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Efficacy of an Immunotherapy Combining Immunogenic Chimeric Protein Plus Adjuvant and Amphotericin B against Murine Visceral Leishmaniasis.
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- Biology (2079-7737), 2023, v. 12, n. 6, p. 851, doi. 10.3390/biology12060851
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- Article
Peptide Vaccines for Leishmaniasis.
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- Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.01043
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- Article
In vitro and in vivo antileishmanial activity of β-acetyl-digitoxin, a cardenolide of Digitalis lanata potentially useful to treat visceral leishmaniasis.
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- Parasite (1252607X), 2021, v. 28, p. 1, doi. 10.1051/parasite/2021036
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- Article
Immunization with recombinant LiHyp1 protein plus adjuvant is protective against tegumentary leishmaniasis.
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- Parasitology Research, 2023, v. 122, n. 12, p. 2917, doi. 10.1007/s00436-023-07981-6
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- Article
Digitoxigenin presents an effective and selective antileishmanial action against Leishmania infantum and is a potential therapeutic agent for visceral leishmaniasis.
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- Parasitology Research, 2021, v. 120, n. 1, p. 321, doi. 10.1007/s00436-020-06971-2
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Liver infusion tryptose (LIT): the best choice for growth, viability, and infectivity of Leishmania infantum parasites.
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- Parasitology Research, 2020, v. 119, n. 12, p. 4185, doi. 10.1007/s00436-020-06893-z
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Evaluation of the protective efficacy of a Leishmania protein associated with distinct adjuvants against visceral leishmaniasis and in vitro immunogenicity in human cells.
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- Parasitology Research, 2020, v. 119, n. 8, p. 2609, doi. 10.1007/s00436-020-06752-x
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Comparative analysis of real-time PCR assays in the detection of canine visceral leishmaniasis.
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- Parasitology Research, 2018, v. 117, n. 10, p. 3341, doi. 10.1007/s00436-018-6038-9
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Evaluation of a hypothetical protein for serodiagnosis and as a potential marker for post-treatment serological evaluation of tegumentary leishmaniasis patients.
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- Parasitology Research, 2017, v. 116, n. 4, p. 1197, doi. 10.1007/s00436-017-5397-y
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- Article
An 8-hydroxyquinoline-containing polymeric micelle system is effective for the treatment of murine tegumentary leishmaniasis.
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- Parasitology Research, 2016, v. 115, n. 11, p. 4083, doi. 10.1007/s00436-016-5181-4
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- Article
A new Leishmania-specific hypothetical protein and its non-described specific B cell conformational epitope applied in the serodiagnosis of canine visceral leishmaniasis.
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- Parasitology Research, 2016, v. 115, n. 4, p. 1649, doi. 10.1007/s00436-016-4904-x
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- Article
Immunotherapy Using Immunogenic Mimotopes Selected by Phage Display plus Amphotericin B Inducing a Therapeutic Response in Mice Infected with Leishmania amazonensis.
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- Pathogens, 2023, v. 12, n. 2, p. 314, doi. 10.3390/pathogens12020314
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- Article
LBMPL Vaccine Therapy Induces Progressive Organization of the Spleen Microarchitecture, Improved Th1 Adaptative Immune Response and Control of Parasitism in Leishmania infantum Naturally Infected Dogs.
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- Pathogens, 2022, v. 11, n. 9, p. N.PAG, doi. 10.3390/pathogens11090974
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Synthetic Peptides Selected by Immunoinformatics as Potential Tools for the Specific Diagnosis of Canine Visceral Leishmaniasis.
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- Microorganisms, 2024, v. 12, n. 5, p. 906, doi. 10.3390/microorganisms12050906
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Multicomponent LBSap vaccine displays immunological and parasitological profiles similar to those of Leish-Tec® and Leishmune® vaccines against visceral leishmaniasis.
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- Parasites & Vectors, 2016, v. 9, p. 1, doi. 10.1186/s13071-016-1752-6
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Clinical, hematological and biochemical alterations in hamster (Mesocricetus auratus) experimentally infected with Leishmania infantum through different routes of inoculation.
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- Parasites & Vectors, 2016, v. 9, p. 1, doi. 10.1186/s13071-016-1464-y
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- Article
Neutrophil properties in healthy and Leishmania infantum-naturally infected dogs.
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- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-42687-9
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- Article
Development of an immunogen containing CD4<sup>+</sup>/CD8<sup>+</sup> T-cell epitopes for the prophylaxis of tegumentary leishmaniasis.
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- Applied Microbiology & Biotechnology, 2022, v. 106, n. 12, p. 4627, doi. 10.1007/s00253-022-12033-7
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Recent advances and new strategies on leishmaniasis treatment.
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- Applied Microbiology & Biotechnology, 2020, v. 104, n. 21, p. 8965, doi. 10.1007/s00253-020-10856-w
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Recent advances and new strategies in Leishmaniasis diagnosis.
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- Applied Microbiology & Biotechnology, 2020, v. 104, n. 19, p. 8105, doi. 10.1007/s00253-020-10846-y
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A candidate vaccine for human visceral leishmaniasis based on a specific T cell epitope-containing chimeric protein protects mice against Leishmania infantum infection.
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- NPJ Vaccines, 2020, v. 5, n. 1, p. 1, doi. 10.1038/s41541-020-00224-0
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The Use of an Adjuvant System Improves Innate and Adaptive Immune Response When Associated with a Leishmania (Viannia) braziliensis Antigen in a Vaccine Candidate against L. (Leishmania) infantum Infection.
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- Vaccines, 2023, v. 11, n. 2, p. 395, doi. 10.3390/vaccines11020395
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A Recombinant Chimeric Protein-Based Vaccine Containing T-Cell Epitopes from Amastigote Proteins and Combined with Distinct Adjuvants, Induces Immunogenicity and Protection against Leishmania infantum Infection.
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- Vaccines, 2022, v. 10, n. 7, p. N.PAG, doi. 10.3390/vaccines10071146
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Phase I and II Clinical Trial Comparing the LBSap, Leishmune ® , and Leish-Tec ® Vaccines against Canine Visceral Leishmaniasis.
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- Vaccines, 2020, v. 8, n. 4, p. 690, doi. 10.3390/vaccines8040690
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- Article
Liposomal Formulation of ChimeraT, a Multiple T-Cell Epitope-Containing Recombinant Protein, Is a Candidate Vaccine for Human Visceral Leishmaniasis.
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- Vaccines, 2020, v. 8, n. 2, p. 289, doi. 10.3390/vaccines8020289
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Chimeric Vaccines Designed by Immunoinformatics-Activated Polyfunctional and Memory T cells that Trigger Protection against Experimental Visceral Leishmaniasis.
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- Vaccines, 2020, v. 8, n. 2, p. 252, doi. 10.3390/vaccines8020252
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Immunization with the HisAK70 DNA Vaccine Induces Resistance against Leishmania Amazonensis Infection in BALB/c Mice.
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- Vaccines, 2019, v. 7, n. 4, p. 183, doi. 10.3390/vaccines7040183
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Synthetic Peptides Elicit Strong Cellular Immunity in Visceral Leishmaniasis Natural Reservoir and Contribute to Long-Lasting Polyfunctional T-Cells in BALB/c Mice.
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- Vaccines, 2019, v. 7, n. 4, p. 162, doi. 10.3390/vaccines7040162
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Replacement of Leishmania (Leishmania) infantum Populations in an Endemic Focus of Visceral Leishmaniasis in Brazil.
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- Frontiers in Cellular & Infection Microbiology, 2022, v. 12, p. 1, doi. 10.3389/fcimb.2022.900084
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Immunotherapy Combining Mimotopes Selected by Phage Display Plus Amphotericin B Is Effective for Treatment Against Visceral Leishmaniasis.
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- Parasite Immunology, 2024, v. 46, n. 5, p. 1, doi. 10.1111/pim.13037
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Leishmania LiHyC protein is immunogenic and induces protection against visceral leishmaniasis.
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- Parasite Immunology, 2022, v. 44, n. 8, p. 1, doi. 10.1111/pim.12921
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Establishment of monoclonal antibodies to evaluate the cellular immunity in a hamster model of L infantum infection.
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- Parasite Immunology, 2021, v. 43, n. 4, p. 1, doi. 10.1111/pim.12823
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Parasitological and immunological evaluation of a novel chemotherapeutic agent against visceral leishmaniasis.
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- Parasite Immunology, 2020, v. 42, n. 12, p. 1, doi. 10.1111/pim.12784
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Performance of the Wondfo 2019-nCoV antigen test using self-collected nasal versus professional-collected nasopharyngeal swabs in symptomatic SARS-CoV-2 infection.
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- Diagnosis (2194-802X), 2022, v. 9, n. 3, p. 398, doi. 10.1515/dx-2022-0003
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- Article
A Vaccine Therapy for Canine Visceral Leishmaniasis Promoted Significant Improvement of Clinical and Immune Status with Reduction in Parasite Burden.
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- Frontiers in Immunology, 2017, v. 8, p. 1, doi. 10.3389/fimmu.2017.00217
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Prevalence and Factors Associated with Leishmania infantum Infection of Dogs from an Urban Area of Brazil as Identified by Molecular Methods.
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- PLoS Neglected Tropical Diseases, 2011, v. 5, n. 8, p. 1, doi. 10.1371/journal.pntd.0001291
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- Article
Prevalence and Factors Associated with Leishmania infantum Infection of Dogs from an Urban Area of Brazil as Identified by Molecular Methods.
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- PLoS Neglected Tropical Diseases, 2011, v. 5, n. 8, p. 1, doi. 10.1371/journal.pntd.0001291
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- Article
Evaluation of Change in Canine Diagnosis Protocol Adopted by the Visceral Leishmaniasis Control Program in Brazil and a New Proposal for Diagnosis.
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- PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0091009
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Clinical Forms of Canine Visceral Leishmaniasis in Naturally <i>Leishmania infantum</i>–Infected Dogs and Related Myelogram and Hemogram Changes.
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- PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0082947
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Performance of LBSap Vaccine after Intradermal Challenge with L infantum and Saliva of Lu. longipalpis: Immunogenicity and Parasitological Evaluation.
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- PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0049780
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Parasite Burden in Hamsters Infected with Two Different Strains of Leishmania (Leishmania) infantum: "Leishman Donovan Units" versus Real-Time PCR.
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- PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0047907
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Acarbose presents in vitro and in vivo antileishmanial activity against Leishmania infantum and is a promising therapeutic candidate against visceral leishmaniasis.
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- Medical Microbiology & Immunology, 2021, v. 210, n. 2/3, p. 133, doi. 10.1007/s00430-021-00707-4
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Immunotherapy and immunochemotherapy in visceral leishmaniasis: promising treatments for this neglected disease.
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- Frontiers in Immunology, 2014, v. 5, p. 1, doi. 10.3389/fimmu.2014.00272
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Immunotherapy and immunochemotherapy in visceral leishmaniasis: promising treatments for this neglected disease.
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- Frontiers in Immunology, 2014, v. 5, p. 1, doi. 10.3389/fimmu.2014.00272
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- Article
LBSapSal-vaccinated dogs exhibit increased circulating T-lymphocyte subsets (CD4+ and CD8+) as well as a reduction of parasitism after challenge with Leishmania infantum plus salivary gland of Lutzomyia longipalpis.
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- Parasites & Vectors, 2014, v. 7, n. 1, p. 1, doi. 10.1186/1756-3305-7-61
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- Article
Comparative genomics of canine-isolated Leishmania (Leishmania) amazonensis from an endemic focus of visceral leishmaniasis in Governador Valadares, southeastern Brazil.
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- Scientific Reports, 2017, p. 40804, doi. 10.1038/srep40804
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- Article
Impact of LbSapSal Vaccine in Canine Immunological and Parasitological Features before and after Leishmania chagasi-Challenge.
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- PLoS ONE, 2016, v. 11, n. 8, p. 1, doi. 10.1371/journal.pone.0161169
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Selection strategy of phage-displayed immunogens based on an in vitro evaluation of the Th1 response of PBMCs and their potential use as a vaccine against Leishmania infantum infection.
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- Parasites & Vectors, 2017, v. 10, p. 1, doi. 10.1186/s13071-017-2576-8
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Exogenous surfactant reduces inflammation and redox imbalance in rats under prone or supine mechanical ventilation.
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- Experimental Biology & Medicine, 2023, v. 248, n. 12, p. 1074, doi. 10.1177/15353702231160352
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- Article