Works matching IS 23649534 AND DT 2022 AND VI 8 AND IP 1

Results: 22

Meeting report: Advancing accelerated regulatory review with Real-Time Oncology Review (RTOR), Project Orbis, and the Product Quality Assessment Aid.
Published in:
AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00066-1
By:
- Algorri, Marquerita;
- Acharya, Ajay;
- Bernstein, James;
- Cauchon, Nina S.;
- Chen, Xiao Hong;
- Huynh-Ba, Kim;
- Krantz, Carol;
- Li, Tao;
- Li, Yiwei;
- McLamore, Sherita;
- Roberts, Scott W.;
- Schwinke, David;
- Shah, Rakhi;
- Schirmer, Andrea;
- Strickland, Helen;
- Tang, Kin;
- Watson, Timothy
Publication type:
Article
Verification of nanoparticle formation, skin permeation, and apoptosis using nobiletin as a methoxyflavonoid derivative.
Published in:
AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00065-2
By:
- Inoue, Yutaka;
- Ishizawa, Moe;
- Itakura, Shoko;
- Tanikawa, Takashi;
- Todo, Hiroaki
Publication type:
Article
Glycopeptide antibiotic drug stability in aqueous solution.
Published in:
AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00067-0
By:
- Jakaria, Sardar M.;
- Budil, David E.;
- Murtagh, James
Publication type:
Article
Results from in vitro and in vivo studies evaluating the bioavailability, effects of food, and administration as crushed tablet suspension on vericiguat pharmacokinetics.
Published in:
AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00063-4
By:
- Becker, Corina;
- Boettcher, Michael;
- Muenster, Uwe;
- Loewen, Stephanie;
- Lobmeyer, Maximilian;
- Mueck, Wolfgang
Publication type:
Article
Formulation mitigations for particle formation induced by enzymatic hydrolysis of polysorbate 20 in protein-based drug products: insights from a full-factorial longitudinal study.
Published in:
AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00064-3
By:
- Yuk, Inn H.;
- Koulis, Theo;
- Doshi, Nidhi;
- Gregoritza, Kathrin;
- Hediger, Constanze;
- Lebouc-Haefliger, Vanessa;
- Giddings, Jamie;
- Khan, Tarik A.
Publication type:
Article
Heat pre-treatment can abolish anti-drug antibody interference in ligand binding pharmacokinetic assays.
Published in:
AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00056-3
By:
- Poulsen, Svend;
- Jørgensen, Louise;
- Galle, Pia Søndergaard
Publication type:
Article
Pharmacokinetic and pharmacodynamic analyses of terlipressin in patients with hepatorenal syndrome.
Published in:
AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00052-7
By:
- Wang, Xiaofeng;
- Jamil, Khurram
Publication type:
Article
Understanding the implication of Kawakita model parameters using in-die force-displacement curve analysis for compacted and non-compacted API powders.
Published in:
AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00053-6
By:
- Rashid, Iyad;
- Haddadin, Rula Raji;
- Alkafaween, Ashaar Abdulsalam;
- Alkaraki, Rawan Nayef;
- Alkasasbeh, Rehan Mohammad
Publication type:
Article
The degradation of poloxamer 188 in buffered formulation conditions.
Published in:
AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00055-4
By:
- Chen, Wei;
- Stolz, Siegfried;
- Wegbecher, Vincent;
- Parakkattel, Dixy;
- Haeuser, Christina;
- Oltra, Nuria Sancho;
- Kishore, Ravuri S. K.;
- Bond, Steven;
- Bell, Christian;
- Kopf, Robert
Publication type:
Article
Therapeutic effects of dracocephalum heterophyllum in collagen-induced arthritis.
Published in:
AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00051-8
By:
- Wang, Yalan;
- Lai, Dongming;
- Geng, Yunyun;
- Shang, Peng;
- Wang, Pu
Publication type:
Article
Stability of levothyroxine tablets in blister packaging versus bottles and vials under simulated in-use conditions.
Published in:
AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00062-5
By:
- Chun, Jonathan
Publication type:
Article
Technical transfer and commercialisation of lyophilised biopharmaceuticals — application of lyophiliser characterisation and comparability.
Published in:
AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00059-0
By:
- Cullen, Sean;
- Walsh, Emma;
- Gervasi, Valeria;
- Khamar, Dikshitkumar;
- McCoy, Timothy R.
Publication type:
Article
PLGA-based nanoparticles for the treatment of cancer: current strategies and perspectives.
Published in:
AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00060-7
By:
- Alvi, Maria;
- Yaqoob, Azka;
- Rehman, Kanwal;
- Shoaib, Syed Muhammad;
- Akash, Muhammad Sajid Hamid
Publication type:
Article
Safety and pharmacokinetics of a highly bioavailable resveratrol preparation (JOTROL TM).
Published in:
AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00058-1
By:
- Kemper, Christopher;
- Behnam, Dariush;
- Brothers, Shaun;
- Wahlestedt, Claes;
- Volmar, Claude-Henry;
- Bennett, Daniel;
- Hayward, Marshall
Publication type:
Article
Correction: Safety and pharmacokinetics of a highly bioavailable resveratrol preparation (JOTROL TM).
Published in:
2022
By:
- Kemper, Christopher;
- Behnam, Dariush;
- Brothers, Shaun;
- Wahlestedt, Claes;
- Volmar, Claude-Henry;
- Bennett, Daniel;
- Hayward, Marshall
Publication type:
Correction Notice
Safety and pharmacokinetics of a highly bioavailable resveratrol preparation (JOTROL TM).
Published in:
AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00058-1
By:
- Kemper, Christopher;
- Benham, Dariush;
- Brothers, Shaun;
- Wahlestedt, Claes;
- Volmar, Claude-Henry;
- Bennett, Daniel;
- Hayward, Marshall
Publication type:
Article
Utilizing cross-product prior knowledge to rapidly de-risk chemical liabilities in therapeutic antibody candidates.
Published in:
AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00057-2
By:
- Jacobitz, Alex W.;
- Rodezno, Wilfredo;
- Agrawal, Neeraj J.
Publication type:
Article
Molecular docking assisted exploration on solubilization of poorly soluble drug remdesivir in sulfobutyl ether-tycyclodextrin.
Published in:
AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00054-5
By:
- Zhang, Yumeng;
- Zhao, Zhouming;
- Wang, Kai;
- Lyu, Kangjie;
- Yao, Cai;
- Li, Lin;
- Shen, Xia;
- Liu, Tengfei;
- Guo, Xiaodi;
- Li, Haiyan;
- Wang, Wenshou;
- Lai, Tsai-Ta
Publication type:
Article
Molecular docking assisted exploration on solubilization of poorly soluble drug remdesivir in sulfobutyl ether-tycyclodextrin.
Published in:
AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00054-5
By:
- Zhang, Yumeng;
- Zhao, Zhouming;
- Wang, Kai;
- Lyu, Kangjie;
- Yao, Cai;
- Li, Lin;
- Shen, Xia;
- Liu, Tengfei;
- Guo, Xiaodi;
- Li, Haiyan;
- Wang, Wenshou;
- Lai, Tsai-Ta
Publication type:
Article
Impact of charge patches on tumor disposition and biodistribution of therapeutic antibodies.
Published in:
AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-021-00048-9
By:
- Stüber, Jakob C.;
- Rechberger, Karin F.;
- Miladinović, Saša M.;
- Pöschinger, Thomas;
- Zimmermann, Tamara;
- Villenave, Remi;
- Eigenmann, Miro J.;
- Kraft, Thomas E.;
- Shah, Dhaval K.;
- Kettenberger, Hubert;
- Richter, Wolfgang F.
Publication type:
Article
Best practices for the development and fit-for-purpose validation of biomarker methods: a conference report.
Published in:
AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-021-00050-1
By:
- Mathews, Joel;
- Amaravadi, Lakshmi;
- Eck, Steven;
- Stevenson, Lauren;
- Wang, Yow-Ming C.;
- Devanarayan, Viswanath;
- Allinson, John;
- Lundsten, Kelly;
- Gunsior, Michele;
- Ni, Yan G.;
- Pepin, Marc-Olivier;
- Gagnon, Audrey;
- Sheldon, Curtis;
- Trampont, Paul C.;
- Litwin, Virginia
Publication type:
Article
Development and validation of a headspace GC-MS method to evaluate the interconversion of impurities and the product quality of liquid hand sanitizers.
Published in:
AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-021-00049-8
By:
- Abrigo, Nicolas;
- Ruzicka, Connie;
- Faustino, Patrick;
- Stiber, Neil;
- NguyenPho, Agnes;
- O'Connor, Thomas;
- Shakleya, Diaa
Publication type:
Article

Works matching IS 23649534 AND DT 2022 AND VI 8 AND IP 1

Meeting report: Advancing accelerated regulatory review with Real-Time Oncology Review (RTOR), Project Orbis, and the Product Quality Assessment Aid.

Verification of nanoparticle formation, skin permeation, and apoptosis using nobiletin as a methoxyflavonoid derivative.

Glycopeptide antibiotic drug stability in aqueous solution.

Results from in vitro and in vivo studies evaluating the bioavailability, effects of food, and administration as crushed tablet suspension on vericiguat pharmacokinetics.

Formulation mitigations for particle formation induced by enzymatic hydrolysis of polysorbate 20 in protein-based drug products: insights from a full-factorial longitudinal study.

Heat pre-treatment can abolish anti-drug antibody interference in ligand binding pharmacokinetic assays.

Pharmacokinetic and pharmacodynamic analyses of terlipressin in patients with hepatorenal syndrome.

Understanding the implication of Kawakita model parameters using in-die force-displacement curve analysis for compacted and non-compacted API powders.

The degradation of poloxamer 188 in buffered formulation conditions.

Therapeutic effects of dracocephalum heterophyllum in collagen-induced arthritis.

Stability of levothyroxine tablets in blister packaging versus bottles and vials under simulated in-use conditions.

Technical transfer and commercialisation of lyophilised biopharmaceuticals — application of lyophiliser characterisation and comparability.

PLGA-based nanoparticles for the treatment of cancer: current strategies and perspectives.

Safety and pharmacokinetics of a highly bioavailable resveratrol preparation (JOTROL <sup>TM</sup>).

Correction: Safety and pharmacokinetics of a highly bioavailable resveratrol preparation (JOTROL <sup>TM</sup>).

Safety and pharmacokinetics of a highly bioavailable resveratrol preparation (JOTROL <sup>TM</sup>).

Utilizing cross-product prior knowledge to rapidly de-risk chemical liabilities in therapeutic antibody candidates.

Molecular docking assisted exploration on solubilization of poorly soluble drug remdesivir in sulfobutyl ether-tycyclodextrin.

Molecular docking assisted exploration on solubilization of poorly soluble drug remdesivir in sulfobutyl ether-tycyclodextrin.

Impact of charge patches on tumor disposition and biodistribution of therapeutic antibodies.

Best practices for the development and fit-for-purpose validation of biomarker methods: a conference report.

Development and validation of a headspace GC-MS method to evaluate the interconversion of impurities and the product quality of liquid hand sanitizers.