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Results: 36

Silencing of STEAP3 suppresses cervical cancer cell proliferation and migration via JAK/STAT3 signaling pathway.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00370-2
By:
- Zhao, Zouyu;
- Yu, Panpan;
- Wang, Yan;
- Li, Hong;
- Qiao, Hui;
- Sun, Chongfeng;
- Zhu, Lina;
- Yang, Ping
Publication type:
Article
Similar deficiencies, different outcomes: succinate dehydrogenase loss in adrenal medulla vs. fibroblast cell culture models of paraganglioma.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00369-9
By:
- Al Khazal, Fatimah J.;
- Bhat, Sanjana Mahadev;
- Zhu, Yuxiang;
- de Araujo Correia, Cristina M.;
- Zhou, Sherry X.;
- Wilbanks, Brandon A.;
- Folmes, Clifford D.;
- Sieck, Gary C.;
- Favier, Judith;
- Maher III, L. James
Publication type:
Article
A whole food, plant-based diet reduces amino acid levels in patients with metastatic breast cancer.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00368-w
By:
- Scales, TashJaé Q.;
- Smith, Bradley;
- Blanchard, Lisa M.;
- Wixom, Nellie;
- Tuttle, Emily T.;
- Altman, Brian J.;
- Peppone, Luke J.;
- Munger, Joshua;
- Campbell, Thomas M.;
- Campbell, Erin K.;
- Harris, Isaac S.
Publication type:
Article
PFKFB3-dependent redox homeostasis and DNA repair support cell survival under EGFR-TKIs in non-small cell lung carcinoma.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00366-y
By:
- Lypova, Nadiia;
- Dougherty, Susan M.;
- Clem, Brian F.;
- Feng, Jing;
- Yin, Xinmin;
- Zhang, Xiang;
- Li, Xiaohong;
- Chesney, Jason A.;
- Imbert-Fernandez, Yoannis
Publication type:
Article
TDO2 inhibition counters Benzo[a]pyrene-induced immune evasion and suppresses tumorigenesis in lung adenocarcinoma.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00365-z
By:
- Taş, İsa;
- Varlı, Mücahit;
- Pulat, Sultan;
- Sim, Hyun Bo;
- Kim, Jong-Jin;
- Kim, Hangun
Publication type:
Article
Glutaminolysis is associated with mitochondrial pathway activation and can be therapeutically targeted in glioblastoma.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00364-0
By:
- Miki, Kenji;
- Yagi, Mikako;
- Hatae, Ryusuke;
- Otsuji, Ryosuke;
- Miyazaki, Takahiro;
- Goto, Katsuhiro;
- Setoyama, Daiki;
- Fujioka, Yutaka;
- Sangatsuda, Yuhei;
- Kuga, Daisuke;
- Higa, Nayuta;
- Takajo, Tomoko;
- Hajime, Yonezawa;
- Akahane, Toshiaki;
- Tanimoto, Akihide;
- Hanaya, Ryosuke;
- Kunisaki, Yuya;
- Uchiumi, Takeshi;
- Yoshimoto, Koji
Publication type:
Article
Complete inhibition of liver acetyl-CoA carboxylase activity is required to exacerbate liver tumorigenesis in mice treated with diethylnitrosamine.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00363-1
By:
- Shrestha, Riya;
- Vancuylenburg, Calum S.;
- Beretta, Martina;
- Zhou, Mingyan;
- Shah, Divya P.;
- Olzomer, Ellen M.;
- Richards, Sian L.;
- Hoehn, Kyle L.;
- Byrne, Frances L.
Publication type:
Article
CYP19A1 regulates chemoresistance in colorectal cancer through modulation of estrogen biosynthesis and mitochondrial function.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00360-4
By:
- Wang, Yang;
- Ji, Qiang;
- Cao, Ning;
- Ge, Guijie;
- Li, Xiaomin;
- Liu, Xiangdong;
- Mi, Yanqi
Publication type:
Article
RHOF promotes Snail1 lactylation by enhancing PKM2-mediated glycolysis to induce pancreatic cancer cell endothelial–mesenchymal transition.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00362-2
By:
- Zhao, Rui;
- Yi, Yanmin;
- Liu, Han;
- Xu, Jianwei;
- Chen, Shuhai;
- Wu, Dong;
- Wang, Lei;
- Li, Feng
Publication type:
Article
RNF2 promotes chondrosarcoma progression by regulating ubiquitination and degradation of CBX7.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00359-x
By:
- Wu, Yue;
- Huang, Zheng;
- Luo, Ping;
- Xiang, Zhong;
- Zhang, Meng;
- Chen, Zhiwu;
- Zhou, Yalu;
- Li, Jiameng
Publication type:
Article
Unraveling the glycosphingolipid metabolism by leveraging transcriptome-weighted network analysis on neuroblastic tumors.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00358-y
By:
- Ustjanzew, Arsenij;
- Nedwed, Annekathrin Silvia;
- Sandhoff, Roger;
- Faber, Jörg;
- Marini, Federico;
- Paret, Claudia
Publication type:
Article
Pancreatic cancer tumor organoids exhibit subtype-specific differences in metabolic profiles.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00357-z
By:
- Ali, Hassan A.;
- Karasinska, Joanna M.;
- Topham, James T.;
- Johal, Danisha;
- Kalloger, Steve;
- Metcalfe, Andrew;
- Warren, Cassia S.;
- Miyagi, Anthony;
- Tao, Lan V.;
- Kevorkova, Maya;
- Chafe, Shawn C.;
- McDonald, Paul C.;
- Dedhar, Shoukat;
- Parker, Seth J.;
- Renouf, Daniel J.;
- Schaeffer, David F.
Publication type:
Article
Metabolism of primary high-grade serous ovarian carcinoma (HGSOC) cells under limited glutamine or glucose availability.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00355-1
By:
- Šimčíková, Daniela;
- Gardáš, Dominik;
- Pelikán, Tomáš;
- Moráň, Lukáš;
- Hruda, Martin;
- Hložková, Kateřina;
- Pivetta, Tiziana;
- Hendrych, Michal;
- Starková, Júlia;
- Rob, Lukáš;
- Vaňhara, Petr;
- Heneberg, Petr
Publication type:
Article
PAF1/HIF1α axis rewires the glycolytic metabolism to fuel aggressiveness of pancreatic cancer.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00354-2
By:
- Ogunleye, Ayoola O.;
- Gayen, Neelanjana;
- Rauth, Sanchita;
- Marimuthu, Saravanakumar;
- Nimmakayala, Rama Krishna;
- Alsafwani, Zahraa W.;
- Cox, Jesse L.;
- Batra, Surinder K.;
- Ponnusamy, Moorthy P.
Publication type:
Article
Real-time assessment of relative mitochondrial ATP synthesis response against inhibiting and stimulating substrates (MitoRAISE).
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00353-3
By:
- Chang, Eun Sol;
- Song, Kyoung;
- Song, Ji-Young;
- Sung, Minjung;
- Lee, Mi-Sook;
- Oh, Jung Han;
- Kim, Ji-Yeon;
- Park, Yeon Hee;
- Jung, Kyungsoo;
- Choi, Yoon-La
Publication type:
Article
Epigenetic repression of de novo cysteine synthetases induces intra-cellular accumulation of cysteine in hepatocarcinoma by up-regulating the cystine uptake transporter xCT.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00352-4
By:
- Yamauchi, Tomoaki;
- Okano, Yumi;
- Terada, Daishu;
- Yasukochi, Sai;
- Tsuruta, Akito;
- Tsurudome, Yuya;
- Ushijima, Kentaro;
- Matsunaga, Naoya;
- Koyanagi, Satoru;
- Ohdo, Shigehiro
Publication type:
Article
METTL16 regulates the mRNA stability of FBXO5 via m6A modification to facilitate the malignant behavior of breast cancer.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00351-5
By:
- Wang, Runying;
- Gao, Xingjie;
- Xie, Luhan;
- Lin, Jiaqi;
- Ren, Yanying
Publication type:
Article
The relationship between Stroma AReactive Invasion Front Areas (SARIFA), Warburg-subtype and survival: results from a large prospective series of colorectal cancer patients.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00349-z
By:
- Offermans, Kelly;
- Reitsam, Nic G.;
- Simons, Colinda C. J. M.;
- Grosser, Bianca;
- Zimmermann, Jessica;
- Grabsch, Heike I.;
- Märkl, Bruno;
- van den Brandt, Piet A.
Publication type:
Article
Subclinical dose irradiation triggers human breast cancer migration via mitochondrial reactive oxygen species.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00347-1
By:
- Rondeau, Justin D.;
- Van de Velde, Justine A.;
- Bouidida, Yasmine;
- Sonveaux, Pierre
Publication type:
Article
Long-acting Erwinia chrysanthemi, Pegcrisantaspase, induces alternate amino acid biosynthetic pathways in a preclinical model of pancreatic ductal adenocarcinoma.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00346-2
By:
- Bollino, Dominique;
- Hameed, Kanwal;
- Bhat, Anusha;
- Zarrabi, Arveen;
- Casildo, Andrea;
- Ma, Xinrong;
- Tighe, Kayla M;
- Carter-Cooper, Brandon;
- Strovel, Erin T.;
- Lapidus, Rena G.;
- Emadi, Ashkan
Publication type:
Article
Sulfatide imaging identifies tumor cells in colorectal cancer peritoneal metastases.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00345-3
By:
- Sarcinelli, G. M.;
- Varinelli, L.;
- Ghislanzoni, S.;
- Padelli, F.;
- Lorenzini, D.;
- Vingiani, A.;
- Milione, M.;
- Guaglio, M.;
- Kusamura, S.;
- Deraco, M.;
- Pruneri, G.;
- Gariboldi, M.;
- Baratti, D.;
- Bongarzone, I.
Publication type:
Article
Glycemic status, insulin resistance, and mortality from lung cancer among individuals with and without diabetes.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00344-4
By:
- Cho, In Young;
- Chang, Yoosoo;
- Sung, Eunju;
- Park, Boyoung;
- Kang, Jae-Heon;
- Shin, Hocheol;
- Wild, Sarah H.;
- Byrne, Christopher D.;
- Ryu, Seungho
Publication type:
Article
Metabolic alterations and cellular responses to β-Hydroxybutyrate treatment in breast cancer cells.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00339-1
By:
- Fulman-Levy, Hadas;
- Cohen-Harazi, Raichel;
- Levi, Bar;
- Argaev-Frenkel, Lital;
- Abramovich, Ifat;
- Gottlieb, Eyal;
- Hofmann, Sarah;
- Koman, Igor;
- Nesher, Elimelech
Publication type:
Article
Disrupting Na+ ion homeostasis and Na+/K+ ATPase activity in breast cancer cells directly modulates glycolysis in vitro and in vivo.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00343-5
By:
- Michaels, Aidan M.;
- Zoccarato, Anna;
- Hoare, Zoe;
- Firth, George;
- Chung, Yu Jin;
- Kuchel, Philip W.;
- Shah, Ajay M.;
- Shattock, Michael J.;
- Southworth, Richard;
- Eykyn, Thomas R.
Publication type:
Article
Hypoxia-induced NOS1 as a therapeutic target in hypercholesterolemia-related colorectal cancer.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00338-2
By:
- Qiu, Weiqing;
- Zhao, Li;
- Liu, Hua;
- Xu, Ping;
- Qian, Changlin
Publication type:
Article
Characterizing OXPHOS inhibitor-mediated alleviation of hypoxia using high-throughput live cell-imaging.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00342-6
By:
- Beerkens, Anne P. M.;
- Boreel, Daan F.;
- Nathan, James A.;
- Neuzil, Jiri;
- Cheng, Gang;
- Kalyanaraman, Balaraman;
- Hardy, Micael;
- Adema, Gosse J.;
- Heskamp, Sandra;
- Span, Paul N.;
- Bussink, Johan
Publication type:
Article
Statin use as a moderator on the association between metformin and breast cancer risk in women with type 2 diabetes mellitus.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00340-8
By:
- Zhang, Fan;
- de Bock, Geertruida H.;
- Landman, Gijs W.;
- Zhang, Qingying;
- Sidorenkov, Grigory
Publication type:
Article
Purine salvage promotes treatment resistance in H3K27M-mutant diffuse midline glioma.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00341-7
By:
- Peterson, Erik R.;
- Sajjakulnukit, Peter;
- Scott, Andrew J.;
- Heaslip, Caleb;
- Andren, Anthony;
- Wilder-Romans, Kari;
- Zhou, Weihua;
- Palavalasa, Sravya;
- Korimerla, Navyateja;
- Lin, Angelica;
- O'Brien, Alexandra;
- Kothari, Ayesha;
- Zhao, Zitong;
- Zhang, Li;
- Morgan, Meredith A.;
- Venneti, Sriram;
- Koschmann, Carl;
- Jabado, Nada;
- Lyssiotis, Costas A.;
- Castro, Maria G.
Publication type:
Article
BCAA metabolism in pancreatic cancer affects lipid balance by regulating fatty acid import into mitochondria.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00335-5
By:
- Gotvaldová, Klára;
- Špačková, Jitka;
- Novotný, Jiří;
- Baslarová, Kamila;
- Ježek, Petr;
- Rossmeislová, Lenka;
- Gojda, Jan;
- Smolková, Katarína
Publication type:
Article
Serine synthesis and catabolism in starved lung cancer and primary bronchial epithelial cells.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00337-3
By:
- Haitzmann, Theresa;
- Schindlmaier, Katharina;
- Frech, Tobias;
- Mondal, Ayusi;
- Bubalo, Visnja;
- Konrad, Barbara;
- Bluemel, Gabriele;
- Stiegler, Philipp;
- Lackner, Stefanie;
- Hrzenjak, Andelko;
- Eichmann, Thomas;
- Köfeler, Harald C.;
- Leithner, Katharina
Publication type:
Article
Dietary patterns in relation to glioma: a case–control study.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00336-4
By:
- Nemati, Mohammad;
- Shayanfar, Mehdi;
- Almasi, Fatemeh;
- Mohammad-Shirazi, Minoo;
- Sharifi, Giuve;
- Aminianfar, Azadeh;
- Esmaillzadeh, Ahmad
Publication type:
Article
Elevated expression of HIGD1A drives hepatocellular carcinoma progression by regulating polyamine metabolism through c-Myc–ODC1 nexus.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00334-6
By:
- Zhang, Haixing;
- Li, Xiaoran;
- Liu, Ziying;
- Lin, Zimo;
- Huang, Kuiyuan;
- Wang, Yiran;
- Chen, Yu;
- Liao, Leyi;
- Wu, Leyuan;
- Xie, Zhanglian;
- Hou, Jinlin;
- Zhang, Xiaoyong;
- Liu, Hongyan
Publication type:
Article
Cone photoreceptor phosphodiesterase PDE6H inhibition regulates cancer cell growth and metabolism, replicating the dark retina response.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-023-00326-y
By:
- Yalaz, Ceren;
- Bridges, Esther;
- Alham, Nasullah K.;
- Zois, Christos E.;
- Chen, Jianzhou;
- Bensaad, Karim;
- Miar, Ana;
- Pires, Elisabete;
- Muschel, Ruth J.;
- McCullagh, James S. O.;
- Harris, Adrian L.
Publication type:
Article
Deficiency of TOP1MT enhances glycolysis through the stimulation of PDK4 expression in gastric cancer.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00330-w
By:
- Wang, Hongqiang;
- Sun, Xutao;
- Yang, Chen;
- Li, Ziqi;
- Jin, Danwen;
- Zhu, Wenwen;
- Yu, Ze
Publication type:
Article
Assessment of lipolysis biomarkers in adipose tissue of patients with gastrointestinal cancer.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-023-00329-9
By:
- Tambaro, Federica;
- Imbimbo, Giovanni;
- Ferraro, Elisabetta;
- Andreini, Martina;
- Belli, Roberta;
- Amabile, Maria Ida;
- Ramaccini, Cesarina;
- Lauteri, Giulia;
- Nigri, Giuseppe;
- Muscaritoli, Maurizio;
- Molfino, Alessio
Publication type:
Article
Systemic inflammation and insulin resistance-related indicator predicts poor outcome in patients with cancer cachexia.
Published in:
Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00332-8
By:
- Ruan, Guo-Tian;
- Deng, Li;
- Xie, Hai-Lun;
- Shi, Jin-Yu;
- Liu, Xiao-Yue;
- Zheng, Xin;
- Chen, Yue;
- Lin, Shi-Qi;
- Zhang, He-Yang;
- Liu, Chen-An;
- Ge, Yi-Zhong;
- Song, Meng-Meng;
- Hu, Chun-Lei;
- Zhang, Xiao-Wei;
- Yang, Ming;
- Hu, Wen;
- Cong, Ming-Hua;
- Zhu, Li-Chen;
- Wang, Kun-Hua;
- Shi, Han-Ping
Publication type:
Article