Wang, Xue;
Fu, Rao;
Du, Chong;
Feng, Xu;
Wang, Yingnan;
Yuan, Qiang;
Li, Fenglan;
Lan, Wei;
Xu, Yongqing

Publication type:

Article

Rottlerin inhibits macropinocytosis of Porcine Reproductive and Respiratory Syndrome Virus through the PKCδ-Cofilin signaling pathway.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0324500

By:

Kang, Yeonglim;
Choi, Jong-Chul;
Lee, Joong-Bok;
Park, Seung-Yong;
Oh, Changin

Publication type:

Article

Among-population proteomic differences in Schistocephalus solidus based on excretory/secretory and total body protein predictions.

Published in:

Parasites & Vectors, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13071-025-06807-x

By:

Wang, Anni;
Bolnick, Daniel I.

Publication type:

Article

Overcoming multifaceted challenges in cancer treatment: Targeting signal transduction pathways and tumor microenvironment for enhanced therapeutic efficacy.

Published in:

Journal of Applied Pharmaceutical Science, 2025, v. 15, n. 5, p. 040, doi. 10.7324/JAPS.2025.204012

By:

Ansari, Abdul Majeed;
Sharma, Naresh Kumar;
Tripathi, Kashinath;
Bhardwaj, Gautam;
Chauhan, Ritu;
Tonk, Rajiv Kumar;
Shahwan, Moyad;
Tuli, Hardeep Singh;
Chauhan, Abhishek

Publication type:

Article

Exploring the mechanism by which UCHL3 alleviates diabetic foot ulcers: FOXM1/NLRP3 inflammasome-mediated angiogenesis and endothelial cell pyroptosis.

Published in:

Journal of Orthopaedic Surgery & Research, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13018-025-05914-w

By:

Liao, Xincheng;
Jiang, Zhengying;
Fu, Zhonghua;
Guo, Guanghua

Publication type:

Article

LncRNA HCG18 regulates the progression of spinal tuberculosis by modulating the hsa-miR-146a-5p/TGF-β1/SMADs pathway.

Published in:

Journal of Orthopaedic Surgery & Research, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13018-025-05810-3

By:

Li, Feng;
Tan, Hongdong;
Zhang, Xiao;
Zhao, Xiaodong;
Li, Xiaopeng;
Chen, Gaoyang

Publication type:

Article

Liquiritin mitigates lower extremity deep vein thrombosis by inhibiting inflammation and oxidative stress via the NF-κB signaling pathway.

Published in:

Thrombosis Journal, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12959-025-00739-3

By:

Zhang, Jiacheng;
Wang, Nan;
Xin, Tianyou;
Zhu, Xiaojun;
Lang, Shengkun;
Ge, Xin

Publication type:

Article

B cell dysfunction in thalamus and brainstem involvement and high lactate caused by novel mutation of EARS2 gene.

Published in:

Italian Journal of Pediatrics, 2025, v. 51, n. 1, p. 1, doi. 10.1186/s13052-025-01999-5

By:

Wen, Yu;
Huang, Yanmei;
Zhang, Wendi;
Chen, Ping;
Hu, Xiufen;
Xiong, Xin;
Luo, Li

Publication type:

Article

The antineoplastic effects of nuciferine on hepatocellular carcinoma are associated with suppression of the HER2-AKT/ERK1/2 signaling pathway.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02695-w

By:

Li, Tiantian;
Wang, Weidong;
Zhu, Mingwei;
Dong, Tianxiu;
Jiang, Jian;
Li, Zizhuo;
An, Tingting;
Chen, Xi;
Mao, Yingxuan;
Chen, Yaodong;
Yang, Xiuhua

Publication type:

Article

Single-cell transcriptomic landscape reveals complex cellular heterogeneity and dysregulated signaling pathways in nasopharyngeal carcinoma.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02506-2

By:

Zhang, Xiaoyan;
Guan, Zuojia;
Xu, Zhan

Publication type:

Article

Curcumin: a potential anti-photoaging agent.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1559032

By:

Nie, Yuhong;
Li, Yiming

Publication type:

Article

Correlation of heat shock protein 1 expression with progression and prognosis of non-small cell lung cancer.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1553248

By:

Wang, Rui;
Guo, Rongqi;
Huang, Tianyi;
Lu, Yu;
Zhang, Weisong;
Wang, Yihao;
Ni, Qinggan;
Song, Jianxiang;
Li, Xia

Publication type:

Article

Vitamin D inhibits apoptosis in THP-1 cells infected with mycobacterium tuberculosis through TNF signaling pathway.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1525922

By:

Yang, Yusheng;
Deng, Jiezhong;
Liu, Pan;
He, Jinyue;
Tan, Jiulin;
Yu, Bo;
Bai, Yun;
Luo, Fei;
Xu, Jianzhong;
Zhang, Zehua

Publication type:

Article

Loss-of-function Gαs rare disease variants exert mutation-specific effects on GPCR signaling.

Published in:

Science Signaling, 2025, v. 18, n. 887, p. 1, doi. 10.1126/scisignal.ado7543

By:

Redfern-Nichols, Theo;
O'Brien, Shannon L.;
Huang, Xianglin;
Medel-Lacruz, Brian;
Calebiro, Davide;
Selent, Jana;
Ladds, Graham;
Marti-Solano, Maria

Publication type:

Article

Total Glycosides of Paeony Activates PI3K/Akt Pathway to Alleviate Cardiomyocyte Hypertrophy Induced by AngII.

Published in:

Cell Biochemistry & Biophysics, 2025, v. 83, n. 2, p. 2059, doi. 10.1007/s12013-024-01616-y

By:

Sheng, Letian;
Shen, Mengjiao;
Shao, Danyan

Publication type:

Article

Alteration in Ca2+ signaling-related genes in schizophrenia.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10595-z

By:

Taheri, Mohammad;
Pourtavakoli, Ashkan;
Seyyedesfahani, Vidasadat;
Eslami, Solat;
Sayad, Arezou;
Ghafouri-Fard, Soudeh

Publication type:

Article

Correction: LncRNA H19 inhibited dermal papilla cell senescence process through miR-29a by targeting Wnt/β-catenin signaling pathway.

Published in:

2025

By:

Liu, Zhenyu;
Li, Shenyu;
Yang, Qilin;
Cao, Guiyuan;
Yan, Wenjie;
Jiang, Siyuan;
Qiao, Ruilong;
Cai, Bozhi;
Wu, Zhihao;
Lin, Changmin;
Zhu, Ningxia

Publication type:

Correction Notice

LncRNA H19 inhibited dermal papilla cell senescence process through miR-29a by targeting Wnt/β-catenin signaling pathway.

Published in:

Archives of Dermatological Research, 2025, v. 317, n. 1, p. 1, doi. 10.1007/s00403-025-04128-8

By:

Liu, Zhenyu;
Li, Shenyu;
Yang, Qilin;
Cao, Guiyuan;
Yan, Wenjie;
Jiang, Siyuan;
Qiao, Ruilong;
Cai, Bozhi;
Wu, Zhihao;
Lin, Changmin;
Zhu, Ningxia

Publication type:

Article

Evolution and classification of Ser/Thr phosphatase PP2C family in bacteria: Sequence conservation, structures, domain distribution.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0322880

By:

Li, Hang;
Li, Rui;
Yu, Haoyue;
Zhang, Youhuan;
Feng, Hong

Publication type:

Article

NETosis in Autoimmunity: Cell-Mediated vs. Ab-Mediated.

Published in:

Iranian Journal of Public Health, 2025, v. 54, n. 5, p. 1113, doi. 10.18502/ijph.v54i5.18648

By:

Babaei, Shabnam;
Fadaee, Manouchehr

Publication type:

Article

Increased Expression of RCN1P2, TPM3P9, and HSP90AB3P as Non-Coding RNA in Gastric Cancer Linked to Proliferative, Inflammatory and Metastatic Pathways through a Competing Endogenous RNAs Network.

Published in:

Iranian Journal of Public Health, 2025, v. 54, n. 5, p. 1074, doi. 10.18502/ijph.v54i5.18642

By:

Sadeghi, Ensieh Sagheb;
Bioky, Zahra Amrollahy;
Hokmabadi, Mahsa;
Asadollahi, Samira;
Sarhadi, Fatemeh;
Dolatabadi, Nasrin Fattahi;
Zamani, Atefeh;
Mahdevar, Mohammad;
Peymani, Maryam

Publication type:

Article

Molecular Pathways in Idiopathic Pulmonary Fibrosis: A Review of Novel Insights for Drug Design.

Published in:

Drug Development Research, 2025, v. 86, n. 3, p. 1, doi. 10.1002/ddr.70094

By:

Kahvecioglu, Dilay

Publication type:

Article

Dihydroartemisinin Attenuates Radiation‐Induced Lung Injury by Inhibiting the cGAS/STING/NF‐κB Signaling Pathway.

Published in:

Drug Development Research, 2025, v. 86, n. 3, p. 1, doi. 10.1002/ddr.70090

By:

Wang, Cailan;
Lin, Xinyi;
Guan, Shichun;
Wu, Qiaoyuan;
Liang, Shixiong

Publication type:

Article

Targeting the NCAPD3 gene activates EGFR and ASNS as two pivotal contributors to gastric cancer progression.

Published in:

Gastroenterology & Hepatology from Bed to Bench, 2024, v. 17, n. 4, p. 400, doi. 10.22037/ghfbb.v17i4.3031

By:

Bandarian, Fatemeh;
Razi, Farideh;
Jahani-Sharafat, Somayeh;
Nejad, Mohammad Rostami;
Arjmand, Babak;
Farahani, Masoumeh

Publication type:

Article

Pulmonary fibrosis through the prism of NLRP3 inflammasome: mechanistic pathways and prospective therapeutic innovations.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1593729

By:

Wang, Mengxue;
Xie, Yuanyuan;
Cao, Yuqing;
Yu, Bing;
Dai, Qingqing

Publication type:

Article

Role and Significance of MicroRNAs in the Relationship Between Obesity and Cancer.

Published in:

Balkan Medical Journal, 2025, v. 42, n. 3, p. 188, doi. 10.4274/balkanmedj.galenos.2025.2025-3-60

By:

Doghish, Ahmed S.;
Mansour, Reda M.;
Mageed, Sherif S. Abdel;
Moustafa, Hebatallah Ahmed Mohamed;
Mohammed, Osama A.;
Elesawy, Ahmed E.;
Rizk, Nehal I.

Publication type:

Article

Harnessing the Power of Vitexin as a Vitamin D Receptor Agonist in Colorectal Cancer: A New Frontier.

Published in:

Balkan Medical Journal, 2025, v. 42, n. 3, p. 276, doi. 10.4274/balkanmedj.galenos.2024.2024-10-105

By:

Mubeen, Manahil;
Ali, Hafsa;
Zehra, Syeda Sabika;
Khan, Aman

Publication type:

Article

Molecular pathways of ketamine: A systematic review of immediate and sustained effects on PTSD.

Published in:

Psychopharmacology, 2025, v. 242, n. 6, p. 1197, doi. 10.1007/s00213-025-06756-4

By:

Wellington, Nathan J.;
Boųcas, Ana P.;
Lagopoulos, Jim;
Quigley, Bonnie L.;
Kuballa, Anna V.

Publication type:

Article

Characterisation of Gene Expression in Canine Invasive Urothelial Carcinoma Using a NanoString‐Based Urine Assay.

Published in:

Veterinary & Comparative Oncology, 2025, v. 23, n. 2, p. 205, doi. 10.1111/vco.13046

By:

Kuerbitz, Ellen Marie;
Dhawan, Deepika;
Utturkar, Sagar;
Sola, Mario Francis;
Enstrom, Alexander William;
Fourez, Lindsey Marie;
Knapp, Deborah Wagner

Publication type:

Article

Electroacupuncture at ST25 mediated glial cells pruning of pancreatic TRPV1 neural synapse responds to neuropathy-associated beta cell dysfunction.

Published in:

Chinese Medicine, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13020-025-01099-w

By:

Liu, Yun;
Xie, Jiahui;
Yu, Zhi;
Gong, Meirong;
Li, Qian;
Yang, Guanhu;
Xu, Bin;
Xu, Tiancheng

Publication type:

Article

Synthesis and anti-hepatic fibrosis activity of novel matrine tricyclic derivatives.

Published in:

Australian Journal of Chemistry, 2025, v. 78, n. 5, p. 1, doi. 10.1071/CH24160

By:

Wang, Yongchuang;
Yang, Hang;
Tang, Wenming;
Zhou, Luozhu;
Wang, Chuanhao;
Huang, Anhua;
Zhang, Daozuan;
Yao, Zheng;
Li, Wei;
Zhang, Wannian;
Wu, Yuelin;
Xu, Weiheng;
Miao, Zhenyuan

Publication type:

Article

Inside Cover Picture.

Published in:: Chinese Journal of Chemistry, 2025, v. 43, n. 12, p. 1330, doi. 10.1002/cjoc.70102
Publication type:: Article