Genome sequences and annotation of two urinary isolates of E. coli.

Price, Travis K.; Mehrtash, Arya; Kalesinskas, Laurynas; Malk, Kema; Hilt, Evann E.; Putonti, Catherine; Wolfe, Alan J.

The genus Escherichia includes pathogens and commensals. Bladder infections (cystitis) result most often from colonization of the bladder by uropathogenic E. coli strains. In contrast, a poorly defined condition called asymptomatic bacteriuria results from colonization of the bladder with E. coli strains without symptoms. As part of an on-going attempt to identify and characterize the newly discovered female urinary microbiota, we report the genome sequences and annotation of two urinary isolates of E. coli: one (E78) was isolated from a female patient who self-reported cystitis; the other (E75) was isolated from a female patient who reported that she did not have symptoms of cystitis. Whereas strain E75 is most closely related to an avian extraintestinal pathogen, strain E78 is a member of a clade that includes extraintestinal strains often found in the human bladder. Both genomes are uncommonly rich in prophages.

ESCHERICHIA coli; NUCLEOTIDE sequencing; PROPHAETHON; PROPHAETHONTIDAE; CYSTITIS; DIAGNOSIS

Standards in Genomic Sciences, 2016, p1

1944-3277

Academic Journal

10.1186/s40793-016-0202-6