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- Title
Focal ischemic stroke modifies microglia-derived exosomal miRNAs: potential role of mir-212-5p in neuronal protection and functional recovery.
- Authors
Li, Si-Si; Wu, Jia-Jia; Xing, Xiang-Xin; Li, Yu-Lin; Ma, Jie; Duan, Yu-Jie; Zhang, Jun-Peng; Shan, Chun-Lei; Hua, Xu-Yun; Zheng, Mou-Xiong; Xu, Jian-Guang
- Abstract
Ischemic stroke is a severe type of stroke with high disability and mortality rates. In recent years, microglial exosome-derived miRNAs have been shown to be promising candidates for the treatment of ischemic brain injury and exert neuroprotective effects. Mechanisms underlying miRNA dysregulation in ischemic stroke are still being explored. Here, we aimed to verify whether miRNAs derived from exosomes exert effects on functional recovery.
- Publication
Biological research, 2023, Vol 56, Issue 1, p52
- ISSN
0717-6287
- Publication type
Journal Article
- DOI
10.1186/s40659-023-00458-x