Works matching DE "IMMUNE checkpoint proteins"

Results: 5000

Circulating T cell atlas in Moyamoya disease: insights into immunopathogenesis of cerebrovascular disorders.

Published in:

Journal of Neuroinflammation, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12974-025-03479-3

By:

Liu, Chenglong;
Li, Junsheng;
Mou, Siqi;
Pang, Yuheng;
Chan, Liujia;
He, Qiheng;
Liu, Wei;
Zhao, Zhikang;
Zhang, Bojian;
Zheng, Zhiyao;
Sun, Wei;
Shi, Xiangjun;
Zhang, Qian;
Wang, Rong;
Zhang, Yan;
Wang, Wenjing;
Zhang, Dong;
Ge, Peicong

Publication type:

Article

Lysine‐specific demethylase 1 deletion reshapes tumour microenvironment to overcome acquired resistance to anti‐programmed death 1 therapy in liver cancer.

Published in:

Clinical & Translational Medicine, 2025, v. 15, n. 5, p. 1, doi. 10.1002/ctm2.70335

By:

Liang, Chen;
Ye, Mu;
Yu, Lei;
Zhang, Peng‐Fei;
Guo, Xiao‐Jun;
Meng, Xian‐Long;
Zeng, Hai‐Ying;
Hu, Shu‐Yang;
Zhang, Dao‐Han;
Sun, Qi‐Man;
Shen, Ying‐Hao;
Cai, Jia‐Bin;
Li, Shuang‐Qi;
Chen, Zhen;
Shi, Ying‐Hong;
Ke, Ai‐Wu;
Shi, Yujiang G.;
Zhou, Jian;
Fan, Jia;
Wu, Fei‐Zhen

Publication type:

Article

ALG3 as a prognostic biomarker and mediator of PD-1 blockade resistance in hepatocellular carcinoma.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1589153

By:

Tang, Pengju;
Han, Zhenwei;
Zhao, Yiming;
Xu, Tianxin;
Zhang, Yu;
Zhu, Lirong;
Song, Fei;
Gao, Cheng;
Gong, Jinbo;
Cheng, Ji;
Wang, Chenggui;
Wang, Tianlun;
Xu, Jie;
Wang, Yu;
Chen, Zhong

Publication type:

Article

Single-cell and bulk transcriptome analyses reveal elevated amino acid metabolism promoting tumor-directed immune evasion in colorectal cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1575829

By:

Sun, Tianyue;
Chen, Yan;
Chen, Ying-Xuan

Publication type:

Article

Expression of PSMD14 in lung adenocarcinoma and its impact on immune cell infiltration and prognosis: a comprehensive analysis based on RNA and single-cell RNA sequencing.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1560693

By:

Zhang, Jing;
Sun, Bohao;
Lai, Jiabin;
Kong, Weike;
Wang, Nan;
Li, Panyuan;
Wu, Yichen;
Jiang, Zhaochang

Publication type:

Article

Presence of LILRB4 SNP rs1048801 modulates acute myeloid leukemia progression and inhibits CD4<sup>+</sup> T cells proliferation.

Published in:

Journal of Leukocyte Biology, 2025, v. 117, n. 5, p. 1, doi. 10.1093/jleuko/qiaf052

By:

Zhou, Zhiyong;
Li, Yi;
Wu, Di;
Xiao, Yiliang;
Zeng, Shuyan;
Xiao, Qiuyun;
Chen, Siqi;
Ma, Junpeng;
Yuan, Xin;
Chen, Jin;
Peng, Huiyun

Publication type:

Article

Role of TGFβ-activated cancer-associated fibroblasts in the resistance to checkpoint blockade immunotherapy.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1602452

By:

Hou, Weibin

Publication type:

Article

Antiproliferative and pro-apoptotic effects of Pseudevernia furfuracea (L.) Zopf extract and its active component physodic acid via oxidative stress and DNA damage in breast cancer cells.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1557884

By:

Sebova, Dominika;
Zilakova, Simona;
Medvecova, Viktoria;
Goga, Michal;
Frenak, Richard;
Bardelcikova, Annamaria;
Mirossay, Andrej;
Mirossay, Ladislav;
Mojzis, Jan;
Kello, Martin

Publication type:

Article

Methotrexate exerts antitumor immune activity and improves the clinical efficacy of immunotherapy in patients with solid tumors.

Published in:

Science Translational Medicine, 2025, v. 17, n. 801, p. 1, doi. 10.1126/scitranslmed.adn6921

By:

Yang, Ruirui;
Wang, Bei;
Su, Zhaoming;
Song, Ying;
Zhang, Yingying;
Liu, Yadan;
Zhang, Yinghui;
He, Changyu;
Yang, Xi;
Zhong, Feisheng;
Fu, Zunyun;
Ding, Yiluan;
Zhang, Naixia;
Li, Rui;
Chu, Shuqing;
Xu, Chuanhai;
Sun, Jian;
Shen, Haiwei;
Geng, Wei;
Zhang, Sulin

Publication type:

Article

The bibliometric analysis of research on traditional Chinese medicine regulating gut microbiota for cancer treatment from 2014 to 2024.

Published in:

Hereditas, 2025, v. 162, n. 1, p. 1, doi. 10.1186/s41065-025-00456-x

By:

Lei, Youfeng;
Shan, Yueqin;
Zhou, Danfeng;
Chen, Chunyan

Publication type:

Article

Targeting CD39 boosts PD-1 blockade antitumor therapeutic efficacy via strengthening CD8 + TILs function and recruiting B cells in cervical cancer.

Published in:

Journal of Nanobiotechnology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12951-025-03500-0

By:

Jiang, Lili;
Wu, Tong;
Qu, Xinyu;
Li, Shuqi;
Jiang, Qi'an;
Ren, Tingting;
Liang, Jiali;
Ding, Yan;
Hua, Keqin;
Tang, Zhongmin;
Qiu, Junjun

Publication type:

Article

Ferroptosis-related gene signature-based subtype identification of triple-negative breast cancer to prioritize treatment strategies.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1541119

By:

Chen, Yongzhen;
Huang, Xiaoying;
Wang, Junqi;
Hu, Chao;
Zheng, Yanan;
Wang, Yumeng;
Zheng, Shuqian;
Ji, Guozhong;
You, Qiang

Publication type:

Article

High mobility group A1 (HMGA1) promotes esophageal squamous cell carcinoma progression by inhibiting STING-mediated anti-tumor immunity.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60221-6

By:

He, Kai-Yue;
Zhao, Annie;
Guo, Jin-Rong;
Wu, Dan-Hui;
Liu, Huai;
Gao, Fan;
Liu, Meng-Jie;
Yang, Jing-Yu;
Lei, Xin-Yuan;
Li, Jun-Qi;
Zhang, Lei;
Yan, Zhen-Hua;
Ding, Qiang;
Huang, Yong-Wei;
Cui, Rutao;
Jian, Yong-Ping;
Xu, Zhi-Xiang

Publication type:

Article

Aberrant expression of PYGB as a potential therapeutic target and its associations with immune cell infiltration in lung cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1536248

By:

Sun, Kai;
Xu, De-chang;
Qin, Xia;
Xie, Fang-fang

Publication type:

Article

Intratumor heterogeneity and T cell exhaustion in primary CNS lymphoma.

Published in:

Genome Medicine, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13073-022-01110-1

By:

Heming, Michael;
Haessner, Svea;
Wolbert, Jolien;
Lu, I-Na;
Li, Xiaolin;
Brokinkel, Benjamin;
Müther, Michael;
Holling, Markus;
Stummer, Walter;
Thomas, Christian;
Schulte-Mecklenbeck, Andreas;
de Faria, Flavia;
Stoeckius, Marlon;
Hailfinger, Stephan;
Lenz, Georg;
Kerl, Kornelius;
Wiendl, Heinz;
Meyer zu Hörste, Gerd;
Grauer, Oliver M.

Publication type:

Article

Clinical and Fundamental Research Progressions on Tumor-Infiltrating Lymphocytes Therapy in Cancer.

Published in:

Vaccines, 2025, v. 13, n. 5, p. 521, doi. 10.3390/vaccines13050521

By:

Hu, Jiandong;
Jin, Mengli;
Feng, Weihong;
Nassif-Rausseo, Barbara;
Reuben, Alexandre;
Ma, Chunhua;
Lizee, Gregory;
Li, Fenge

Publication type:

Article

Programmed Cell Death-1 Expression in T-Cell Subsets in Chickens Infected with Marek's Disease Virus.

Published in:

Pathogens, 2025, v. 14, n. 5, p. 431, doi. 10.3390/pathogens14050431

By:

Sato, Jumpei;
Motai, Yoshinosuke;
Yamagami, Shunsuke;
Win, Shwe Yee;
Horio, Fumiya;
Saeki, Hikaru;
Maekawa, Naoya;
Okagawa, Tomohiro;
Konnai, Satoru;
Ohashi, Kazuhiko;
Murata, Shiro

Publication type:

Article

Spatial Heterogeneity of Intratumoral Microbiota: A New Frontier in Cancer Immunotherapy Resistance.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1261, doi. 10.3390/biomedicines13051261

By:

Tan, Qiwen;
Cao, Xiongjing;
Zou, Falong;
Wang, Hanwenchen;
Xiong, Lijuan;
Deng, Shenghe

Publication type:

Article

The Development and Assessment of a Unique Disulfidptosis-Associated lncRNA Profile for Immune Microenvironment Prediction and Personalized Therapy in Gastric Adenocarcinoma.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1224, doi. 10.3390/biomedicines13051224

By:

Zhu, Jiyue;
Zhu, Xiang;
Su, Tingting;
Zhou, Huiqing;
Wang, Shouhua;
Shi, Weibin

Publication type:

Article

Transposable Element Is Predictive of Chemotherapy- and Immunotherapy-Related Overall Survival in Glioma.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1177, doi. 10.3390/biomedicines13051177

By:

Peng, Bi;
Shen, Fan;
Chen, Ziqi;
Yu, Yongkai;
Liu, Rundong;
Zhang, Yiling;
Long, Guoxian;
Hu, Guangyuan;
Liu, Yuanhui

Publication type:

Article

The Role of Tregs in the Tumor Microenvironment.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1173, doi. 10.3390/biomedicines13051173

By:

Sato, Yohei

Publication type:

Article

G-Quadruplexes in Tumor Immune Regulation: Molecular Mechanisms and Therapeutic Prospects in Gastrointestinal Cancers.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1057, doi. 10.3390/biomedicines13051057

By:

Zhou, Yunxia;
Xu, Difei;
Zhang, Ying;
Zhou, Huaixiang

Publication type:

Article

The Interplay Between DNA Repair and the Immune Microenvironment in Pancreatic Cancer.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1031, doi. 10.3390/biomedicines13051031

By:

Ciner, Aaron;
Hosein, Peter J.;
Jiang, Yixing;
Rassool, Feyruz

Publication type:

Article

Downregulation of cGAS/STING expression in tumor cells by cancer-associated fibroblasts in colorectal cancer.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-03924-6

By:

Kanoda, Ryo;
Nakajima, Shotaro;
Okayama, Hirokazu;
Kaneta, Akinao;
Chida, Shun;
Matsumoto, Takuro;
Saito, Katsuharu;
Kikuchi, Tomohiro;
Maruyama, Yuya;
Suzuki, Hiroya;
Mimura, Kosaku;
Saito, Motonobu;
Hanayama, Hiroyuki;
Sakamoto, Wataru;
Momma, Tomoyuki;
Saze, Zenichiro;
Kono, Koji

Publication type:

Article

NOX4 as an emerging prognostic and immunological biomarker across pan-cancer analyses.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-03499-2

By:

Liu, Yusheng;
Wu, Chunying;
Wang, Qiang;
Zhao, Xiaoshan;
Jiang, Xuefeng

Publication type:

Article

SMARCB1 Deficiency as a Driver of the Hallmarks of Cancer in Rhabdoid Tumours: Novel Insights into Dysregulated Energy Metabolism, Emerging Targets, and Ongoing Clinical Trials.

Published in:

Metabolites (2218-1989), 2025, v. 15, n. 5, p. 304, doi. 10.3390/metabo15050304

By:

Shakerdi, Abdul L.;
Pidgeon, Graham P.

Publication type:

Article

Tumor-Associated Macrophages: Polarization, Immunoregulation, and Immunotherapy.

Published in:

Cells (2073-4409), 2025, v. 14, n. 10, p. 741, doi. 10.3390/cells14100741

By:

Saeed, Abdullah Farhan

Publication type:

Article

CD99: A Key Regulator in Immune Response and Tumor Microenvironment.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 632, doi. 10.3390/biom15050632

By:

Manara, Maria Cristina;
Fiori, Valentina;
Sparti, Angelo;
Scotlandi, Katia

Publication type:

Article

Precision Targeting in Metastatic Prostate Cancer: Molecular Insights to Therapeutic Frontiers.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 625, doi. 10.3390/biom15050625

By:

Kwon, Whi-An;
Joung, Jae Young

Publication type:

Article

Unsupervised Clustering of Cell Populations in Germinal Centers Using Multiplexed Immunofluorescence.

Published in:

Biology (2079-7737), 2025, v. 14, n. 5, p. 530, doi. 10.3390/biology14050530

By:

Burgermeister, Simon;
Orfanakis, Michail;
Georgakis, Spiros;
Brenna, Cloe;
Lindsay, Helen;
Fenwick, Craig;
Pantaleo, Giuseppe;
Gottardo, Raphael;
Petrovas, Constantinos

Publication type:

Article

Decoding CD24: Roles of chemoradiotherapy resistance and potential as therapeutic targets.

Published in:

Oncology Research, 2025, v. 33, n. 6, p. 1347, doi. 10.32604/or.2025.059327

By:

HONG, YU;
TANG, YUNXIANG;
ZHOU, WENYAN;
LUO, HANYUE;
BU, LINLIN;
QIU, HUI;
WU, QIUJI

Publication type:

Article

Computational Design of a Bicyclic Peptide Inhibitor Targeting the ICOS/ICOS‐L Protein–Protein Interaction.

Published in:

Chemical Biology & Drug Design, 2025, v. 105, n. 5, p. 1, doi. 10.1111/cbdd.70117

By:

Calvo‐Barreiro, Laura;
Secor, Maxim;
Damjanovic, Jovan;
Abdel‐Rahman, Somaya A.;
Lin, Yu‐Shan;
Gabr, Moustafa

Publication type:

Article

Soluble Immune Checkpoints Associated With Disease Activity and Treatment Response in GD and TED.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2025, v. 110, n. 6, p. 1537, doi. 10.1210/clinem/dgae763

By:

Yin, Qinglei;
Zhu, Tianyi;
Song, Dalong;
Fang, Sijie;
Zhou, Huifang;
Guan, Haixia

Publication type:

Article

HIV, Sepsis, and Postdischarge Mortality in Sub-Saharan Africa.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2025, v. 211, n. 6, p. 1103, doi. 10.1164/rccm.202411-2237LE

By:

Al-Ward, Hisham;
Alnadhary, Alaa;
Chen, Wei;
Sun, Yi Eve

Publication type:

Article

Prognostic Value of B7-H3 and a Novel Scoring System in Localized Renal Cell Carcinoma.

Published in:

Medicina (1010660X), 2025, v. 61, n. 5, p. 867, doi. 10.3390/medicina61050867

By:

Özalp, Faruk Recep;
Yörükoğlu, Kutsal;
Çalışkan Yıldırım, Eda;
Uzun, Mehmet;
Demirciler, Erkut;
Semiz, Hüseyin Salih

Publication type:

Article

Treg Control of CD80/CD86 Expression Mediates Immune System Homeostasis.

Published in:

European Journal of Immunology, 2025, v. 55, n. 5, p. 1, doi. 10.1002/eji.202551771

By:

Kim, Yong‐Hee;
Panda, Abir K.;
Shevach, Ethan M.

Publication type:

Article

Thymidine kinase 1 indicates resistance to immune checkpoint plus tyrosine kinase inhibition in renal cell carcinoma.

Published in:

Cellular Oncology (2211-3428), 2025, v. 48, n. 3, p. 775, doi. 10.1007/s13402-025-01048-7

By:

Wang, Jiajun;
Xu, Xianglai;
Wang, Ying;
Zhu, Yanjun

Publication type:

Article

Immunological features of various molecular subtypes of cervical cancer and their prognostic implications in the context of disulfidptosis.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1574911

By:

Yao, Yadan;
Yang, Xiaomin;
Fu, Yuanxin;
Zhang, Yinmin

Publication type:

Article

Unraveling the immune evasion mechanisms in the tumor microenvironment of head and neck squamous cell carcinoma.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1597202

By:

Zhao, Xuri;
Zhu, Yaping;
He, Youya;
Gu, Weiyan;
Zhou, Qi;
Jin, Bei;
Chen, Shenguo;
Lin, Haisheng

Publication type:

Article

Prognosis of cholangiocarcinoma patients based on multiple patterns of programmed cell death, integrated analysis of the immune microenvironment and drug sensitivity.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1457204

By:

Xu, Yupeng;
Sun, Jian;
Yan, Xin;
Mao, Zhenliao;
Chen, Yiming

Publication type:

Article

Immune Modulation During Treatment with Enzalutamide Alone or with Radium-223 in Patients with Castration Resistant Prostate Cancer.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1730, doi. 10.3390/cancers17101730

By:

Zang, Peter D.;
Da Silva, Diane M.;
Liu, Zhang-Xu;
Kandukuri, Shivani;
Tsao-Wei, Denice;
D'Souza, Anishka;
Kast, W. Martin;
Pal, Sumanta K.;
Kefauver, Cheryl;
Juanqueira, Maribel;
Yang, Lixin;
Quinn, David I.;
Dorff, Tanya B.

Publication type:

Article

Current and Emerging Insights into the Causes, Immunopathogenesis, and Treatment of Cutaneous Squamous Cell Carcinoma.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1702, doi. 10.3390/cancers17101702

By:

Anderson, Ronald;
Mkhize, Nomzamo M.;
Kgokolo, Mahlatse M. C.;
Steel, Helen C.;
Rossouw, Theresa M.;
Anderson, Lindsay;
Rapoport, Bernardo L.

Publication type:

Article

TERT promoter methylation predicts overall survival, immune cell infiltration and response to immunotherapy in clear cell renal cell carcinoma.

Published in:

Clinical Epigenetics, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13148-025-01897-x

By:

Guan, Xinyu;
Meng, Jiahao;
Yi, Wenjun;
Ye, Kun;
Gao, Hongyu;
Hong, Yue;
Qu, Limeng;
Ding, Shirong;
Long, Qian

Publication type:

Article

The Spatial Proximity of CD8 + FoxP3 + PD-1 + Cells to Tumor Cells: A More Accurate Predictor of Immunotherapy Outcomes in Advanced Non-Small-Cell Lung Cancer.

Published in:

Current Oncology, 2025, v. 32, n. 5, p. 262, doi. 10.3390/curroncol32050262

By:

Hu, Zijuan;
Hu, Zhihuang;
Chen, Keji;
Huang, Huixia;
Zhong, Xinyang;
Wang, Yaxian;
Chen, Jiayu;
He, Xuefeng;
Shi, Di;
Zeng, Yupeng;
Li, Jiwei;
Zhou, Xiaoyan;
Wei, Ping

Publication type:

Article

Integrative Analysis of Immune- and Metabolism-Related Genes Identifies Robust Prognostic Signature and PYCR1 as a Carcinogenic Regulator in Clear Cell Renal Cell Carcinoma.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4953, doi. 10.3390/ijms26104953

By:

Zhao, Guo;
Ding, Jiatong;
Ma, Jiaxiu;
Jiang, Yale;
Wang, Yuning;
Wang, Shuhang;
Li, Ning

Publication type:

Article

A Comprehensive Review of Long Non-Coding RNAs in the Cancer–Immunity Cycle: Mechanisms and Therapeutic Implications.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4821, doi. 10.3390/ijms26104821

By:

Perez-Medina, Mario;
Benito-Lopez, Jesus J.;
Aguilar-Cazares, Dolores;
Lopez-Gonzalez, Jose S.

Publication type:

Article

NetLnc: A Network-Based Computational Framework to Identify Immune Checkpoint-Related lncRNAs for Immunotherapy Response in Melanoma.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4557, doi. 10.3390/ijms26104557

By:

Lu, Qianyi;
Li, Jian;
Chen, Wenli;
Wang, Zhuoru;
Wang, Di;
Liu, Chenyu;
Sun, Yue;
Jiang, Han;
Zhang, Caiyu;
Chang, Yetong;
Zhou, Jiajun;
Wu, Xiaohong;
Gao, Yue;
Ning, Shangwei

Publication type:

Article

Molecular Dynamics-Guided Repositioning of FDA-Approved Drugs for PD-L1 Inhibition with In Vitro Anticancer Potential.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4497, doi. 10.3390/ijms26104497

By:

Jiang, Dejun;
Yoou, Myoung-Schook;
Cho, Sungjoon;
Choi, Youngjin

Publication type:

Article

Identification of genetically engineered strategies to manipulate nano-platforms presenting immunotherapeutic ligands for alleviating primary ovarian insufficiency progression.

Published in:

Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02226-8

By:

Zhou, Guannan;
Gu, Yuanyuan;
Zhang, Menglei;
Ding, Jingxin;
Lu, Guanming;
Hua, Keqin;
Shen, Fang

Publication type:

Article

Integrative transcriptomic and single-cell analysis reveals IL27RA as a key immune regulator and therapeutic indicator in breast cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02811-w

By:

Chen, Yi;
Anwar, Munawar;
Wang, Xiaoli;
Zhang, Boxiang;
Ma, Binlin

Publication type:

Article