Works matching DE "STEROL regulatory element-binding proteins"
Results: 424
Regulation and targeting of SREBP-1 in hepatocellular carcinoma.
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- Cancer & Metastasis Reviews, 2024, v. 43, n. 2, p. 673, doi. 10.1007/s10555-023-10156-5
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The CREB coactivator CRTC2 controls hepatic lipid metabolism by regulating SREBP1.
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- Nature, 2015, v. 524, n. 7564, p. 243, doi. 10.1038/nature14557
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Phosphatidic acid directly activates mTOR and then regulates SREBP to promote ganoderic acid biosynthesis under heat stress in Ganoderma lingzhi.
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- Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07225-y
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Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity.
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- Nature Immunology, 2013, v. 14, n. 5, p. 489, doi. 10.1038/ni.2570
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Sorting (Nexin-13) out Novel Insights into Endolysosomal Cholesterol Export.
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- Contact (25152564), 2022, v. 5, p. 1, doi. 10.1177/25152564221114513
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The effect of different boron compounds on nutrient digestibility, intestinal nutrient transporters, and liver lipid metabolism.
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- Turkish Journal of Medical Sciences, 2023, v. 53, n. 3, p. 619, doi. 10.55730/1300-0144.5624
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A lactate-SREBP2 signaling axis drives tolerogenic dendritic cell maturation and promotes cancer progression.
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- Science Immunology, 2024, v. 9, n. 95, p. 1, doi. 10.1126/sciimmunol.adi4191
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Antioxidant-rich Tamarindus indica L. leaf extract reduced high-fat diet-induced obesity in rat through modulation of gene expression.
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- Clinical Phytoscience, 2020, v. 6, n. 1, p. N.PAG, doi. 10.1186/s40816-020-00213-9
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Bisphenol S Induces Lipid Metabolism Disorders in HepG2 and SK-Hep-1 Cells via Oxidative Stress.
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- Toxics, 2025, v. 13, n. 1, p. 44, doi. 10.3390/toxics13010044
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Relevance of lipogenesis and AMPK/Akt/mTOR signaling pathway in endometrıal cancer.
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- European Review for Medical & Pharmacological Sciences, 2021, v. 25, n. 2, p. 687
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Identification of Potential New Genes Related to the SREBP Pathway in Xanthophyllomyces dendrorhous.
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- Biomolecules (2218-273X), 2024, v. 14, n. 7, p. 778, doi. 10.3390/biom14070778
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Key Molecules of Fatty Acid Metabolism in Gastric Cancer.
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- Biomolecules (2218-273X), 2022, v. 12, n. 5, p. 706, doi. 10.3390/biom12050706
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Hypoxia-altered cholesterol homeostasis enhances the expression of interferon-stimulated genes upon SARS-CoV-2 infections in monocytes.
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- Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1121864
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Sterol Regulatory Element-Binding Protein-1c Regulates Inflammasome Activation in Gingival Fibroblasts Infected with High-Glucose-Treated Porphyromonas gingivalis.
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- Frontiers in Cellular & Infection Microbiology, 2016, v. 6, p. 1, doi. 10.3389/fcimb.2016.00195
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Ezetimibe increases intestinal expression of the LDL receptor gene in dyslipidaemic men with insulin resistance.
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- Diabetes, Obesity & Metabolism, 2016, v. 18, n. 12, p. 1226, doi. 10.1111/dom.12749
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The Carbonic Anhydrase Inhibitor Dorzolamide Stimulates the Differentiation of Human Meibomian Gland Epithelial Cells.
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- Current Eye Research, 2020, v. 45, n. 12, p. 1604, doi. 10.1080/02713683.2020.1772832
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UBC12‐mediated SREBP‐1 neddylation worsens metastatic tumor prognosis.
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- International Journal of Cancer, 2020, v. 147, n. 9, p. 2550, doi. 10.1002/ijc.33113
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Histone H2A Lys130 acetylation epigenetically regulates androgen production in prostate cancer.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38887-7
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SREBP modulates the NADP<sup>+</sup>/NADPH cycle to control night sleep in Drosophila.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-022-35577-8
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Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28240-9
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SREBP2-dependent lipid gene transcription enhances the infection of human dendritic cells by Zika virus.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33041-1
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miR-33a Inhibits the Differentiation of Bovine Preadipocytes through the IRS2–Akt Pathway.
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- Genes, 2023, v. 14, n. 2, p. 529, doi. 10.3390/genes14020529
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Transcriptome Analysis Reveals That SREBP Modulates a Large Repertoire of Genes Involved in Key Cellular Functions in Penaeus vannamei , although the Majority of the Dysregulated Genes Are Unannotated.
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- Genes, 2022, v. 13, n. 11, p. 2057, doi. 10.3390/genes13112057
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New insights into the activation of sterol regulatory element-binding proteins by proteolytic processing.
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- Biomolecular Concepts, 2013, v. 4, n. 4, p. 417, doi. 10.1515/bmc-2013-0009
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The kinase PKD3 provides negative feedback on cholesterol and triglyceride synthesis by suppressing insulin signaling.
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- Science Signaling, 2019, v. 12, n. 593, p. 1, doi. 10.1126/scisignal.aav9150
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The SCF<sub>β-TRCP</sub> E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis.
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- Science Signaling, 2017, v. 10, n. 460, p. 1, doi. 10.1126/scisignal.aah4117
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Molecular mechanism of ectopic lipid accumulation induced by methylglyoxal via activation of the NRF2/PI3K/AKT pathway implicates renal lipotoxicity caused by diabetes mellitus.
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- PLoS ONE, 2024, v. 19, n. 10, p. 1, doi. 10.1371/journal.pone.0306575
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Gypenoside XIII regulates lipid metabolism in HepG2 hepatocytes and ameliorates nonalcoholic steatohepatitis in mice.
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- Kaohsiung Journal of Medical Sciences, 2024, v. 40, n. 3, p. 280, doi. 10.1002/kjm2.12795
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mTOR regulates fatty infiltration through SREBP-1 and PPARγ after a combined massive rotator cuff tear and suprascapular nerve injury in rats.
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- Journal of Orthopaedic Research, 2013, v. 31, n. 5, p. 724, doi. 10.1002/jor.22254
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Sterol Regulatory Element-Binding Protein Sre1 Mediates the Development and Pathogenicity of the Grey Mould Fungus Botrytis cinerea.
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- International Journal of Molecular Sciences, 2025, v. 26, n. 3, p. 1365, doi. 10.3390/ijms26031365
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Exploring Molecular Mechanisms of Liver Fibrosis.
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- International Journal of Molecular Sciences, 2025, v. 26, n. 1, p. 326, doi. 10.3390/ijms26010326
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Deciphering the Role of the SREBF1 Gene in the Transcriptional Regulation of Porcine Adipogenesis Using CRISPR/Cas9 Editing.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 23, p. 12677, doi. 10.3390/ijms252312677
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Lycium chinense Mill Induces Anti-Obesity and Anti-Diabetic Effects In Vitro and In Vivo.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 16, p. 8572, doi. 10.3390/ijms25168572
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Thermoneutrality Inhibits Thermogenic Markers and Exacerbates Nonalcoholic Fatty Liver Disease in Mice.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 15, p. 8482, doi. 10.3390/ijms25158482
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Puerarin Modulates Hepatic Farnesoid X Receptor and Gut Microbiota in High-Fat Diet-Induced Obese Mice.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 10, p. 5274, doi. 10.3390/ijms25105274
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Narirutin-Rich Celluclast Extract from Mandarin (Citrus unshiu) Peel Alleviates High-Fat Diet-Induced Obesity and Promotes Energy Metabolism in C57BL/6 Mice.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 8, p. 4475, doi. 10.3390/ijms25084475
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Timosaponin A3 Induces Anti-Obesity and Anti-Diabetic Effects In Vitro and In Vivo.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 5, p. 2914, doi. 10.3390/ijms25052914
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Cornelian Cherry (Cornus mas L.) Fruit Extract Lowers SREBP-1c and C/EBPα in Liver and Alters Various PPAR-α, PPAR-γ, LXR-α Target Genes in Cholesterol-Rich Diet Rabbit Model.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 2, p. 1199, doi. 10.3390/ijms25021199
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Uncovering the Lipid Web: Discovering the Multifaceted Roles of Lipids in Human Diseases and Therapeutic Opportunities.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 17, p. 13223, doi. 10.3390/ijms241713223
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Aerobic Exercise Facilitates the Nuclear Translocation of SREBP2 by Activating AKT/SEC24D to Contribute Cholesterol Homeostasis for Improving Cognition in APP/PS1 Mice.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 16, p. 12847, doi. 10.3390/ijms241612847
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Effects of miR-33 Deficiency on Metabolic and Cardiovascular Diseases: Implications for Therapeutic Intervention.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 13, p. 10777, doi. 10.3390/ijms241310777
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α-Tocopherol-13′-Carboxychromanol Induces Cell Cycle Arrest and Cell Death by Inhibiting the SREBP1-SCD1 Axis and Causing Imbalance in Lipid Desaturation.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 11, p. 9229, doi. 10.3390/ijms24119229
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Different Fatty Acid Supplementation in Low-Protein Diets Regulate Nutrient Utilization and Lipid and Amino Acid Metabolism in Weaned Pigs Model.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 10, p. 8501, doi. 10.3390/ijms24108501
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Heat-Killed Enterococcus faecalis Inhibit FL83B Hepatic Lipid Accumulation and High Fat Diet-Induced Fatty Liver Damage in Rats by Activating Lipolysis through the Regulation the AMPK Signaling Pathway.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 5, p. 4486, doi. 10.3390/ijms24054486
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Cholesterol-Lowering Activity of Vitisin A Is Mediated by Inhibiting Cholesterol Biosynthesis and Enhancing LDL Uptake in HepG2 Cells.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 4, p. 3301, doi. 10.3390/ijms24043301
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Lactobacillus sakei MJM60958 as a Potential Probiotic Alleviated Non-Alcoholic Fatty Liver Disease in Mice Fed a High-Fat Diet by Modulating Lipid Metabolism, Inflammation, and Gut Microbiota.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 21, p. 13436, doi. 10.3390/ijms232113436
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Activation of ADRB2/PKA Signaling Pathway Facilitates Lipid Synthesis in Meibocytes, and Beta-Blocker Glaucoma Drug Impedes PKA-Induced Lipid Synthesis by Inhibiting ADRB2.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 16, p. 9478, doi. 10.3390/ijms23169478
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Targeting the SREBP-1/Hsa-Mir-497/SCAP/FASN Oncometabolic Axis Inhibits the Cancer Stem-like and Chemoresistant Phenotype of Non-Small Cell Lung Carcinoma Cells.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 13, p. 7283, doi. 10.3390/ijms23137283
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Leptin Silencing Attenuates Lipid Accumulation through Sterol Regulatory Element-Binding Protein 1 Inhibition in Nasopharyngeal Carcinoma.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 10, p. 5700, doi. 10.3390/ijms23105700
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Quercetin Reduces Lipid Accumulation in a Cell Model of NAFLD by Inhibiting De Novo Fatty Acid Synthesis through the Acetyl-CoA Carboxylase 1/AMPK/PP2A Axis.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 3, p. 1044, doi. 10.3390/ijms23031044
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